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Select item 114629711.

Methyltransferase like‐14 suppresses growth and metastasis of non‐small‐cell lung cancer by decreasing LINC02747

Jiemin Wang, Shu Wang, Haopeng Yang, Ruixuan Wang, Kesong Shi, Yueshi Liu, Le Dou, Haiquan Yu

Cancer Sci. 2024 Sep; 115(9): 2931–2946. Published online 2024 Jun 18. doi: 10.1111/cas.16254

PMCID:: PMC11462971

Abstract Article PDF–17M

Select item 112211052.

METTL14 contributes to the progression of nasopharyngeal carcinoma through regulating the stability of AOC1 mRNA

Changan Hu, Shengguan Song, Shanglong Zhao, Zhen Xue, Xiwen Zhu

Hereditas. 2024; 161: 20. Published online 2024 Jul 2. doi: 10.1186/s41065-024-00317-z

PMCID:: PMC11221105

Abstract Article PDF–14M

Select item 111132603.

METTL14 affects UVB‐induced human dermal fibroblasts photoaging via miR‐100‐3p biogenesis in an m⁶A‐dependent manner

Lihao Chen, Yu Hu, Min Zhang, Lihao Liu, Jing Ma, Zhuohong Xu, Jiaan Zhang, Heng Gu, Kun Chen

Aging Cell. 2024 May; 23(5): e14123. Published online 2024 Feb 21. doi: 10.1111/acel.14123

PMCID:: PMC11113260

Abstract Article PDF–6.9M

Select item 110930244.

METTL14 decreases FTH1 mRNA stability via m6A methylation to promote sorafenib-induced ferroptosis of cervical cancer

Lijie Li, Jie Zeng, Sili He, Yanfei Yang, Chen Wang

Cancer Biol Ther. 2024; 25(1): 2349429. Published online 2024 May 13. doi: 10.1080/15384047.2024.2349429

PMCID:: PMC11093024

Abstract Article PDF–13M

Select item 110215055.

METTL14 downregulation drives S100A4⁺ monocyte-derived macrophages via MyD88/NF-κB pathway to promote MAFLD progression

Yue-fan Wang, Wen-li Zhang, Zhi-xuan Li, Yue Liu, Jian Tan, Hao-zan Yin, Zhi-chao Zhang, Xian-jie Piao, Min-hao Ruan, Zhi-hui Dai, Si-jie Wang, Chen-yang Mu, Ji-hang Yuan, Shu-han Sun, Hui Liu, Fu Yang

Signal Transduct Target Ther. 2024; 9: 91. Published online 2024 Apr 17. doi: 10.1038/s41392-024-01797-1

PMCID:: PMC11021505

Abstract Article PDF–13M

Select item 110069966.

FoxO1 promotes ovarian cancer by increasing transcription and METTL14‐mediated m⁶A modification of SMC4

Liping Tan, Shuangan Wang, Shijia Huang, Yujuan Tie, Na Sai, Yichen Mao, Shuli Zhao, Yayi Hou, Huan Dou

Cancer Sci. 2024 Apr; 115(4): 1224–1240. Published online 2024 Feb 25. doi: 10.1111/cas.16120

PMCID:: PMC11006996

Abstract Article PDF–8.1M

Select item 109400927.

METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2

Weicheng Lu, Xiaohua Yang, Weiqiang Zhong, Guojun Chen, Xinqi Guo, Qingqing Ye, Yixin Xu, Zhenhua Qi, Yaqi Ye, Jingyun Zhang, Yuge Wang, Xintong Wang, Shu Wang, Qiyue Zhao, Weian Zeng, Junting Huang, Huijie Ma, Jingdun Xie

J Clin Invest. 2024 Mar 15; 134(6): e174847. Published online 2024 Feb 6. doi: 10.1172/JCI174847

PMCID:: PMC10940092

Abstract Article PDF–13M

Select item 108447168.

METTL14 promotes IL‐6‐induced viability, glycolysis and inflammation in HaCaT cells via the m6A modification of TRIM27

Yiran Chen, Yanwei Xiang, Xiao Miao, Le Kuai, Xiaojie Ding, Tian Ma, Bin Li, Bin Fan

J Cell Mol Med. 2024 Feb; 28(3): e18085. Published online 2023 Dec 25. doi: 10.1111/jcmm.18085

PMCID:: PMC10844716

Abstract Article PDF–6.0M

Select item 108281809.

Glycolysis Induced by METTL14 Is Essential for Macrophage Phagocytosis and Phenotype in Cervical Cancer

Bingyu Wang, Zhonghao Mao, Jinwen Ye, Xinlin Jiao, Teng Zhang, Qi Wang, Sai Han, Youzhong Zhang, Chunling Wang, Taotao Dong, Baoxia Cui

J Immunol. 2024 Feb 15; 212(4): 723–736. Published online 2024 Jan 10. doi: 10.4049/jimmunol.2300339

PMCID:: PMC10828180

Abstract Article PDF–4.4M

Select item 1078394310.

