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Select item 107439771.

ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Common ISRE-Containing ISGs

Hanna Nowicka, Agata Sekrecka, Katarzyna Blaszczyk, Katarzyna Kluzek, Chan-Yu Chang, Joanna Wesoly, Chien-Kuo Lee, Hans A. R. Bluyssen

Int J Mol Sci. 2023 Dec; 24(24): 17635. Published online 2023 Dec 18. doi: 10.3390/ijms242417635

PMCID:: PMC10743977

Abstract Article PDF–8.9M

Select item 106156652.

Twist1/IRF9 interaction necessary for Interferon Stimulated Genes anti-ZIKA viral infection

Yuan You, Esteban Grasso, Ayesha Alvero, Jennifer Condon, Tanya Dimova, Anna Hu, Jiahui Ding, Marina Alexandrova, Diana Manchorova, Violeta Dimitrova, Aihua Liao, Gil Mor

J Immunol. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: J Immunol. 2023 Jun 15; 210(12): 1899–1912. doi: 10.4049/jimmunol.2300081

PMCID:: PMC10615665

Abstract Article PDF–3.1M

Select item 101079443.

Evolution and emergence of primate‐specific interferon regulatory factor 9

Sam Drury, Grace Claussen, Allison Zetterman, Hideaki Moriyama, Etsuko N. Moriyama, Luwen Zhang

J Med Virol. 2023 Feb; 95(2): e28521. Published online 2023 Jan 31. doi: 10.1002/jmv.28521

PMCID:: PMC10107944

Abstract Article PDF–3.7M

Select item 96508004.

Positive selection-driven fixation of a hominin-specific amino acid mutation related to dephosphorylation in IRF9

Jianhai Chen, Xuefei He, Ivan Jakovlić

BMC Ecol Evol. 2022; 22: 132. Published online 2022 Nov 10. doi: 10.1186/s12862-022-02088-5

PMCID:: PMC9650800

Abstract Article PDF–2.0M

Select item 94849445.

IRF9 and XAF1 as Diagnostic Markers of Primary Sjogren Syndrome

Lu Xiao, Zhou Yang, Shudian Lin

Comput Math Methods Med. 2022; 2022: 1867321. Published online 2022 Sep 12. doi: 10.1155/2022/1867321

PMCID:: PMC9484944

Abstract Article PDF–3.1M

Select item 94364776.

SCD2-mediated cooperative activation of IRF3-IRF9 regulatory circuit controls type I interferon transcriptome in CD4⁺ T cells

Toshio Kanno, Keisuke Miyako, Takahiro Nakajima, Satoru Yokoyama, Shigemi Sasamoto, Hikari K. Asou, Osamu Ohara, Toshinori Nakayama, Yusuke Endo

Front Immunol. 2022; 13: 904875. Published online 2022 Aug 18. doi: 10.3389/fimmu.2022.904875

PMCID:: PMC9436477

Abstract Article PDF–3.1M

Select item 92792857.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 88288958.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 87487899.

Systematic identification of NF90 target RNAs by iCLIP analysis

Valeria Lodde, Matteo Floris, Rachel Munk, Jennifer L. Martindale, Davide Piredda, Catello Mario Panu Napodano, Francesco Cucca, Sergio Uzzau, Kotb Abdelmohsen, Myriam Gorospe, Ji Heon Noh, M. Laura Idda

Sci Rep. 2022; 12: 364. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04101-1

PMCID:: PMC8748789

Abstract Article PDF–4.2M

Select item 816503010.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807964311.

SARS-CoV-2 Spike Targets USP33-IRF9 Axis via Exosomal miR-148a to Activate Human Microglia

Ritu Mishra, Akhil C. Banerjea

Front Immunol. 2021; 12: 656700. Published online 2021 Apr 14. doi: 10.3389/fimmu.2021.656700

PMCID:: PMC8079643

Abstract Article PDF–7.9M

Select item 800904812.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 743181013.

