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Select item 110821641.

BIN1 regulates actin-membrane interactions during IRSp53-dependent filopodia formation

Laura Picas, Charlotte André-Arpin, Franck Comunale, Hugo Bousquet, Feng-Ching Tsai, Félix Rico, Paolo Maiuri, Julien Pernier, Stéphane Bodin, Anne-Sophie Nicot, Jocelyn Laporte, Patricia Bassereau, Bruno Goud, Cécile Gauthier-Rouvière, Stéphanie Miserey

Commun Biol. 2024; 7: 549. Published online 2024 May 9. doi: 10.1038/s42003-024-06168-8

PMCID:: PMC11082164

Abstract Article PDF–7.4M

Select item 110325702.

BIN1^K358R suppresses glial response to plaques in mouse model of Alzheimer's disease

Laura Fernandez Garcia‐Agudo, Zechuan Shi, Ian F. Smith, Enikö A. Kramár, Katelynn Tran, Shimako Kawauchi, Shuling Wang, Sherilyn Collins, Amber Walker, Kai‐Xuan Shi, Jonathan Neumann, Heidi Yahan Liang, Celia Da Cunha, Giedre Milinkeviciute, Samuel Morabito, Emily Miyoshi, Narges Rezaie, Angela Gomez‐Arboledas, Adrian Mendoza Arvilla, Daryan Iman Ghaemi, Andrea J. Tenner, Frank M. LaFerla, Marcelo A. Wood, Ali Mortazavi, Vivek Swarup, Grant R. MacGregor, Kim N. Green

Alzheimers Dement. 2024 Apr; 20(4): 2922–2942. Published online 2024 Mar 9. doi: 10.1002/alz.13767

PMCID:: PMC11032570

Abstract Article PDF–5.6M

Select item 109168663.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 104961764.

APOE-ε4 and BIN1 increase risk of Alzheimer’s disease pathology but not specifically of Lewy body pathology

Seth Talyansky, Yann Le Guen, Nandita Kasireddy, Michael E. Belloy, Michael D. Greicius

Acta Neuropathol Commun. 2023; 11: 149. Published online 2023 Sep 12. doi: 10.1186/s40478-023-01626-6

PMCID:: PMC10496176

Abstract Article PDF–3.1M

Select item 104958855.

High Indoleamine 2,3-Dioxygenase Expression along with Low Bridging Integrator-1 Expression in Hepatocellular Carcinoma Patients

Kashif Asghar, Iftikhar Ali Rana, Muhammad Abu Bakar, Kinza Hasham, Muhammad Tahseen, Sundus Bilal, Shafqat Mehmood, Asim Farooq, Kashif Siddique, Asif Loya

Asian Pac J Cancer Prev. 2023; 24(5): 1591–1600. doi: 10.31557/APJCP.2023.24.5.1591

PMCID:: PMC10495885

Abstract Article PDF–1.0M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101516157.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 99786358.

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons

Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson

J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888

PMCID:: PMC9978635

Abstract Article PDF–10M

Select item 95925859.

Genetic polymorphism in BIN1 rather than APOE is associated with poor recognition memory among men without dementia

Kanika Mehta, Mohammadreza Mohebbi, Julie A. Pasco, Lana J. Williams, Ken Walder, Boon Lung Ng, Veer Bala Gupta

Sci Rep. 2022; 12: 17802. Published online 2022 Oct 24. doi: 10.1038/s41598-022-20587-9

PMCID:: PMC9592585

Abstract Article PDF–1.1M

Select item 945037410.

Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1

Jiewei Lin, Xinjing Wang, Shuyu Zhai, Minmin Shi, Chenghong Peng, Xiaxing Deng, Da Fu, Jiancheng Wang, Baiyong Shen

J Hematol Oncol. 2022; 15: 128. Published online 2022 Sep 6. doi: 10.1186/s13045-022-01348-7

PMCID:: PMC9450374

Abstract Article PDF–10M

Select item 934857611.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 927928512.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973613.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 907787414.

BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia

Ari Sudwarts, Supriya Ramesha, Tianwen Gao, Moorthi Ponnusamy, Shuai Wang, Mitchell Hansen, Alena Kozlova, Sara Bitarafan, Prateek Kumar, David Beaulieu-Abdelahad, Xiaolin Zhang, Lisa Collier, Charles Szekeres, Levi B. Wood, Jubao Duan, Gopal Thinakaran, Srikant Rangaraju

Mol Neurodegener. 2022; 17: 33. Published online 2022 May 7. doi: 10.1186/s13024-022-00535-x

PMCID:: PMC9077874

Abstract Article PDF–8.1M

Select item 895155615.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 890996516.

Epigenetic Studies in the Male APP/BIN1/COPS5 Triple-Transgenic Mouse Model of Alzheimer’s Disease

Olaia Martínez-Iglesias, Vinogran Naidoo, Iván Carrera, Ramón Cacabelos

Int J Mol Sci. 2022 Mar; 23(5): 2446. Published online 2022 Feb 23. doi: 10.3390/ijms23052446

PMCID:: PMC8909965

Abstract Article PDF–3.4M

Select item 889447417.

The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner

Raja Bhattacharyya, Catarina Amelia Fidalgo Teves, Alexandra Long, Madison Hofert, Rudolph E. Tanzi

Sci Rep. 2022; 12: 3486. Published online 2022 Mar 3. doi: 10.1038/s41598-022-07372-4

Correction in:: Sci Rep. 2022; 12: 5739.

PMCID:: PMC8894474

Abstract Article PDF–4.7M

Select item 889236518.

BIN1 modulation in vivo rescues dynamin-related myopathy

Valentina Maria Lionello, Christine Kretz, Evelina Edelweiss, Corinne Crucifix, Raquel Gómez-Oca, Nadia Messaddeq, Suzie Buono, Pascale Koebel, Xènia Massana Muñoz, Nadège Diedhiou, Belinda S. Cowling, Marc Bitoun, Jocelyn Laporte

Proc Natl Acad Sci U S A. 2022 Mar 1; 119(9): e2109576119. Published online 2022 Feb 25. doi: 10.1073/pnas.2109576119

PMCID:: PMC8892365

Abstract Article PDF–2.6M

Select item 852757819.

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity

Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang

Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008

PMCID:: PMC8527578

Abstract Article PDF–4.5M

Select item 841389420.

Alzheimer's disease BIN1 coding variants increase intracellular Aβ levels by interfering with BACE1 recycling

Catarina Perdigão, Mariana A. Barata, Tatiana Burrinha, Cláudia Guimas Almeida

J Biol Chem. 2021 Sep; 297(3): 101056. Published online 2021 Aug 8. doi: 10.1016/j.jbc.2021.101056

PMCID:: PMC8413894

Abstract Article PDF–3.9M

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