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Select item 110963591.

TRIM25 predominately associates with anti-viral stress granules

Zehua Shang, Sitao Zhang, Jinrui Wang, Lili Zhou, Xinyue Zhang, Daniel D. Billadeau, Peiguo Yang, Lingqiang Zhang, Fangfang Zhou, Peng Bai, Da Jia

Nat Commun. 2024; 15: 4127. Published online 2024 May 15. doi: 10.1038/s41467-024-48596-4

PMCID:: PMC11096359

Abstract Article PDF–6.3M

Select item 109457072.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 109125093.

Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis

Yuanliang Yan, Shangjun Zhou, Xi Chen, Qiaoli Yi, Songshan Feng, Zijin Zhao, Yuanhong Liu, Qiuju Liang, Zhijie Xu, Zhi Li, Lunquan Sun

Signal Transduct Target Ther. 2024; 9: 58. Published online 2024 Mar 4. doi: 10.1038/s41392-024-01763-x

PMCID:: PMC10912509

Abstract Article PDF–5.9M

Select item 108358444.

TRIM25 promotes glioblastoma cell growth and invasion via regulation of the PRMT1/c-MYC pathway by targeting the splicing factor NONO

Yike Chen, Xiaohui Xu, Kaikai Ding, Tianchi Tang, Feng Cai, Haocheng Zhang, Zihang Chen, Yangjian Qi, Zaixiang Fu, Ganggui Zhu, Zhangqi Dou, Jinfang Xu, Gao Chen, Qun Wu, Jianxiong Ji, Jianmin Zhang

J Exp Clin Cancer Res. 2024; 43: 39. Published online 2024 Feb 2. doi: 10.1186/s13046-024-02964-6

PMCID:: PMC10835844

Abstract Article PDF–8.5M

Select item 107467005.

TRIM25 dictates selective miRNA loading into extracellular vesicles during inflammation

Kayla E. King, Priyanka Ghosh, Ann L. Wozniak

Sci Rep. 2023; 13: 22952. Published online 2023 Dec 22. doi: 10.1038/s41598-023-50336-5

PMCID:: PMC10746700

Abstract Article PDF–3.4M

Select item 106415246.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 105181007.

LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter

Ganglin Ren, Hongyan Li, Dan Hong, Fangyu Hu, Rongjia Jin, Shuang Wu, Wenhao Sun, Honglei Jin, Lingling Zhao, Xiaodong Zhang, Dongxiang Liu, Chuanshu Huang, Haishan Huang

BMC Cancer. 2023; 23: 898. Published online 2023 Sep 23. doi: 10.1186/s12885-023-11403-2

PMCID:: PMC10518100

Abstract Article PDF–10M

Select item 104549328.

TRIM25 Suppresses Rabies Virus Fixed HEP-Flury Strain Production by Activating RIG-1-Mediated Type I Interferons

Boyue Zhang, Ting Cai, Hongling He, Xuezhe Huang, Yongwen Luo, Shile Huang, Jun Luo, Xiaofeng Guo

Genes (Basel) 2023 Aug; 14(8): 1555. Published online 2023 Jul 29. doi: 10.3390/genes14081555

PMCID:: PMC10454932

Abstract Article PDF–4.0M

Select item 102374229.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1015086910.

TRIM25 inhibits HBV replication by promoting HBx degradation and the RIG-I-mediated pgRNA recognition

Hongxiao Song, Qingfei Xiao, Fengchao Xu, Qi Wei, Fei Wang, Guangyun Tan

Chin Med J (Engl) 2023 Apr 5; 136(7): 799–806. Published online 2023 Mar 28. doi: 10.1097/CM9.0000000000002617

PMCID:: PMC10150869

Abstract Article PDF–2.0M

Select item 1011932211.

