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Select item 115264771.

Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development

Timothy J. Mead, Sumit Bhutada, Simon J. Foulcer, Niccolò Peruzzi, Courtney M. Nelson, Deborah E. Seifert, Jonathan Larkin, Karin Tran-Lundmark, Jorge Filmus, Suneel S. Apte

Matrix Biol. Author manuscript; available in PMC 2024 Oct 31.

Published in final edited form as: Matrix Biol. 2024 Aug; 131: 1–16. Published online 2024 May 13. doi: 10.1016/j.matbio.2024.05.003

PMCID:: PMC11526477

Abstract Article PDF–5.2M

Select item 114692842.

DAMPs Drive Fibroinflammatory Changes in the Glaucomatous ONH

Emma K. Geiduschek, Emma K. Bricco, Colleen M. McDowell

Invest Ophthalmol Vis Sci. 2024 Oct; 65(12): 13. Published online 2024 Oct 9. doi: 10.1167/iovs.65.12.13

PMCID:: PMC11469284

Abstract Article PDF–10M

Select item 114160603.

β1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation

Lianjie Miao, Yangyang Lu, Anika Nusrat, Luqi Zhao, Micah Castillo, Yongqi Xiao, Hongyang Guo, Yu Liu, Preethi Gunaratne, Robert J Schwartz, Alan R Burns, Ashok Kumar, C Michael DiPersio, Mingfu Wu

Cardiovasc Res. 2024 Jul; 120(11): 1279–1294. Published online 2024 May 24. doi: 10.1093/cvr/cvae111

PMCID:: PMC11416060

Abstract Article PDF–2.6M

Select item 114113394.

In vitro differentiation of mouse pluripotent stem cells into corticosteroid-producing adrenocortical cells

Ioannis Oikonomakos, Melina Tedesco, Fariba Jian Motamedi, Mirko Peitzsch, Serge Nef, Stefan R. Bornstein, Andreas Schedl, Charlotte Steenblock, Yasmine Neirijnck

Stem Cell Reports. 2024 Sep 10; 19(9): 1289–1303. Published online 2024 Aug 22. doi: 10.1016/j.stemcr.2024.07.010

PMCID:: PMC11411339

Abstract Article PDF–5.7M

Select item 112611515.

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells

Liya Wang, Li He, Weijia Yi, Min Wang, Fangmin Xu, Hanlin Liu, Jiahui Nie, Yi-Hsuan Pan, Suying Dang, Wei Zhang

iScience. 2024 Jul 19; 27(7): 110273. Published online 2024 Jun 14. doi: 10.1016/j.isci.2024.110273

PMCID:: PMC11261151

Abstract Article PDF–3.4M

Select item 112611406.

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues

Sanjiv Neupane, Daniel B. Williamson, Robyn A. Roth, Carmen M. Halabi, Robert S. Haltiwanger, Bernadette C. Holdener

J Biol Chem. 2024 Jul; 300(7): 107445. Published online 2024 Jun 4. doi: 10.1016/j.jbc.2024.107445

PMCID:: PMC11261140

Abstract Article PDF–8.6M

Select item 112591597.

A fibronectin gradient remodels mixed-phase mesoderm

Min Zhu, Bin Gu, Evan C. Thomas, Yunyun Huang, Yun-Kyo Kim, Hirotaka Tao, Theodora M. Yung, Xin Chen, Kaiwen Zhang, Elizabeth K. Woolaver, Mikaela R. Nevin, Xi Huang, Rudolph Winklbauer, Janet Rossant, Yu Sun, Sevan Hopyan

Sci Adv. 2024 Jul 19; 10(29): eadl6366. Published online 2024 Jul 19. doi: 10.1126/sciadv.adl6366

PMCID:: PMC11259159

Abstract Article PDF–6.7M

Select item 112399348.

ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex

Noe Kaneko, Kumiko Hirai, Minori Oshima, Kei Yura, Mitsuharu Hattori, Nobuaki Maeda, Chiaki Ohtaka-Maruyama

EMBO Rep. 2024 Jul; 25(7): 3090–3115. Published online 2024 Jun 13. doi: 10.1038/s44319-024-00174-x

PMCID:: PMC11239934

Abstract Article PDF–8.6M

Select item 111473779.

Ultrastructural localization of microfibrillar fibulin-1 and fibulin-2 during heart development indicates a switch in molecular associations

N. Miosge, T. Sasaki, M.-L. Chu, R. Herken, R. Timpl

Cell Mol Life Sci. 1998 Jun; 54(6): 606–613. doi: 10.1007/s000180050188

PMCID:: PMC11147377

Abstract Article PDF–986K

Select item 1113972410.

The extracellular matrix protein fibronectin promotes metanephric kidney development

Kathrin Skoczynski, Andre Kraus, Christoph Daniel, Maike Büttner-Herold, Kerstin Amann, Mario Schiffer, Kristina Hermann, Leonie Herrnberger-Eimer, Ernst R. Tamm, Bjoern Buchholz

Pflugers Arch. 2024; 476(6): 963–974. Published online 2024 Apr 2. doi: 10.1007/s00424-024-02954-9

PMCID:: PMC11139724

Abstract Article PDF–11M

Select item 1112661311.

