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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 77529492.

Tryptophan 2,3-Dioxygenase Expression Identified in Murine Decidual Stromal Cells Is Not Essential for Feto-Maternal Tolerance

Delia Hoffmann, Tereza Dvorakova, Florence Schramme, Vincent Stroobant, Benoit J. Van den Eynde

Front Immunol. 2020; 11: 601759. Published online 2020 Dec 8. doi: 10.3389/fimmu.2020.601759

PMCID:: PMC7752949

Abstract Article PDF–6.1M

Select item 72922713.

Comprehensive behavioral analysis of tryptophan 2,3‐dioxygenase (Tdo2) knockout mice

Satoko Hattori, Keizo Takao, Hiroshi Funakoshi, Tsuyoshi Miyakawa

Neuropsychopharmacol Rep. 2018 Jun; 38(2): 52–60. Published online 2018 Mar 15. doi: 10.1002/npr2.12006

PMCID:: PMC7292271

Abstract Article PDF–439K

Select item 63984474.

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto

Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146

PMCID:: PMC6398447

Abstract Article

Select item 58084605.

Tryptophan 2,3-Dioxygenfase and Indoleamine 2,3-Dioxygenase 1 Make Separate, Tissue-Specific Contributions to Basal and Inflammation-Induced Kynurenine Pathway Metabolism in Mice

Paul B. Larkin, Korrapati V. Sathyasaikumar, Francesca M. Notarangelo, Hiroshi Funakoshi, Toshikazu Nakamura, Robert Schwarcz, Paul J. Muchowski

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Feb 12.

Published in final edited form as: Biochim Biophys Acta. 2016 Nov; 1860(11 Pt A): 2345–2354. Published online 2016 Jul 5. doi: 10.1016/j.bbagen.2016.07.002

PMCID:: PMC5808460

Abstract Article PDF–873K

Select item 55221926.

Indoleamine 2,3-dioxygenase 1 deficiency attenuates CCl₄-induced fibrosis through Th17 cells down-regulation and tryptophan 2,3-dioxygenase compensation

Weichao Zhong, Lei Gao, Zhenting Zhou, Haiyan Lin, Chun Chen, Peng Huang, Weiliang Huang, Chuying Zhou, Shaohui Huang, Linghui Nie, Ye Liu, Youming Chen, Daqiao Zhou, Zhiping Lv

Oncotarget. 2017 Jun 20; 8(25): 40486–40500. Published online 2017 Apr 15. doi: 10.18632/oncotarget.17119

PMCID:: PMC5522192

Abstract Article PDF–10M

Select item 54213567.

Hypertryptophanemia due to tryptophan 2,3-dioxygenase deficiency

Patrick Ferreira, Inchul Shin, Iveta Sosova, Kednerlin Dornevil, Shailly Jain, Deborah Dewey, Fange Liu, Aimin Liu

Mol Genet Metab. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Mol Genet Metab. 2017 Apr; 120(4): 317–324. Published online 2017 Mar 1. doi: 10.1016/j.ymgme.2017.02.009

PMCID:: PMC5421356

Abstract Article PDF–1.1M

Select item 52597668.

Tryptophan-2,3-Dioxygenase (TDO) deficiency is associated with subclinical neuroprotection in a mouse model of multiple sclerosis

Tobias V. Lanz, Sarah K. Williams, Aleksandar Stojic, Simeon Iwantscheff, Jana K. Sonner, Carl Grabitz, Simon Becker, Laura-Inés Böhler, Soumya R. Mohapatra, Felix Sahm, Günter Küblbeck, Toshikazu Nakamura, Hiroshi Funakoshi, Christiane A. Opitz, Wolfgang Wick, Ricarda Diem, Michael Platten

Sci Rep. 2017; 7: 41271. Published online 2017 Jan 24. doi: 10.1038/srep41271

PMCID:: PMC5259766

Abstract Article PDF–2.0M

Select item 44843929.

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders

Heather Fairfield, Anuj Srivastava, Guruprasad Ananda, Rangjiao Liu, Martin Kircher, Anuradha Lakshminarayana, Belinda S. Harris, Son Yong Karst, Louise A. Dionne, Coleen C. Kane, Michelle Curtain, Melissa L. Berry, Patricia F. Ward-Bailey, Ian Greenstein, Candice Byers, Anne Czechanski, Jocelyn Sharp, Kristina Palmer, Polyxeni Gudis, Whitney Martin, Abby Tadenev, Laurent Bogdanik, C. Herbert Pratt, Bo Chang, David G. Schroeder, Gregory A. Cox, Paul Cliften, Jeffrey Milbrandt, Stephen Murray, Robert Burgess, David E. Bergstrom, Leah Rae Donahue, Hanan Hamamy, Amira Masri, Federico A. Santoni, Periklis Makrythanasis, Stylianos E. Antonarakis, Jay Shendure, Laura G. Reinholdt

Genome Res. 2015 Jul; 25(7): 948–957. doi: 10.1101/gr.186882.114

PMCID:: PMC4484392

Abstract Article PDF–604K

Select item 409807610.

