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Items: 1 to 20 of 265

1.
Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells
Cheng Qian, Ying Xin, Cheng Qi, Hui Wang, Bryan C. Dong, Donald J. Zack, Seth Blackshaw, Samer Hattar, Feng-Quan Zhou, Jiang Qian
Nat Commun. 2024; 15: 2206. Published online 2024 Mar 11. doi: 10.1038/s41467-024-46428-z
PMCID:
PMC11636819
AbstractArticlePDF–12M
2.
Deciphering autism heterogeneity: a molecular stratification approach in four mouse models
Caroline Gora, Ana Dudas, Océane Vaugrente, Lucile Drobecq, Emmanuel Pecnard, Gaëlle Lefort, Lucie P. Pellissier
Transl Psychiatry. 2024; 14: 416. Published online 2024 Oct 4. doi: 10.1038/s41398-024-03113-5
PMCID:
PMC11452541
AbstractArticlePDF–1.3M
3.
Selective targeting of mu opioid receptors to primary cilia
Rita R. Fagan, David F. Lee, Matan Geron, Grégory Scherrer, Mark von Zastrow, Aliza T. Ehrlich
Cell Rep. Author manuscript; available in PMC 2024 Jul 18.
Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114164. Published online 2024 Apr 27. doi: 10.1016/j.celrep.2024.114164
PMCID:
PMC11257377
AbstractArticlePDF–2.2M
4.
Parabrachial Calca neurons drive nociplasticity
Logan F. Condon, Ying Yu, Sekun Park, Feng Cao, Jordan L. Pauli, Tyler S. Nelson, Richard D. Palmiter
Cell Rep. Author manuscript; available in PMC 2024 Jun 27.
Published in final edited form as: Cell Rep. 2024 Apr 23; 43(4): 114057. Published online 2024 Apr 6. doi: 10.1016/j.celrep.2024.114057
PMCID:
PMC11210282
AbstractArticlePDF–1.5M
5.
Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation
Susan T. Lubejko, Giulia Livrizzi, Stanley A. Buczynski, Janki Patel, Jean C. Yung, Tony L. Yaksh, Matthew R. Banghart
Sci Adv. 2024 Apr 26; 10(17): eadj9581. Published online 2024 Apr 26. doi: 10.1126/sciadv.adj9581
PMCID:
PMC11051679
AbstractArticlePDF–3.6M
6.
Opioidergic signaling contributes to food-mediated suppression of AgRP neurons
Nilufer Sayar-Atasoy, Yavuz Yavuz, Connor Laule, Chunyang Dong, Hyojin Kim, Jacob Rysted, Kyle Flippo, Debbie Davis, Iltan Aklan, Bayram Yilmaz, Lin Tian, Deniz Atasoy
Cell Rep. Author manuscript; available in PMC 2024 Feb 14.
Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113630. Published online 2024 Jan 1. doi: 10.1016/j.celrep.2023.113630
PMCID:
PMC10865729
AbstractArticlePDF–2.4M
7.
A CHOLINERGIC CIRCUIT THAT RELIEVES PAIN, DESPITE OPIOID TOLERANCE
Shivang Sullere, Alissa Kunczt, Daniel S McGehee
Neuron. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: Neuron. 2023 Nov 1; 111(21): 3414–3434.e15. Published online 2023 Sep 20. doi: 10.1016/j.neuron.2023.08.017
PMCID:
PMC10843525
AbstractArticlePDF–3.4M
8.
Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms
Arjun Muralidharan, Alexander Samoshkin, Marino Convertino, Marjo Hannele Piltonen, Pavel Gris, Jian Wang, Changyu Jiang, Richard Klares, III, Alexander Linton, Ru-Rong Ji, William Maixner, Nikolay V. Dokholyan, Jeffrey S. Mogil, Luda Diatchenko
Br J Pharmacol. Author manuscript; available in PMC 2023 Dec 5.
Published in final edited form as: Br J Pharmacol. 2021 Jul; 178(13): 2709–2726. Published online 2021 Apr 30. doi: 10.1111/bph.15463
PMCID:
PMC10697213
AbstractArticlePDF–2.1M
9.
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types
Gregory J. Salimando, Sébastien Tremblay, Blake A. Kimmey, Jia Li, Sophie A. Rogers, Jessica A. Wojick, Nora M. McCall, Lisa M. Wooldridge, Amrith Rodrigues, Tito Borner, Kristin L. Gardiner, Selwyn S. Jayakar, Ilyas Singeç, Clifford J. Woolf, Matthew R. Hayes, Bart C. De Jonghe, F. Christian Bennett, Mariko L. Bennett, Julie A. Blendy, Michael L. Platt, Kate Townsend Creasy, William R. Renthal, Charu Ramakrishnan, Karl Deisseroth, Gregory Corder
Nat Commun. 2023; 14: 5632. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41407-2
PMCID:
PMC10499891
AbstractArticlePDF–16M
10.
