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Select item 113786121.

Young small extracellular vesicles rejuvenate replicative senescence by remodeling Drp1 translocation-mediated mitochondrial dynamics

Yingying Peng, Tingting Zhao, Shuxuan Rong, Shuqing Yang, Wei Teng, Yunyi Xie, Yan Wang

J Nanobiotechnology. 2024; 22: 543. Published online 2024 Sep 5. doi: 10.1186/s12951-024-02818-5

PMCID:: PMC11378612

Abstract Article PDF–4.6M

Select item 113735992.

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway

Elena Prosdocimi, Veronica Carpanese, Luca Matteo Todesca, Tatiana Varanita, Magdalena Bachmann, Margherita Festa, Daniele Bonesso, Mireia Perez-Verdaguer, Andrea Carrer, Angelo Velle, Roberta Peruzzo, Silvia Muccioli, Davide Doni, Luigi Leanza, Paola Costantini, Frank Stein, Mandy Rettel, Antonio Felipe, Michael J. Edwards, Erich Gulbins, Laura Cendron, Chiara Romualdi, Vanessa Checchetto, Ildiko Szabo

Sci Adv. 2024 Sep 6; 10(36): eadn9361. Published online 2024 Sep 4. doi: 10.1126/sciadv.adn9361

PMCID:: PMC11373599

Abstract Article PDF–11M

Select item 112969143.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112169464.

Serine 39 in the GTP‐binding domain of Drp1 is involved in shaping mitochondrial morphology

Marvi Ghani, Bernadett Szabó, Mahmoud Alkhatibe, Hailemariam Amsalu, Peleg Zohar, Eszter Anna Janka, János András Mótyán, Krisztina Tar

FEBS Open Bio. 2024 Jul; 14(7): 1147–1165. Published online 2024 May 17. doi: 10.1002/2211-5463.13820

PMCID:: PMC11216946

Abstract Article PDF–14M

Select item 112099355.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111121216.

GTPBP8 modulates mitochondrial fission through a Drp1-dependent process

Xiumei He, Liang Wang, Hoi Ying Tsang, Xiaonan Liu, Xiaofeng Yang, Shiming Pu, Ziqi Guo, Cheng Yang, Qiong Wu, Zuping Zhou, Xiaobo Cen, Hongxia Zhao

J Cell Sci. 2024 Apr 15; 137(8): jcs261612. Published online 2024 Apr 30. doi: 10.1242/jcs.261612

PMCID:: PMC11112121

Abstract Article

Select item 110841097.

MAP4K4 exacerbates cardiac microvascular injury in diabetes by facilitating S-nitrosylation modification of Drp1

Yuqiong Chen, Su Li, Bo Guan, Xiaopei Yan, Chao Huang, Yingqiang Du, Fan Yang, Nannan Zhang, Yafei Li, Jian Lu, Jiankang Wang, Jun Zhang, Zhangwei Chen, Chao Chen, Xiangqing Kong

Cardiovasc Diabetol. 2024; 23: 164. Published online 2024 May 9. doi: 10.1186/s12933-024-02254-7

PMCID:: PMC11084109

Abstract Article PDF–8.9M

Select item 110730678.

Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

Parash Prasad, Sampurna Ghosh, Sib Sankar Roy

Cell Mol Life Sci. 2021 May; 78(10): 4821–4845. Published online 2021 Apr 24. doi: 10.1007/s00018-021-03818-6

PMCID:: PMC11073067

Abstract Article PDF–9.0M

Select item 109531129.

A partial Drp1 knockout improves autophagy flux independent of mitochondrial function

Rebecca Z. Fan, Carolina Sportelli, Yanhao Lai, Said S. Salehe, Jennifer R. Pinnell, Harry J. Brown, Jason R. Richardson, Shouqing Luo, Kim Tieu

Mol Neurodegener. 2024; 19: 26. Published online 2024 Mar 19. doi: 10.1186/s13024-024-00708-w

PMCID:: PMC10953112

Abstract Article PDF–12M

Select item 1094246710.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 1088115111.

Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin

Ao Liu, Anna L. Hatch, Henry N. Higgs

Mol Biol Cell. 2024 Feb 1; 35(2): ar16. Published online 2024 Jan 12. doi: 10.1091/mbc.E23-11-0427

PMCID:: PMC10881151

Abstract Article PDF–5.4M

Select item 1085882112.

Enhanced T cell immune activity mediated by Drp1 promotes the efficacy of PD-1 inhibitors in treating lung cancer

Jietao Ma, Jun Song, Xiaofang Yi, Shuling Zhang, Li Sun, Letian Huang, Chengbo Han

Cancer Immunol Immunother. 2024 Feb; 73(2): 40. Published online 2024 Feb 10. doi: 10.1007/s00262-023-03582-5

PMCID:: PMC10858821

Abstract Article PDF–3.6M

Select item 1069466413.

Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission

Kelsey A. Nolden, Megan C. Harwig, R. Blake Hill

J Biol Chem. 2023 Dec; 299(12): 105380. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105380

PMCID:: PMC10694664

Abstract Article PDF–4.1M

Select item 1065721214.

DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs

Gabriella L. Robertson, Stellan Riffle, Mira Patel, Caroline Bodnya, Andrea Marshall, Heather K. Beasley, Edgar Garza-Lopez, Jianqiang Shao, Zer Vue, Antentor Hinton, Jr, Maria S. Stoll, Sholto de Wet, Rensu P. Theart, Ram Prosad Chakrabarty, Ben Loos, Navdeep S. Chandel, Jason A. Mears, Vivian Gama

J Cell Sci. 2023 Feb 1; 136(3): jcs260370. Published online 2023 Feb 10. doi: 10.1242/jcs.260370

PMCID:: PMC10657212

Abstract Article

Select item 1064152815.

A conserved, noncanonical insert in FIS1 mediates TBC1D15 and DRP1 recruitment for mitochondrial fission

Ugochukwu K. Ihenacho, Rafael Toro, Rana H. Mansour, R. Blake Hill

J Biol Chem. 2023 Nov; 299(11): 105303. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105303

PMCID:: PMC10641528

Abstract Article PDF–7.7M

Select item 1064152416.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 1056326917.

Matrix stiffness induces Drp1-mediated mitochondrial fission through Piezo1 mechanotransduction in human intervertebral disc degeneration

Wencan Ke, Bingjin Wang, Zhiwei Liao, Yu Song, Gaocai Li, Liang Ma, Kun Wang, Shuai Li, Wenbin Hua, Cao Yang

J Transl Med. 2023; 21: 711. Published online 2023 Oct 10. doi: 10.1186/s12967-023-04590-w

PMCID:: PMC10563269

Abstract Article PDF–1.8M

Select item 1044573818.

An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity

Stephanie M. Almeida, Sofiia Ivantsiv, Rieko Niibori, Wade H. Dunham, Brooke A. Green, Liang Zhao, Anne-Claude Gingras, Sabine P. Cordes

Dis Model Mech. 2023 Aug 1; 16(8): dmm049762. Published online 2023 Aug 17. doi: 10.1242/dmm.049762

PMCID:: PMC10445738

Abstract Article

Select item 1042737519.

YY2‐DRP1 Axis Regulates Mitochondrial Fission and Determines Cancer Stem Cell Asymmetric Division

Mankun Wei, Uli Nurjanah, Juan Li, Xinxin Luo, Rendy Hosea, Yanjun Li, Jianting Zeng, Wei Duan, Guanbin Song, Makoto Miyagishi, Vivi Kasim, Shourong Wu

Adv Sci (Weinh) 2023 Aug; 10(23): 2207349. Published online 2023 Jun 9. doi: 10.1002/advs.202207349

PMCID:: PMC10427375

Abstract Article PDF–8.2M

Select item 1037865620.

The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases

Pierce Colpman, Asish Dasgupta, Stephen L. Archer

Cells. 2023 Jul; 12(14): 1897. Published online 2023 Jul 20. doi: 10.3390/cells12141897

PMCID:: PMC10378656

Abstract Article PDF–4.9M

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