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Items: 1 to 20 of 71

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Multi-omics analyses demonstrate a critical role for EHMT1 methyltransferase in transcriptional repression during oogenesis
Hannah Demond, Courtney W. Hanna, Juan Castillo-Fernandez, Fátima Santos, Evangelia K. Papachristou, Anne Segonds-Pichon, Kamal Kishore, Simon Andrews, Clive S. D'Santos, Gavin Kelsey
Genome Res. 2023 Jan; 33(1): 18–31. doi: 10.1101/gr.277046.122
PMCID:
PMC9977154
AbstractArticlePDF–5.9M
3.
Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models
Hamid Meziane, Marie-Christine Birling, Olivia Wendling, Sophie Leblanc, Aline Dubos, Mohammed Selloum, Guillaume Pavlovic, Tania Sorg, Vera M. Kalscheuer, Pierre Billuart, Frédéric Laumonnier, Jamel Chelly, Hans van Bokhoven, Yann Herault
Biomedicines. 2022 Dec; 10(12): 3148. Published online 2022 Dec 6. doi: 10.3390/biomedicines10123148
PMCID:
PMC9775489
AbstractArticlePDF–2.8M
4.
NRSF/REST lies at the intersection between epigenetic regulation, miRNA-mediated gene control and neurodevelopmental pathways associated with Intellectual disability (ID) and Schizophrenia
Mouhamed Alsaqati, Brittany A. Davis, Jamie Wood, Megan M. Jones, Lora Jones, Aishah Westwood, Olena Petter, Anthony R. Isles, David Linden, Marianne Van den Bree, Michael Owen, Jeremy Hall, Adrian J. Harwood
Transl Psychiatry. 2022; 12: 438. Published online 2022 Oct 10. doi: 10.1038/s41398-022-02199-z
PMCID:
PMC9551101
AbstractArticlePDF–2.9M
5.
Keap1 moderates the transcription of virus induced genes through G9a-GLP and NFκB p50 recruitment
Veronica Elizabeth Burns, Tom Klaus Kerppola
Immunology. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Immunology. 2022 Sep; 167(1): 105–121. Published online 2022 Jul 7. doi: 10.1111/imm.13527
PMCID:
PMC9378643
AbstractArticlePDF–3.2M
6.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
7.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
8.
Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra syndrome
Ayumi Yamada, Takae Hirasawa, Kayako Nishimura, Chikako Shimura, Naomi Kogo, Kei Fukuda, Madoka Kato, Masaki Yokomori, Tetsutaro Hayashi, Mana Umeda, Mika Yoshimura, Yoichiro Iwakura, Itoshi Nikaido, Shigeyoshi Itohara, Yoichi Shinkai
iScience. 2021 Jul 23; 24(7): 102741. Published online 2021 Jun 17. doi: 10.1016/j.isci.2021.102741
Correction in:
iScience. 2021 Nov 19; 24(11): 103253.
PMCID:
PMC8258976
AbstractArticlePDF–3.0M
9.
Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate
Ivana Bukova, Katarzyna Izabela Szczerkowska, Michaela Prochazkova, Inken M. Beck, Jan Prochazka, Radislav Sedlacek
Front Cell Dev Biol. 2021; 9: 620692. Published online 2021 Jun 2. doi: 10.3389/fcell.2021.620692
PMCID:
PMC8206640
AbstractArticlePDF–4.5M
10.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
11.
PRC2 and EHMT1 regulate H3K27me2 and H3K27me3 establishment across the zygote genome
Tie-Gang Meng, Qian Zhou, Xue-Shan Ma, Xiao-Yu Liu, Qing-Ren Meng, Xian-Ju Huang, Hong-Lin Liu, Wen-Long Lei, Zheng-Hui Zhao, Ying-Chun Ouyang, Yi Hou, Heide Schatten, Xiang-Hong Ou, Zhen-Bo Wang, Shao-Rong Gao, Qing-Yuan Sun
Nat Commun. 2020; 11: 6354. Published online 2020 Dec 11. doi: 10.1038/s41467-020-20242-9
PMCID:
PMC7733509
AbstractArticlePDF–3.3M
12.
Context-Dependent Requirement of Euchromatic Histone Methyltransferase Activity during Reprogramming to Pluripotency
Simon E. Vidal, Alexander Polyzos, Kaushiki Chatterjee, Ly-sha Ee, Emily Swanzey, Jorge Morales-Valencia, Hongsu Wang, Chaitanya N. Parikh, Bhishma Amlani, Shengjiang Tu, Yixiao Gong, Valentina Snetkova, Jane A. Skok, Aristotelis Tsirigos, Sangyong Kim, Effie Apostolou, Matthias Stadtfeld
Stem Cell Reports. 2020 Dec 8; 15(6): 1233–1245. Published online 2020 Sep 24. doi: 10.1016/j.stemcr.2020.08.011
PMCID:
PMC7724475
AbstractArticlePDF–2.1M
13.
EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas
Moritz Negwer, Karol Piera, Rick Hesen, Lukas Lütje, Lynn Aarts, Dirk Schubert, Nael Nadif Kasri
Brain Struct Funct. 2020; 225(9): 2701–2716. Published online 2020 Sep 25. doi: 10.1007/s00429-020-02149-9
PMCID:
PMC7674571
AbstractArticlePDF–1.9M
14.
Epigenetic response to environmental stress: Assembly of BRG1–G9a/GLP–DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts
Pei Han, Wei Li, Jin Yang, Ching Shang, Chiou-Hong Lin, Wei Cheng, Calvin T. Hang, Hsiu-Ling Cheng, Chen-Hao Chen, Johnson Wong, Yiqin Xiong, Mingming Zhao, Stavros G. Drakos, Andrea Ghetti, Dean Y. Li, Daniel Bernstein, Huei-sheng Vincent Chen, Thomas Quertermous, Ching-Pin Chang
Biochim Biophys Acta. Author manuscript; available in PMC 2020 Aug 3.
Published in final edited form as: Biochim Biophys Acta. 2016 Jul; 1863(7 Pt B): 1772–1781. Published online 2016 Mar 4. doi: 10.1016/j.bbamcr.2016.03.002
PMCID:
PMC7397641
AbstractArticlePDF–2.1M
15.
Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling
Monica Frega, Katrin Linda, Jason M. Keller, Güvem Gümüş-Akay, Britt Mossink, Jon-Ruben van Rhijn, Moritz Negwer, Teun Klein Gunnewiek, Katharina Foreman, Nine Kompier, Chantal Schoenmaker, Willem van den Akker, Ilse van der Werf, Astrid Oudakker, Huiqing Zhou, Tjitske Kleefstra, Dirk Schubert, Hans van Bokhoven, Nael Nadif Kasri
Nat Commun. 2019; 10: 4928. Published online 2019 Oct 30. doi: 10.1038/s41467-019-12947-3
PMCID:
PMC6821803
AbstractArticlePDF–3.1M
16.
CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I
Nathan Palmer, S. Zakiah A. Talib, Chandrahas Koumar Ratnacaram, Diana Low, Xavier Bisteau, Joanna Hui Si Lee, Elisabeth Pfeiffenberger, Heike Wollmann, Joel Heng Loong Tan, Sheena Wee, Radoslaw Sobota, Jayantha Gunaratne, Daniel M. Messerschmidt, Ernesto Guccione, Philipp Kaldis
J Cell Biol. 2019 Sep 2; 218(9): 2896–2918. Published online 2019 Jul 26. doi: 10.1083/jcb.201903125
PMCID:
PMC6719441
AbstractArticlePDF–3.7M
17.
Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome
Giovanni Iacono, Aline Dubos, Hamid Méziane, Marco Benevento, Ehsan Habibi, Amit Mandoli, Fabrice Riet, Mohammed Selloum, Robert Feil, Huiqing Zhou, Tjitske Kleefstra, Nael Nadif Kasri, Hans van Bokhoven, Yann Herault, Hendrik G Stunnenberg
Nucleic Acids Res. 2018 Jun 1; 46(10): 4950–4965. Published online 2018 Mar 15. doi: 10.1093/nar/gky196
PMCID:
PMC6007260
AbstractArticlePDF–5.2M
18.
G9a regulates temporal preimplantation developmental program and lineage segregation in blastocyst
Jan J Zylicz, Maud Borensztein, Frederick CK Wong, Yun Huang, Caroline Lee, Sabine Dietmann, M Azim Surani
eLife. 2018; 7: e33361. Published online 2018 May 10. doi: 10.7554/eLife.33361
PMCID:
PMC5959720
AbstractArticlePDF–2.7M
19.
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice
Jin Li, Su-Ping Deng, Gang Wei, Peng Yu
Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012
PMCID:
PMC5868181
AbstractArticlePDF–653K
20.
Repression of adipose tissue fibrosis through a PRDM16-GTF2IRD1 complex improves systemic glucose homeostasis
Yutaka Hasegawa, Kenji Ikeda, Yong Chen, Diana Alba, Daniel Stifler, Kosaku Shinoda, Takashi Hosono, Pema Maretich, Yangyu Yang, Yasushi Ishigaki, Jingyi Chi, Paul Cohen, Suneil Koliwad, Shingo Kajimura
Cell Metab. Author manuscript; available in PMC 2019 Jan 9.
Published in final edited form as: Cell Metab. 2018 Jan 9; 27(1): 180–194.e6. doi: 10.1016/j.cmet.2017.12.005
PMCID:
PMC5765755
AbstractArticlePDF–3.0M

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