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Select item 112417901.

The integrin receptor beta₇ subunit mediates airway remodeling and hyperresponsiveness in allergen exposed mice

Miri Assayag, Tahrir Obedeyah, Avraham Abutbul, Neville Berkman

Respir Res. 2024; 25: 273. Published online 2024 Jul 12. doi: 10.1186/s12931-024-02899-8

PMCID:: PMC11241790

Abstract Article PDF–2.0M

Select item 112146302.

The protective roles of integrin α4β7 and Amphiregulin-expressing innate lymphoid cells in lupus nephritis

Seungwon Ryu, Kyung Ah Kim, Jinwoo Kim, Dong Hun Lee, Yong-Soo Bae, Hajeong Lee, Byoung Choul Kim, Hye Young Kim

Cell Mol Immunol. 2024 Jul; 21(7): 723–737. Published online 2024 May 28. doi: 10.1038/s41423-024-01178-2

PMCID:: PMC11214630

Abstract Article PDF–6.5M

Select item 105924723.

Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow

Yuji Kamioka, Yoshihiro Ueda, Naoyuki Kondo, Keizo Tokuhiro, Yoshiki Ikeda, Wolfgang Bergmeier, Tatsuo Kinashi

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112580. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112580

PMCID:: PMC10592472

Abstract Article PDF–2.2M

Select item 87322644.

Antibody secreting cells are critically dependent on integrin α4β7/MAdCAM-1 for intestinal recruitment and control of the microbiota during chronic colitis

Christopher J. Tyler, Mauricio Guzman, Luke R. Lundborg, Shaila Yeasmin, Nadia Zgajnar, Paul Jedlicka, Giorgos Bamias, Jesús Rivera-Nieves

Mucosal Immunol. 2022; 15(1): 109–119. Published online 2021 Aug 25. doi: 10.1038/s41385-021-00445-z

PMCID:: PMC8732264

Abstract Article PDF–6.3M

Select item 85287145.

An integrin αEβ7-dependent mechanism of IgA transcytosis requires direct plasma cell contact with intestinal epithelium

Mauricio Guzman, Luke R. Lundborg, Shaila Yeasmin, Christopher J. Tyler, Nadia R. Zgajnar, Vanessa Taupin, Katarzyna Dobaczewska, Zbigniew Mikulski, Giorgos Bamias, Jesús Rivera-Nieves

Mucosal Immunol. 2021; 14(6): 1347–1357. Published online 2021 Aug 20. doi: 10.1038/s41385-021-00439-x

PMCID:: PMC8528714

Abstract Article PDF–5.4M

Select item 83853266.

Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease

Bingbing Dai, Jason A. Hackney, Ryan Ichikawa, Allen Nguyen, Justin Elstrott, Luz D. Orozco, Kai-Hui Sun, Zora Modrusan, Alvin Gogineni, Alexis Scherl, John Gubatan, Aida Habtezion, Monika Deswal, Ma Somsouk, William A. Faubion, Akiko Chai, Zaineb Sharafali, Azra Hassanali, Young S. Oh, Swati Tole, Jacqueline McBride, Mary E. Keir, Tangsheng Yi

Cell Rep Med. 2021 Aug 17; 2(8): 100381. Published online 2021 Aug 17. doi: 10.1016/j.xcrm.2021.100381

PMCID:: PMC8385326

Abstract Article PDF–4.3M

Select item 82995667.

Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity

Laura Mathä, Mónica Romera-Hernández, Catherine A. Steer, Yi Han Yin, Mona Orangi, Hanjoo Shim, ChihKai Chang, Fabio M. Rossi, Fumio Takei

Front Immunol. 2021; 12: 679509. Published online 2021 Jul 9. doi: 10.3389/fimmu.2021.679509

PMCID:: PMC8299566

Abstract Article PDF–5.3M

Select item 82062868.

Binding of HIV-1 virions to α₄β₇ expressing cells and impact of antagonizing α₄β₇ on HIV-1 infection of primary CD4⁺ T cells

Chang Li, Wei Jin, Tao Du, Biao Wu, Yalan Liu, Robin J. Shattock, Qinxue Hu

Virol Sin. 2014 Dec; 29(6): 381–392. Published online 2014 Dec 10. doi: 10.1007/s12250-014-3525-8

Correction in:: Virol Sin. 2015 Apr; 30(2): 162.

PMCID:: PMC8206286

Abstract Article PDF–2.4M

Select item 80536999.

MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice

Angela Schippers, Jessica Hübel, Felix Heymann, Thomas Clahsen, Sreepradha Eswaran, Sarah Schlepütz, Robin Püllen, Nikolaus Gaßler, Klaus Tenbrock, Frank Tacke, Norbert Wagner

Cell Mol Gastroenterol Hepatol. 2021; 11(4): 1227–1250.e1. Published online 2020 Dec 13. doi: 10.1016/j.jcmgh.2020.12.003

PMCID:: PMC8053699

Abstract Article PDF–6.8M

Select item 723932810.

T Cell Recruitment to the Intestinal Stem Cell Compartment Drives Immune-Mediated Intestinal Damage after Allogeneic Transplantation

Ya-Yuan Fu, Anastasiya Egorova, Catherine Sobieski, Jason Kuttiyara, Marco Calafiore, Shuichiro Takashima, Hans Clevers, Alan M. Hanash

Immunity. Author manuscript; available in PMC 2020 Jul 16.

Published in final edited form as: Immunity. 2019 Jul 16; 51(1): 90–103.e3. Published online 2019 Jul 2. doi: 10.1016/j.immuni.2019.06.003

PMCID:: PMC7239328

Abstract Article PDF–3.3M

Select item 701600011.

β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25^hiFoxP3⁺ Regulatory T Cells

Hao Sun, Wun Kuk, Jesús Rivera-Nieves, Miguel Alejandro Lopez-Ramirez, Lars Eckmann, Mark H. Ginsberg

Cell Mol Gastroenterol Hepatol. 2020; 9(3): 369–385. Published online 2019 Nov 9. doi: 10.1016/j.jcmgh.2019.10.012

PMCID:: PMC7016000

Abstract Article PDF–2.8M

Select item 678740512.

The Compromised Mucosal Immune System of β7 Integrin-Deficient Mice Has Only Minor Effects on the Fecal Microbiota in Homeostasis

Anshu Babbar, Thomas C. A. Hitch, Oliver Pabst, Thomas Clavel, Jessica Hübel, Sreepradha Eswaran, Norbert Wagner, Angela Schippers

Front Microbiol. 2019; 10: 2284. Published online 2019 Oct 4. doi: 10.3389/fmicb.2019.02284

PMCID:: PMC6787405

Abstract Article PDF–1.9M

Select item 674065013.

Integrin Requirement for Hippocampal Synaptic Plasticity and Spatial Memory

Chi-Shing Chan, Edwin J. Weeber, Sindhu Kurup, J. David Sweatt, Ronald L. Davis

J Neurosci. 2003 Aug 6; 23(18): 7107–7116. doi: 10.1523/JNEUROSCI.23-18-07107.2003

PMCID:: PMC6740650

Abstract Article PDF–858K

Select item 664221514.

Inflammation triggers immediate rather than progressive changes in monocyte differentiation in the small intestine

Girmay Desalegn, Oliver Pabst

Nat Commun. 2019; 10: 3229. Published online 2019 Jul 19. doi: 10.1038/s41467-019-11148-2

PMCID:: PMC6642215

Abstract Article PDF–2.5M

Select item 653132215.

Mechanical skin injury promotes food anaphylaxis by driving intestinal mast cell expansion.

Juan-Manuel Leyva-Castillo, Claire Galand, Christy Kam, Oliver Burton, Michael Gurish, Melissa A. Musser, Jeffrey D. Goldsmith, Elizabeth Hait, Samuel Nurko, Frank Brombacher, Chen Dong, Fred D. Finkelman, Richard T. Lee, Steven Ziegler, Isaac Chiu, K. Frank Austen, Raif S. Geha

Immunity. Author manuscript; available in PMC 2020 May 21.

Published in final edited form as: Immunity. 2019 May 21; 50(5): 1262–1275.e4. Published online 2019 Apr 23. doi: 10.1016/j.immuni.2019.03.023

PMCID:: PMC6531322

Abstract Article PDF–2.2M

Select item 636702316.

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease

Shun He, Florian Kahles, Sara Rattik, Manfred Nairz, Cameron S. McAlpine, Atsushi Anzai, Daniel Selgrade, Ashley M. Fenn, Christopher T. Chan, John E. Mindur, Colin Valet, Wolfram C. Poller, Lennard Halle, Noemi Rotllan, Yoshiko Iwamoto, Gregory R. Wojtkiewicz, Ralph Weissleder, Peter Libby, Carlos Fernández-Hernando, Daniel J. Drucker, Matthias Nahrendorf, Filip K. Swirski

Nature. Author manuscript; available in PMC 2019 Jul 30.

Published in final edited form as: Nature. 2019 Feb; 566(7742): 115–119. Published online 2019 Jan 30. doi: 10.1038/s41586-018-0849-9