Aryl hydrocarbon receptor control of a disease tolerance defense pathway

Alban Bessede, Marco Gargaro, Maria T Pallotta, Davide Matino, Giuseppe Servillo, Cinzia Brunacci, Silvio Bicciato, Emilia MC Mazza, Antonio Macchiarulo, Carmine Vacca, Rossana Iannitti, Luciana Tissi, Claudia Volpi, Maria L Belladonna, Ciriana Orabona, Roberta Bianchi, Tobias Lanz, Michael Platten, Maria A Della Fazia, Danilo Piobbico, Teresa Zelante, Hiroshi Funakoshi, Toshikazu Nakamura, David Gilot, Michael S Denison, Gilles J Guillemin, James B DuHadaway, George C Prendergast, Richard Metz, Michel Geffard, Louis Boon, Matteo Pirro, Alfonso Iorio, Bernard Veyret, Luigina Romani, Ursula Grohmann, Francesca Fallarino, Paolo Puccetti

Nature. Author manuscript; available in PMC 2015 Feb 10.

Published in final edited form as: Nature. 2014 Jul 10; 511(7508): 184–190. doi: 10.1038/nature13323

PMCID:: PMC4098076

Abstract Article PDF–1.3M

Select item 396495511.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 328931912.

Reversal of tumoral immune resistance by inhibition of tryptophan 2,3-dioxygenase

Luc Pilotte, Pierre Larrieu, Vincent Stroobant, Didier Colau, Eduard Dolušić, Raphaël Frédérick, Etienne De Plaen, Catherine Uyttenhove, Johan Wouters, Bernard Masereel, Benoît J. Van den Eynde

Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7): 2497–2502. Published online 2012 Jan 30. doi: 10.1073/pnas.1113873109

PMCID:: PMC3289319

Abstract Article PDF–775K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302320514.

Regulation of tryptophan 2,3-dioxygenase by HOXA10 enhances embryo viability through serotonin signaling

Leo F. Doherty, Hye Eun Kwon, Hugh S. Taylor

Am J Physiol Endocrinol Metab. 2011 Jan; 300(1): E86–E93. Published online 2010 Oct 19. doi: 10.1152/ajpendo.00439.2010

PMCID:: PMC3023205

Abstract Article

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 294533716.

Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus

Koji Ohira,, Hideo Hagihara,, Keiko Toyama,, Keizo Takao, Masaaki Kanai, Hiroshi Funakoshi, Toshikazu Nakamura, Tsuyoshi Miyakawa

Mol Brain. 2010; 3: 26. Published online 2010 Sep 5. doi: 10.1186/1756-6606-3-26

PMCID:: PMC2945337

Abstract Article PDF–2.7M

Select item 267321717.

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

Masaaki Kanai, Hiroshi Funakoshi, Hisaaki Takahashi, Tomoko Hayakawa, Shinya Mizuno, Kunio Matsumoto, Toshikazu Nakamura

Mol Brain. 2009; 2: 8. Published online 2009 Mar 27. doi: 10.1186/1756-6606-2-8

PMCID:: PMC2673217

Abstract Article PDF–2.4M

Select item 155028318.

Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight

Anatole Ghazalpour, Sudheer Doss, Bin Zhang, Susanna Wang, Christopher Plaisier, Ruth Castellanos, Alec Brozell, Eric E Schadt, Thomas A Drake, Aldons J Lusis, Steve Horvath

PLoS Genet. 2006 Aug; 2(8): e130. Prepublished online 2006 Jun 30. Published online 2006 Aug 18. doi: 10.1371/journal.pgen.0020130

PMCID:: PMC1550283

Abstract Article PDF–416K

Select item 117129719.

Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer.

A Kamiya, T Kinoshita, Y Ito, T Matsui, Y Morikawa, E Senba, K Nakashima, T Taga, K Yoshida, T Kishimoto, A Miyajima

EMBO J. 1999 Apr 15; 18(8): 2127–2136. doi: 10.1093/emboj/18.8.2127

PMCID:: PMC1171297

Summary PDF–498K

Select item 31099220.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

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