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Select item 111361281.

Retinoblastoma family proteins: insights gained through genetic manipulation of mice

K. A. Wikenheiser-Brokamp

Cell Mol Life Sci. 2006 Apr; 63(7-8): 767–780. Published online 2006 Feb 7. doi: 10.1007/s00018-005-5487-3

PMCID:: PMC11136128

Abstract Article PDF–227K

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106003413.

STRA8–RB interaction is required for timely entry of meiosis in mouse female germ cells

Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro

Nat Commun. 2023; 14: 6443. Published online 2023 Oct 25. doi: 10.1038/s41467-023-42259-6

PMCID:: PMC10600341

Abstract Article PDF–12M

Select item 93673314.

Pten and p53 Loss in the Mouse Lung Causes Adenocarcinoma and Sarcomatoid Carcinoma

Sara Lázaro, Corina Lorz, Ana Belén Enguita, Iván Seller, Jesús M. Paramio, Mirentxu Santos

Cancers (Basel) 2022 Aug; 14(15): 3671. Published online 2022 Jul 28. doi: 10.3390/cancers14153671

PMCID:: PMC9367331

Abstract Article PDF–2.7M

Select item 89819705.

Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity

Joel D. Pearson, Katherine Huang, Marek Pacal, Sean R. McCurdy, Suying Lu, Arthur Aubry, Tao Yu, Kristine M. Wadosky, Letian Zhang, Tao Wang, Alex Gregorieff, Mohammad Ahmad, Helen Dimaras, Ellen Langille, Susan P.C. Cole, Philippe P. Monnier, Benjamin H. Lok, Ming-Sound Tsao, Nagako Akeno, Daniel Schramek, Kathryn A. Wikenheiser-Brokamp, Erik S. Knudsen, Agnieszka K. Witkiewicz, Jeffrey L. Wrana, David W. Goodrich, Rod Bremner

Cancer Cell. Author manuscript; available in PMC 2022 Apr 5.

Published in final edited form as: Cancer Cell. 2021 Aug 9; 39(8): 1115–1134.e12. Published online 2021 Jul 21. doi: 10.1016/j.ccell.2021.06.016

PMCID:: PMC8981970

Abstract Article PDF–4.3M

Select item 85641176.

Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons

Remi Akagawa, Yo-ichi Nabeshima, Takeshi Kawauchi

Front Cell Dev Biol. 2021; 9: 753175. Published online 2021 Oct 20. doi: 10.3389/fcell.2021.753175

PMCID:: PMC8564117

Abstract Article PDF–2.2M

Select item 85144687.

p107 mediated mitochondrial function controls muscle stem cell proliferative fates

Debasmita Bhattacharya, Vicky Shah, Oreoluwa Oresajo, Anthony Scimè

Nat Commun. 2021; 12: 5977. Published online 2021 Oct 13. doi: 10.1038/s41467-021-26176-0

PMCID:: PMC8514468

Abstract Article PDF–2.4M

Select item 83745248.

InVision: An optimized tissue clearing approach for three-dimensional imaging and analysis of intact rodent eyes

Akshay Gurdita, Philip E.B. Nickerson, Neno T. Pokrajac, Arturo Ortín-Martínez, En Leh Samuel Tsai, Lacrimioara Comanita, Nicole E. Yan, Parnian Dolati, Nobuhiko Tachibana, Zhongda C. Liu, Joel D. Pearson, Danian Chen, Rod Bremner, Valerie A. Wallace

iScience. 2021 Aug 20; 24(8): 102905. Published online 2021 Jul 26. doi: 10.1016/j.isci.2021.102905

PMCID:: PMC8374524

Abstract Article PDF–7.7M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 788040910.

Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice

Pirunthan Perampalam, Haider M. Hassan, Grace E. Lilly, Daniel T. Passos, Joseph Torchia, Patti K. Kiser, Andrea Bozovic, Vathany Kulasingam, Frederick A. Dick

J Clin Invest. 2021 Feb 15; 131(4): e140903. Published online 2021 Feb 15. doi: 10.1172/JCI140903

PMCID:: PMC7880409

Abstract Article PDF–8.5M

Select item 702899611.

Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression

Loredana Zocchi, Aditi Mehta, Stephanie C. Wu, Jie Wu, Yijun Gu, Jingtian Wang, Susie Suh, Robert C. Spitale, Claudia A. Benavente

Oncogenesis. 2020 Feb; 9(2): 25. Published online 2020 Feb 18. doi: 10.1038/s41389-020-0210-7

PMCID:: PMC7028996

Abstract Article PDF–1.3M

Select item 694886612.

Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma

Ran Wei, Xiang Ren, Hongyu Kong, Zhongping Lv, Yongjiang Chen, Yunjing Tang, Yujiao Wang, Lirong Xiao, Tao Yu, Sabiha Hacibekiroglu, Chen Liang, Andras Nagy, Rod Bremner, Danian Chen

JCI Insight. 2019 Nov 14; 4(22): e127889. Published online 2019 Nov 14. doi: 10.1172/jci.insight.127889

PMCID:: PMC6948866

Abstract Article PDF–19M

Select item 682527513.

Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes

Sara Lázaro, Miriam Pérez-Crespo, Corina Lorz, Alejandra Bernardini, Marta Oteo, Ana Belén Enguita, Eduardo Romero, Pilar Hernández, Laura Tomás, Miguel Ángel Morcillo, Jesús M. Paramio, Mirentxu Santos

Proc Natl Acad Sci U S A. 2019 Oct 29; 116(44): 22300–22306. Published online 2019 Oct 14. doi: 10.1073/pnas.1821745116

PMCID:: PMC6825275

Abstract Article PDF–1.9M

Select item 671942914.

Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs

Jérôme Mastio, Thomas Condamine, George Dominguez, Andrew V. Kossenkov, Laxminarasimha Donthireddy, Filippo Veglia, Cindy Lin, Fang Wang, Shuyu Fu, Jie Zhou, Patrick Viatour, Sergio Lavilla-Alonso, Alexander T. Polo, Evgenii N. Tcyganov, Charles Mulligan, Jr., Brian Nam, Joseph Bennett, Gregory Masters, Michael Guarino, Amit Kumar, Yulia Nefedova, Robert H. Vonderheide, Lucia R. Languino, Scott I. Abrams, Dmitry I. Gabrilovich

J Exp Med. 2019 Sep 2; 216(9): 2150–2169. Published online 2019 Jun 25. doi: 10.1084/jem.20181952

PMCID:: PMC6719429

Abstract Article PDF–4.1M

Select item 550242015.

Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression

Eunsun Kim, Ying Cheng, Elisabeth Bolton-Gillespie, Xiongwei Cai, Connie Ma, Amy Tarangelo, Linh Le, Madhumita Jambhekar, Pichai Raman, Katharina E. Hayer, Gerald Wertheim, Nancy A. Speck, Wei Tong, Patrick Viatour

J Exp Med. 2017 Jul 3; 214(7): 1901–1912. doi: 10.1084/jem.20160719

PMCID:: PMC5502420

Abstract Article PDF–1.9M

Select item 542371816.

In vivo interplay between p27^Kip1, GATA3, ATOH1, and POU4F3 converts non-sensory cells to hair cells in adult mice

Bradley J. Walters, Emily Coak, Jennifer Dearman, Grace Bailey, Tetsuji Yamashita, Bryan Kuo, Jian Zuo

Cell Rep. Author manuscript; available in PMC 2017 May 9.

Published in final edited form as: Cell Rep. 2017 Apr 11; 19(2): 307–320. doi: 10.1016/j.celrep.2017.03.044

PMCID:: PMC5423718

Abstract Article PDF–3.0M

Select item 535483917.

Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation

Sara Lázaro, Miriam Pérez-Crespo, Ana Belén Enguita, Pilar Hernández, Jesús Martínez-Palacio, Marta Oteo, Julien Sage, Jesús M. Paramio, Mirentxu Santos

Oncotarget. 2017 Jan 17; 8(3): 4373–4386. Published online 2016 Dec 10. doi: 10.18632/oncotarget.13875