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Items: 1 to 20 of 32

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
WDR62-deficiency Causes Autism-like Behaviors Independent of Microcephaly in Mice
Dan Xu, Yiqiang Zhi, Xinyi Liu, Le Guan, Jurui Yu, Dan Zhang, Weiya Zhang, Yaqing Wang, Wucheng Tao, Zhiheng Xu
Neurosci Bull. 2023 Sep; 39(9): 1333–1347. Published online 2022 Dec 26. doi: 10.1007/s12264-022-00997-5
PMCID:
PMC10465473
AbstractArticlePDF–11M
3.
Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
Hamid Meziane, Marie-Christine Birling, Olivia Wendling, Sophie Leblanc, Aline Dubos, Mohammed Selloum, Guillaume Pavlovic, Tania Sorg, Vera M. Kalscheuer, Pierre Billuart, Frédéric Laumonnier, Jamel Chelly, Hans van Bokhoven, Yann Herault
Biomedicines. 2022 Dec; 10(12): 3148. Published online 2022 Dec 6. doi: 10.3390/biomedicines10123148
PMCID:
PMC9775489
AbstractArticlePDF–2.8M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
Uda Y. Ho, Chun-Wei Allen Feng, Yvonne Y. Yeap, Amanda L. Bain, Zhe Wei, Belal Shohayeb, Melissa E. Reichelt, Hayden Homer, Kum Kum Khanna, Josephine Bowles, Dominic C. H. Ng
Commun Biol. 2021; 4: 645. Published online 2021 May 31. doi: 10.1038/s42003-021-02171-5
PMCID:
PMC8167107
AbstractArticlePDF–7.0M
6.
The Spindle-Associated Microcephaly Protein, WDR62, Is Required for Neurogenesis and Development of the Hippocampus
Belal Shohayeb, Uda Y. Ho, Halah Hassan, Michael Piper, Dominic C. H. Ng
Front Cell Dev Biol. 2020; 8: 549353. Published online 2020 Sep 11. doi: 10.3389/fcell.2020.549353
PMCID:
PMC7517699
AbstractArticlePDF–8.0M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors
Wei Zhang, Si-Lu Yang, Mei Yang, Stephanie Herrlinger, Qiang Shao, John L. Collar, Edgar Fierro, Yanhong Shi, Aimin Liu, Hui Lu, Bruce E. Herring, Ming-Lei Guo, Shilpa Buch, Zhen Zhao, Jian Xu, Zhipeng Lu, Jian-Fu Chen
Nat Commun. 2019; 10: 2612. Published online 2019 Jun 13. doi: 10.1038/s41467-019-10497-2
PMCID:
PMC6565620
AbstractArticlePDF–6.1M
9.
MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis
Dan Xu, Minghui Yao, Yaqing Wang, Ling Yuan, Joerg D. Hoeck, Jingwen Yu, Liang Liu, Yvonne Y. C. Yeap, Weiya Zhang, Feng Zhang, Yinghang Feng, Tiantian Ma, Yujie Wang, Dominic C. H. Ng, Xiaoyin Niu, Bing Su, Axel Behrens, Zhiheng Xu
PLoS Biol. 2018 Dec; 16(12): e2006613. Published online 2018 Dec 19. doi: 10.1371/journal.pbio.2006613
PMCID:
PMC6347294
AbstractArticlePDF–3.5M
10.
Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans
Yang Zhou, Yan Qin, Yingying Qin, Binyang Xu, Ting Guo, Hanni Ke, Min Chen, Lianjun Zhang, Feng Han, Yaqiong Li, Min Chen, Axel Behrens, Yaqing Wang, Zhiheng Xu, Zi-Jiang Chen, Fei Gao
PLoS Genet. 2018 Aug; 14(8): e1007463. Published online 2018 Aug 13. doi: 10.1371/journal.pgen.1007463
Correction in:
PLoS Genet. 2019 Nov; 15(11): e1008504.
