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Items: 1 to 20 of 46

1.
Abnormal Expression of Rab27B in Prostatic Epithelial Cells of Benign Prostatic Hyperplasia Alters Intercellular Communication
Yu Dai, Bo Ai, Ying Liu, Laura E. Pascal, Zhou Wang, Rajiv Dhir, Xuegang Sun, Yu Jiang
Int J Biochem Cell Biol. Author manuscript; available in PMC 2024 Aug 7.
Published in final edited form as: Int J Biochem Cell Biol. 2021 Feb; 131: 105898. Published online 2020 Dec 4. doi: 10.1016/j.biocel.2020.105898
PMCID:
PMC11305165
AbstractArticlePDF–1.8M
2.
A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy
Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald
Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535
PMCID:
PMC10345963
AbstractArticlePDF–13M
3.
RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia
Jian-Gang Ren, Bowen Xing, Kaosheng Lv, Rachel A. O’Keefe, Mengfang Wu, Ruoxing Wang, Kaylyn M. Bauer, Arevik Ghazaryan, George M. Burslem, Jing Zhang, Ryan M. O’Connell, Vinodh Pillai, Elizabeth O. Hexner, Mark R. Philips, Wei Tong
J Clin Invest. 2023 Jun 15; 133(12): e165510. Published online 2023 Jun 15. doi: 10.1172/JCI165510
PMCID:
PMC10266782
AbstractArticlePDF–2.8M
4.
RAB27B Drives a Cancer Stem Cell Phenotype in NSCLC Cells Through Enhanced Extracellular Vesicle Secretion
Kayleah M. Meneses, Prita Pandya, Jennifer A. Lindemann, Dania S. Al-Qasrawi, Ryan A. Argo, Celeste M. Weems, Danielle J. Beetler, Geraldine V. Vijay, Irene K. Yan, Joy Wolfram, Tushar Patel, Verline Justilien
Cancer Res Commun. 2023 Apr; 3(4): 607–620. Published online 2023 Apr 17. doi: 10.1158/2767-9764.CRC-22-0425
PMCID:
PMC10109210
AbstractArticlePDF–16M
5.
Rab27b, a Regulator of Exosome Secretion, Is Associated With Peritoneal Metastases in Gastric Cancer
SHO NAMBARA, TAKAAKI MASUDA, KOSUKE HIROSE, QINGJIANG HU, TARO TOBO, YUKI OZATO, JUNJI KURASHIGE, YOSHIKI HIRAKI, YUICHI HISAMATSU, TOMOHIRO IGUCHI, KEISHI SUGIMACHI, EIJI OKI, TOMOHARU YOSHIZUMI, KOSHI MIMORI
Cancer Genomics Proteomics. 2023 Jan-Feb; 20(1): 30–39. Published online 2023 Jan 3. doi: 10.21873/cgp.20362
PMCID:
PMC9806673
AbstractArticlePDF–3.3M
6.
RAB27A and RAB27B Expression May Predict Lymph Node Metastasis and Survival in Patients With Gastric Cancer
HYO JUNG AN, JONG SIL LEE, JUNG WOOK YANG, MIN HYE KIM, JI MIN NA, DAE HYUN SONG
Cancer Genomics Proteomics. 2022 Sep-Oct; 19(5): 606–613. Published online 2022 Sep 3. doi: 10.21873/cgp.20345
PMCID:
PMC9353728
AbstractArticlePDF–2.9M
7.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
8.
Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
Sonja Fernbach, Eva E. Spieler, Idoia Busnadiego, Umut Karakus, Anouk Lkharrazi, Silke Stertz, Benjamin G. Hale
Cell Rep. 2022 Mar 22; 38(12): 110549. Published online 2022 Mar 22. doi: 10.1016/j.celrep.2022.110549
PMCID:
PMC8939003
AbstractArticlePDF–5.6M
9.
Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma
Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim
Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6
PMCID:
PMC8566473
AbstractArticlePDF–2.7M
10.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
11.
Human multipotent mesenchymal stromal cells cytokine priming promotes RAB27B-regulated secretion of small extracellular vesicles with immunomodulatory cargo
Anastasia Cheng, Dongsic Choi, Maximilien Lora, Dominique Shum-Tim, Janusz Rak, Inés Colmegna
Stem Cell Res Ther. 2020; 11: 539. Published online 2020 Dec 14. doi: 10.1186/s13287-020-02050-6
PMCID:
PMC7734842
AbstractArticlePDF–2.2M
12.
Inhibition of Rab27a and Rab27b Has Opposite Effects on the Regulation of Hair Cycle and Hair Growth
Kyung-Eun Ku, Nahyun Choi, Jong-Hyuk Sung
Int J Mol Sci. 2020 Aug; 21(16): 5672. Published online 2020 Aug 7. doi: 10.3390/ijms21165672
PMCID:
PMC7460818
AbstractArticlePDF–3.6M
13.
A hypoxia-induced Rab pathway regulates embryo implantation by controlled trafficking of secretory granules
Arpita Bhurke, Athilakshmi Kannan, Alison Neff, Qiuyan Ma, Mary J. Laws, Robert N. Taylor, Milan K. Bagchi, Indrani C. Bagchi
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14532–14542. Published online 2020 Jun 8. doi: 10.1073/pnas.2000810117
PMCID:
PMC7321991
AbstractArticlePDF–2.4M
14.
Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation
Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux
Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070
PMCID:
PMC7290721
AbstractArticlePDF–9.2M
15.
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of α-synuclein
Rachel Underwood, Bing Wang, Christine Carico, Robert H. Whitaker, William J. Placzek, Talene A. Yacoubian
J Biol Chem. 2020 Jun 5; 295(23): 8005–8016. Published online 2020 Apr 29. doi: 10.1074/jbc.RA120.013337
PMCID:
PMC7278354
AbstractArticlePDF–2.5M
16.
Oncogenic effects of RAB27B through exosome independent function in renal cell carcinoma including sunitinib-resistant
Masafumi Tsuruda, Hirofumi Yoshino, Shunsuke Okamura, Kazuki Kuroshima, Yoichi Osako, Takashi Sakaguchi, Satoshi Sugita, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida
PLoS One. 2020; 15(5): e0232545. Published online 2020 May 7. doi: 10.1371/journal.pone.0232545
PMCID:
PMC7205224
AbstractArticlePDF–14M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
19.
FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane
Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri
Structure. Author manuscript; available in PMC 2020 Jun 4.
Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022
PMCID:
PMC6551266
AbstractArticlePDF–3.4M
20.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M

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