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Select item 108418131.

IntS6 and the Integrator phosphatase module tune the efficiency of select premature transcription termination events

Rina Fujiwara, Si-Nan Zhai, Dongming Liang, Aayushi P. Shah, Matthew Tracey, Xu-Kai Ma, Christopher J. Fields, María Saraí Mendoza-Figueroa, Michele C. Meline, Deirdre C. Tatomer, Li Yang, Jeremy E. Wilusz

Mol Cell. Author manuscript; available in PMC 2024 Dec 21.

Published in final edited form as: Mol Cell. 2023 Dec 21; 83(24): 4445–4460.e7. Published online 2023 Nov 22. doi: 10.1016/j.molcel.2023.10.035

PMCID:: PMC10841813

Abstract Article PDF–3.4M

Select item 94511592.

Variant Polycomb complexes in Drosophila consistent with ancient functional diversity

Hyuckjoon Kang, Janel R. Cabrera, Barry M. Zee, Heather A. Kang, Jenny Marie Jobe, Maeve B. Hegarty, Aurelie E. Barry, Alexander Glotov, Yuri B. Schwartz, Mitzi I. Kuroda

Sci Adv. 2022 Sep; 8(36): eadd0103. Published online 2022 Sep 7. doi: 10.1126/sciadv.add0103

PMCID:: PMC9451159

Abstract Article PDF–1.3M

Select item 76609703.

Integrator Recruits Protein Phosphatase 2A to Prevent Pause Release and Facilitate Transcription Termination

Kai-Lieh Huang, David Jee, Chad B. Stein, Nathan D. Elrod, Telmo Henriques, Lauren G. Mascibroda, David Baillat, William K. Russell, Karen Adelman, Eric J. Wagner

Mol Cell. Author manuscript; available in PMC 2021 Oct 15.

Published in final edited form as: Mol Cell. 2020 Oct 15; 80(2): 345–358.e9. Published online 2020 Sep 22. doi: 10.1016/j.molcel.2020.08.016

PMCID:: PMC7660970

Abstract Article PDF–3.3M

Select item 69615784.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 68244655.

The Integrator complex cleaves nascent mRNAs to attenuate transcription

Deirdre C. Tatomer, Nathan D. Elrod, Dongming Liang, Mei-Sheng Xiao, Jeffrey Z. Jiang, Michael Jonathan, Kai-Lieh Huang, Eric J. Wagner, Sara Cherry, Jeremy E. Wilusz

Genes Dev. 2019 Nov 1; 33(21-22): 1525–1538. doi: 10.1101/gad.330167.119

PMCID:: PMC6824465

Abstract Article PDF–4.0M

Select item 59346446.

Integrator subunit 4 is a ‘Symplekin-like’ scaffold that associates with INTS9/11 to form the Integrator cleavage module

Todd R Albrecht, Sergey P Shevtsov, Yixuan Wu, Lauren G Mascibroda, Natoya J Peart, Kai-Lieh Huang, Iain A Sawyer, Liang Tong, Miroslav Dundr, Eric J Wagner

Nucleic Acids Res. 2018 May 4; 46(8): 4241–4255. Published online 2018 Feb 20. doi: 10.1093/nar/gky100

PMCID:: PMC5934644

Abstract Article PDF–9.0M

Select item 57078057.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890028.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 48896589.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 483189110.

A genetic interaction map of cell cycle regulators

Maximilian Billmann, Thomas Horn, Bernd Fischer, Thomas Sandmann, Wolfgang Huber, Michael Boutros

Mol Biol Cell. 2016 Apr 15; 27(8): 1397–1407. doi: 10.1091/mbc.E15-07-0467

PMCID:: PMC4831891

Abstract Article PDF–4.0M

Select item 473800511.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 456802512.

Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions

Albert J. Erives

Dev Genes Evol. 2015; 225(5): 259–273. Published online 2015 Jul 15. doi: 10.1007/s00427-015-0508-1

PMCID:: PMC4568025

Abstract Article PDF–2.8M

Select item 452833013.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832914.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 443630315.

Genome-Wide Association Analyses Point to Candidate Genes for Electric Shock Avoidance in Drosophila melanogaster

Mirjam Appel, Claus-Jürgen Scholz, Tobias Müller, Marcus Dittrich, Christian König, Marie Bockstaller, Tuba Oguz, Afshin Khalili, Emmanuel Antwi-Adjei, Tamas Schauer, Carla Margulies, Hiromu Tanimoto, Ayse Yarali

PLoS One. 2015; 10(5): e0126986. Published online 2015 May 18. doi: 10.1371/journal.pone.0126986

PMCID:: PMC4436303

Abstract Article PDF–939K

Select item 435288716.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114