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Select item 109359541.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 107773512.

Magnetic Yeast Glucan Particles for Antibody-Free Separation of Viable Macrophages from Drosophila melanogaster

Gabriela Krejčová, Ivan Saloň, Vojtěch Klimša, Pavel Ulbrich, Ayse Beyza Aysan, Adam Bajgar, František Štěpánek

ACS Biomater Sci Eng. 2024 Jan 8; 10(1): 355–364. Published online 2023 Dec 4. doi: 10.1021/acsbiomaterials.3c01199

PMCID:: PMC10777351

Abstract Article PDF–7.3M

Select item 106821753.

PARP-1 is a transcriptional rheostat of metabolic and bivalent genes during development

Gbolahan Bamgbose, Alexei Tulin

Life Sci Alliance. 2024 Feb; 7(2): e202302369. Published online 2023 Nov 27. doi: 10.26508/lsa.202302369

PMCID:: PMC10682175

Abstract Article PDF–3.8M

Select item 105756294.

Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

Liang-Yu Pang, Steven DeLuca, Haolong Zhu, John M Urban, Allan C Spradling

eLife. 2023; 12: RP90509. Published online 2023 Oct 13. doi: 10.7554/eLife.90509

PMCID:: PMC10575629

Abstract Article PDF–6.3M

Select item 104276965.

REPTOR and CREBRF encode key regulators of muscle energy metabolism

Pedro Saavedra, Phillip A. Dumesic, Yanhui Hu, Elizabeth Filine, Patrick Jouandin, Richard Binari, Sarah E. Wilensky, Jonathan Rodiger, Haiyun Wang, Weihang Chen, Ying Liu, Bruce M. Spiegelman, Norbert Perrimon

Nat Commun. 2023; 14: 4943. Published online 2023 Aug 15. doi: 10.1038/s41467-023-40595-1

PMCID:: PMC10427696

Abstract Article PDF–6.5M

Select item 103177846.

Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors

Joshua B. Benoit, Joy Bose, Samuel T. Bailey, Michal Polak

Parasitology. 2020 Sep; 147(11): 1196–1205. Published online 2020 Jun 5. doi: 10.1017/S0031182020000918

PMCID:: PMC10317784

Abstract Article PDF–602K

Select item 100789177.

A modERN resource: identification of Drosophila transcription factor candidate target genes using RNAi

William W Fisher, Ann S Hammonds, Richard Weiszmann, Benjamin W Booth, Louis Gevirtzman, Jaeda E J Patton, Connor A Kubo, Robert H Waterston, Susan E Celniker

Genetics. 2023 Apr; 223(4): iyad004. Published online 2023 Jan 19. doi: 10.1093/genetics/iyad004

PMCID:: PMC10078917

Abstract Article PDF–18M

Select item 95236458.

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis

Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han

Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6

PMCID:: PMC9523645

Abstract Article PDF–3.9M

Select item 90381199.

Targeting metabolic pathways for extension of lifespan and healthspan across multiple species

Andrey A. Parkhitko, Elizabeth Filine, Stephanie E. Mohr, Alexey Moskalev, Norbert Perrimon

Ageing Res Rev. Author manuscript; available in PMC 2022 Apr 25.

Published in final edited form as: Ageing Res Rev. 2020 Dec; 64: 101188. Published online 2020 Oct 5. doi: 10.1016/j.arr.2020.101188

PMCID:: PMC9038119

Abstract Article PDF–2.0M

Select item 882470110.

Liam C Hunt, Fabio Demontis

J Gerontol A Biol Sci Med Sci. 2022 Feb; 77(2): 259–267. Published online 2021 Sep 3. doi: 10.1093/gerona/glab260

PMCID:: PMC8824701

Abstract Article PDF–8.5M

Select item 877410611.

Sexual Dimorphism in Metabolic Responses to Western Diet in Drosophila melanogaster

Sofie De Groef, Tom Wilms, Séverine Balmand, Federica Calevro, Patrick Callaerts

Biomolecules. 2022 Jan; 12(1): 33. Published online 2021 Dec 27. doi: 10.3390/biom12010033

PMCID:: PMC8774106

Abstract Article PDF–1.9M

Select item 866448612.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 863399013.

