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Select item 110740231.

Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules

Lukas Zierke, Daniel John, Marcel Gischke, Quang Trung Tran, Matthias Sendler, Frank Ulrich Weiss, Uwe T. Bornscheuer, Christoph Ritter, Markus M. Lerch, Ali A. Aghdassi

Cell Mol Life Sci. 2024 Dec; 81(1): 207. Published online 2024 May 6. doi: 10.1007/s00018-024-05247-7

PMCID:: PMC11074023

Abstract Article PDF–6.5M

Select item 87266082.

CREG1 promotes lysosomal biogenesis and function

Jie Liu, Yanmei Qi, Joshua Chao, Pranav Sathuvalli, Leonard Y. Lee, Shaohua Li

Autophagy. 2021; 17(12): 4249–4265. Published online 2021 May 8. doi: 10.1080/15548627.2021.1909997

PMCID:: PMC8726608

Abstract Article PDF–9.2M

Select item 71658933.

Cathepsin C limits acute viral infection independently of NK cell and CD8⁺ T‐cell cytolytic function

Christopher E Andoniou, Peter Fleming, Vivien R Sutton, Joseph A Trapani, Mariapia A Degli‐Esposti

Immunol Cell Biol. 2011 May-Jun; 89(4): 540–548. Published online 2010 Oct 26. doi: 10.1038/icb.2010.115

PMCID:: PMC7165893

Abstract Article PDF–662K

Select item 66080574.

Frontline Science: Multiple cathepsins promote inflammasome‐independent, particle‐induced cell death during NLRP3‐dependent IL‐1β activation

Gregory M. Orlowski, Shruti Sharma, Jeff D. Colbert, Matthew Bogyo, Stephanie A. Robertson, Hiroshi Kataoka, Francis K. Chan, Kenneth L. Rock

J Leukoc Biol. 2017 Jul; 102(1): 7–17. Published online 2017 Jan 13. doi: 10.1189/jlb.3HI0316-152R

PMCID:: PMC6608057

Abstract Article

Select item 63358045.

Cathepsin C promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca²⁺-dependent PKC/p38MAPK/NF-κB pathway

Qing Liu, Yanli Zhang, Shuang Liu, Yanna Liu, Xiaohan Yang, Gang Liu, Takahiro Shimizu, Kazuhiro Ikenaka, Kai Fan, Jianmei Ma

J Neuroinflammation. 2019; 16: 10. Published online 2019 Jan 16. doi: 10.1186/s12974-019-1398-3

Correction in:: J Neuroinflammation. 2022; 19: 14.

PMCID:: PMC6335804

Abstract Article PDF–5.4M

Select item 63338816.

Deficiency of cathepsin C ameliorates severity of acute pancreatitis by reduction of neutrophil elastase activation and cleavage of E-cadherin

Daniel S. John, Julia Aschenbach, Burkhard Krüger, Matthias Sendler, F. Ulrich Weiss, Julia Mayerle, Markus M. Lerch, Ali A. Aghdassi

J Biol Chem. 2019 Jan 11; 294(2): 697–707. Published online 2018 Nov 19. doi: 10.1074/jbc.RA118.004376

PMCID:: PMC6333881

Abstract Article PDF–2.3M

Select item 62980407.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 62627778.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 58202489.

Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

Ian C. Scott, Jayesh B. Majithiya, Caroline Sanden, Peter Thornton, Philip N. Sanders, Tom Moore, Molly Guscott, Dominic J. Corkill, Jonas S. Erjefält, E. Suzanne Cohen

Sci Rep. 2018; 8: 3363. Published online 2018 Feb 20. doi: 10.1038/s41598-018-21589-2

PMCID:: PMC5820248

Abstract Article PDF–2.5M

Select item 555919910.

STAT3 and STAT6 signaling pathways synergize to promote cathepsin secretion from macrophages via IRE1α activation

Dongyao Yan, Hao-Wei Wang, Robert L. Bowman, Johanna A. Joyce

Cell Rep. Author manuscript; available in PMC 2017 Aug 16.

Published in final edited form as: Cell Rep. 2016 Sep 13; 16(11): 2914–2927. doi: 10.1016/j.celrep.2016.08.035

PMCID:: PMC5559199

Abstract Article PDF–1.0M

Select item 530510511.

Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice

Rujuan Dai, Catharine Cowan, Bettina Heid, Deena Khan, Zhihong Liang, Christine T. N. Pham, S. Ansar Ahmed

PLoS One. 2017; 12(2): e0172105. Published online 2017 Feb 13. doi: 10.1371/journal.pone.0172105

PMCID:: PMC5305105

Abstract Article PDF–2.0M

Select item 522315912.

