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Items: 1 to 20 of 406

1.
Plasma-Derived Extracellular Vesicles and Non-Extracellular Vesicle Components from APCMin/+ Mice Promote Pro-Tumorigenic Activities and Activate Human Colonic Fibroblasts via the NF-κB Signaling Pathway
Luis A. Arteaga-Blanco, Andrew E. Evans, Dan A. Dixon
Cells. 2024 Jul; 13(14): 1195. Published online 2024 Jul 15. doi: 10.3390/cells13141195
PMCID:
PMC11274984
AbstractArticlePDF–7.0M
2.
Bcl-2 Up-Regulation Mediates Taxane Resistance Downstream of APC Loss
Angelique R. Wise, Sara Maloney, Adam Hering, Sarah Zabala, Grace E. Richmond, Monica K. VanKlompenberg, Murlidharan T. Nair, Jenifer R. Prosperi
Int J Mol Sci. 2024 Jun; 25(12): 6745. Published online 2024 Jun 19. doi: 10.3390/ijms25126745
PMCID:
PMC11203545
AbstractArticlePDF–1.5M
3.
A nonsense mutation in exon 8 of the APC gene (Arg283Ter) causes clinically variable FAP in a Malaysian Chinese family
Zulqarnain Mohamed, Rahimah Ahmad, Ng Sau Yoke, Zubaidah Zakaria, Harun Ahmad, Tong Hung Yew
Cancer Sci. 2003 Aug; 94(8): 725–728. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01509.x
PMCID:
PMC11159997
AbstractArticlePDF–124K
4.
APC promoter hypermethylation is an early event in endometrial tumorigenesis
Atanas Ignatov, Joachim Bischoff, Tanja Ignatov, Christa Schwarzenau, Thomas Krebs, Doerthe Kuester, Serban D. Costa, Albert Roessner, Andrzej Semczuk, Regine Schneider‐Stock
Cancer Sci. 2010 Feb; 101(2): 321–327. Published online 2009 Oct 12. doi: 10.1111/j.1349-7006.2009.01397.x
PMCID:
PMC11158934
AbstractArticlePDF–317K
5.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
6.
β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53
Mohamed Bourmoum, Nikolina Radulovich, Amit Sharma, Johnny M. Tkach, Ming-Sound Tsao, Laurence Pelletier
PLoS One. 2024; 19(2): e0295030. Published online 2024 Feb 7. doi: 10.1371/journal.pone.0295030
PMCID:
PMC10849215
AbstractArticlePDF–2.1M
7.
APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation
Dan Zhang, Qi-Qi Ni, Shu-Yang Wang, Wen-Feng He, Ze-Xuan Hong, Hui-Ye Liu, Xiao-Hong Chen, Li-Jie Chen, Fang-Yi Han, Ling-Jie Zhang, Xiao-ming Li, Yan-qing Ding, Hong-li Jiao, Ya-ping Ye
Cell Mol Life Sci. 2024 Dec; 81(1): 57. Published online 2024 Jan 27. doi: 10.1007/s00018-023-05068-0
PMCID:
PMC10817841
AbstractArticlePDF–6.2M
8.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
9.
APC ameliorates idiopathic membranous nephropathy by affecting podocyte apoptosis through the ERK1/2/YB-1/PLA2R1 axis
Ben Ke, Wen Shen, Yunfei Liao, Jing Hu, Weiping Tu, Xiangdong Fang
Mol Cell Biochem. 2023; 478(9): 1999–2011. Published online 2023 Jan 2. doi: 10.1007/s11010-022-04650-7
PMCID:
PMC10359206
AbstractArticlePDF–7.9M
10.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
11.