RBM4 dictates ESCC cell fate switch from cellular senescence to glutamine-addiction survival through inhibiting LKB1-AMPK-axis

Lei Chen, Wenjing Zhang, Dan Chen, Quan Yang, Siwen Sun, Zhenwei Dai, Zhengzheng Li, Xuemei Liang, Chaoqun Chen, Yuexia Jiao, Lili Zhi, Lianmei Zhao, Jinrui Zhang, Xuefeng Liu, Jinyao Zhao, Man Li, Yang Wang, Yangfan Qi

Signal Transduct Target Ther. 2023; 8: 159. Published online 2023 Apr 21. doi: 10.1038/s41392-023-01367-x

PMCID:: PMC10119322

Abstract Article PDF–7.7M

Select item 1011163612.

O‐GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β‐catenin signalling

Zhongqi Cui, Jiangtu He, Jiabei Zhu, Wenxuan Ni, Li Liu, Zhixuan Bian, Siwei Mao, Song Gu, Yuhua Shan, Zhexuan Chu, Qi Wu, Jiayi Lu, Ya Liu, Fenyong Sun, Qiuhui Pan, Yue Zhang, Nan Huang, Ji Ma

Clin Transl Med. 2023 Apr; 13(4): e1239. Published online 2023 Apr 17. doi: 10.1002/ctm2.1239

PMCID:: PMC10111636

Abstract Article PDF–10M

Select item 1010449813.

The moonlighting function of glycolytic enzyme enolase-1 promotes choline phospholipid metabolism and tumor cell proliferation

Qingxia Ma, Hongfei Jiang, Leina Ma, Gaoxiang Zhao, Qianqian Xu, Dong Guo, Ningning He, Hao Liu, Zhaoyuan Meng, Juanjuan Liu, Lei Zhu, Qian Lin, Xiaolin Wu, Min Li, Shudi Luo, Jing Fang, Zhimin Lu

Proc Natl Acad Sci U S A. 2023 Apr 11; 120(15): e2209435120. Published online 2023 Apr 3. doi: 10.1073/pnas.2209435120

PMCID:: PMC10104498

Abstract Article PDF–7.4M

Select item 1000617214.

Hepatitis B virus X protein promotes MAN1B1 expression by enhancing stability of GRP78 via TRIM25 to facilitate hepatocarcinogenesis

Hongjuan You, Ning Zhang, Tong Yu, Lihong Ma, Qi Li, Xing Wang, Dongchen Yuan, Delong Kong, Xiangye Liu, Wei Hu, Dongsheng Liu, Fanyun Kong, Kuiyang Zheng, Renxian Tang

Br J Cancer. 2023 Apr 6; 128(6): 992–1004. Published online 2023 Jan 12. doi: 10.1038/s41416-022-02115-8

PMCID:: PMC10006172

Abstract Article PDF–3.0M

Select item 995772815.

UBE2J1 inhibits colorectal cancer progression by promoting ubiquitination and degradation of RPS3

Tuo Wang, Chi Jin, Peng Yang, Zhihao Chen, Jiangzhou Ji, Qingyang Sun, Sheng Yang, Yifei Feng, Junwei Tang, Yueming Sun

Oncogene. 2023; 42(9): 651–664. Published online 2022 Dec 26. doi: 10.1038/s41388-022-02581-7

PMCID:: PMC9957728

Abstract Article PDF–8.0M

Select item 995044716.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 981876817.

The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1

Usman Nasrullah, Kristina Stanke, Victoria Recknagel, Süleyman Bozkurt, Patrick Wurzel, Stefan Gauer, Gergely Imre, Christian Münch, Josef Pfeilschifter, Wolfgang Eberhardt

Cells. 2023 Jan; 12(1): 201. Published online 2023 Jan 3. doi: 10.3390/cells12010201

PMCID:: PMC9818768

Abstract Article PDF–7.7M

Select item 978132318.

Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells

Zening Yang, Jing Li, Jiali Li, Huiwen Zheng, Heng Li, Qingrun Lai, Yanli Chen, Li Qin, Yuanyuan Zuo, Lei Guo, Haijing Shi, Longding Liu

Vaccines (Basel) 2022 Dec; 10(12): 2042. Published online 2022 Nov 29. doi: 10.3390/vaccines10122042

PMCID:: PMC9781323

Abstract Article PDF–22M

Select item 977255819.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 976969820.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

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