PMC Links for GEO Profiles (Select 55474301) - PMC

Cathrin E. Hansen, Alwin Kamermans, Kevin Mol, Kristina Berve, Carla Rodriguez-Mogeda, Wing Ka Fung, Bert van het Hof, Ruud D. Fontijn, Susanne M. A. van der Pol, Laura Michalick, Wolfgang M. Kuebler, Boyd Kenkhuis, Willeke van Roon-Mom, Wolfgang Liedtke, Britta Engelhardt, Gijs Kooij, Maarten E. Witte, Helga E. de Vries

J Neuroinflammation. 2024; 21: 72. Published online 2024 Mar 23. doi: 10.1186/s12974-024-03069-9

PMCID:: PMC10960997

Abstract Article PDF–3.3M

Select item 109492184.

Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain

Tamari Bekauri, Sarah Fischer, Kenneth V. Honn, Krishna Rao Maddipati, Tanzy Love, Chantelle Little, Ronald W. Wood, Adrienne D. Bonham, Mitchell A. Linder, David I. Yule, Chrysilla Emanuelle, Megan L. Falsetta

Pain. 2024 Apr; 165(4): 820–837. Published online 2023 Oct 26. doi: 10.1097/j.pain.0000000000003088

PMCID:: PMC10949218

Abstract Article PDF–2.1M

Select item 109168665.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 106012206.

Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity

Shuo Kong, Tao-xiang Chen, Xiang-lei Jia, Xue-lei Cheng, Meng-liu Zeng, Jing-yi Liang, Xiao-hua He, Jun Yin, Song Han, Wan-hong Liu, Yuan-teng Fan, Ting Zhou, Yu-min Liu, Bi-wen Peng

J Neuroinflammation. 2023; 20: 247. Published online 2023 Oct 25. doi: 10.1186/s12974-023-02909-4

PMCID:: PMC10601220

Abstract Article PDF–18M

Select item 105633967.

Anti-Inflammatory Role of TRPV4 in Human Macrophages

Yukiko Atsumi, Manami Toriyama, Hiroko Kato, Motoki Nakamura, Akimichi Morita, Masayuki Takaishi, Kaori Saito, Miku Tanaka, Fumihiro Okada, Makoto Tominaga, Ken J. Ishii, Fumitaka Fujita

Immunohorizons. 2023 Jan 1; 7(1): 81–96. Published online 2023 Jan 16. doi: 10.4049/immunohorizons.2200100

PMCID:: PMC10563396

Abstract Article PDF–3.5M

Select item 103001558.

Inhibition of TRPV4 remodels single cell polarity and suppresses the metastasis of hepatocellular carcinoma

Jian Liu, Yongjian Guo, Ruitian Zhang, Ye Xu, Chengju Luo, Rui Wang, Shu Xu, Libin Wei

Cell Death Dis. 2023 Jun; 14(6): 379. Published online 2023 Jun 28. doi: 10.1038/s41419-023-05903-z

PMCID:: PMC10300155

Abstract Article PDF–10M

Select item 102901249.

Structure of human TRPV4 in complex with GTPase RhoA

Kirill D. Nadezhdin, Irina A. Talyzina, Aravind Parthasarathy, Arthur Neuberger, David X. Zhang, Alexander I. Sobolevsky

Nat Commun. 2023; 14: 3733. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39346-z

PMCID:: PMC10290124

Abstract Article PDF–4.4M

Select item 1029008110.

TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease

Do Hoon Kwon, Feng Zhang, Brett A. McCray, Shasha Feng, Meha Kumar, Jeremy M. Sullivan, Wonpil Im, Charlotte J. Sumner, Seok-Yong Lee

Nat Commun. 2023; 14: 3732. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39345-0

PMCID:: PMC10290081

Abstract Article PDF–6.1M

Select item 1017844111.

Activation of the Mechanosensitive Ion Channels Piezo1 and TRPV4 in Primary Human Healthy and Osteoarthritic Chondrocytes Exhibits Ion Channel Crosstalk and Modulates Gene Expression

Bibiane Steinecker-Frohnwieser, Birgit Lohberger, Stefan Toegel, Reinhard Windhager, Veronika Glanz, Cornelia Kratschmann, Andreas Leithner, Lukas Weigl

Int J Mol Sci. 2023 May; 24(9): 7868. Published online 2023 Apr 26. doi: 10.3390/ijms24097868

PMCID:: PMC10178441

Abstract Article PDF–2.8M

Select item 1013848012.