Let‐7b‐5p inhibits colon cancer progression by prohibiting APC ubiquitination degradation and the Wnt pathway by targeting NKD1
Yuyang Dai, Jinsong Liu, Xuyan Li, Jianzhong Deng, Cheng Zeng, Wenbin Lu, Yongzhong Hou, Ying Sheng, Honglin Wu, Qian Liu
Cancer Sci. 2023 May; 114(5): 1882–1897. Published online 2022 Dec 9. doi: 10.1111/cas.15678
Correction in:
Cancer Sci. 2023 Aug; 114(8): 3466–3469.
PMCID:
PMC10154867
AbstractArticlePDF–30M
12.
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
Greta Pintacuda, Yu-Han H. Hsu, Kalliopi Tsafou, Ka Wan Li, Jacqueline M. Martín, Jackson Riseman, Julia C. Biagini, Joshua K.T. Ching, Daya Mena, Miguel A. Gonzalez-Lozano, Shawn B. Egri, Jake Jaffe, August B. Smit, Nadine Fornelos, Kevin C. Eggan, Kasper Lage
Cell Genom. 2023 Mar 8; 3(3): 100250. Published online 2023 Jan 24. doi: 10.1016/j.xgen.2022.100250
PMCID:
PMC10025425
AbstractArticlePDF–22M
13.
Rare Genetic Variants in Human APC Are Implicated in Mesiodens and Isolated Supernumerary Teeth
Chomchanok Panyarat, Siriruk Nakornchai, Kanoknart Chintakanon, Niramol Leelaadisorn, Worrachet Intachai, Bjorn Olsen, Sissades Tongsima, Ploy Adisornkanj, Chumpol Ngamphiw, Timothy C. Cox, Piranit Kantaputra
Int J Mol Sci. 2023 Mar; 24(5): 4255. Published online 2023 Feb 21. doi: 10.3390/ijms24054255
PMCID:
PMC10002335
AbstractArticlePDF–3.3M
14.
Interactomes of Glycogen Synthase Kinase-3 Isoforms
Kevin W. Cormier, Brett Larsen, Anne-Claude Gingras, James R. Woodgett
J Proteome Res. 2023 Mar 3; 22(3): 977–989. Published online 2023 Feb 13. doi: 10.1021/acs.jproteome.2c00825
PMCID:
PMC9990120
AbstractArticlePDF–3.7M
15.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
16.
The Mutation Spectrum and Two Novel Point Mutations in the APC Gene in Vietnamese Patients with Familial Adenomatous Polyposis
Bac Hoang Nguyen, Suong Thi Bang Nguyen, Huy Huu Nguyen, Tin Trung Nguyen, Khoi Minh Le
Asian Pac J Cancer Prev. 2022 May; 23(5): 1517–1522. doi: 10.31557/APJCP.2022.23.5.1517
PMCID:
PMC9587892
AbstractArticlePDF–1.3M
17.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
18.
Constitutional chromothripsis of the APC locus as a cause of genetic predisposition to colon cancer
Florentine Scharf, Rafaela Magalhaes Leal Silva, Monika Morak, Alex Hastie, Julia M A Pickl, Kai Sendelbach, Christian Gebhard, Melanie Locher, Andreas Laner, Verena Steinke-Lange, Udo Koehler, Elke Holinski-Feder, Dieter A Wolf
J Med Genet. 2022 Oct; 59(10): 976–983. Published online 2021 Dec 14. doi: 10.1136/jmedgenet-2021-108147
PMCID:
PMC9554066
AbstractArticlePDF–1.7M
19.
CDH1、FANCB和APC基因多态性与中国人群肺癌易感性的关系
苏 联椿, 黄 华, 高 敏, 李 永文, 施 睿峰, 陈 琛, 李 宣广, 朱 光胜, 刘 红雨, 陈 军
Zhongguo Fei Ai Za Zhi. 2022 Sep 20; 25(9): 658–664. Chinese. doi: 10.3779/j.issn.1009-3419.2022.102.21
PMCID:
PMC9549421
AbstractArticlePDF–1.9M
20.
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1
Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin
J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379
PMCID:
PMC9513271
AbstractArticlePDF–2.7M

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