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Items: 1 to 20 of 63

1.
Bloom syndrome patients and mice display accelerated epigenetic aging
Jamie Lee, Joshua Zhang, Maeve Flanagan, Julian A. Martinez, Christopher Cunniff, Nicole Kucine, Ake T. Lu, Amin Haghani, Juozas Gordevičius, Steve Horvath, Vivian Y. Chang
Aging Cell. 2023 Oct; 22(10): e13964. Published online 2023 Aug 18. doi: 10.1111/acel.13964
PMCID:
PMC10577546
AbstractArticlePDF–9.2M
2.
Fance deficiency inhibits primordial germ cell proliferation associated with transcription–replication conflicts accumulate and DNA repair defects
Zhixian Zhou, Huan Yin, Suye Suye, Zhen Ren, Lei Yan, Liye Shi, Chun Fu
J Ovarian Res. 2023; 16: 160. Published online 2023 Aug 10. doi: 10.1186/s13048-023-01252-9
PMCID:
PMC10416540
AbstractArticlePDF–15M
3.
SPIDR is required for homologous recombination during mammalian meiosis
Tao Huang, Xinyue Wu, Shiyu Wang, Ziyou Bao, Yanling Wan, Ziqi Wang, Mengjing Li, Xiaochen Yu, Yue Lv, Zhaojian Liu, Xiangfeng Chen, Wai-Yee Chan, Fei Gao, Gang Lu, Zi-Jiang Chen, Hongbin Liu
Nucleic Acids Res. 2023 May 8; 51(8): 3855–3868. Published online 2023 Mar 20. doi: 10.1093/nar/gkad154
PMCID:
PMC10164582
AbstractArticlePDF–11M
4.
Involvement of a BH3-only apoptosis sensitizer gene Blm-s in hippocampus-mediated mood control
Pei-Hsin Huang, Tsung-Ying Yang, Chia-Wei Yeh, Sheng-Min Huang, Ho-Ching Chang, Yun-Fen Hung, Wen-Chia Chu, Kuan-Hung Cho, Tzu-Pin Lu, Po-Hsiu Kuo, Li-Jen Lee, Li-Wei Kuo, Cheng-Chang Lien, Hwai-Jong Cheng
Transl Psychiatry. 2022; 12: 411. Published online 2022 Sep 26. doi: 10.1038/s41398-022-02184-6
PMCID:
PMC9512807
AbstractArticlePDF–5.7M
5.
Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer
Nathan F. Schachter, Jessica R. Adams, Patryk Skowron, Katelyn. J. Kozma, Christian A. Lee, Nandini Raghuram, Joanna Yang, Amanda J. Loch, Wei Wang, Aaron Kucharczuk, Katherine L. Wright, Rita M. Quintana, Yeji An, Daniel Dotzko, Jennifer L. Gorman, Daria Wojtal, Juhi S. Shah, Paul Leon-Gomez, Giovanna Pellecchia, Adam J. Dupuy, Charles M. Perou, Ittai Ben-Porath, Rotem Karni, Eldad Zacksenhaus, Jim R. Woodgett, Susan J. Done, Livia Garzia, A. Sorana Morrissy, Jüri Reimand, Michael D. Taylor, Sean E. Egan
Nat Commun. 2021; 12: 5238. Published online 2021 Sep 2. doi: 10.1038/s41467-021-25467-w
PMCID:
PMC8413298
AbstractArticlePDF–4.4M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Heterozygous germline BLM mutations increase susceptibility to asbestos and mesothelioma
Angela Bononi, Keisuke Goto, Guntulu Ak, Yoshie Yoshikawa, Mitsuru Emi, Sandra Pastorino, Lorenzo Carparelli, Angelica Ferro, Masaki Nasu, Jin-Hee Kim, Joelle S. Suarez, Ronghui Xu, Mika Tanji, Yasutaka Takinishi, Michael Minaai, Flavia Novelli, Ian Pagano, Giovanni Gaudino, Harvey I. Pass, Joanna Groden, Joseph J. Grzymski, Muzaffer Metintas, Muhittin Akarsu, Betsy Morrow, Raffit Hassan, Haining Yang, Michele Carbone
Proc Natl Acad Sci U S A. 2020 Dec 29; 117(52): 33466–33473. Published online 2020 Dec 14. doi: 10.1073/pnas.2019652117
PMCID:
PMC7776606
AbstractArticlePDF–1.3M
8.
BLM has Contrary Effects on Repeat-Mediated Deletions, based on the Distance of DNA DSBs to a Repeat and Repeat Divergence
Carlos Mendez-Dorantes, L. Jillianne Tsai, Eva Jahanshir, Felicia Wednesday Lopezcolorado, Jeremy M. Stark
Cell Rep. Author manuscript; available in PMC 2020 Mar 21.
Published in final edited form as: Cell Rep. 2020 Feb 4; 30(5): 1342–1357.e4. doi: 10.1016/j.celrep.2020.01.001
PMCID:
PMC7085117
AbstractArticlePDF–2.5M
9.
PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice
Julia Weber, Jorge de la Rosa, Carolyn S. Grove, Markus Schick, Lena Rad, Olga Baranov, Alexander Strong, Anja Pfaus, Mathias J. Friedrich, Thomas Engleitner, Robert Lersch, Rupert Öllinger, Michael Grau, Irene Gonzalez Menendez, Manuela Martella, Ursula Kohlhofer, Ruby Banerjee, Maria A. Turchaninova, Anna Scherger, Gary J. Hoffman, Julia Hess, Laura B. Kuhn, Tim Ammon, Johnny Kim, Günter Schneider, Kristian Unger, Ursula Zimber-Strobl, Mathias Heikenwälder, Marc Schmidt-Supprian, Fengtang Yang, Dieter Saur, Pentao Liu, Katja Steiger, Dmitriy M. Chudakov, Georg Lenz, Leticia Quintanilla-Martinez, Ulrich Keller, George S. Vassiliou, Juan Cadiñanos, Allan Bradley, Roland Rad
Nat Commun. 2019; 10: 1415. Published online 2019 Mar 29. doi: 10.1038/s41467-019-09180-3
PMCID:
PMC6440946
AbstractArticlePDF–2.4M
10.
Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function
Laurent Dupays, Norma Towers, Sophie Wood, Anna David, Daniel J. Stuckey, Timothy Mohun
PLoS One. 2019; 14(3): e0212992. Published online 2019 Mar 6. doi: 10.1371/journal.pone.0212992
PMCID:
PMC6402701
AbstractArticlePDF–4.3M
11.
DNA repair and cell cycle checkpoint defects in a mouse model of ‘BRCAness’ are partially rescued by 53BP1 deletion
Sarah M. Misenko, Dharm S. Patel, Joonyoung Her, Samuel F. Bunting
Cell Cycle. 2018; 17(7): 881–891. Published online 2018 May 15. doi: 10.1080/15384101.2018.1456295
PMCID:
PMC6056228
AbstractArticlePDF–1.7M
12.
BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes
Niek van Wietmarschen, Sarra Merzouk, Nancy Halsema, Diana C. J. Spierings, Victor Guryev, Peter M. Lansdorp
Nat Commun. 2018; 9: 271. Published online 2018 Jan 18. doi: 10.1038/s41467-017-02760-1
PMCID:
PMC5773480
AbstractArticlePDF–1.3M
13.
Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex
Bo Zhao, Weidao Zhang, Yixian Cun, Jingzheng Li, Yan Liu, Jing Gao, Hongwen Zhu, Hu Zhou, Rugang Zhang, Ping Zheng
Cell Res. 2018 Jan; 28(1): 69–89. Published online 2017 Nov 10. doi: 10.1038/cr.2017.139
PMCID:
PMC5752841
AbstractArticlePDF–9.1M
14.
BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites
Dharm S. Patel, Sarah M. Misenko, Joonyoung Her, Samuel F. Bunting
J Cell Biol. 2017 Nov 6; 216(11): 3521–3534. doi: 10.1083/jcb.201703144
PMCID:
PMC5674892
AbstractArticlePDF–2.2M
15.
A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes
Jorge de la Rosa, Julia Weber, Mathias Josef Friedrich, Yilong Li, Lena Rad, Hannes Ponstingl, Qi Liang, Sandra Bernaldo de Quirós, Imran Noorani, Emmanouil Metzakopian, Alexander Strong, Meng Amy Li, Aurora Astudillo, María Teresa Fernández-García, María Soledad Fernández-García, Gary J. Hoffman, Rocío Fuente, George S. Vassiliou, Roland Rad, Carlos López-Otín, Allan Bradley, Juan Cadiñanos
Nat Genet. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Genet. 2017 May; 49(5): 730–741. Published online 2017 Mar 20. doi: 10.1038/ng.3817
PMCID:
PMC5409503
AbstractArticlePDF–2.7M
16.
The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis
Juliane Braun, Arabella Meixner, Andreas Brachner, Roland Foisner
PLoS One. 2016; 11(3): e0152278. Published online 2016 Mar 24. doi: 10.1371/journal.pone.0152278
PMCID:
PMC4807109
AbstractArticlePDF–1.5M
17.
NSMCE2 suppresses cancer and aging in mice independently of its SUMO ligase activity
Ariana Jacome, Paula Gutierrez‐Martinez, Federica Schiavoni, Enrico Tenaglia, Paula Martinez, Sara Rodríguez‐Acebes, Emilio Lecona, Matilde Murga, Juan Méndez, Maria A Blasco, Oscar Fernandez‐Capetillo
EMBO J. 2015 Nov 3; 34(21): 2604–2619. Published online 2015 Oct 6. doi: 10.15252/embj.201591829
PMCID:
PMC4641528
AbstractArticlePDF–3.5M
18.
BLM helicase facilitates telomere replication during leading strand synthesis of telomeres
William C. Drosopoulos, Settapong T. Kosiyatrakul, Carl L. Schildkraut
J Cell Biol. 2015 Jul 20; 210(2): 191–208. doi: 10.1083/jcb.201410061
PMCID:
PMC4508891
AbstractArticlePDF–3.9M
19.
DNA damage-induced type I interferon promotes senescence and inhibits stem cell function
Qiujing Yu, Yuliya V. Katlinskaya, Christopher J. Carbone, Bin Zhao, Kanstantsin V. Katlinski, Hui Zheng, Manti Guha, Ning Li, Qijun Chen, Ting Yang, Christopher J. Lengner, Roger A. Greenberg, F. Brad Johnson, Serge Y. Fuchs
Cell Rep. Author manuscript; available in PMC 2016 May 5.
Published in final edited form as: Cell Rep. 2015 May 5; 11(5): 785–797. Published online 2015 Apr 23. doi: 10.1016/j.celrep.2015.03.069
PMCID:
PMC4426031
AbstractArticlePDF–1.6M
20.
Desialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin binding
Mihai Nita-Lazar, Aditi Banerjee, Chiguang Feng, Mohammed N. Amin, Matthew B. Frieman, Wilbur H. Chen, Alan S. Cross, Lai-Xi Wang, Gerardo R. Vasta
Mol Immunol. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Mol Immunol. 2015 May; 65(1): 1–16. Published online 2015 Jan 16. doi: 10.1016/j.molimm.2014.12.010
PMCID:
PMC4344939
AbstractArticlePDF–1.9M

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