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Items: 1 to 20 of 88

1.
Hippo kinases Mst1 and Mst2 maintain NK cell homeostasis by orchestrating metabolic state and transcriptional activity
Peiran Feng, Liang Luo, Quanli Yang, Wanqing Meng, Zerong Guan, Zhizhong Li, Guodong Sun, Zhongjun Dong, Meixiang Yang
Cell Death Dis. 2024 Jun; 15(6): 430. Published online 2024 Jun 19. doi: 10.1038/s41419-024-06828-x
PMCID:
PMC11187177
AbstractArticlePDF–6.0M
2.
MST1/2 regulates fibro/adipogenic progenitor fate decisions in skeletal muscle regeneration
Kezhi Wang, Jingjing Yang, Yina An, Jing Wang, Shuyu Tan, Hui Xu, Yanjun Dong
Stem Cell Reports. 2024 Apr 9; 19(4): 501–514. Published online 2024 Mar 28. doi: 10.1016/j.stemcr.2024.02.010
PMCID:
PMC11096422
AbstractArticlePDF–6.9M
3.
The Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
Dae Jin Jeong, Jee-Hyun Um, Young Yeon Kim, Dong Jin Shin, Sangwoo Im, Kang-Min Lee, Yun-Hee Lee, Dae-sik Lim, Donghoon Kim, Jeanho Yun
Exp Mol Med. 2024 Mar; 56(3): 674–685. Published online 2024 Mar 5. doi: 10.1038/s12276-024-01198-y
PMCID:
PMC10984967
AbstractArticlePDF–4.8M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Epinephrine inhibits PI3Kα via the Hippo kinases
Ting-Yu Lin, Shakti Ramsamooj, Tiffany Perrier, Katarina Liberatore, Louise Lantier, Neil Vasan, Kannan Karukurichi, Seo-Kyoung Hwang, Edward A. Kesicki, Edward R. Kastenhuber, Thorsten Wiederhold, Tomer M. Yaron, Emily M. Huntsman, Mengmeng Zhu, Yilun Ma, Marcia N. Paddock, Guoan Zhang, Benjamin D. Hopkins, Owen McGuinness, Robert E. Schwartz, Baran A. Ersoy, Lewis C. Cantley, Jared L. Johnson, Marcus D. Goncalves
Cell Rep. Author manuscript; available in PMC 2024 Jan 25.
Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113535. Published online 2023 Dec 4. doi: 10.1016/j.celrep.2023.113535
PMCID:
PMC10809223
AbstractArticlePDF–2.3M
6.
Inactivation of MST1/2 Controls Macrophage Polarization to Affect Macrophage-Related Disease via YAP and Non-YAP Mechanisms
Yina An, Shuyu Tan, Pu Zhang, Jingjing Yang, Kezhi Wang, Ruicheng Zheng, Lu Qiao, Yang Wang, Yanjun Dong
Int J Biol Sci. 2024; 20(3): 1004–1023. Published online 2024 Jan 12. doi: 10.7150/ijbs.87057
PMCID:
PMC10797691
AbstractArticlePDF–25M
7.
Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis
Samira Benhamouche-Trouillet, Evan O'Loughlin, Ching-Hui Liu, William Polacheck, Julien Fitamant, Mary McKee, Nabeel El-Bardeesy, Christopher S. Chen, Andrea I. McClatchey
Development. 2018 May 1; 145(9): dev162123. Published online 2018 Apr 30. doi: 10.1242/dev.162123
PMCID:
PMC10682933
AbstractArticle
8.
Regenerative reprogramming of the intestinal stem cell state via Hippo signaling suppresses metastatic colorectal cancer
Priscilla Cheung, Jordi Xiol, Michael T. Dill, Wei-Chien Yuan, Riccardo Panero, Jatin Roper, Fernando G. Osorio, Dejan Maglic, Qi Li, Basanta Gurung, Raffaele A. Calogero, Ömer H. Yilmaz, Junhao Mao, Fernando D. Camargo
Cell Stem Cell. Author manuscript; available in PMC 2023 Apr 19.
Published in final edited form as: Cell Stem Cell. 2020 Oct 1; 27(4): 590–604.e9. Published online 2020 Jul 29. doi: 10.1016/j.stem.2020.07.003
PMCID:
PMC10114498
AbstractArticlePDF–2.4M
9.
Serine/threonine kinase 3 promotes oxidative stress and mitochondrial damage in septic cardiomyopathy through inducing Kelch-like ECH-associated protein 1 phosphorylation and nuclear factor erythroid 2-related factor 2 degradation
Hang Zhu, Zhe Dai, Xiaoman Liu, Hao Zhou, Yijin Wang
Int J Biol Sci. 2023; 19(5): 1369–1381. Published online 2023 Feb 21. doi: 10.7150/ijbs.80800
PMCID:
PMC10086747
AbstractArticlePDF–6.4M
10.
A Stk4 -Foxp3-P65 Transcriptional Complex Promotes Treg Cell Activation and Homeostasis
Ye Cui, Mehdi Benamar, Klaus Schmitz-Abe, Varsha Poondi-Krishnan, Qian Chen, Bat-Erdene Jugder, Benoit Fatou, Jason Fong, Yuelin Zhong, Stuti Mehta, Altantsetseg Buyanbat, Beray Selver Eklioglu, Esra Karabiber, Safa Baris, Ayca Kiykim, Sevgi Keles, Emmanuel Stephen-Victor, Claudia Angelini, Louis-Marie Charbonnier, Talal A. Chatila
Sci Immunol. Author manuscript; available in PMC 2023 Jan 6.