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression

Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes

Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495

PMCID:: PMC5223159

Abstract Article PDF–2.3M

Select item 517539713.

Disinhibition of Cathepsin C Caused by Cystatin F Deficiency Aggravates the Demyelination in a Cuprizone Model

Junjie Liang, Ning Li, Yanli Zhang, Changyi Hou, Xiaohan Yang, Takahiro Shimizu, Xiaoyu Wang, Kazuhiro Ikenaka, Kai Fan, Jianmei Ma

Front Mol Neurosci. 2016; 9: 152. Published online 2016 Dec 21. doi: 10.3389/fnmol.2016.00152

Correction in:: Front Mol Neurosci. 2018; 11: 115.

PMCID:: PMC5175397

Abstract Article PDF–4.2M

Select item 486142214.

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases

Yveline Hamon, Monika Legowska, Virginie Hervé, Sandrine Dallet-Choisy, Sylvain Marchand-Adam, Lise Vanderlynden, Michèle Demonte, Rich Williams, Christopher J. Scott, Mustapha Si-Tahar, Nathalie Heuzé-Vourc'h, Gilles Lalmanach, Dieter E. Jenne, Adam Lesner, Francis Gauthier, Brice Korkmaz

J Biol Chem. 2016 Apr 15; 291(16): 8486–8499. Published online 2016 Feb 16. doi: 10.1074/jbc.M115.707109

PMCID:: PMC4861422

Abstract Article PDF–2.4M

Select item 484343915.

NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis

Prajwal Gurung, Amanda Burton, Thirumala-Devi Kanneganti

Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16): 4452–4457. Published online 2016 Apr 6. doi: 10.1073/pnas.1601636113

PMCID:: PMC4843439

Abstract Article PDF–989K

Select item 461498216.

Distinct cathepsins control necrotic cell death mediated by pyroptosis inducers and lysosome-destabilizing agents

Jürgen Brojatsch, Heriberto Lima, Jr., Deborah Palliser, Lee S Jacobson, Stefan M Muehlbauer, Raquel Furtado, David L Goldman, Michael P Lisanti, Kartik Chandran

Cell Cycle. 2015 Apr 1; 14(7): 964–972. Published online 2015 Apr 1. doi: 10.4161/15384101.2014.991194

PMCID:: PMC4614982

Abstract Article PDF–764K

Select item 441868917.

Regulation of Hepatocyte Growth Factor in Mice with Pneumonia by Peptidases and Trans-Alveolar Flux

Wilfred W. Raymond, Xiang Xu, Shilpa Nimishakavi, Catherine Le, Donald M. McDonald, George H. Caughey

PLoS One. 2015; 10(5): e0125797. Published online 2015 May 4. doi: 10.1371/journal.pone.0125797

PMCID:: PMC4418689

Abstract Article PDF–15M

Select item 435348818.

Dipeptidyl-peptidase I does not functionally compensate for the loss of tripeptidyl-peptidase I in the neurodegenerative disease late-infantile neuronal ceroid lipofuscinosis

Kwi-Hye Kim, Christine T. Pham, David E. Sleat, Peter Lobel

Biochem J. Author manuscript; available in PMC 2015 Mar 9.

Published in final edited form as: Biochem J. 2008 Oct 15; 415(2): 225–232. doi: 10.1042/BJ20080411

PMCID:: PMC4353488

Abstract Article PDF–3.1M

Select item 427084219.

Leukocyte Cathepsin C deficiency attenuates atherosclerotic lesion progression by selective tuning of innate and adaptive immune responses

MV Herías, EAL Biessen, C Beckers, D Delsing, M Liao, MJ Daemen, CTN Pham, S Heeneman

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Jan; 35(1): 79–86. Published online 2014 Nov 13. doi: 10.1161/ATVBAHA.114.304292

PMCID:: PMC4270842

Abstract Article PDF–914K

Select item 410711020.

Dipeptidyl Peptidase I Controls Survival from Klebsiella pneumoniae Lung Infection by Processing Surfactant Protein D

Rachel E. Sutherland, Sophia S. Barry, Joanna S. Olsen, D. Brenda Salantes, George H. Caughey, Paul J. Wolters

Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Jul 18.

Published in final edited form as: Biochem Biophys Res Commun. 2014 Jul 18; 450(1): 818–823. Published online 2014 Jun 21. doi: 10.1016/j.bbrc.2014.06.062

PMCID:: PMC4107110

Abstract Article PDF–822K

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