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Select item 110669761.

FTY720 requires vitamin B₁₂-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis

Deepa Jonnalagadda, Yasuyuki Kihara, Aran Groves, Manisha Ray, Arjun Saha, Clayton Ellington, Hyeon-Cheol Lee-Okada, Tomomi Furihata, Takehiko Yokomizo, Edward V. Quadros, Richard Rivera, Jerold Chun

Cell Rep. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113545. Published online 2023 Dec 7. doi: 10.1016/j.celrep.2023.113545

PMCID:: PMC11066976

Abstract Article PDF–2.3M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 82616653.

Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4

Bingxiang Wang, Yishi Shen, Lei Zhai, Xiaodan Xia, Hong-mei Gu, Maggie Wang, Yongfang Zhao, Xiaole Chang, Adekunle Alabi, Sijie Xing, Shijun Deng, Boyan Liu, Guiqing Wang, Shucun Qin, Da-wei Zhang

J Lipid Res. 2021; 62: 100091. Published online 2021 Jun 9. doi: 10.1016/j.jlr.2021.100091

PMCID:: PMC8261665

Abstract Article PDF–5.1M

Select item 80026164.

Intracellular and Tissue Levels of Vitamin B12 in Hepatocytes Are Modulated by CD320 Receptor and TCN2 Transporter

Joseph Boachie, Antonysunil Adaikalakoteswari, Ilona Goljan, Jinous Samavat, Felino R. Cagampang, Ponnusamy Saravanan

Int J Mol Sci. 2021 Mar; 22(6): 3089. Published online 2021 Mar 17. doi: 10.3390/ijms22063089

PMCID:: PMC8002616

Abstract Article PDF–1.2M

Select item 67250495.

Reelin, Very-Low-Density Lipoprotein Receptor, and Apolipoprotein E Receptor 2 Control Somatic NMDA Receptor Composition during Hippocampal Maturation In Vitro

Mélanie Sinagra, Danièle Verrier, Daniela Frankova, Kimberly M. Korwek, Jaroslav Blahos, Edwin J. Weeber, Olivier J. Manzoni, Pascale Chavis

J Neurosci. 2005 Jun 29; 25(26): 6127–6136. doi: 10.1523/JNEUROSCI.1757-05.2005

PMCID:: PMC6725049

Abstract Article PDF–379K

Select item 63386256.

Neuropathology of vitamin B₁₂ deficiency in the Cd320^−/− mouse

Kaveri Arora, Jeffrey M. Sequeira, Juan M. Alarcon, Brandi Wasek, Erland Arning, Teodoro Bottiglieri, Edward V. Quadros

FASEB J. 2019 Feb; 33(2): 2563–2573. Published online 2018 Oct 10. doi: 10.1096/fj.201800754RR

PMCID:: PMC6338625

Abstract Article

Select item 62980407.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 61689738.

Mice lacking the transcobalamin-vitamin B12 receptor, CD320, suffer from anemia and reproductive deficits when fed vitamin B12-deficient diet

David J Bernard, Faith J Pangilinan, Jun Cheng, Anne M Molloy, Lawrence C Brody

Hum Mol Genet. 2018 Oct 15; 27(20): 3627–3640. Published online 2018 Aug 15. doi: 10.1093/hmg/ddy267

PMCID:: PMC6168973

Abstract Article PDF–3.4M

Select item 61256449.

Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR

Shyue-Fang Battaglia-Hsu, Rose Ghemrawi, David Coelho, Natacha Dreumont, Pauline Mosca, Sébastien Hergalant, Guillaume Gauchotte, Jeffrey M Sequeira, Mariam Ndiongue, Rémi Houlgatte, Jean-Marc Alberto, Remy Umoret, Aurélie Robert, Justine Paoli, Martin Jung, Edward V Quadros, Jean-Louis Guéant

Nucleic Acids Res. 2018 Sep 6; 46(15): 7844–7857. Published online 2018 Jul 17. doi: 10.1093/nar/gky634

PMCID:: PMC6125644

Abstract Article PDF–10M

Select item 547152410.

