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Items: 1 to 20 of 304

1.
The involvement of HDAC3 in the pathogenesis of lung injury and pulmonary fibrosis
Hanming Yu, Shi Liu, Shuo Wang, Xiu Gu
Front Immunol. 2024; 15: 1392145. Published online 2024 Sep 26. doi: 10.3389/fimmu.2024.1392145
PMCID:
PMC11464298
AbstractArticlePDF–1.6M
2.
De novo missense variants in HDAC3 leading to epigenetic machinery dysfunction are associated with a variable neurodevelopmental disorder
Jihoon G. Yoon, Seong-Kyun Lim, Hoseok Seo, Seungbok Lee, Jaeso Cho, Soo Yeon Kim, Hyun Yong Koh, Annapurna H. Poduri, Vijayalakshmi Ramakumaran, Pradeep Vasudevan, Martijn J. de Groot, Jung Min Ko, Dohyun Han, Jong-Hee Chae, Chul-Hwan Lee
Am J Hum Genet. 2024 Aug 8; 111(8): 1588–1604. Published online 2024 Jul 23. doi: 10.1016/j.ajhg.2024.06.015
PMCID:
PMC11339613
AbstractArticlePDF–4.9M
3.
NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance
Hengxing Chen, Yun Li, Huafu Li, Xiancong Chen, Huafeng Fu, Deli Mao, Wei Chen, Linxiang Lan, Chunming Wang, Kaishun Hu, Jia Li, Chengming Zhu, Ian Evans, Eddie Cheung, Daning Lu, Yulong He, Axel Behrens, Dong Yin, Changhua Zhang
Nature. 2024; 631(8021): 663–669. Published online 2024 Jul 3. doi: 10.1038/s41586-024-07620-9
PMCID:
PMC11254748
AbstractArticlePDF–17M
4.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
5.
N-Acetylgalactosamine-4-sulfatase (Arylsulfatase B) Regulates PD-L1 Expression in Melanoma by an HDAC3-Mediated Epigenetic Mechanism
Sumit Bhattacharyya, InSug O-Sullivan, Joanne K. Tobacman
Int J Mol Sci. 2024 Jun; 25(11): 5851. Published online 2024 May 28. doi: 10.3390/ijms25115851
PMCID:
PMC11172302
AbstractArticlePDF–2.9M
6.
Matrix stiffening promotes chondrocyte senescence and the osteoarthritis development through downregulating HDAC3
Bowen Fu, Jianlin Shen, Xuenong Zou, Nian Sun, Ze Zhang, Zengping Liu, Canjun Zeng, Huan Liu, Wenhua Huang
Bone Res. 2024; 12: 32. Published online 2024 May 24. doi: 10.1038/s41413-024-00333-9
PMCID:
PMC11126418
AbstractArticlePDF–4.0M
7.
Gut microbial metabolite targets HDAC3-FOXK1-interferon axis in fibroblast-like synoviocytes to ameliorate rheumatoid arthritis
Hongzhen Chen, Xuekun Fu, Xiaohao Wu, Junyi Zhao, Fang Qiu, Zhenghong Wang, Zhuqian Wang, Xinxin Chen, Duoli Xie, Jie Huang, Junyu Fan, Xu Yang, Yi Song, Jie Li, Dongyi He, Guozhi Xiao, Aiping Lu, Chao Liang
Bone Res. 2024; 12: 31. Published online 2024 May 23. doi: 10.1038/s41413-024-00336-6
PMCID:
PMC11116389
AbstractArticlePDF–4.0M
8.
HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells
Han-Cheon Kim, Kyung-Chul Choi, Hyo-Kyoung Choi, Hee-Bum Kang, Mi-Jeong Kim, Yoo-Hyun Lee, Ok-Hee Lee, Jeongmin Lee, Young Jun Kim, Woojin Jun, Jae-Wook Jeong, Ho-Geun Yoon
Cell Mol Life Sci. 2010 Oct; 67(20): 3499–3510. Published online 2010 May 15. doi: 10.1007/s00018-010-0388-5
PMCID:
PMC11115716
AbstractArticlePDF–642K
9.
Interaction network of human early embryonic transcription factors
Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
PMCID:
PMC10933267
AbstractArticlePDF–2.9M
10.
Pulling rank with RNA: RANKL promotes the association of PGC-1β/RNA complexes with NCoR/HDAC3 to activate gene expression in osteoclasts
Haydee M. Torres, Dongwook Yeo, Jennifer J. Westendorf
Mol Cell. Author manuscript; available in PMC 2024 Feb 2.
