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Select item 109332011.

Crosstalk between purinergic receptor P2Y₁₁ and chemokine receptor CXCR7 is regulated by CXCR4 in human macrophages

Dominik Klaver, Hubert Gander, Beatrice Frena, Marco Amato, Martin Thurnher

Cell Mol Life Sci. 2024 Dec; 81(1): 132. Published online 2024 Mar 13. doi: 10.1007/s00018-024-05158-7

PMCID:: PMC10933201

Abstract Article PDF–4.5M

Select item 106904702.

Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages

Line Lykke Andersen, Yiqi Huang, Christian Urban, Lila Oubraham, Elena Winheim, Che Stafford, Dennis Nagl, Fionan O'Duill, Thomas Ebert, Thomas Engleitner, Søren Riis Paludan, Anne Krug, Roland Rad, Veit Hornung, Andreas Pichlmair

EMBO J. 2023 Dec; 42(23): e113279. Published online 2023 Oct 26. doi: 10.15252/embj.2022113279

PMCID:: PMC10690470

Abstract Article PDF–2.0M

Select item 102374223.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 100736264.

P2Y₁₁/IL-1 receptor crosstalk controls macrophage inflammation: a novel target for anti-inflammatory strategies?

Dominik Klaver, Martin Thurnher

Purinergic Signal. 2023 Sep; 19(3): 501–511. Published online 2023 Apr 5. doi: 10.1007/s11302-023-09932-3

PMCID:: PMC10073626

Abstract Article PDF–929K

Select item 99729455.

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang

J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22

PMCID:: PMC9972945

Abstract Article PDF–3.0M

Select item 97725586.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 95403457.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 94764238.

The P2Y₁₁ receptor of human M2 macrophages activates canonical and IL-1 receptor signaling to translate the extracellular danger signal ATP into anti-inflammatory and pro-angiogenic responses

Dominik Klaver, Hubert Gander, Gabriele Dobler, Andrea Rahm, Martin Thurnher

Cell Mol Life Sci. 2022; 79(10): 519. Published online 2022 Sep 15. doi: 10.1007/s00018-022-04548-z

PMCID:: PMC9476423

Abstract Article PDF–2.3M

Select item 94375639.

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk

Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird

Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205

PMCID:: PMC9437563

Abstract Article PDF–9.5M

Select item 882677310.

The purinergic receptor P2Y11 choreographs the polarization, mitochondrial metabolism, and migration of T lymphocytes

Carola Ledderose, Sophie Bromberger, Christian J. Slubowski, Koichiro Sueyoshi, Dilan Aytan, Yong Shen, Wolfgang G. Junger

Sci Signal. Author manuscript; available in PMC 2022 Feb 9.

Published in final edited form as: Sci Signal. 2020 Sep 29; 13(651): eaba3300. Published online 2020 Sep 29. doi: 10.1126/scisignal.aba3300

PMCID:: PMC8826773

Abstract Article PDF–1.3M

Select item 877228711.

P2Y11 receptors support T cell activation by directing mitochondrial trafficking to the immune synapse

Carola Ledderose, Sophie Bromberger, Christian J. Slubowski, Koichiro Sueyoshi, Wolfgang G. Junger

J Leukoc Biol. Author manuscript; available in PMC 2022 Jan 20.

Published in final edited form as: J Leukoc Biol. 2021 Mar; 109(3): 497–508. Published online 2020 Jun 12. doi: 10.1002/JLB.2HI0520-191R

PMCID:: PMC8772287

Abstract Article PDF–2.1M

Select item 836134512.

High nocturnal sleep fragmentation is associated with low T lymphocyte P2Y₁₁ protein levels in narcolepsy type 1

Rannveig Viste, Marte K Viken, Benedicte A Lie, Hilde T Juvodden, Sebjørg E H Nordstrand, Per M Thorsby, Terje Rootwelt, Birgitte R Kornum, Stine Knudsen-Heier

Sleep. 2021 Aug; 44(8): zsab062. Published online 2021 Mar 12. doi: 10.1093/sleep/zsab062

PMCID:: PMC8361345

Abstract Article PDF–4.2M

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 677813714.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 669555715.

The Human G Protein-Coupled ATP Receptor P2Y₁₁ Is Associated With IL-10 Driven Macrophage Differentiation

Georg Gruenbacher, Hubert Gander, Andrea Rahm, Gabriele Dobler, Astrid Drasche, Jakob Troppmair, Walter Nussbaumer, Martin Thurnher

Front Immunol. 2019; 10: 1870. Published online 2019 Aug 9. doi: 10.3389/fimmu.2019.01870

PMCID:: PMC6695557

Abstract Article PDF–3.0M

Select item 648412016.

Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors

Koichiro Sueyoshi, Carola Ledderose, Yong Shen, Albert H. Lee, Nathan I. Shapiro, Wolfgang G. Junger

J Biol Chem. 2019 Apr 19; 294(16): 6283–6293. Published online 2019 Feb 20. doi: 10.1074/jbc.RA118.007188

PMCID:: PMC6484120

Abstract Article PDF–2.0M

Select item 646186417.

LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition

Qingsong Hu, Chunlai Li, Shouyu Wang, Yajuan Li, Bo Wen, Yanyan Zhang, Ke Liang, Jun Yao, Youqiong Ye, Heidi Hsiao, Tina K. Nguyen, Peter K. Park, Sergey D. Egranov, David H. Hawke, Jeffrey R. Marks, Leng Han, Mien-Chie Hung, Bing Zhang, Chunru Lin, Liuqing Yang

Cell Res. 2019 Apr; 29(4): 286–304. Published online 2019 Jan 10. doi: 10.1038/s41422-018-0134-3

PMCID:: PMC6461864

Abstract Article PDF–11M

Select item 642409818.

PRISMA: Protein Interaction Screen on Peptide Matrix Reveals Interaction Footprints and Modifications- Dependent Interactome of Intrinsically Disordered C/EBPβ

Gunnar Dittmar, Daniel Perez Hernandez, Elisabeth Kowenz-Leutz, Marieluise Kirchner, Günther Kahlert, Radoslaw Wesolowski, Katharina Baum, Maria Knoblich, Maria Hofstätter, Arnaud Muller, Jana Wolf, Ulf Reimer, Achim Leutz

iScience. 2019 Mar 29; 13: 351–370. Published online 2019 Mar 1. doi: 10.1016/j.isci.2019.02.026

PMCID:: PMC6424098

Abstract Article PDF–11M

Select item 622622519.

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation

Jaewoo Choi, Anita Saraf, Laurence Florens, Michael P. Washburn, Luca Busino

Cell Cycle. 2018; 17(18): 2243–2255. Published online 2018 Sep 25. doi: 10.1080/15384101.2018.1522912

PMCID:: PMC6226225

Abstract Article PDF–1.7M

Select item 600248420.

Human P2Y₁₁ Expression Level Affects Human P2X7 Receptor-Mediated Cell Death

Karin Dreisig, Louise Sund, Maja Wallentin Dommer, Nikolaj Pagh Kristensen, Kim Boddum, Rannveig Viste, Simon Fredholm, Niels Odum, Marja Jäättelä, Søren Skov, Birgitte R. Kornum

Front Immunol. 2018; 9: 1159. Published online 2018 Jun 8. doi: 10.3389/fimmu.2018.01159

PMCID:: PMC6002484

Abstract Article PDF–2.1M

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