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Items: 1 to 20 of 265

1.
Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure
Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer
Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y
PMCID:
PMC11447256
AbstractArticlePDF–2.8M
2.
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
PMCID:
PMC11315929
AbstractArticlePDF–3.4M
3.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
4.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
5.
Uncovering potential diagnostic and pathophysiological roles of α‐synuclein and DJ‐1 in melanoma
Agathe Quesnel, Leya Danielle Martin, Chaimaa Tarzi, Vasileios P. Lenis, Nathan Coles, Meez Islam, Claudio Angione, Tiago F. Outeiro, Ahmad A. Khundakar, Panagiota S. Filippou
Cancer Med. 2024 Jan; 13(1): e6900. Published online 2024 Jan 8. doi: 10.1002/cam4.6900
PMCID:
PMC10807602
AbstractArticlePDF–9.8M
6.
DJ-1: A Potential Biomarker Related to Prognosis, Chemoresistance, and Expression of Microenvironmental Chemokine in HR-Positive Breast Cancer
Yinghong Xie, Yuancheng Li, Mengzhu Yang
J Immunol Res. 2023; 2023: 5041223. Published online 2023 Dec 13. doi: 10.1155/2023/5041223
PMCID:
PMC10732869
AbstractArticlePDF–5.7M
7.
TrkB inhibition of DJ-1 degradation promotes the growth and maintenance of cancer stem cell characteristics in hepatocellular carcinoma
Min Soo Kim, Won Sung Lee, Wook Jin
Cell Mol Life Sci. 2023 Oct; 80(10): 303. Published online 2023 Sep 25. doi: 10.1007/s00018-023-04960-z
PMCID:
PMC10520132
AbstractArticlePDF–2.6M
8.
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains
Julia Jülg, Dieter Edbauer, Christian Behrends
EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895
PMCID:
PMC10398660
AbstractArticlePDF–2.4M
9.
Disease-Modifying Effects of Vincamine Supplementation in Drosophila and Human Cell Models of Parkinson’s Disease Based on DJ-1 Deficiency
Francisco José Sanz, Cristina Solana-Manrique, Nuria Paricio
ACS Chem Neurosci. 2023 Jun 21; 14(12): 2294–2301. Published online 2023 Jun 8. doi: 10.1021/acschemneuro.3c00026
PMCID:
PMC10288506
AbstractArticlePDF–2.7M
10.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
11.
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage
Fengli Wang, Lingjuan Wang, Shiming Gan, Shenglei Feng, Sijin Ouyang, Xiaoli Wang, Shuiqiao Yuan
Research (Wash D C) 2023; 6: 0091. Published online 2023 Apr 12. doi: 10.34133/research.0091
PMCID:
PMC10202183
AbstractArticlePDF–18M
12.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
13.
Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ‐1
Joonhyeok Choi, Sungho Tak, Hoe‐Myung Jung, Soyoung Cha, Eunha Hwang, Donghan Lee, Joon‐Hwa Lee, Kyoung‐Seok Ryu, Chankyu Park
Protein Sci. 2023 May; 32(5): e4641. Published online 2023 May 1. doi: 10.1002/pro.4641
PMCID:
PMC10127264
AbstractArticlePDF–2.6M
14.
PARK7/DJ-1 in microglia: implications in Parkinson’s disease and relevance as a therapeutic target
Frida Lind-Holm Mogensen, Andrea Scafidi, Aurélie Poli, Alessandro Michelucci
J Neuroinflammation. 2023; 20: 95. Published online 2023 Apr 18. doi: 10.1186/s12974-023-02776-z
PMCID:
PMC10111685
AbstractArticlePDF–1.9M
15.
Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation
Qingzeng Gao, Jeremiah W. Jacob-Dolan, Rebecca A. Scheck
Biochemistry. 2023 Mar 21; 62(6): 1181–1190. Published online 2023 Feb 23. doi: 10.1021/acs.biochem.3c00028
PMCID:
PMC10035033
AbstractArticlePDF–10M
16.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
17.
Searching for Biomarkers in the Blood of Patients at Risk of Developing Parkinson’s Disease at the Prodromal Stage
Elena A. Katunina, Victor Blokhin, Marina R. Nodel, Ekaterina N. Pavlova, Alexander L. Kalinkin, Valerian G. Kucheryanu, Leyla Alekperova, Marianna V. Selikhova, Mikhail Yu. Martynov, Michael V. Ugrumov
Int J Mol Sci. 2023 Feb; 24(3): 1842. Published online 2023 Jan 17. doi: 10.3390/ijms24031842
PMCID:
PMC9915927
AbstractArticlePDF–5.3M
18.
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy
Dorien Imberechts, Inge Kinnart, Fieke Wauters, Joanne Terbeek, Liselot Manders, Keimpe Wierda, Kristel Eggermont, Rodrigo Furtado Madeiro, Carolyn Sue, Catherine Verfaillie, Wim Vandenberghe
Brain. 2022 Dec; 145(12): 4368–4384. Published online 2022 Aug 30. doi: 10.1093/brain/awac313
PMCID:
PMC9762950
AbstractArticlePDF–2.0M
19.
MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer
Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang
Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x
PMCID:
PMC9523997
AbstractArticlePDF–6.9M
20.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein
Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg, John D. Gross, Nevan J. Krogan, Keith R. Jerome, Birgit Schilling, Melanie Ott, Eric Verdin
PLoS Pathog. 2022 Sep; 18(9): e1010811. Published online 2022 Sep 12. doi: 10.1371/journal.ppat.1010811
PMCID:
PMC9499238
AbstractArticlePDF–3.7M

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