PMC Links for GEO Profiles (Select 53087965) - PMC

Select item 113906201.

Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons

Pedro Rifes, Janko Kajtez, Josefine Rågård Christiansen, Alrik Schörling, Gaurav Singh Rathore, Daniel A. Wolf, Andreas Heuer, Agnete Kirkeby

Stem Cell Reports. 2024 Jun 11; 19(6): 830–838. Published online 2024 May 16. doi: 10.1016/j.stemcr.2024.04.010

PMCID:: PMC11390620

Abstract Article PDF–15M

Select item 98491412.

A proteome-scale map of the SARS-CoV-2–human contactome

Dae-Kyum Kim, Benjamin Weller, Chung-Wen Lin, Dayag Sheykhkarimli, Jennifer J. Knapp, Guillaume Dugied, Andreas Zanzoni, Carles Pons, Marie J. Tofaute, Sibusiso B. Maseko, Kerstin Spirohn, Florent Laval, Luke Lambourne, Nishka Kishore, Ashyad Rayhan, Mayra Sauer, Veronika Young, Hridi Halder, Nora Marín-de la Rosa, Oxana Pogoutse, Alexandra Strobel, Patrick Schwehn, Roujia Li, Simin T. Rothballer, Melina Altmann, Patricia Cassonnet, Atina G. Coté, Lena Elorduy Vergara, Isaiah Hazelwood, Betty B. Liu, Maria Nguyen, Ramakrishnan Pandiarajan, Bushra Dohai, Patricia A. Rodriguez Coloma, Juline Poirson, Paolo Giuliana, Luc Willems, Mikko Taipale, Yves Jacob, Tong Hao, David E. Hill, Christine Brun, Jean-Claude Twizere, Daniel Krappmann, Matthias Heinig, Claudia Falter, Patrick Aloy, Caroline Demeret, Marc Vidal, Michael A. Calderwood, Frederick P. Roth, Pascal Falter-Braun

Nat Biotechnol. 2023; 41(1): 140–149. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01475-z

PMCID:: PMC9849141

Abstract Article PDF–7.1M

Select item 80090483.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 74329194.

Epigenetic Silencing of LMX1A Contributes to Cancer Progression in Lung Cancer Cells

Ti-Hui Wu, Shan-Yueh Chang, Yu-Lueng Shih, Chih-Feng Chian, Hung Chang, Ya-Wen Lin

Int J Mol Sci. 2020 Aug; 21(15): 5425. Published online 2020 Jul 30. doi: 10.3390/ijms21155425

PMCID:: PMC7432919

Abstract Article PDF–3.4M

Select item 70936945.

Circular RNA circMTO1 Suppresses RCC Cancer Cell Progression via miR9/LMX1A Axis

Kecheng Li, Cheng-Liang Wan, Yan Guo

Technol Cancer Res Treat. 2020; 19: 1533033820914286. Published online 2020 Mar 24. doi: 10.1177/1533033820914286

PMCID:: PMC7093694

Abstract Article PDF–568K

Select item 69329336.

LINC00682 inhibits gastric cancer cell progression via targeting microRNA-9-LMX1A signaling axis

Xiaohong Zhang, Jian Li, Fan Li, Zhen Zhao, Li Feng

Aging (Albany NY) 2019 Dec 15; 11(23): 11358–11368. Published online 2019 Dec 11. doi: 10.18632/aging.102533

PMCID:: PMC6932933

Abstract Article PDF–1.5M

Select item 67620617.

LMX1A inhibits C-Myc expression through ANGPTL4 to exert tumor suppressive role in gastric cancer

Peiyu Qian, Jian Li, Xiaohong Zhang, Fan Li, Songhua Bei, Huanqing Li, Qi Sun, Li Feng

PLoS One. 2019; 14(9): e0221640. Published online 2019 Sep 26. doi: 10.1371/journal.pone.0221640

PMCID:: PMC6762061

Abstract Article PDF–1.2M

Select item 66535558.

Knockdown of LncRNA SCAMP1 suppressed malignant biological behaviours of glioma cells via modulating miR‐499a‐5p/LMX1A/NLRC5 pathway

Zheqi Zong, Yichen Song, Yixue Xue, Xuelei Ruan, Xiaobai Liu, Chunqing Yang, Jian Zheng, Shuo Cao, Zhen Li, Yunhui Liu

J Cell Mol Med. 2019 Aug; 23(8): 5048–5062. Published online 2019 Jun 17. doi: 10.1111/jcmm.14362

PMCID:: PMC6653555

Abstract Article PDF–3.5M

Select item 60949409.

