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Items: 1 to 20 of 55

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development
Qihang Sun, Jiani Li, Jingyu Ma, Yuxing Zheng, Rong Ju, Xuri Li, Xiangrong Ren, Lijuan Huang, Rongyuan Chen, Xuhua Tan, Lixia Luo
Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 15. Published online 2023 Dec 14. doi: 10.1167/iovs.64.15.15
PMCID:
PMC10723223
AbstractArticlePDF–36M
3.
ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment
Jiawen Xiang, Anthony J. Pompetti, Adam P. Faranda, Yan Wang, Samuel G. Novo, David Wan-Cheng Li, Melinda K. Duncan
Cells. 2023 Nov; 12(22): 2636. Published online 2023 Nov 16. doi: 10.3390/cells12222636
PMCID:
PMC10670291
AbstractArticlePDF–9.2M
4.
The aging mouse lens transcriptome
Adam P. Faranda, Mahbubul H. Shihan, Yan Wang, Melinda K. Duncan
Exp Eye Res. Author manuscript; available in PMC 2022 Aug 1.
Published in final edited form as: Exp Eye Res. 2021 Aug; 209: 108663. Published online 2021 Jun 11. doi: 10.1016/j.exer.2021.108663
PMCID:
PMC8720273
AbstractArticlePDF–1.8M
5.
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia
Sharmilee Vetrivel, Natascia Tiso, Andrea Kügler, Martin Irmler, Marion Horsch, Johannes Beckers, Daniela Hladik, Florian Giesert, Valerie Gailus-Durner, Helmut Fuchs, Sibylle Sabrautzki, Martin Hrabě de Angelis, Jochen Graw
Exp Eye Res. 2019 Nov; 188: 107632. doi: 10.1016/j.exer.2019.03.024
PMCID:
PMC6876282
AbstractArticle
6.
Lens-specific deletion of the Msx2 gene increased apoptosis by enhancing the caspase-3/caspase-8 signaling pathway
Ziyan Yu, Wenting Yu, Jia Liu, Danhong Wu, Chunxia Wang, Jinsong Zhang, Jiangyue Zhao
J Int Med Res. 2018 Jul; 46(7): 2843–2855. Published online 2018 Jun 19. doi: 10.1177/0300060518774687
PMCID:
PMC6124292
AbstractArticlePDF–1.1M
7.
Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens
Mina Azimi, Tien T. Le, Nadean L. Brown
Differentiation. Author manuscript; available in PMC 2019 Jul 25.
Published in final edited form as: Differentiation. 2018 Jul-Aug; 102: 40–52. Published online 2018 Jul 25. doi: 10.1016/j.diff.2018.07.003
PMCID:
PMC6089524
AbstractArticlePDF–3.6M
8.
Crk proteins transduce FGF signaling to promote lens fiber cell elongation
Tamica N Collins, Yingyu Mao, Hongge Li, Michael Bouaziz, Angela Hong, Gen-Sheng Feng, Fen Wang, Lawrence A Quilliam, Lin Chen, Taeju Park, Tom Curran, Xin Zhang
eLife. 2018; 7: e32586. Published online 2018 Jan 23. doi: 10.7554/eLife.32586
PMCID:
PMC5818251
AbstractArticlePDF–8.2M
9.
β1-integrin controls cell fate specification in early lens development
Mallika Pathania, Yan Wang, Vladimir N. Simirskii, Melinda K. Duncan
Differentiation. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Differentiation. 2016 Oct-Nov; 92(4): 133–147. Published online 2016 Sep 3. doi: 10.1016/j.diff.2016.08.002
PMCID:
PMC5159248
AbstractArticlePDF–2.8M
10.
The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6
Barbora Antosova, Jana Smolikova, Lucie Klimova, Jitka Lachova, Michaela Bendova, Iryna Kozmikova, Ondrej Machon, Zbynek Kozmik
PLoS Genet. 2016 Dec; 12(12): e1006441. Published online 2016 Dec 5. doi: 10.1371/journal.pgen.1006441
PMCID:
PMC5137874
AbstractArticlePDF–2.7M
11.
Disruption of Rest Leads to the Early Onset of Cataracts with the Aberrant Terminal Differentiation of Lens Fiber Cells
Hitomi Aoki, Hajime Ogino, Hiroyuki Tomita, Akira Hara, Takahiro Kunisada
PLoS One. 2016; 11(9): e0163042. Published online 2016 Sep 15. doi: 10.1371/journal.pone.0163042
PMCID:
PMC5025245
AbstractArticlePDF–4.2M
12.
Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation
Shuying He, Saima Limi, Rebecca S. McGreal, Qing Xie, Lisa A. Brennan, Wanda Lee Kantorow, Juraj Kokavec, Romit Majumdar, Harry Hou, Jr, Winfried Edelmann, Wei Liu, Ruth Ashery-Padan, Jiri Zavadil, Marc Kantorow, Arthur I. Skoultchi, Tomas Stopka, Ales Cvekl
Development. 2016 Jun 1; 143(11): 1937–1947. doi: 10.1242/dev.135285
PMCID:
PMC4920164
AbstractArticle
13.
FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
Shahid Y. Khan, Shivakumar Vasanth, Firoz Kabir, John D. Gottsch, Arif O. Khan, Raghothama Chaerkady, Mei-Chong W. Lee, Carmen C. Leitch, Zhiwei Ma, Julie Laux, Rafael Villasmil, Shaheen N. Khan, Sheikh Riazuddin, Javed Akram, Robert N. Cole, C. Conover Talbot, Nader Pourmand, Norann A. Zaghloul, J. Fielding Hejtmancik, S. Amer Riazuddin
Nat Commun. 2016; 7: 10953. Published online 2016 Mar 24. doi: 10.1038/ncomms10953
PMCID:
PMC4820811
AbstractArticlePDF–2.6M
14.
FOXE3 mutations predispose to thoracic aortic aneurysms and dissections
Shao-Qing Kuang, Olga Medina-Martinez, Dong-chuan Guo, Limin Gong, Ellen S. Regalado, Corey L. Reynolds, Catherine Boileau, Guillaume Jondeau, Siddharth K. Prakash, Callie S. Kwartler, Lawrence Yang Zhu, Andrew M. Peters, Xue-Yan Duan, National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) Investigators, National Heart, Lung, and Blood Institute (NHLBI) Grand Opportunity (GO) Exome Sequencing Project (ESP), Michael J. Bamshad, Jay Shendure, Debbie A. Nickerson, Regie L. Santos-Cortez, Xiurong Dong, Suzanne M. Leal, Mark W. Majesky, Eric C. Swindell, Milan Jamrich, Dianna M. Milewicz
J Clin Invest. 2016 Mar 1; 126(3): 948–961. Published online 2016 Feb 8. doi: 10.1172/JCI83778
PMCID:
PMC4767350
AbstractArticlePDF–6.3M
15.
Deficiency of the RNA binding protein Caprin2 causes lens defects and features of Peters anomaly
Soma Dash, Christine A. Dang, David C. Beebe, Salil A. Lachke
Dev Dyn. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: Dev Dyn. 2015 Oct; 244(10): 1313–1327. Published online 2015 Aug 7. doi: 10.1002/dvdy.24303
PMCID:
PMC4586403
AbstractArticlePDF–2.2M
16.
Bmp4 from the Optic Vesicle Specifies Murine Retina Formation
Jie Huang, Ying Liu, Alina Oltean, David C. Beebe
Dev Biol. Author manuscript; available in PMC 2016 Jun 1.
Published in final edited form as: Dev Biol. 2015 Jun 1; 402(1): 119–126. Published online 2015 Mar 16. doi: 10.1016/j.ydbio.2015.03.006
PMCID:
PMC4523094
AbstractArticlePDF–2.2M
17.
Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract
Smriti A. Agrawal, Deepti Anand, Archana D. Siddam, Atul Kakrana, Soma Dash, David A. Scheiblin, Christine A. Dang, Anne M. Terrell, Stephanie M. Waters, Abhyudai Singh, Hozumi Motohashi, Masayuki Yamamoto, Salil A. Lachke
Hum Genet. Author manuscript; available in PMC 2016 Jul 1.
Published in final edited form as: Hum Genet. 2015 Jul; 134(7): 717–735. Published online 2015 Apr 21. doi: 10.1007/s00439-015-1554-5
PMCID:
PMC4486474
AbstractArticlePDF–4.4M
18.
Fibroblast growth factor receptor 1 (Fgfr1) is not required for lens fiber differentiation in mice
Haotian Zhao, Ying Yang, Juha Partanen, Brian Ciruna, Janet Rossant, Michael L. Robinson
Mol Vis. Author manuscript; available in PMC 2014 Dec 30.
Published in final edited form as: Mol Vis. 2006; 12: 15–25. Published online 2006 Jan 10.
PMCID:
PMC4280232
AbstractArticlePDF–1.1M
19.
Expression of Truncated PITX3 in the Developing Lens Leads to Microphthalmia and Aphakia in Mice
Kenta Wada, Yoshibumi Matsushima, Tomoki Tada, Sayaka Hasegawa, Yo Obara, Yasuhiro Yoshizawa, Gou Takahashi, Hiroshi Hiai, Midori Shimanuki, Sari Suzuki, Junichi Saitou, Naoki Yamamoto, Masumi Ichikawa, Kei Watanabe, Yoshiaki Kikkawa
PLoS One. 2014; 9(10): e111432. Published online 2014 Oct 27. doi: 10.1371/journal.pone.0111432
PMCID:
PMC4210183
AbstractArticlePDF–12M
20.
Peroxidasin is essential for eye development in the mouse
Xiaohe Yan, Sibylle Sabrautzki, Marion Horsch, Helmut Fuchs, Valerie Gailus-Durner, Johannes Beckers, Martin Hrabě de Angelis, Jochen Graw
Hum Mol Genet. 2014 Nov 1; 23(21): 5597–5614. Published online 2014 Jun 3. doi: 10.1093/hmg/ddu274
PMCID:
PMC4189897
AbstractArticlePDF–42M

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