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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105133242.

Bicc1 ribonucleoprotein complexes specifying organ laterality are licensed by ANKS6-induced structural remodeling of associated ANKS3

Benjamin Rothé, Yayoi Ikawa, Zhidian Zhang, Takanobu A. Katoh, Eriko Kajikawa, Katsura Minegishi, Sai Xiaorei, Simon Fortier, Matteo Dal Peraro, Hiroshi Hamada, Daniel B. Constam

PLoS Biol. 2023 Sep; 21(9): e3002302. Published online 2023 Sep 21. doi: 10.1371/journal.pbio.3002302

PMCID:: PMC10513324

Abstract Article PDF–3.1M

Select item 92175323.

Expression and Regulatory Network Analysis of BICC1 for Aged Sca-1-Positive Bone Narrow Mesenchymal Stem Cells

Zhongshuang Liu, Chuntao Ou, Siyu Xiang, Qi Xie, Shuangjiang Che, Dandi Zhang, Lingna Meng, Ziqi Liu, Guohong Zhang, Ying Wang, Yun Huang, Wenjing Zhang, Yongqiang Deng

Dis Markers. 2022; 2022: 4759172. Published online 2022 Jun 15. doi: 10.1155/2022/4759172

PMCID:: PMC9217532

Abstract Article PDF–1.1M

Select item 82493884.

Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex

Katsura Minegishi, Benjamin Rothé, Kaoru R. Komatsu, Hiroki Ono, Yayoi Ikawa, Hiromi Nishimura, Takanobu A. Katoh, Eriko Kajikawa, Xiaorei Sai, Emi Miyashita, Katsuyoshi Takaoka, Kana Bando, Hiroshi Kiyonari, Tadashi Yamamoto, Hirohide Saito, Daniel B. Constam, Hiroshi Hamada

Nat Commun. 2021; 12: 4071. Published online 2021 Jul 1. doi: 10.1038/s41467-021-24295-2

PMCID:: PMC8249388

Abstract Article PDF–4.7M

Select item 81264795.

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model

Leticia L. Niborski, Mélanie Paces-Fessy, Pierbruno Ricci, Adeline Bourgeois, Pedro Magalhães, Maria Kuzma-Kuzniarska, Celine Lesaulnier, Martin Reczko, Edwige Declercq, Petra Zürbig, Alain Doucet, Muriel Umbhauer, Silvia Cereghini

Dis Model Mech. 2021 May 1; 14(5): dmm047498. Published online 2021 May 4. doi: 10.1242/dmm.047498

PMCID:: PMC8126479

Abstract Article

Select item 63984476.

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto

Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146

PMCID:: PMC6398447

Abstract Article

Select item 62316387.

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

Afzal M. Dogar, Ramona Pauchard-Batschulat, Barbara Grisoni-Neupert, Larry Richman, Alexandra Paillusson, Sylvain Pradervand, Otto Hagenbüchle, Giovanna Ambrosini, Christoph D. Schmid, Philipp Bucher, Lukas C. Kühn

PLoS One. 2018; 13(11): e0206823. Published online 2018 Nov 12. doi: 10.1371/journal.pone.0206823

PMCID:: PMC6231638

Abstract Article PDF–3.8M

Select item 61395198.

Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease

Kevin R. Kipp, Samantha L. Kruger, Margaret F. Schimmel, Nikki Parker, Jonathan M. Shillingford, Christopher P. Leamon, Thomas Weimbs

Am J Physiol Renal Physiol. 2018 Aug 1; 315(2): F395–F405. Published online 2018 May 2. doi: 10.1152/ajprenal.00057.2018

PMCID:: PMC6139519

Abstract Article

Select item 60877909.

Identification of targets of IL-13 and STAT6 signaling in polycystic kidney disease

Erin E. Olsan, Jonathan D. West, Jacob A. Torres, Nicholas Doerr, Thomas Weimbs

Am J Physiol Renal Physiol. 2018 Jul 1; 315(1): F86–F96. Published online 2018 Mar 7. doi: 10.1152/ajprenal.00346.2017

PMCID:: PMC6087790

Abstract Article

Select item 605605910.

Role of Bicaudal C1 in renal gluconeogenesis and its novel interaction with the CTLH complex

Lucia Carolina Leal-Esteban, Benjamin Rothé, Simon Fortier, Manuela Isenschmid, Daniel B. Constam

PLoS Genet. 2018 Jul; 14(7): e1007487. Published online 2018 Jul 11. doi: 10.1371/journal.pgen.1007487

PMCID:: PMC6056059

Abstract Article PDF–8.9M

Select item 480417611.