A variant in LMX1A causes autosomal recessive severe-to-profound hearing impairment

Isabelle Schrauwen, Imen Chakchouk, Khurram Liaqat, Abid Jan, Abdul Nasir, Shabir Hussain, Deborah A. Nickerson, Michael J. Bamshad, Asmat Ullah, Wasim Ahmad, Suzanne M. Leal

Hum Genet. Author manuscript; available in PMC 2018 Aug 16.

Published in final edited form as: Hum Genet. 2018 Jul; 137(6-7): 471–478. Published online 2018 Jul 3. doi: 10.1007/s00439-018-1899-7

PMCID:: PMC6094940

Abstract Article PDF–764K

Select item 597395910.

Heterozygous missense variants of LMX1A lead to nonsyndromic hearing impairment and vestibular dysfunction

Mieke Wesdorp, Pia A. M. de Koning Gans, Margit Schraders, Jaap Oostrik, Martijn A. Huynen, Hanka Venselaar, Andy J. Beynon, Judith van Gaalen, Vitória Piai, Nicol Voermans, Michelle M. van Rossum, Bas P. Hartel, Stefan H. Lelieveld, Laurens Wiel, Berit Verbist, Liselotte J. Rotteveel, Marieke F. van Dooren, Peter Lichtner, Henricus P. M. Kunst, Ilse Feenstra, Ronald J. C. Admiraal, DOOFNL Consortium, Helger G. Yntema, Lies H. Hoefsloot, Ronald J. E. Pennings, Hannie Kremer

Hum Genet. 2018; 137(5): 389–400. Published online 2018 May 12. doi: 10.1007/s00439-018-1880-5

PMCID:: PMC5973959

Abstract Article PDF–1.6M

Select item 438366411.

Functional Consequences of 17q21.31/WNT3-WNT9B Amplification in hPSCs with respect to Neural Differentiation

Chun-Ting Lee, Raphael M. Bendriem, Abigail A. Kindberg, Lila T. Worden, Melanie P. Williams, Tomas Drgon, Barbara S. Mallon, Brandon K. Harvey, Christopher T. Richie, Rebecca S. Hamilton, Jia Chen, Stacie L. Errico, Shang-Yi A. Tsai, George R. Uhl, William J. Freed

Cell Rep. Author manuscript; available in PMC 2016 Feb 3.

Published in final edited form as: Cell Rep. 2015 Feb 3; 10(4): 616–632. Published online 2015 Jan 29. doi: 10.1016/j.celrep.2014.12.050

PMCID:: PMC4383664

Abstract Article PDF–2.7M

Select item 438092812.

Phospho-tyrosine dependent protein–protein interaction network

Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl

Mol Syst Biol. 2015 Mar; 11(3): 0794. Published online 2015 Mar 26. doi: 10.15252/msb.20145968

PMCID:: PMC4380928

Abstract Article PDF–1.9M

Select item 409198613.

Genome-Wide Data reveals Novel Genes for Methotrexate Response in a Large Cohort of Juvenile Idiopathic Arthritis Cases

Joanna Cobb, Erika Cule, Halima Moncrieffe, Anne Hinks, Simona Ursu, Fiona Patrick, Laura Kassoumeri, Edward Flynn, Maja Bulatovic, Nico Wulffraat, Bertrand van Zelst, Robert de Jonge, Marek Bohm, Pavla Dolezalova, Shashi Hirani, Stanton Newman, Pamela Whitworth, Taunton R Southwood, Childhood Arthritis Response to Medication Study (CHARMS), Childhood Arthritis Prospective Study (CAPS), BSPAR study group, Maria De Iorio, Lucy R Wedderburn, Wendy Thomson

Pharmacogenomics J. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Pharmacogenomics J. 2014 Aug; 14(4): 356–364. Published online 2014 Apr 8. doi: 10.1038/tpj.2014.3

PMCID:: PMC4091986

Abstract Article PDF–513K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 304420315.

Acetaminophen-NAPQI Hepatotoxicity: A Cell Line Model System Genome-Wide Association Study

Ann M. Moyer, Brooke L. Fridley, Gregory D. Jenkins, Anthony J. Batzler, Linda L. Pelleymounter, Krishna R. Kalari, Yuan Ji, Yubo Chai, Kendra K. S. Nordgren, Richard M. Weinshilboum

Toxicol Sci. 2011 Mar; 120(1): 33–41. Published online 2010 Dec 22. doi: 10.1093/toxsci/kfq375