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Items: 1 to 20 of 41

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Biphasic expression of thyroid hormone receptor TRβ1 in mammalian retina and anterior ocular tissues
Lily Ng, Hong Liu, Ye Liu, Douglas Forrest
Front Endocrinol (Lausanne) 2023; 14: 1174600. Published online 2023 Mar 23. doi: 10.3389/fendo.2023.1174600
PMCID:
PMC10076699
AbstractArticlePDF–17M
3.
FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells
Matthew R. Jones, Arun Lingampally, Negah Ahmadvand, Lei Chong, Jin Wu, Jochen Wilhem, Ana Ivonne Vazquez-Armendariz, Meshal Ansari, Susanne Herold, David M. Ornitz, Herbert B. Schiller, Cho-Ming Chao, Jin-San Zhang, Gianni Carraro, Saverio Bellusci
Cell Mol Life Sci. 2022; 79(12): 609. Published online 2022 Nov 29. doi: 10.1007/s00018-022-04626-2
PMCID:
PMC9708820
AbstractArticlePDF–3.1M
4.
Hypochlorhydria reduces mortality in heart failure caused by Kcne2 gene deletion
Ulrike Lisewski, Clemens Köhncke, Leonhard Schleussner, Bettina Purfürst, Soo Min Lee, Angele De Silva, Rían W. Manville, Geoffrey W. Abbott, Torsten K. Roepke
FASEB J. Author manuscript; available in PMC 2021 Dec 2.
Published in final edited form as: FASEB J. 2020 Aug; 34(8): 10699–10719. Published online 2020 Jun 25. doi: 10.1096/fj.202000013RR
PMCID:
PMC8638375
AbstractArticlePDF–3.4M
5.
Expression and Localization of Kcne2 in the Vertebrate Retina
Moritz Lindner, Michael J. Gilhooley, Teele Palumaa, A. Jennifer Morton, Steven Hughes, Mark W. Hankins
Invest Ophthalmol Vis Sci. 2020 Mar; 61(3): 33. Published online 2020 Mar 19. doi: 10.1167/iovs.61.3.33
PMCID:
PMC7401445
AbstractArticlePDF–1.9M
6.
The KCNE2 potassium channel β subunit is required for normal lung function and resilience to ischemia and reperfusion injury
Leng Zhou, Clemens Köhncke, Zhaoyang Hu, Torsten K. Roepke, Geoffrey W. Abbott
FASEB J. 2019 Sep; 33(9): 9762–9774. Published online 2019 Jun 4. doi: 10.1096/fj.201802519R
PMCID:
PMC6704464
AbstractArticle
7.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
8.
AKT and ERK1/2 activation via remote ischemic preconditioning prevents Kcne2‐dependent sudden cardiac death
Zhaoyang Hu, Jin Liu, Leng Zhou, Xin Tian, Geoffrey W. Abbott
Physiol Rep. 2019 Feb; 7(3): e13957. Published online 2019 Feb 8. doi: 10.14814/phy2.13957
PMCID:
PMC6368489
AbstractArticlePDF–3.0M
9.
Single-cell transcriptomic analysis of mouse neocortical development
Lipin Loo, Jeremy M. Simon, Lei Xing, Eric S. McCoy, Jesse K. Niehaus, Jiami Guo, E. S. Anton, Mark J. Zylka
Nat Commun. 2019; 10: 134. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08079-9
PMCID:
PMC6329831
AbstractArticlePDF–3.6M
10.
Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus
Jennifer Larimore, Stephanie A. Zlatic, Miranda Arnold, Kaela S. Singleton, Rebecca Cross, Hannah Rudolph, Martha V. Bruegge, Andrea Sweetman, Cecilia Garza, Eli Whisnant, Victor Faundez
Front Genet. 2017; 8: 28. Published online 2017 Mar 10. doi: 10.3389/fgene.2017.00028
PMCID:
PMC5344932
AbstractArticlePDF–4.0M
11.
Kcne2 Deletion Creates a Multisystem Syndrome Predisposing to Sudden Cardiac Death
Zhaoyang Hu, Ritu Kant, Marie Anand, Elizabeth C. King, Trine Krogh-Madsen, David J. Christini, Geoffrey W. Abbott
Circ Cardiovasc Genet. Author manuscript; available in PMC 2016 Jun 22.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Feb; 7(1): 33–42. Published online 2014 Jan 8. doi: 10.1161/CIRCGENETICS.113.000315
PMCID:
PMC4917016
AbstractArticlePDF–2.6M
12.