Astrocytic TRPV4 Channels and Their Role in Brain Ischemia

Jana Tureckova, Zuzana Hermanova, Valeria Marchetti, Miroslava Anderova

Int J Mol Sci. 2023 Apr; 24(8): 7101. Published online 2023 Apr 12. doi: 10.3390/ijms24087101

PMCID:: PMC10138480

Abstract Article PDF–1.9M

Select item 1004283213.

TRPV4 channel is involved in HSV-2 infection in human vaginal epithelial cells through triggering Ca²⁺ oscillation

Ping Jiang, Song-shan Li, Xin-feng Xu, Chan Yang, Chen Cheng, Jin-shen Wang, Ping-zheng Zhou, Shu-wen Liu

Acta Pharmacol Sin. 2023 Apr; 44(4): 811–821. Published online 2022 Sep 23. doi: 10.1038/s41401-022-00975-7

PMCID:: PMC10042832

Abstract Article PDF–2.9M

Select item 995318014.

Pan-Cancer Analysis of the TRP Family, Especially TRPV4 and TRPC4, and Its Expression Correlated with Prognosis, Tumor Microenvironment, and Treatment Sensitivity

Zhenghao Chen, Youquan Zhao, Ye Tian, Rui Cao, Donghao Shang

Biomolecules. 2023 Feb; 13(2): 282. Published online 2023 Feb 2. doi: 10.3390/biom13020282

PMCID:: PMC9953180

Abstract Article PDF–6.4M

Select item 994980015.

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes

Amanda R Dicks, Grigory I Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward, Wolfgang Liedtke, Colin G Nichols, Chia-Lung Wu, Farshid Guilak

eLife. 2023; 12: e71154. Published online 2023 Feb 22. doi: 10.7554/eLife.71154

PMCID:: PMC9949800

Abstract Article PDF–9.7M

Select item 983800916.

Colonic TRPV4 overexpression is related to constipation severity

Hiroshi Mihara, Kunitoshi Uchida, Yoshiyuki Watanabe, Sohachi Nanjo, Miho Sakumura, Iori Motoo, Takayuki Ando, Masami Minemura, Jibran Sualeh Muhammad, Hiroyuki Yamamoto, Fumio Itoh, Ichiro Yasuda

BMC Gastroenterol. 2023; 23: 13. Published online 2023 Jan 13. doi: 10.1186/s12876-023-02647-0

PMCID:: PMC9838009

Abstract Article PDF–1.7M

Select item 974464617.

Characterization of TRPV4-mediated signaling pathways in an optimized human choroid plexus epithelial cell line

Louise Hulme, Alexandra Hochstetler, Christian Schwerk, Horst Schroten, Hiroshi Ishikawa, Chun-Yu Tung, Benjamin Perrin, Bonnie Blazer-Yost

Am J Physiol Cell Physiol. 2022 Dec 1; 323(6): C1823–C1842. Published online 2022 Aug 8. doi: 10.1152/ajpcell.00193.2022

PMCID:: PMC9744646

Abstract Article

Select item 957006718.

Physiological Cooperation between Aquaporin 5 and TRPV4

Kata Kira Kemény, Eszter Ducza

Int J Mol Sci. 2022 Oct; 23(19): 11634. Published online 2022 Oct 1. doi: 10.3390/ijms231911634

PMCID:: PMC9570067

Abstract Article PDF–1.3M

Select item 923660819.

Functional coupling between TRPV4 channel and TMEM16F modulates human trophoblast fusion

Yang Zhang, Pengfei Liang, Liheng Yang, Ke Zoe Shan, Liping Feng, Yong Chen, Wolfgang Liedtke, Carolyn B Coyne, Huanghe Yang

eLife. 2022; 11: e78840. Published online 2022 Jun 7. doi: 10.7554/eLife.78840

PMCID:: PMC9236608

Abstract Article PDF–5.3M

Select item 922625920.

Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4) Mitigates Seizures

Meng-liu Zeng, Jing-jing Cheng, Shuo Kong, Xing-liang Yang, Xiang-lei Jia, Xue-lei Cheng, Ling Chen, Fang-gang He, Yu-min Liu, Yuan-teng Fan, Lanzi Gongga, Tao-xiang Chen, Wan-hong Liu, Xiao-hua He, Bi-wen Peng

Neurotherapeutics. 2022 Mar; 19(2): 660–681. Published online 2022 Feb 18. doi: 10.1007/s13311-022-01198-8