The Measles Virus V Protein Binding Site to STAT2 Overlaps That of IRF9

Yuma Nagano, Aoi Sugiyama, Madoka Kimoto, Takuya Wakahara, Yasuyo Noguchi, Xinxin Jiang, Shinya Saijo, Nobutaka Shimizu, Nana Yabuno, Min Yao, Paul R. Gooley, Gregory W. Moseley, Takashi Tadokoro, Katsumi Maenaka, Toyoyuki Ose

J Virol. 2020 Sep; 94(17): e01169-20. Prepublished online 2020 Jun 24. Published online 2020 Aug 17. doi: 10.1128/JVI.01169-20

PMCID:: PMC7431810

Abstract Article PDF–2.7M

Select item 732206714.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 634578115.

STAT3 is activated in multicellular spheroids of colon carcinoma cells and mediates expression of IRF9 and interferon stimulated genes

Elin Edsbäcker, Jason T. Serviss, Iryna Kolosenko, Caroline Palm-Apergi, Angelo De Milito, Katja Pokrovskaja Tamm

Sci Rep. 2019; 9: 536. Published online 2019 Jan 24. doi: 10.1038/s41598-018-37294-z

PMCID:: PMC6345781

Abstract Article PDF–2.2M

Select item 623402916.

Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer

Lili Liao, Zongzhi Z Liu, Lauren Langbein, Weijia Cai, Eun-Ah Cho, Jie Na, Xiaohua Niu, Wei Jiang, Zhijiu Zhong, Wesley L Cai, Geetha Jagannathan, Essel Dulaimi, Joseph R Testa, Robert G Uzzo, Yuxin Wang, George R Stark, Jianxin Sun, Stephen Peiper, Yaomin Xu, Qin Yan, Haifeng Yang

eLife. 2018; 7: e37925. Published online 2018 Oct 25. doi: 10.7554/eLife.37925

Correction in:: eLife. 2021; 10: e69256.

PMCID:: PMC6234029

Abstract Article PDF–8.4M

Select item 617016817.

Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency

Nicholas Hernandez, Isabelle Melki, Huie Jing, Tanwir Habib, Susie S.Y. Huang, Jeffrey Danielson, Tomasz Kula, Scott Drutman, Serkan Belkaya, Vimel Rattina, Lazaro Lorenzo-Diaz, Anais Boulai, Yoann Rose, Naoki Kitabayashi, Mathieu P. Rodero, Cecile Dumaine, Stéphane Blanche, Marie-Noëlle Lebras, Man Chun Leung, Lisa Sara Mathew, Bertrand Boisson, Shen-Ying Zhang, Stephanie Boisson-Dupuis, Silvia Giliani, Damien Chaussabel, Luigi D. Notarangelo, Stephen J. Elledge, Michael J. Ciancanelli, Laurent Abel, Qian Zhang, Nico Marr, Yanick J. Crow, Helen C. Su, Jean-Laurent Casanova

J Exp Med. 2018 Oct 1; 215(10): 2567–2585. doi: 10.1084/jem.20180628

PMCID:: PMC6170168

Abstract Article PDF–3.1M

Select item 609597718.

Interferon Regulatory Factor 9 Structure and Regulation

Alvin Paul, Thean Hock Tang, Siew Kit Ng

Front Immunol. 2018; 9: 1831. Published online 2018 Aug 10. doi: 10.3389/fimmu.2018.01831

PMCID:: PMC6095977

Abstract Article PDF–976K

Select item 589943519.

IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression

Jing Nan, Yuxin Wang, Jinbo Yang, George R. Stark

Proc Natl Acad Sci U S A. 2018 Apr 10; 115(15): 3906–3911. Published online 2018 Mar 26. doi: 10.1073/pnas.1714102115

PMCID:: PMC5899435

Abstract Article PDF–980K

Select item 578995220.

Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function

Srinivasan Rengachari, Silvia Groiss, Juliette M. Devos, Elise Caron, Nathalie Grandvaux, Daniel Panne

Proc Natl Acad Sci U S A. 2018 Jan 23; 115(4): E601–E609. Published online 2018 Jan 9. doi: 10.1073/pnas.1718426115

PMCID:: PMC5789952

Abstract Article PDF–2.1M

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