The KCNE2 K+ channel regulatory subunit: ubiquitous influence, complex pathobiology
Geoffrey W. Abbott
Gene. Author manuscript; available in PMC 2016 Sep 15.
Published in final edited form as: Gene. 2015 Sep 15; 569(2): 162–172. Published online 2015 Jun 27. doi: 10.1016/j.gene.2015.06.061
PMCID:
PMC4917011
AbstractArticlePDF–1.2M
13.
Kcne2 deletion attenuates acute post-ischaemia/reperfusion myocardial infarction
Zhaoyang Hu, Shawn M. Crump, Ping Zhang, Geoffrey W. Abbott
Cardiovasc Res. 2016 May 15; 110(2): 227–237. Published online 2016 Mar 6. doi: 10.1093/cvr/cvw048
PMCID:
PMC4836628
AbstractArticlePDF–1016K
14.
Kcne2 deletion causes early-onset nonalcoholic fatty liver disease via iron deficiency anemia
Soo Min Lee, Dara Nguyen, Marie Anand, Ritu Kant, Clemens Köhncke, Ulrike Lisewski, Torsten K. Roepke, Zhaoyang Hu, Geoffrey W. Abbott
Sci Rep. 2016; 6: 23118. Published online 2016 Mar 17. doi: 10.1038/srep23118
PMCID:
PMC4794722
AbstractArticlePDF–2.3M
15.
Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia
Grace Salsbury, Emma L. Cambridge, Zoe McIntyre, Mark J. Arends, Natasha A. Karp, Christopher Isherwood, Carl Shannon, Yvette Hooks, The Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, David J. Adams, Jacqueline K. White, Anneliese O. Speak
Exp Hematol. 2014 Dec; 42(12): 1053–1058.e1. doi: 10.1016/j.exphem.2014.07.269
Correction in:
Exp Hematol. 2015 May; 43(5): 424.
PMCID:
PMC4271779
AbstractArticlePDF–987K
16.
KCNQ1, KCNE2, and Na+-Coupled Solute Transporters Form Reciprocally Regulating Complexes that Affect Neuronal Excitability
Geoffrey W. Abbott, Kwok-Keung Tai, Daniel Neverisky, Alex Hansler, Zhaoyang Hu, Torsten K. Roepke, Daniel J. Lerner, Qiuying Chen, Li Liu, Bojana Zupan, Miklos Toth, Robin Haynes, Xiaoping Huang, Didem Demirbas, Roberto Buccafusca, Steven S. Gross, Vikram A. Kanda, Gerard T. Berry
Sci Signal. Author manuscript; available in PMC 2014 Jun 19.
Published in final edited form as: Sci Signal. 2014 Mar 4; 7(315): ra22. Published online 2014 Mar 4. doi: 10.1126/scisignal.2005025
PMCID:
PMC4063528
AbstractArticlePDF–1.3M
17.
Non-trisomic Homeobox Gene Expression during Craniofacial Development in the Ts65Dn Mouse Model of Down Syndrome
Cherie N. Billingsley, Jared R. Allen, Douglas D. Baumann, Samantha L. Deitz, Joshua D. Blazek, Abby Newbauer, Andrew Darrah, Brad C. Long, Brandon Young, Mark Clement, R.W. Doerge, Randall J. Roper
Am J Med Genet A. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Am J Med Genet A. 2013 Aug; 161(8): 1866–1874. Published online 2013 Jul 10. doi: 10.1002/ajmg.a.36006
PMCID:
PMC3729611
AbstractArticlePDF–319K
18.
BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels
Carolyn C. Sachse, Young Hye Kim, Marianne Agsten, Tobias Huth, Christian Alzheimer, Dora M. Kovacs, Doo Yeon Kim
FASEB J. 2013 Jun; 27(6): 2458–2467. doi: 10.1096/fj.12-214056
PMCID:
PMC3659364
AbstractArticle
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration
Stephen Lumayag, Caroline E. Haldin, Nicola J. Corbett, Karl J. Wahlin, Colleen Cowan, Sanja Turturro, Peter E. Larsen, Beatrix Kovacs, P. Dane Witmer, David Valle, Donald J. Zack, Daniel A. Nicholson, Shunbin Xu
Proc Natl Acad Sci U S A. 2013 Feb 5; 110(6): E507–E516. Published online 2013 Jan 22. doi: 10.1073/pnas.1212655110
PMCID:
PMC3568372
AbstractArticlePDF–2.1M

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