Ecdysone and 20-hydroxyecdysone are not required to activate glycolytic gene expression in Drosophila melanogaster embryos

Jason M. Tennessen

MicroPubl Biol. 2021; 2021: 10.17912/micropub.biology.000501. Published online 2021 Nov 30. doi: 10.17912/micropub.biology.000501

PMCID:: PMC8633990

Abstract Article PDF–519K

Select item 860230914.

GAPDH controls extracellular vesicle biogenesis and enhances the therapeutic potential of EV mediated siRNA delivery to the brain

Ghulam Hassan Dar, Cláudia C. Mendes, Wei-Li Kuan, Alfina A. Speciale, Mariana Conceição, André Görgens, Inna Uliyakina, Miguel J. Lobo, Wooi F. Lim, Samir EL Andaloussi, Imre Mäger, Thomas C. Roberts, Roger A. Barker, Deborah C. I. Goberdhan, Clive Wilson, Matthew J. A. Wood

Nat Commun. 2021; 12: 6666. Published online 2021 Nov 18. doi: 10.1038/s41467-021-27056-3

Correction in:: Nat Commun. 2021; 12: 7357.

PMCID:: PMC8602309

Abstract Article PDF–2.9M

Select item 853036315.

Metabolic gene regulation by Drosophila GATA transcription factor Grain

Krista Kokki, Nicole Lamichane, Anni I. Nieminen, Hanna Ruhanen, Jack Morikka, Marius Robciuc, Bohdana M. Rovenko, Essi Havula, Reijo Käkelä, Ville Hietakangas

PLoS Genet. 2021 Oct; 17(10): e1009855. Published online 2021 Oct 11. doi: 10.1371/journal.pgen.1009855

PMCID:: PMC8530363

Abstract Article PDF–5.4M

Select item 780680816.

Increasing neuronal glucose uptake attenuates brain aging and promotes life span under dietary restriction in Drosophila

Mikiko Oka, Emiko Suzuki, Akiko Asada, Taro Saito, Koichi M. Iijima, Kanae Ando

iScience. 2021 Jan 22; 24(1): 101979. Published online 2021 Jan 5. doi: 10.1016/j.isci.2020.101979

PMCID:: PMC7806808

Abstract Article PDF–9.3M

Select item 770717117.

Nuclear translocation ability of Lipin differentially affects gene expression and survival in fed and fasting Drosophila

Stephanie E. Hood, Xeniya V. Kofler, Quiyu Chen, Judah Scott, Jason Ortega, Michael Lehmann

J Lipid Res. 2020 Dec; 61(12): 1720–1732. Published online 2020 Sep 28. doi: 10.1194/jlr.RA120001051

PMCID:: PMC7707171

Abstract Article PDF–1.0M

Select item 686771118.

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense

Gabriela Krejčová, Adéla Danielová, Pavla Nedbalová, Michalina Kazek, Lukáš Strych, Geetanjali Chawla, Jason M Tennessen, Jaroslava Lieskovská, Marek Jindra, Tomáš Doležal, Adam Bajgar

eLife. 2019; 8: e50414. Published online 2019 Oct 14. doi: 10.7554/eLife.50414

PMCID:: PMC6867711

Abstract Article PDF–3.8M

Select item 670028219.

Sex Differences in Intestinal Carbohydrate Metabolism Promote Food Intake and Sperm Maturation

Bruno Hudry, Eva de Goeij, Alessandro Mineo, Pedro Gaspar, Dafni Hadjieconomou, Chris Studd, Joao B. Mokochinski, Holger B. Kramer, Pierre-Yves Plaçais, Thomas Preat, Irene Miguel-Aliaga

Cell. 2019 Aug 8; 178(4): 901–918.e16. doi: 10.1016/j.cell.2019.07.029