Published in final edited form as: Mol Cell. 2023 Oct 5; 83(19): 3397–3399. doi: 10.1016/j.molcel.2023.09.012
PMCID:
PMC10835765
AbstractArticlePDF–462K
11.
Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2
Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou, Yujun Shi
BMC Cancer. 2023; 23: 906. Published online 2023 Sep 26. doi: 10.1186/s12885-023-11393-1
PMCID:
PMC10521566
AbstractArticlePDF–11M
12.
Histone deacetylase 3 regulates microglial function through histone deacetylation
Laura Meleady, Morgan Towriss, Jennifer Kim, Vince Bacarac, Vivien Dang, Megan E. Rowland, Annie Vogel Ciernia
Epigenetics. 2023; 18(1): 2241008. Published online 2023 Jul 28. doi: 10.1080/15592294.2023.2241008
PMCID:
PMC10392760
AbstractArticlePDF–8.5M
13.
ATXN3 controls DNA replication and transcription by regulating chromatin structure
Esperanza Hernández‐Carralero, Elisa Cabrera, Gara Rodríguez-Torres, Yeray Hernández-Reyes, Abhay N Singh, Cristina Santa-María, José Miguel Fernández-Justel, Roel C Janssens, Jurgen A Marteijn, Bernd O Evert, Niels Mailand, María Gómez, Kristijan Ramadan, Veronique A J Smits, Raimundo Freire
Nucleic Acids Res. 2023 Jun 23; 51(11): 5396–5413. Published online 2023 Mar 27. doi: 10.1093/nar/gkad212
PMCID:
PMC10287915
AbstractArticlePDF–2.1M
14.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
15.
A histone deacetylase 3 and mitochondrial complex I axis regulates toxic formaldehyde production
Niek Wit, Ewa Gogola, James A. West, Tristan Vornbäumen, Rachel V. Seear, Peter S. J. Bailey, Guillermo Burgos-Barragan, Meng Wang, Patrycja Krawczyk, Daphne H. E. W. Huberts, Fanni Gergely, Nicholas J. Matheson, Arthur Kaser, James A. Nathan, Ketan J. Patel
Sci Adv. 2023 May; 9(20): eadg2235. Published online 2023 May 17. doi: 10.1126/sciadv.adg2235
PMCID:
PMC10191432
AbstractArticlePDF–1.3M
16.
CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment
Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini
Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3
PMCID:
PMC9950183
AbstractArticlePDF–2.4M
17.
Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis
Kei-ichiro Arimoto, Sayuri Miyauchi, Ty D. Troutman, Yue Zhang, Mengdan Liu, Samuel A. Stoner, Amanda G. Davis, Jun-Bao Fan, Yi-Jou Huang, Ming Yan, Christopher K. Glass, Dong-Er Zhang
Nat Commun. 2023; 14: 251. Published online 2023 Jan 17. doi: 10.1038/s41467-022-35348-5
PMCID:
PMC9842760
AbstractArticlePDF–4.8M
18.
HDAC1/3-dependent moderate liquid–liquid phase separation of YY1 promotes METTL3 expression and AML cell proliferation
Meng Li, Mingying Li, Yuan Xia, Guosheng Li, Xiuhua Su, Dongmei Wang, Jingjing Ye, Fei Lu, Tao Sun, Chunyan Ji
Cell Death Dis. 2022 Nov; 13(11): 992. Published online 2022 Nov 24. doi: 10.1038/s41419-022-05435-y
PMCID:
PMC9691727
AbstractArticlePDF–5.9M
19.
RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes
Shalini Rawat, Dhruba Chatterjee, Rituraj Marwaha, Gitanjali Charak, Gaurav Kumar, Shrestha Shaw, Divya Khatter, Sheetal Sharma, Cecilia de Heus, Nalan Liv, Judith Klumperman, Amit Tuli, Mahak Sharma
J Cell Biol. 2023 Jan 2; 222(1): e202108001. Published online 2022 Oct 25. doi: 10.1083/jcb.202108001
PMCID:
PMC9597352
AbstractArticlePDF–12M
20.
Negative Feedback Loop Mechanism between EAF1/2 and DBC1 in Regulating ELL Stability and Functions
Subham Basu, Arijit Nandy, Mahesh K. Barad, Sujay Pal, Debabrata Biswas
Mol Cell Biol. 2022 Oct; 42(10): e00151-22. Published online 2022 Aug 29. doi: 10.1128/mcb.00151-22
PMCID:
PMC9590304
AbstractArticlePDF–3.2M

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