PMCID:
PMC6107287
AbstractArticlePDF–13M
11.
WDR62 is associated with the spindle pole and is mutated in human microcephaly
Adeline K Nicholas, Maryam Khurshid, Julie Désir, Ofélia P Carvalho, James J Cox, Gemma Thornton, Rizwana Kausar, Muhammad Ansar, Wasim Ahmad, Alain Verloes, Sandrine Passemard, Jean-Paul Misson, Susan Lindsay, Fanni Gergely, William B Dobyns, Emma Roberts, Marc Abramowicz, C Geoffrey Woods
Nat Genet. Author manuscript; available in PMC 2017 Sep 19.
Published in final edited form as: Nat Genet. 2010 Nov; 42(11): 1010–1014. Published online 2010 Oct 3. doi: 10.1038/ng.682
PMCID:
PMC5605390
AbstractArticlePDF–961K
12.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
13.
Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly
Paraskevi Sgourdou, Ketu Mishra-Gorur, Ichiko Saotome, Octavian Henagariu, Beyhan Tuysuz, Cynthia Campos, Keiko Ishigame, Krinio Giannikou, Jennifer L. Quon, Nenad Sestan, Ahmet O. Caglayan, Murat Gunel, Angeliki Louvi
Sci Rep. 2017; 7: 43708. Published online 2017 Mar 8. doi: 10.1038/srep43708
PMCID:
PMC5341122
AbstractArticlePDF–3.4M
14.
Microcephaly proteins Wdr62 and Aspm define a mother centriole complex regulating centriole biogenesis, apical complex and cell fate
Divya Jayaraman, Andrew Kodani, Dilenny M. Gonzalez, Joseph D. Mancias, Ganeshwaran H. Mochida, Cristiana Vagnoni, Jeffrey Johnson, Nevan Krogan, J. Wade Harper, Jeremy F. Reiter, Timothy W. Yu, Byoung-il Bae, Christopher A. Walsh
Neuron. Author manuscript; available in PMC 2017 Nov 23.
Published in final edited form as: Neuron. 2016 Nov 23; 92(4): 813–828. Published online 2016 Oct 27. doi: 10.1016/j.neuron.2016.09.056
PMCID:
PMC5199216
AbstractArticlePDF–3.5M
15.
A Novel c-Jun N-terminal Kinase (JNK) Signaling Complex Involved in Neuronal Migration during Brain Development
Feng Zhang, Jingwen Yu, Tao Yang, Dan Xu, Zhixia Chi, Yanheng Xia, Zhiheng Xu
J Biol Chem. 2016 May 27; 291(22): 11466–11475. Published online 2016 Mar 29. doi: 10.1074/jbc.M116.716811
PMCID:
PMC4882418
AbstractArticlePDF–4.3M
16.
Global genetic analysis in mice unveils central role for cilia in congenital heart disease
You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo
Nature. Author manuscript; available in PMC 2015 Nov 28.
Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269
PMCID:
PMC4617540
AbstractArticlePDF–518K
17.
Microcephaly Disease Gene Wdr62 Regulates Mitotic Progression of Embryonic Neural Stem Cells and Brain Size
Jian-Fu Chen, Ying Zhang, Jonathan Wilde, Kirk Hansen, Fan Lai, Lee Niswander
Nat Commun. Author manuscript; available in PMC 2014 Nov 30.
Published in final edited form as: Nat Commun. 2014; 5: 3885. Published online 2014 May 30. doi: 10.1038/ncomms4885
PMCID:
PMC4216695
AbstractArticlePDF–2.2M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression
Marie A. Bogoyevitch, Yvonne Y. C. Yeap, Zhengdong Qu, Kevin R. Ngoei, Yan Y. Yip, Teresa T. Zhao, Julian I. Heng, Dominic C. H. Ng
J Cell Sci. 2012 Nov 1; 125(21): 5096–5109. doi: 10.1242/jcs.107326
PMCID:
PMC3533392
AbstractArticle
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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