Maternofetal transport of vitamin B₁₂: role of TCblR/CD320 and megalin

Kaveri Arora, Jeffrey M. Sequeira, Edward V. Quadros

FASEB J. 2017 Jul; 31(7): 3098–3106. Published online 2017 Mar 28. doi: 10.1096/fj.201700025R

PMCID:: PMC5471524

Abstract Article

Select item 543665011.

Behavioral alterations are associated with vitamin B₁₂ deficiency in the transcobalamin receptor/CD320 KO mouse

Kaveri Arora, Jeffrey M. Sequeira, Alejandro I. Hernández, Juan M. Alarcon, Edward V. Quadros

PLoS One. 2017; 12(5): e0177156. Published online 2017 May 18. doi: 10.1371/journal.pone.0177156

PMCID:: PMC5436650

Abstract Article PDF–24M

Select item 526812612.

Human LDL Receptor Enhances Sequestration of ApoE4 and VLDL Remnants on the Surface of Hepatocytes but Not Their Internalization in Mice

Michael Altenburg, Jose Arbones-Mainar, Lance Johnson, Jennifer Wilder, Nobuyo Maeda

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jan 26.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2008 Jun; 28(6): 1104–1110. Published online 2008 Mar 27. doi: 10.1161/ATVBAHA.108.164863

PMCID:: PMC5268126

Abstract Article PDF–1.3M

Select item 489127713.

A new plasmid-based microRNA inhibitor system that inhibits microRNA families in transgenic mice and cells: a potential new therapeutic reagent

H Cao, W Yu, X Li, J Wang, S Gao, N E Holton, S Eliason, T Sharp, B A Amendt

Gene Ther. 2016 Jun; 23(6): 527–542. Prepublished online 2016 Mar 2. Published online 2016 Apr 7. doi: 10.1038/gt.2016.22

Correction in:: Gene Ther. 2016 Jul; 23(7): 634.

PMCID:: PMC4891277

Abstract Article PDF–3.2M

Select item 466427114.

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene

Nadezhda Logunova, Maria Korotetskaya, Vladimir Polshakov, Alexander Apt

PLoS Genet. 2015 Nov; 11(11): e1005672. Published online 2015 Nov 30. doi: 10.1371/journal.pgen.1005672

PMCID:: PMC4664271

Abstract Article PDF–8.4M

Select item 365935715.

The transcobalamin receptor knockout mouse: a model for vitamin B₁₂ deficiency in the central nervous system

Shao-Chiang Lai, Yasumi Nakayama, Jeffrey M. Sequeira, Bogdan J. Wlodarczyk, Robert M. Cabrera, Richard H. Finnell, Teodoro Bottiglieri, Edward V. Quadros

FASEB J. 2013 Jun; 27(6): 2468–2475. doi: 10.1096/fj.12-219055

PMCID:: PMC3659357

Abstract Article

Select item 343337016.

Vitamin B₁₂ deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse

Sílvia Fernàndez-Roig, Shao-Chiang Lai, Michelle M Murphy, Joan Fernandez-Ballart, Edward V Quadros

Nutr Metab (Lond) 2012; 9: 41. Published online 2012 May 18. doi: 10.1186/1743-7075-9-41

PMCID:: PMC3433370

Abstract Article PDF–182K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253418.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 261463219.

The protein and the gene encoding the receptor for the cellular uptake of transcobalamin-bound cobalamin

Edward V. Quadros, Yasumi Nakayama, Jeffrey M. Sequeira

Blood. 2009 Jan 1; 113(1): 186–192. Prepublished online 2008 Sep 8. doi: 10.1182/blood-2008-05-158949

PMCID:: PMC2614632

Abstract Article

Select item 258517220.

Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration

Sophia M Blake, Vera Strasser, Nuno Andrade, Sarah Duit, Reinhold Hofbauer, Wolfgang J Schneider, Johannes Nimpf

EMBO J. 2008 Nov 19; 27(22): 3069–3080. Published online 2008 Oct 23. doi: 10.1038/emboj.2008.223

Correction in:: EMBO J. 2008 Dec 17; 27(24): 3332.

PMCID:: PMC2585172

Abstract Article PDF–2.2M

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