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Select item 112378701.

Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice

Christian Schmithals, Bianca Kakoschky, Dominic Denk, Maike von Harten, Jan Henrik Klug, Edith Hintermann, Anne Dropmann, Eman Hamza, Anne Claire Jacomin, Jens U. Marquardt, Stefan Zeuzem, Peter Schirmacher, Eva Herrmann, Urs Christen, Thomas J. Vogl, Oliver Waidmann, Steven Dooley, Fabian Finkelmeier, Albrecht Piiper

eBioMedicine. 2024 Jul; 105: 105178. Published online 2024 Jun 17. doi: 10.1016/j.ebiom.2024.105178

PMCID:: PMC11237870

Abstract Article PDF–2.2M

Select item 95882782.

Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice

Christopher M. Davenport, Brett J.W. Teubner, Seung Baek Han, Mary H. Patton, Tae-Yeon Eom, Dusan Garic, Benjamin J. Lansdell, Abbas Shirinifard, Ti-Cheng Chang, Jonathon Klein, Shondra M. Pruett-Miller, Jay A. Blundon, Stanislav S. Zakharenko

Cell. Author manuscript; available in PMC 2023 Oct 13.

Published in final edited form as: Cell. 2022 Oct 13; 185(21): 3877–3895.e21. Published online 2022 Sep 23. doi: 10.1016/j.cell.2022.08.022

PMCID:: PMC9588278

Abstract Article PDF–3.5M

Select item 75267913.

Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences

Nathan D Kopp, Kayla R Nygaard, Yating Liu, Katherine B McCullough, Susan E Maloney, Harrison W Gabel, Joseph D Dougherty

Hum Mol Genet. 2020 Jun 3; 29(9): 1498–1519. Published online 2020 Apr 21. doi: 10.1093/hmg/ddaa070

PMCID:: PMC7526791

Abstract Article PDF–3.9M

Select item 73430534.

Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models

Nathan Kopp, Katherine McCullough, Susan E Maloney, Joseph D Dougherty

Hum Mol Genet. 2019 Oct 15; 28(20): 3443–3465. Published online 2019 Aug 16. doi: 10.1093/hmg/ddz176

PMCID:: PMC7343053

Abstract Article PDF–8.7M

Select item 61405395.

Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma

Roland Sonntag, Nives Giebeler, Yulia A. Nevzorova, Jörg-Martin Bangen, Dirk Fahrenkamp, Daniela Lambertz, Ute Haas, Wei Hu, Nikolaus Gassler, Francisco Javier Cubero, Gerhard Müller-Newen, Ali T. Abdallah, Ralf Weiskirchen, Fabio Ticconi, Ivan G. Costa, Mariano Barbacid, Christian Trautwein, Christian Liedtke

Proc Natl Acad Sci U S A. 2018 Sep 11; 115(37): 9282–9287. Published online 2018 Aug 27. doi: 10.1073/pnas.1807155115

PMCID:: PMC6140539

Abstract Article PDF–1.4M

Select item 58140166.

Selective targeting of tumor associated macrophages in different tumor models

Bianca Kakoschky, Thomas Pleli, Christian Schmithals, Stefan Zeuzem, Bernhard Brüne, Thomas J. Vogl, Horst-Werner Korf, Andreas Weigert, Albrecht Piiper

PLoS One. 2018; 13(2): e0193015. Published online 2018 Feb 15. doi: 10.1371/journal.pone.0193015

PMCID:: PMC5814016

Abstract Article PDF–3.4M

Select item 57657557.

Repression of adipose tissue fibrosis through a PRDM16-GTF2IRD1 complex improves systemic glucose homeostasis

Yutaka Hasegawa, Kenji Ikeda, Yong Chen, Diana Alba, Daniel Stifler, Kosaku Shinoda, Takashi Hosono, Pema Maretich, Yangyu Yang, Yasushi Ishigaki, Jingyi Chi, Paul Cohen, Suneil Koliwad, Shingo Kajimura

Cell Metab. Author manuscript; available in PMC 2019 Jan 9.

Published in final edited form as: Cell Metab. 2018 Jan 9; 27(1): 180–194.e6. doi: 10.1016/j.cmet.2017.12.005

PMCID:: PMC5765755

Abstract Article PDF–3.0M

Select item 54120788.

An in vivo gain-of-function screen identifies the Williams-Beuren Syndrome gene GTF2IRD1 as a mammary tumor promoter

Yongliang Huo, Timothy Su, Qiuyin Cai, Ian G. Macara

Cell Rep. Author manuscript; available in PMC 2017 May 2.

Published in final edited form as: Cell Rep. 2016 Jun 7; 15(10): 2089–2096. Published online 2016 May 26. doi: 10.1016/j.celrep.2016.05.011

PMCID:: PMC5412078

Abstract Article PDF–1.8M

Select item 49070169.

RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome

Susan M. Corley, Cesar P. Canales, Paulina Carmona-Mora, Veronica Mendoza-Reinosa, Annemiek Beverdam, Edna C. Hardeman, Marc R. Wilkins, Stephen J. Palmer

BMC Genomics. 2016; 17: 450. Published online 2016 Jun 13. doi: 10.1186/s12864-016-2801-4

PMCID:: PMC4907016

Abstract Article PDF–2.0M

Select item 483627110.

Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon

Tomohiro Kayama, Masaki Mori, Yoshiaki Ito, Takahide Matsushima, Ryo Nakamichi, Hidetsugu Suzuki, Shizuko Ichinose, Mitsuru Saito, Keishi Marumo, Hiroshi Asahara

Mol Cell Biol. 2016 Apr 15; 36(8): 1297–1309. Prepublished online 2016 Feb 16. Published online 2016 Apr 1. doi: 10.1128/MCB.00950-15

PMCID:: PMC4836271

Abstract Article PDF–1.6M

Select item 479505911.

The role of GTF2IRD1 in the auditory pathology of Williams–Beuren Syndrome

Cesar P Canales, Ann C Y Wong, Peter W Gunning, Gary D Housley, Edna C Hardeman, Stephen J Palmer

Eur J Hum Genet. 2015 Jun; 23(6): 774–780. Published online 2014 Sep 24. doi: 10.1038/ejhg.2014.188

PMCID:: PMC4795059

Abstract Article PDF–2.0M

Select item 430975112.

Astrocyte elevated gene-1 (AEG-1) and c-Myc cooperate to promote hepatocarcinogenesis

Jyoti Srivastava, Ayesha Siddiq, Rachel Gredler, Xue-Ning Shen, Devaraja Rajasekaran, Chadia L. Robertson, Mark A. Subler, Jolene J. Windle, Catherine I. Dumur, Nitai D. Mukhopadhyay, Dawn Garcia, Zhao Lai, Yidong Chen, Uthra Balaji, Paul B. Fisher, Devanand Sarkar

Hepatology. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: Hepatology. 2015 Mar; 61(3): 915–929. Published online 2015 Jan 23. doi: 10.1002/hep.27339

PMCID:: PMC4309751

Abstract Article PDF–1.7M

Select item 422813813.

The Transcription Factor GTF2IRD1 Regulates the Topology and Function of Photoreceptors by Modulating Photoreceptor Gene Expression across the Retina

Tomohiro Masuda, Xiaodong Zhang, Cindy Berlinicke, Jun Wan, Anitha Yerrabelli, Elizabeth A. Conner, Sten Kjellstrom, Ronald Bush, Snorri S. Thorgeirsson, Anand Swaroop, Shiming Chen, Donald J. Zack

J Neurosci. 2014 Nov 12; 34(46): 15356–15368. doi: 10.1523/JNEUROSCI.2089-14.2014

PMCID:: PMC4228138

Abstract Article PDF–3.6M

Select item 353339014.

GTF2IRD2 from the Williams–Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members

Stephen J. Palmer, Kylie M. Taylor, Nicole Santucci, Jocelyn Widagdo, Yee-Ka Agnes Chan, Jen-Li Yeo, Merritt Adams, Peter W. Gunning, Edna C. Hardeman

J Cell Sci. 2012 Nov 1; 125(21): 5040–5050. doi: 10.1242/jcs.102798

PMCID:: PMC3533390

Abstract Article

Select item 343984515.

A Genome-Wide Screen to Identify Transcription Factors Expressed in Pelvic Ganglia of the Lower Urinary Tract

Carrie B. Wiese, Sara Ireland, Nicole L. Fleming, Jing Yu, M. Todd Valerius, Kylie Georgas, Han Sheng Chiu, Jane Brennan, Jane Armstrong, Melissa H. Little, Andrew P. McMahon, E. Michelle Southard-Smith

Front Neurosci. 2012; 6: 130. Published online 2012 Sep 12. doi: 10.3389/fnins.2012.00130

PMCID:: PMC3439845

Abstract Article PDF–1.4M

Select item 337027016.

Duplication of GTF2I Results in Separation Anxiety in Mice and Humans

Carolyn B. Mervis, Joana Dida, Emily Lam, Nicole A. Crawford-Zelli, Edwin J. Young, Danielle R. Henderson, Tuncer Onay, Colleen A. Morris, Janet Woodruff-Borden, John Yeomans, Lucy R. Osborne

Am J Hum Genet. 2012 Jun 8; 90(6): 1064–1070. doi: 10.1016/j.ajhg.2012.04.012

PMCID:: PMC3370270

Abstract Article PDF–295K

Select item 322864417.

Intracellular Signaling and Hepatocellular Carcinoma

Polina Iakova, Lubov Timchenko, Nikolai A. Timchenko

Semin Cancer Biol. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: Semin Cancer Biol. 2011 Feb; 21(1): 28–34. Published online 2010 Sep 17. doi: 10.1016/j.semcancer.2010.09.001

PMCID:: PMC3228644

Abstract Article PDF–359K

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316612919.

Global Analysis of Gene Expression in the Developing Brain of Gtf2ird1 Knockout Mice

Jennifer O'Leary, Lucy R. Osborne

PLoS One. 2011; 6(8): e23868. Published online 2011 Aug 31. doi: 10.1371/journal.pone.0023868

PMCID:: PMC3166129

Abstract Article PDF–436K

Select item 311015120.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Abstract Article PDF–2.0M

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