A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells

Christopher J. Benwell, Robert T. Johnson, James A. G. E. Taylor, Jordi Lambert, Stephen D. Robinson

Commun Biol. 2024; 7: 629. Published online 2024 May 24. doi: 10.1038/s42003-024-06320-4

PMCID:: PMC11126613

Abstract Article PDF–8.0M

Select item 1098766212.

Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin

Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan

EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y

PMCID:: PMC10987662

Abstract Article PDF–12M

Select item 1084282413.

SMAD4: A Critical Regulator of Cardiac Neural Crest Cell Fate and Vascular Smooth Muscle Development

Brianna E. Alexander, Huaning Zhao, Sophie Astrof

Dev Dyn. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Dev Dyn. 2024 Jan; 253(1): 119–143. Published online 2023 Aug 31. doi: 10.1002/dvdy.652

PMCID:: PMC10842824

Abstract Article PDF–5.9M

Select item 1083968914.

Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice

Salli Talvi, Johanna Jokinen, Kalle Sipilä, Pekka Rappu, Fu-Ping Zhang, Matti Poutanen, Pia Rantakari, Jyrki Heino

iScience. 2024 Feb 16; 27(2): 108914. Published online 2024 Jan 15. doi: 10.1016/j.isci.2024.108914

PMCID:: PMC10839689

Abstract Article PDF–5.9M

Select item 1068676515.

Aberrant Differentiation of Second Heart Field Mesoderm Prefigures Cellular Defects in the Outflow Tract in Response to Loss of FGF8

Sophie Astrof, Cecilia Arriagada, Yukio Saijoh, Alexandre Francou, Robert G. Kelly, Anne Moon

Dev Biol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Dev Biol. 2023 Jul; 499: 10–21. Published online 2023 Apr 14. doi: 10.1016/j.ydbio.2023.04.001

PMCID:: PMC10686765

Abstract Article PDF–2.2M

Select item 1054589116.

Unravelling the role of immune cells and FN1 in the recurrence and therapeutic process of skull base chordoma

Xulei Huo, Sihan Ma, Can Wang, Lairong Song, Bohan Yao, Sipeng Zhu, Peiran Li, Liang Wang, Zhen Wu, Ke Wang

Clin Transl Med. 2023 Oct; 13(10): e1429. Published online 2023 Oct 2. doi: 10.1002/ctm2.1429

PMCID:: PMC10545891

Abstract Article PDF–4.9M

Select item 1050641317.

Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development

Jinshu Xu, Xianxiao Zhou, Ting Zhang, Bin Zhang, Pin-Xian Xu

Front Cell Dev Biol. 2023; 11: 1233317. Published online 2023 Sep 4. doi: 10.3389/fcell.2023.1233317

PMCID:: PMC10506413

Abstract Article PDF–7.2M

Select item 1047617418.

Embryo‐uterine interaction coordinates mouse embryogenesis during implantation

Vladyslav Bondarenko, Mikhail Nikolaev, Dimitri Kromm, Roman Belousov, Adrian Wolny, Marloes Blotenburg, Peter Zeller, Saba Rezakhani, Johannes Hugger, Virginie Uhlmann, Lars Hufnagel, Anna Kreshuk, Jan Ellenberg, Alexander van Oudenaarden, Anna Erzberger, Matthias P Lutolf, Takashi Hiiragi

EMBO J. 2023 Sep; 42(17): e113280. Published online 2023 Jul 31. doi: 10.15252/embj.2022113280

PMCID:: PMC10476174

Abstract Article PDF–4.7M

Select item 1042106719.

Emergent mechanical control of vascular morphogenesis

Jordan Whisler, Somayeh Shahreza, Karin Schlegelmilch, Nil Ege, Yousef Javanmardi, Andrea Malandrino, Ayushi Agrawal, Alessandro Fantin, Bianca Serwinski, Hesham Azizgolshani, Clara Park, Victoria Shone, Olukunle O. Demuren, Amanda Del Rosario, Vincent L. Butty, Natalie Holroyd, Marie-Charlotte Domart, Steven Hooper, Nicolas Szita, Laurie A. Boyer, Simon Walker-Samuel, Boris Djordjevic, Graham K. Sheridan, Lucy Collinson, Fernando Calvo, Christiana Ruhrberg, Erik Sahai, Roger Kamm, Emad Moeendarbary

Sci Adv. 2023 Aug; 9(32): eadg9781. Published online 2023 Aug 11. doi: 10.1126/sciadv.adg9781

PMCID:: PMC10421067

Abstract Article PDF–1.8M

Select item 1041013720.

Matrix stiffness controls megakaryocyte adhesion, fibronectin fibrillogenesis, and proplatelet formation through Itgβ3

Ines Guinard, Thao Nguyen, Noémie Brassard-Jollive, Josiane Weber, Laurie Ruch, Laura Reininger, Nathalie Brouard, Anita Eckly, Dominique Collin, François Lanza, Catherine Léon

Blood Adv. 2023 Aug 8; 7(15): 4003–4018. Published online 2023 May 15. doi: 10.1182/bloodadvances.2022008680

PMCID:: PMC10410137

Abstract Article PDF–7.2M

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