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Select item 112916421.

A GABAergic system in atrioventricular node pacemaker cells controls electrical conduction between the atria and ventricles

Dandan Liang, Liping Zhou, Huixing Zhou, Fulei Zhang, Guojian Fang, Junwei Leng, Yahan Wu, Yuemei Zhang, Anqi Yang, Yi Liu, Yi-Han Chen

Cell Res. 2024 Aug; 34(8): 556–571. Published online 2024 Jun 7. doi: 10.1038/s41422-024-00980-x

PMCID:: PMC11291642

Abstract Article PDF–7.2M

Select item 111841472.

Region and layer-specific expression of GABA_A receptor isoforms and KCC2 in developing cortex

Kirill Zavalin, Anjana Hassan, Yueli Zhang, Zain Khera, Andre H. Lagrange

Front Cell Neurosci. 2024; 18: 1390742. Published online 2024 Jun 4. doi: 10.3389/fncel.2024.1390742

PMCID:: PMC11184147

Abstract Article PDF–17M

Select item 107693503.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 102721394.

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice

Hyoseon Oh, Suho Lee, Yusang Oh, Seongbin Kim, Young Seo Kim, Yeji Yang, Woochul Choi, Ye-Eun Yoo, Heejin Cho, Seungjoon Lee, Esther Yang, Wuhyun Koh, Woojin Won, Ryunhee Kim, C. Justin Lee, Hyun Kim, Hyojin Kang, Jin Young Kim, Taeyun Ku, Se-Bum Paik, Eunjoon Kim

Nat Commun. 2023; 14: 3547. Published online 2023 Jun 15. doi: 10.1038/s41467-023-39203-z

PMCID:: PMC10272139

Abstract Article PDF–4.3M

Select item 102089585.

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome

Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh

Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5

PMCID:: PMC10208958

Abstract Article PDF–7.0M

Select item 96488066.

Gabrb2 knock-out mice exhibit double-directed PMDD-like symptoms: GABAAR subunits, neurotransmitter metabolism disruption, and allopregnanolone binding

Mingzhou Gao, Hao Zhang, Ya Sun, Zhan Gao, Chunyan Sun, Fengqin Wei, Dongmei Gao

Aging (Albany NY) 2022 Oct 31; 14(20): 8437–8447. Published online 2022 Oct 24. doi: 10.18632/aging.204351

PMCID:: PMC9648806

Abstract Article PDF–939K

Select item 83802147.

GABA_A receptors: structure, function, pharmacology, and related disorders

Amr Ghit, Dina Assal, Ahmed S. Al-Shami, Diaa Eldin E. Hussein

J Genet Eng Biotechnol. 2021 Dec; 19: 123. Published online 2021 Aug 21. doi: 10.1186/s43141-021-00224-0

PMCID:: PMC8380214

Abstract Article PDF–1016K

Select item 83132398.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 76125939.

Differential assembly diversifies GABA_A receptor structures and signalling

Andrija Sente, Rooma Desai, Katerina Naydenova, Tomas Malinauskas, Youssef Jounaidi, Jonas Miehling, Xiaojuan Zhou, Simonas Masiulis, Steven W. Hardwick, Dimitri Y. Chirgadze, Keith W. Miller, A. Radu Aricescu

Nature. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Nature. 2022 Apr 1; 604(7904): 190–194. Published online 2022 Mar 30. doi: 10.1038/s41586-022-04517-3

PMCID:: PMC7612593

Abstract Article PDF–5.7M

Select item 687974710.

Protrudin modulates seizure activity through GABA_A receptor regulation

Xi Lu, Yong Yang, Ruijiao Zhou, Yun Li, Yi Yang, Xuefeng Wang

Cell Death Dis. 2019 Dec; 10(12): 897. Published online 2019 Nov 27. doi: 10.1038/s41419-019-2118-8

PMCID:: PMC6879747

Abstract Article PDF–3.2M

Select item 678306511.

Migration Defects of cdk5^−/− Neurons in the Developing Cerebellum is Cell Autonomous

Toshio Ohshima, Edward C. Gilmore, Glenn Longenecker, David M. Jacobowitz, Roscoe O. Brady, Karl Herrup, Ashok B. Kulkarni

J Neurosci. 1999 Jul 15; 19(14): 6017–6026. doi: 10.1523/JNEUROSCI.19-14-06017.1999

PMCID:: PMC6783065

Abstract Article PDF–2.5M

Select item 676247412.

Loss of the Major GABA_A Receptor Subtype in the Brain Is Not Lethal in Mice

Cyrille Sur, Keith A. Wafford, David S. Reynolds, Karen L. Hadingham, Frances Bromidge, Alison Macaulay, Neil Collinson, Gillian O'Meara, Owain Howell, Richard Newman, Janice Myers, John R. Atack, Gerard R. Dawson, Ruth M. McKernan, Paul J. Whiting, Thomas W. Rosahl

J Neurosci. 2001 May 15; 21(10): 3409–3418. doi: 10.1523/JNEUROSCI.21-10-03409.2001

PMCID:: PMC6762474

Abstract Article PDF–687K

Select item 675795613.

No Ligand Binding in the GB2 Subunit of the GABA_BReceptor Is Required for Activation and Allosteric Interaction between the Subunits

Julie Kniazeff, Thierry Galvez, Gilles Labesse, Jean-Philippe Pin

J Neurosci. 2002 Sep 1; 22(17): 7352–7361. doi: 10.1523/JNEUROSCI.22-17-07352.2002

PMCID:: PMC6757956

Abstract Article PDF–1015K

Select item 674190114.

Interaction of Calcineurin and Type-A GABA Receptor γ₂ Subunits Produces Long-Term Depression at CA1 Inhibitory Synapses

Jian Wang, ShuHong Liu, Ursula Haditsch, WeiHong Tu, Kimberley Cochrane, Gholamreza Ahmadian, Linda Tran, Jadine Paw, YuTian Wang, Isabelle Mansuy, Michael M. Salter, YouMing Lu

J Neurosci. 2003 Feb 1; 23(3): 826–836. doi: 10.1523/JNEUROSCI.23-03-00826.2003

PMCID:: PMC6741901

Abstract Article PDF–571K

Select item 674036715.

Sedation and Anesthesia Mediated by Distinct GABA_A Receptor Isoforms

David S. Reynolds, Thomas W. Rosahl, Jennifer Cirone, Gillian F. O'Meara, Alison Haythornthwaite, Richard J. Newman, Janice Myers, Cyrille Sur, Owain Howell, A. Richard Rutter, John Atack, Alison J. Macaulay, Karen L. Hadingham, Peter H. Hutson, Delia Belelli, Jeremy J. Lambert, Gerard R. Dawson, Ruth McKernan, Paul J. Whiting, Keith A. Wafford

J Neurosci. 2003 Sep 17; 23(24): 8608–8617. doi: 10.1523/JNEUROSCI.23-24-08608.2003