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Items: 1 to 20 of 41

1.
An angular motion of a conserved four-helix bundle facilitates alternating access transport in the TtNapA and EcNhaA transporters
Gal Masrati, Ramakanta Mondal, Abraham Rimon, Amit Kessel, Etana Padan, Erik Lindahl, Nir Ben-Tal
Proc Natl Acad Sci U S A. 2020 Dec 15; 117(50): 31850–31860. Published online 2020 Nov 30. doi: 10.1073/pnas.2002710117
PMCID:
PMC7749304
AbstractArticlePDF–2.0M
2.
Alternative proton-binding site and long-distance coupling in Escherichia coli sodium–proton antiporter NhaA
Jack A. Henderson, Yandong Huang, Oliver Beckstein, Jana Shen
Proc Natl Acad Sci U S A. 2020 Oct 13; 117(41): 25517–25522. Published online 2020 Sep 24. doi: 10.1073/pnas.2005467117
PMCID:
PMC7568328
AbstractArticlePDF–1.0M
3.
Replacement of Lys-300 with a glutamine in the NhaA Na+/H+ antiporter of Escherichia coli yields a functional electrogenic transporter
Miyer Patiño-Ruiz, Manish Dwivedi, Octavian Călinescu, Mehmet Karabel, Etana Padan, Klaus Fendler
J Biol Chem. 2019 Jan 4; 294(1): 246–256. Published online 2018 Nov 8. doi: 10.1074/jbc.RA118.004903
PMCID:
PMC6322889
AbstractArticlePDF–1.2M
4.
The role of interfacial lipids in stabilising membrane protein oligomers
Kallol Gupta, Joseph A.C. Donlan, Jonathan T.S. Hopper, Povilas Uzdavinys, Michael Landreh, Weston B. Struwe, David Drew, Andrew J. Baldwin, Phillip J. Stansfeld, Carol V. Robinson
Nature. Author manuscript; available in PMC 2017 Jul 19.
Published in final edited form as: Nature. 2017 Jan 19; 541(7637): 421–424. Published online 2017 Jan 11. doi: 10.1038/nature20820
PMCID:
PMC5501331
AbstractArticlePDF–4.4M
5.
Lysine 300 is essential for stability but not for electrogenic transport of the Escherichia coli NhaA Na+/H+ antiporter
Octavian Călinescu, Manish Dwivedi, Miyer Patiño-Ruiz, Etana Padan, Klaus Fendler
J Biol Chem. 2017 May 12; 292(19): 7932–7941. Published online 2017 Mar 22. doi: 10.1074/jbc.M117.778175
PMCID:
PMC5427271
AbstractArticlePDF–1.4M
6.
Mechanism of pH-dependent activation of the sodium-proton antiporter NhaA
Yandong Huang, Wei Chen, David L. Dotson, Oliver Beckstein, Jana Shen
Nat Commun. 2016; 7: 12940. Published online 2016 Oct 6. doi: 10.1038/ncomms12940
PMCID:
PMC5059715
AbstractArticlePDF–918K
7.
The Ec-NhaA antiporter switches from antagonistic to synergistic antiport upon a single point mutation
Manish Dwivedi, Shahar Sukenik, Assaf Friedler, Etana Padan
Sci Rep. 2016; 6: 23339. Published online 2016 Mar 29. doi: 10.1038/srep23339
PMCID:
PMC4810432
AbstractArticlePDF–2.0M
8.
NhaA antiporter functions using 10 helices, and an additional 2 contribute to assembly/stability
Etana Padan, Tsafi Danieli, Yael Keren, Dudu Alkoby, Gal Masrati, Turkan Haliloglu, Nir Ben-Tal, Abraham Rimon
Proc Natl Acad Sci U S A. 2015 Oct 13; 112(41): E5575–E5582. Published online 2015 Sep 28. doi: 10.1073/pnas.1510964112
PMCID:
PMC4611637
AbstractArticlePDF–1.3M
9.
Simulating the function of sodium/proton antiporters
Raphael Alhadeff, Arieh Warshel
Proc Natl Acad Sci U S A. 2015 Oct 6; 112(40): 12378–12383. Published online 2015 Sep 21. doi: 10.1073/pnas.1516881112
PMCID:
PMC4603454
AbstractArticlePDF–1.1M
10.
