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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 107649582.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 107611033.

Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation

Zhiya Deng, Man He, Hongbin Hu, Wenqian Zhang, Yaoyuan Zhang, Yue Ge, Tongtong Ma, Jie Wu, Lulan Li, Maomao Sun, Sheng An, Jiaxin Li, Qiaobing Huang, Shenhai Gong, Jiaxing Zhang, Zhongqing Chen, Zhenhua Zeng

Autophagy. 2024; 20(1): 151–165. Published online 2023 Aug 31. doi: 10.1080/15548627.2023.2252265

PMCID:: PMC10761103

Abstract Article PDF–3.9M

Select item 104860654.

Altered H3K4me3 profile at the TFAM promoter causes mitochondrial alterations in preadipocytes from first-degree relatives of type 2 diabetics

Michele Longo, Federica Zatterale, Rosa Spinelli, Jamal Naderi, Luca Parrillo, Pasqualina Florese, Cecilia Nigro, Alessia Leone, Augusta Moccia, Antonella Desiderio, Gregory A. Raciti, Claudia Miele, Ulf Smith, Francesco Beguinot

Clin Epigenetics. 2023; 15: 144. Published online 2023 Sep 7. doi: 10.1186/s13148-023-01556-z

PMCID:: PMC10486065

Abstract Article PDF–6.2M

Select item 104700785.

Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy

Mansoor Hussain, Aftab Mohammed, Shabnam Saifi, Swati Priya, Sagar Sengupta

J Biol Chem. 2023 Sep; 299(9): 105087. Published online 2023 Jul 24. doi: 10.1016/j.jbc.2023.105087

PMCID:: PMC10470078

Abstract Article PDF–5.1M

Select item 104696126.

High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA

Liuyiqi Jiang, Mu Xiao, Qing-Qing Liao, Luqian Zheng, Chunyan Li, Yuemei Liu, Bing Yang, Aiming Ren, Chao Jiang, Xin-Hua Feng

mSystems. 2023 Jul-Aug; 8(4): e00135-23. Published online 2023 Jun 14. doi: 10.1128/msystems.00135-23

PMCID:: PMC10469612

Abstract Article PDF–4.0M

Select item 104627117.

SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

Augusto C. Montezano, Livia L. Camargo, Sheon Mary, Karla B Neves, Francisco J Rios, Ross Stein, Rheure A. Lopes, Wendy Beattie, Jacqueline Thomson, Vanessa Herder, Agnieszka M. Szemiel, Steven McFarlane, Massimo Palmarini, Rhian M. Touyz

Sci Rep. 2023; 13: 14086. Published online 2023 Aug 28. doi: 10.1038/s41598-023-41115-3

PMCID:: PMC10462711

Abstract Article PDF–1.3M

Select item 102794728.

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways

Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett

Cell Rep. Author manuscript; available in PMC 2023 Jun 19.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496

PMCID:: PMC10279472

Abstract Article PDF–2.9M

Select item 102536929.

The C-Terminal Tail of Mitochondrial Transcription Factor A Is Dispensable for Mitochondrial DNA Replication and Transcription In Situ

Natalya Kozhukhar, Mikhail F. Alexeyev

Int J Mol Sci. 2023 Jun; 24(11): 9430. Published online 2023 May 29. doi: 10.3390/ijms24119430

PMCID:: PMC10253692

Abstract Article PDF–1.5M

Select item 1019896310.

The Key Amino Acid Residues of Mitochondrial Transcription Factor A (TFAM) Synergize with Abasic (AP) Site Dynamics to Facilitate AP-Lyase Reactions

Wenxin Zhao, Wenyan Xu, Jin Tang, Shivansh Kaushik, Chia-En A. Chang, Linlin Zhao

ACS Chem Biol. Author manuscript; available in PMC 2024 May 19.

Published in final edited form as: ACS Chem Biol. 2023 May 19; 18(5): 1168–1179. Published online 2023 Mar 17. doi: 10.1021/acschembio.3c00047

PMCID:: PMC10198963

Abstract Article PDF–1.1M

Select item 1015161511.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1006740512.

Downregulated mitochondrial transcription factor A enhances mycoplasma infection to promote the metastasis of hepatocellular carcinoma

Yinping Wang, Gang Wang, Xin Hong, Jing Zhao, Dan Wu, Lin Chen, Xiaoli Liu, Deyu Kong, Qichao Huang, Jinliang Xing, Nan Wang, Yilin Zhao

Cancer Sci. 2023 Apr; 114(4): 1464–1478. Published online 2023 Feb 15. doi: 10.1111/cas.15715

PMCID:: PMC10067405

Abstract Article PDF–59M

Select item 997294513.

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2

Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang

J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22

PMCID:: PMC9972945

Abstract Article PDF–3.0M

Select item 995044714.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 990204715.

Identifying Mitochondrial Transcription Factor A As a Potential Biomarker for the Carcinogenesis and Prognosis of Prostate Cancer

Yaqiong Tian, Zhijuan Fan, Shuang Liu, Yujing Wu, Shuye Liu

Genet Test Mol Biomarkers. January 2023; 27(1): 5–11. Published online 2023 Jan 31. doi: 10.1089/gtmb.2022.0141

Correction in:: Genet Test Mol Biomarkers. June 2023; 27(6): 202.

PMCID:: PMC9902047

Abstract Article PDF–539K

Select item 988113616.

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke

Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188

PMCID:: PMC9881136

Abstract Article PDF–4.4M

Select item 986517317.

C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson’s Disease

Ana Sierra-Magro, Fernando Bartolome, David Lozano-Muñoz, Jesús Alarcón-Gil, Elena Gine, Marina Sanz-SanCristobal, Sandra Alonso-Gil, Marta Cortes-Canteli, Eva Carro, Ana Pérez-Castillo, José A. Morales-García

Int J Mol Sci. 2023 Jan; 24(2): 1459. Published online 2023 Jan 11. doi: 10.3390/ijms24021459

PMCID:: PMC9865173

Abstract Article PDF–6.6M

Select item 984140718.

DNA–protein cross-links between abasic DNA damage and mitochondrial transcription factor A (TFAM)

Wenyan Xu, Jin Tang, Linlin Zhao

Nucleic Acids Res. 2023 Jan 11; 51(1): 41–53. Published online 2022 Dec 30. doi: 10.1093/nar/gkac1214

PMCID:: PMC9841407

Abstract Article PDF–2.7M

Select item 977255819.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 970808620.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676