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Items: 1 to 20 of 122

1.
Inherited human RelB deficiency impairs innate and adaptive immunity to infection
Tom Le Voyer, Majistor Raj Luxman Maglorius Renkilaraj, Kunihiko Moriya, Malena Pérez Lorenzo, Tina Nguyen, Liwei Gao, Tamar Rubin, Axel Cederholm, Masato Ogishi, Carlos A. Arango-Franco, Vivien Béziat, Romain Lévy, Mélanie Migaud, Franck Rapaport, Yuval Itan, Elissa K. Deenick, Irene Cortese, Andrea Lisco, Kaan Boztug, Laurent Abel, Stéphanie Boisson-Dupuis, Bertrand Boisson, Patrick Frosk, Cindy S. Ma, Nils Landegren, Fatih Celmeli, Jean-Laurent Casanova, Stuart G. Tangye, Anne Puel
Proc Natl Acad Sci U S A. 2024 Sep 10; 121(37): e2321794121. Published online 2024 Sep 4. doi: 10.1073/pnas.2321794121
PMCID:
PMC11406260
AbstractArticlePDF–4.2M
2.
NFκB pathway dysregulation due to reduced RelB expression leads to severe autoimmune disorders and declining immunity
Nigel Sharfe, Ilan Dalal, Zahra Naghdi, Diane Lefaudeux, Linda Vong, Harjit Dadi, Hector Navarro, Diana Tasher, Adi Ovadia, Tzili Zangen, Dorit Ater, Bo Ngan, Alexander Hoffmann, Chaim M. Roifman
J Autoimmun. Author manuscript; available in PMC 2024 Feb 12.
Published in final edited form as: J Autoimmun. 2023 May; 137: 102946. Published online 2022 Nov 17. doi: 10.1016/j.jaut.2022.102946
PMCID:
PMC10861023
AbstractArticlePDF–2.5M
3.
Inflammation in Hypervolemic Hemodialysis Patients: The Roles of RelB and Caspase-4
Christof Ulrich, Zeynep Canim, Eva Herberger, Matthias Girndt, Roman Fiedler
Int J Mol Sci. 2023 Dec; 24(24): 17550. Published online 2023 Dec 16. doi: 10.3390/ijms242417550
PMCID:
PMC10743509
AbstractArticlePDF–1.6M
4.
NF-κB Signaling Modulates miR-452-5p and miR-335-5p Expression to Functionally Decrease Epithelial Ovarian Cancer Progression in Tumor-Initiating Cells
Rahul D. Kamdar, Brittney S. Harrington, Emma Attar, Soumya Korrapati, Jyoti Shetty, Yongmei Zhao, Bao Tran, Nathan Wong, Carrie D. House, Christina M. Annunziata
Int J Mol Sci. 2023 May; 24(9): 7826. Published online 2023 Apr 25. doi: 10.3390/ijms24097826
PMCID:
PMC10178396
AbstractArticlePDF–2.1M
5.
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling
Laura B. Kuhn, Stefanie Valentin, Kristina Stojanovic, Daniel C. Strobl, Tea Babushku, Yan Wang, Ursula Rambold, Laura Scheffler, Sonja Grath, Dorothy John-Robbert, Helmut Blum, Annette Feuchtinger, Andreas Blutke, Falk Weih, Daisuke Kitamura, Roland Rad, Lothar J. Strobl, Ursula Zimber-Strobl
Front Immunol. 2022; 13: 913275. Published online 2022 Aug 30. doi: 10.3389/fimmu.2022.913275
PMCID:
PMC9468873
AbstractArticlePDF–12M
6.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
7.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
8.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
9.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
10.
Crosstalk between Heart Failure and Cognitive Impairment via hsa-miR-933/RELB/CCL21 Pathway
Wenxiao Feng, Jie Yang, Wenchao Song, Yitao Xue
Biomed Res Int. 2021; 2021: 2291899. Published online 2021 Sep 18. doi: 10.1155/2021/2291899
PMCID:
PMC8478533
AbstractArticlePDF–4.0M
11.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Serum RelB is correlated with renal fibrosis and predicts chronic kidney disease progression
Donglin Sun, Ningxia Xie, Xi Wang, Wenquan Wu, Xiu‐Yong Li, Xiangqiu Chen, Guojun Qian, Cuifeng Li, Haohao Zhang, Yuhang Jiang, Deji Ye, Dandan Liu, Yiming Hu, Jingyao Wang, Weifeng Chen, Qiumei Zhao, Min Zeng, Junwei Zhang, Li Wang, Xiaoren Zhang
Clin Transl Med. 2021 May; 11(5): e362. Published online 2021 May 21. doi: 10.1002/ctm2.362
PMCID:
PMC8140188
ArticlePDF–1.5M
14.