Crystal structure of the sodium–proton antiporter NhaA dimer and new mechanistic insights
Chiara Lee, Shoko Yashiro, David L. Dotson, Povilas Uzdavinys, So Iwata, Mark S.P. Sansom, Christoph von Ballmoos, Oliver Beckstein, David Drew, Alexander D. Cameron
J Gen Physiol. 2014 Dec; 144(6): 529–544. doi: 10.1085/jgp.201411219
PMCID:
PMC4242812
AbstractArticlePDF–2.9M
11.
Cotranslational folding of membrane proteins probed by arrest-peptide–mediated force measurements
Florian Cymer, Gunnar von Heijne
Proc Natl Acad Sci U S A. 2013 Sep 3; 110(36): 14640–14645. Published online 2013 Aug 19. doi: 10.1073/pnas.1306787110
PMCID:
PMC3767533
AbstractArticlePDF–607K
12.
Revealing the Ligand Binding Site of NhaA Na+/H+ Antiporter and Its pH Dependence
Michal Maes, Abraham Rimon, Lena Kozachkov-Magrisso, Assaf Friedler, Etana Padan
J Biol Chem. 2012 Nov 2; 287(45): 38150–38157. Published online 2012 Aug 22. doi: 10.1074/jbc.M112.391128
PMCID:
PMC3488084
AbstractArticlePDF–1.4M
13.
Structure-based Functional Study Reveals Multiple Roles of Transmembrane Segment IX and Loop VIII–IX in NhaA Na+/H+ Antiporter of Escherichia coli at Physiological pH
Tzvi Tzubery, Abraham Rimon, Etana Padan
J Biol Chem. 2008 Jun 6; 283(23): 15975–15987. doi: 10.1074/jbc.M800482200
PMCID:
PMC3259659
AbstractArticlePDF–1.0M
14.
Molecular aspects of bacterial pH sensing and homeostasis
Terry A. Krulwich, George Sachs, Etana Padan
Nat Rev Microbiol. Author manuscript; available in PMC 2011 Dec 29.
Published in final edited form as: Nat Rev Microbiol. 2011 May; 9(5): 330–343. Published online 2011 Apr 5. doi: 10.1038/nrmicro2549
PMCID:
PMC3247762
AbstractArticlePDF–2.7M
15.
Site-directed tryptophan fluorescence reveals two essential conformational changes in the Na+/H+ antiporter NhaA
Lena Kozachkov, Etana Padan
Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38): 15769-15774. Published online 2011 Aug 23. doi: 10.1073/pnas.1109256108
PMCID:
PMC3179058
AbstractArticlePDF–496K
16.
Alkaline pH Homeostasis in Bacteria: New Insights
Etana Padan, Eitan Bibi, Masahiro Ito, Terry A. Krulwich
Biochim Biophys Acta. Author manuscript; available in PMC 2011 Apr 8.
Published in final edited form as: Biochim Biophys Acta. 2005 Nov 30; 1717(2): 67–88. Published online 2005 Sep 26. doi: 10.1016/j.bbamem.2005.09.010
PMCID:
PMC3072713
AbstractArticlePDF–984K
17.
Transmembrane Segment II of NhaA Na+/H+ Antiporter Lines the Cation Passage, and Asp65 Is Critical for pH Activation of the Antiporter
Katia Herz, Abraham Rimon, Elena Olkhova, Lena Kozachkov, Etana Padan
J Biol Chem. 2010 Jan 15; 285(3): 2211–2220. Published online 2009 Nov 18. doi: 10.1074/jbc.M109.047134
PMCID:
PMC2804377
AbstractArticlePDF–1.6M
18.
A human Na+/H+ antiporter sharing evolutionary origins with bacterial NhaA may be a candidate gene for essential hypertension
Minghui Xiang, Mingye Feng, Sabina Muend, Rajini Rao
Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47): 18677–18681. Published online 2007 Nov 13. doi: 10.1073/pnas.0707120104
PMCID:
PMC2141836
AbstractArticlePDF–985K
19.
High-Resolution Structure of a Na+/H+ Antiporter Dimer Obtained by Pulsed Electron Paramagnetic Resonance Distance Measurements
D. Hilger, Y. Polyhach, E. Padan, H. Jung, G. Jeschke
Biophys J. 2007 Nov 15; 93(10): 3675–3683. Published online 2007 Aug 17. doi: 10.1529/biophysj.107.109769
PMCID:
PMC2072073
AbstractArticlePDF–931K
20.
How to Assemble the Parts: Structures of Protein Complexes from their Components
Albert H. Beth
Biophys J. 2007 Nov 15; 93(10): 3339. Published online 2007 Aug 17. doi: 10.1529/biophysj.107.114355
PMCID:
PMC2072061
ArticlePDF–31K

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