Genetic link between renal birth defects and congenital heart disease

Jovenal T. San Agustin, Nikolai Klena, Kristi Granath, Ashok Panigrahy, Eileen Stewart, William Devine, Lara Strittmatter, Julie A. Jonassen, Xiaoqin Liu, Cecilia W. Lo, Gregory J. Pazour

Nat Commun. 2016; 7: 11103. Published online 2016 Mar 22. doi: 10.1038/ncomms11103

Correction in:: Nat Commun. 2016; 7: 11910.

PMCID:: PMC4804176

Abstract Article PDF–3.9M

Select item 480353212.

Role of β-catenin in development of bile ducts

Sabine Cordi, Cécile Godard, Thoueiba Saandi, Patrick Jacquemin, Satdarshan P. Monga, Sabine Colnot, Frédéric P. Lemaigre

Differentiation. Author manuscript; available in PMC 2017 Feb 5.

Published in final edited form as: Differentiation. 2016 Jan-Mar; 91(1-3): 42–49. Published online 2016 Feb 5. doi: 10.1016/j.diff.2016.02.001

PMCID:: PMC4803532

Abstract Article PDF–2.7M

Select item 461754013.

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo

Nature. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269

PMCID:: PMC4617540

Abstract Article PDF–518K

Select item 456173014.

Bicc1 Polymerization Regulates the Localization and Silencing of Bound mRNA

Benjamin Rothé, Lucia Leal-Esteban, Florian Bernet, Séverine Urfer, Nicholas Doerr, Thomas Weimbs, Justyna Iwaszkiewicz, Daniel B. Constam

Mol Cell Biol. 2015 Oct; 35(19): 3339–3353. Prepublished online 2015 Jul 27. Published online 2015 Sep 4. doi: 10.1128/MCB.00341-15

PMCID:: PMC4561730

Abstract Article PDF–4.8M

Select item 450547815.

Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease

Erin E. Olsan, Tamami Matsushita, Mina Rezaei, Thomas Weimbs

J Biol Chem. 2015 Jun 19; 290(25): 15679–15686. Published online 2015 Apr 28. doi: 10.1074/jbc.M114.607929

PMCID:: PMC4505478

Abstract Article PDF–1.6M

Select item 441626116.

Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression

Nathalie Piazzon, Florian Bernet, Linda Guihard, Wouter N Leonhard, Séverine Urfer, Dmitri Firsov, Hassib Chehade, Bruno Vogt, Sophia Piergiovanni, Dorien JM Peters, Olivier Bonny, Daniel B Constam

J Transl Med. 2015; 13: 103. Published online 2015 Mar 30. doi: 10.1186/s12967-015-0463-7

PMCID:: PMC4416261

Abstract Article PDF–1.2M

Select item 435298117.

Hnf1b controls pancreas morphogenesis and the generation of Ngn3⁺ endocrine progenitors

Matias G. De Vas, Janel L. Kopp, Claire Heliot, Maike Sander, Silvia Cereghini, Cécile Haumaitre

Development. 2015 Mar 1; 142(5): 871–882. doi: 10.1242/dev.110759

PMCID:: PMC4352981

Abstract Article

Select item 403857418.

Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density

Larry D. Mesner, Brianne Ray, Yi-Hsiang Hsu, Ani Manichaikul, Eric Lum, Elizabeth C. Bryda, Stephen S. Rich, Clifford J. Rosen, Michael H. Criqui, Matthew Allison, Matthew J. Budoff, Thomas L. Clemens, Charles R. Farber

J Clin Invest. 2014 Jun 2; 124(6): 2736–2749. Published online 2014 May 1. doi: 10.1172/JCI73072

PMCID:: PMC4038574

Abstract Article PDF–2.7M

Select item 394042319.

Loss of Polycystin-1 Inhibits Bicc1 Expression during Mouse Development

Peiwen Lian, Ao Li, Yuan Li, Haichao Liu, Dan Liang, Bo Hu, De Lin, Tang Jiang, Gilbert Moeckel, Dahui Qin, Guanqing Wu

PLoS One. 2014; 9(3): e88816. Published online 2014 Mar 3. doi: 10.1371/journal.pone.0088816

PMCID:: PMC3940423

Abstract Article PDF–2.1M

Select item 335854120.

ENU Mutagenesis in Mice Identifies Candidate Genes For Hypogonadism

Jeffrey Weiss, Lisa A. Hurley, Rebecca M. Harris, Courtney Finlayson, Minghan Tong, Lisa A. Fisher, Jennifer L. Moran, David R. Beier, Christopher Mason, J. Larry Jameson

Mamm Genome. Author manuscript; available in PMC 2013 Jun 1.

Published in final edited form as: Mamm Genome. 2012 Jun; 23(5-6): 346–355. Published online 2012 Jan 19. doi: 10.1007/s00335-011-9388-5

PMCID:: PMC3358541

Abstract Article PDF–2.7M

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