E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation
Jie-Lin Duan, Hui-Qian He, Yao Yu, Tao Liu, Shu-Jun Ma, Fan Li, Yan-Shan Jiang, Xin Lin, De-Dong Li, Quan-Zhen Lv, Hui-Hui Ma, Xin-Ming Jia
Sci Adv. 2021 May; 7(19): eabe5171. Published online 2021 May 7. doi: 10.1126/sciadv.abe5171
PMCID:
PMC8104877
AbstractArticlePDF–9.3M
15.
The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits
Izaskun Mitxitorena, Domenico Somma, Jennifer P. Mitchell, Matti Lepistö, Christian Tyrchan, Emma L. Smith, Patrick A. Kiely, Helen Walden, Karen Keeshan, Ruaidhrí J. Carmody
J Biol Chem. 2020 Aug 14; 295(33): 11754–11763. Published online 2020 Jun 25. doi: 10.1074/jbc.RA120.014113
PMCID:
PMC7450122
AbstractArticlePDF–2.5M
16.
RelB sustains endocrine resistant malignancy: an insight of noncanonical NF-κB pathway into breast Cancer progression
Mei Wang, Yanyan Zhang, Zhi Xu, Peipei Qian, Wenbo Sun, Xiumei Wang, Zhang Jian, Tiansong Xia, Yong Xu, Jinhai Tang
Cell Commun Signal. 2020; 18: 128. Published online 2020 Aug 17. doi: 10.1186/s12964-020-00613-x
PMCID:
PMC7430126
AbstractArticlePDF–6.1M
17.
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2
Chunqing Wang, Yongmei Li, Shuai Yan, Hao Wang, Xianfeng Shao, Mingming Xiao, Baicai Yang, Guoxuan Qin, Ruirui Kong, Ruibing Chen, Ning Zhang
Nat Commun. 2020; 11: 3162. Published online 2020 Jun 22. doi: 10.1038/s41467-020-16966-3
PMCID:
PMC7308313
AbstractArticlePDF–2.9M
18.
GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein
Jing Cheng, Linda R. Klei, Nathaniel E. Hubel, Ming Zhang, Rebekka Schairer, Lisa M. Maurer, Hanna B. Klei, Heejae Kang, Vincent J. Concel, Phillip C. Delekta, Eric V. Dang, Michelle A. Mintz, Mathijs Baens, Jason G. Cyster, Narayanan Parameswaran, Margot Thome, Peter C. Lucas, Linda M. McAllister-Lucas
J Clin Invest. 2020 Feb 3; 130(2): 1036–1051. Published online 2020 Jan 21. doi: 10.1172/JCI97040
PMCID:
PMC6994119
AbstractArticlePDF–8.3M
19.
Switch of NAD Salvage to de novo Biosynthesis Sustains SIRT1-RelB-Dependent Inflammatory Tolerance
Jingpu Zhang, Jie Tao, Yun Ling, Feng Li, Xuewei Zhu, Li Xu, Mei Wang, Shuye Zhang, Charles E. McCall, Tie Fu Liu
Front Immunol. 2019; 10: 2358. Published online 2019 Oct 11. doi: 10.3389/fimmu.2019.02358
PMCID:
PMC6797595
AbstractArticlePDF–1.2M
20.
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer
Tânia D. F. Costa, Ting Zhuang, Julie Lorent, Emilia Turco, Helene Olofsson, Miriam Masia-Balague, Miao Zhao, Parisa Rabieifar, Neil Robertson, Raoul Kuiper, Jonas Sjölund, Matthias Spiess, Pablo Hernández-Varas, Uta Rabenhorst, Pernilla Roswall, Ran Ma, Xiaowei Gong, Johan Hartman, Kristian Pietras, Peter D. Adams, Paola Defilippi, Staffan Strömblad
Nat Commun. 2019; 10: 3589. Published online 2019 Aug 9. doi: 10.1038/s41467-019-11510-4
PMCID:
PMC6689091
AbstractArticlePDF–2.6M

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