Published in final edited form as: Sci Immunol. 2022 Sep 23; 7(75): eabl8357. Published online 2022 Sep 23. doi: 10.1126/sciimmunol.abl8357
PMCID:
PMC9816918
AbstractArticlePDF–3.0M
11.
Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers
Fakhreddin Yaghoob Nezhad, Annett Riermeier, Martin Schönfelder, Lore Becker, Martin Hrabĕ de Angelis, Henning Wackerhage
Transgenic Res. 2022; 31(2): 227–237. Published online 2022 Jan 5. doi: 10.1007/s11248-021-00293-4
PMCID:
PMC8993742
AbstractArticlePDF–3.8M
12.
STK25 and MST3 Have Overlapping Roles to Regulate Rho GTPases during Cortical Development
Tohru Matsuki, Akio Iio, Masashi Ueda, Yumi Tsuneura, Brian W. Howell, Atsuo Nakayama
J Neurosci. 2021 Oct 27; 41(43): 8887–8903. doi: 10.1523/JNEUROSCI.0523-21.2021
PMCID:
PMC8549536
AbstractArticlePDF–6.2M
13.
YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1
Jason J. Gokey, John Snowball, Anusha Sridharan, Parvathi Sudha, Joseph A. Kitzmiller, Yan Xu, Jeffrey A. Whitsett
iScience. 2021 Sep 24; 24(9): 102967. Published online 2021 Aug 11. doi: 10.1016/j.isci.2021.102967
PMCID:
PMC8383002
AbstractArticlePDF–4.4M
14.
Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions
Jana L. Raynor, Chaohong Liu, Yogesh Dhungana, Cliff Guy, Nicole M. Chapman, Hao Shi, Geoffrey Neale, Hiromi Sesaki, Hongbo Chi
J Exp Med. 2020 Jun 1; 217(6): e20191157. Published online 2020 Apr 14. doi: 10.1084/jem.20191157
PMCID:
PMC7971129
AbstractArticlePDF–7.3M
15.
Treatment with Mammalian Ste-20-like Kinase 1/2 (MST1/2) Inhibitor XMU-MP-1 Improves Glucose Tolerance in Streptozotocin-Induced Diabetes Mice
Zakiyatul Faizah, Bella Amanda, Faisal Yusuf Ashari, Efta Triastuti, Rebecca Oxtoby, Anny Setijo Rahaju, M. Aminudin Aziz, Maria Inge Lusida, Delvac Oceandy
Molecules. 2020 Oct; 25(19): 4381. Published online 2020 Sep 24. doi: 10.3390/molecules25194381
PMCID:
PMC7582334
AbstractArticlePDF–2.5M
16.
Netrin1 deficiency activates MST1 via UNC5B receptor, promoting dopaminergic apoptosis in Parkinson’s disease
Eun Hee Ahn, Seong Su Kang, Qi Qi, Xia Liu, Keqiang Ye
Proc Natl Acad Sci U S A. 2020 Sep 29; 117(39): 24503–24513. Published online 2020 Sep 14. doi: 10.1073/pnas.2004087117
PMCID:
PMC7533679
AbstractArticlePDF–2.1M
17.
Hippo kinases MST1 and MST2 control the differentiation of the epididymal initial segment via the MEK-ERK pathway
Chenling Meng, Geng Tian, Chunhua Xu, Xiaofeng Li, Yu Zhang, Yang Wang, Jinzhong Qin, Ellis Kin Lam Fok, Barry T. Hinton, Kingston King-lun Mak, Winnie Waichi Shum, Wai-Yee Chan, Yin Xia
Cell Death Differ. 2020 Oct; 27(10): 2797–2809. Published online 2020 Apr 24. doi: 10.1038/s41418-020-0544-x
PMCID:
PMC7492226
AbstractArticlePDF–5.0M
18.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
19.
Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers
Xiang Sun, Zhijun Ren, Yixian Cun, Cai Zhao, Xianglin Huang, Jiajian Zhou, Rong Hu, Xiaoxi Su, Lu Ji, Peng Li, King Lun Kingston Mak, Feng Gao, Yi Yang, He Xu, Junjun Ding, Nan Cao, Shuo Li, Wensheng Zhang, Ping Lan, Hao Sun, Jinkai Wang, Ping Yuan
Nucleic Acids Res. 2020 Jul 27; 48(13): 7182–7196. Published online 2020 Jun 8. doi: 10.1093/nar/gkaa482
PMCID:
PMC7367178
AbstractArticlePDF–9.6M
20.
Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms
Chunhua Xu, Li Wang, Yu Zhang, Wenling Li, Jinhong Li, Yang Wang, Chenling Meng, Jinzhong Qin, Zhi-Hua Zheng, Hui-Yao Lan, Kingston King-Lun Mak, Yu Huang, Yin Xia
J Am Soc Nephrol. 2020 May; 31(5): 946–961. Published online 2020 Apr 6. doi: 10.1681/ASN.2019101052
PMCID:
PMC7217407
AbstractArticle

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