Targeting key RNA methylation enzymes to improve the outcome of colorectal cancer chemotherapy (Review)

Chiyun Shao, Yanjie Han, Yuying Huang, Zhe Zhang, Tao Gong, Yajie Zhang, Xiaokang Tian, Mingzhi Fang, Xuan Han, Min Li

Int J Oncol. 2024 Feb; 64(2): 17. Published online 2023 Dec 19. doi: 10.3892/ijo.2023.5605

PMCID:: PMC10783943

Abstract Article PDF–3.3M

Select item 1075412011.

PRMT3‐Mediated Arginine Methylation of METTL14 Promotes Malignant Progression and Treatment Resistance in Endometrial Carcinoma

Yiru Wang, Can Wang, Xue Guan, Ying Ma, Shijie Zhang, Fei Li, Yue Yin, Zhenxing Sun, Xiuwei Chen, Hang Yin

Adv Sci (Weinh) 2023 Dec; 10(36): 2303812. Published online 2023 Nov 16. doi: 10.1002/advs.202303812

PMCID:: PMC10754120

Abstract Article PDF–6.0M

Select item 1064343612.

Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption

Jin-Gang Yang, Bao Sun, Zheng Wang, Xing Li, Jia-hui Gao, Jia-jun Qian, Jiang Li, Wen-jia Wei, Ping Zhang, Wei Wang

Cell Death Dis. 2023 Nov; 14(11): 738. Published online 2023 Nov 13. doi: 10.1038/s41419-023-06263-4

PMCID:: PMC10643436

Abstract Article PDF–8.2M

Select item 1055547813.

METTL14-mediated RNA methylation in digestive system tumors

Jiexuan Hu, Haishan Lin, Cong Wang, Qiang Su, Bangwei Cao

Int J Mol Med. 2023 Sep; 52(3): 86. Published online 2023 Aug 4. doi: 10.3892/ijmm.2023.5289

PMCID:: PMC10555478

Abstract Article PDF–924K

Select item 1051796814.

METTL14-upregulated miR-6858 triggers cell apoptosis in keratinocytes of oral lichen planus through decreasing GSDMC

Xiangyu Wang, Shuangting Li, Huimin Song, Yan Ding, Ruifang Gao, Xiaotong Shi, Ran Li, Xuejun Ge

Commun Biol. 2023; 6: 976. Published online 2023 Sep 23. doi: 10.1038/s42003-023-05360-6

PMCID:: PMC10517968

Abstract Article PDF–1.9M

Select item 1050020415.

METTL14 inhibits malignant progression of oral squamous cell carcinoma by targeting the autophagy-related gene RB1CC1 in an m6A-IGF2BP2-dependent manner

Jianfeng Liang, Hongshi Cai, Chen Hou, Fan Song, Yaoqi Jiang, Ziyi Wang, Danqi Qiu, Yue Zhu, Fang Wang, Dongsheng Yu, Jinsong Hou

Clin Sci (Lond) 2023 Sep; 137(17): 1373–1389. Published online 2023 Sep 5. doi: 10.1042/CS20230219

PMCID:: PMC10500204

Abstract Article PDF–8.1M

Select item 1040944216.

METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m⁶A-YTHDF2–dependent mechanism

Xiaoxue Hou, Yuwen Li, Jiali Song, Linya Peng, Wen Zhang, Rui Liu, Hui Yuan, Tiantong Feng, Jieying Li, Wenting Li, Chuanlong Zhu

Hepatol Commun. 2023 Aug; 7(8): e0199. Published online 2023 Aug 3. doi: 10.1097/HC9.0000000000000199

PMCID:: PMC10409442

Abstract Article PDF–2.0M

Select item 1023742217.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1011587518.

LncRNA UCA1 promotes keratinocyte-driven inflammation via suppressing METTL14 and activating the HIF-1α/NF-κB axis in psoriasis

Yibo Hu, Li Lei, Ling Jiang, Hongliang Zeng, Yushan Zhang, Chuhan Fu, Haoran Guo, Yumeng Dong, Yujie Ouyang, Xiaolin Zhang, Jinhua Huang, Qinghai Zeng, Jing Chen

Cell Death Dis. 2023 Apr; 14(4): 279. Published online 2023 Apr 20. doi: 10.1038/s41419-023-05790-4

PMCID:: PMC10115875

Abstract Article PDF–7.5M

Select item 998681719.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762

PMCID:: PMC9986817

Abstract Article PDF–3.5M

Select item 995044720.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x