Nitro-benzylideneoxymorphone, a bifunctional mu and delta opioid receptor ligand with high mu opioid receptor efficacy
Keith M. Olson, Andrea L. Devereaux, Payal Chatterjee, Savanah L. Saldaña-Shumaker, Amanda Shafer, Adam Plotkin, Ram Kandasamy, Alexander D. MacKerell, Jr., John R. Traynor, Christopher W. Cunningham
Front Pharmacol. 2023; 14: 1230053. Published online 2023 Jul 3. doi: 10.3389/fphar.2023.1230053
PMCID:
PMC10352325
AbstractArticlePDF–3.3M
11.
Structure-based design of bitopic ligands for the μ-opioid receptor
Abdelfattah Faouzi, Haoqing Wang, Saheem A. Zaidi, Jeffrey F. DiBerto, Tao Che, Qianhui Qu, Michael J. Robertson, Manish K. Madasu, Amal El Daibani, Balazs R. Varga, Tiffany Zhang, Claudia Ruiz, Shan Liu, Jin Xu, Kevin Appourchaux, Samuel T. Slocum, Shainnel O. Eans, Michael D. Cameron, Ream Al-Hasani, Ying Xian Pan, Bryan L. Roth, Jay P. McLaughlin, Georgios Skiniotis, Vsevolod Katritch, Brian K. Kobilka, Susruta Majumdar
Nature. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Nature. 2023 Jan; 613(7945): 767–774. Published online 2022 Nov 30. doi: 10.1038/s41586-022-05588-y
PMCID:
PMC10328120
AbstractArticlePDF–1.7M
12.
Morphine pharmacokinetics and opioid transporter expression at the blood-retina barrier of male and female mice
Casey-Tyler Berezin, Nikolas Bergum, Glenda M. Torres Lopez, Jozsef Vigh
Front Pharmacol. 2023; 14: 1206104. Published online 2023 Jun 14. doi: 10.3389/fphar.2023.1206104
PMCID:
PMC10301758
AbstractArticlePDF–4.0M
13.
Hyperactivity in Mice Induced by Opioid Agonists with Partial Intrinsic Efficacy and Biased Agonism Administered Alone and in Combination with Morphine
Agnes Acevedo-Canabal, Travis W. Grim, Cullen L. Schmid, Nina McFague, Edward L. Stahl, Nicole M. Kennedy, Thomas D. Bannister, Laura M. Bohn
Biomolecules. 2023 Jun; 13(6): 935. Published online 2023 Jun 2. doi: 10.3390/biom13060935
PMCID:
PMC10295947
AbstractArticlePDF–896K
14.
Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking
Nycole Maza, Dandan Wang, Cody Kowalski, Hannah M. Stoveken, Maria Dao, Omar K. Sial, Andrew C. Giles, Brock Grill, Kirill A. Martemyanov
Nat Neurosci. Author manuscript; available in PMC 2023 Jun 27.
Published in final edited form as: Nat Neurosci. 2022 Sep; 25(9): 1179–1190. Published online 2022 Aug 18. doi: 10.1038/s41593-022-01135-0
PMCID:
PMC10294603
AbstractArticlePDF–6.4M
15.
Loss of Astrocytic µ Opioid Receptors Exacerbates Aversion Associated with Morphine Withdrawal in Mice: Role of Mitochondrial Respiration
Kateryna Murlanova, Yan Jouroukhin, Ksenia Novototskaya-Vlasova, Shovgi Huseynov, Olga Pletnikova, Michael J. Morales, Yun Guan, Atsushi Kamiya, Dwight E. Bergles, David M. Dietz, Mikhail V. Pletnikov
Cells. 2023 May; 12(10): 1412. Published online 2023 May 17. doi: 10.3390/cells12101412
PMCID:
PMC10216734
AbstractArticlePDF–4.9M
16.
Characterization and mu opioid receptor sensitivity of neuropeptide Y interneurons in the mouse nucleus accumbens
Cassandra L. Retzlaff, Patrick E. Rothwell
Neuropharmacology. Author manuscript; available in PMC 2023 Nov 1.
Published in final edited form as: Neuropharmacology. 2022 Nov 1; 218: 109212. Published online 2022 Aug 10. doi: 10.1016/j.neuropharm.2022.109212
PMCID:
PMC10116437
AbstractArticlePDF–1.2M
17.
Parabrachial tachykinin1-expressing neurons involved in state-dependent breathing control
Joseph W. Arthurs, Anna J. Bowen, Richard D. Palmiter, Nathan A. Baertsch
Nat Commun. 2023; 14: 963. Published online 2023 Feb 21. doi: 10.1038/s41467-023-36603-z
PMCID:
PMC9944916
AbstractArticlePDF–64M
18.
µ-Opioid Receptors Expressed by Intrinsically Photosensitive Retinal Ganglion Cells Contribute to Morphine-Induced Behavioral Sensitization
Nikolas Bergum, Casey-Tyler Berezin, Connie M. King, Jozsef Vigh
Int J Mol Sci. 2022 Dec; 23(24): 15870. Published online 2022 Dec 14. doi: 10.3390/ijms232415870
PMCID:
PMC9781919
AbstractArticlePDF–1.8M
19.
A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells
Juliet Mengaziol, Amelia D. Dunn, Gregory Salimando, Lisa Wooldridge, Jordi Crues-Muncunill, Darrell Eacret, Chongguang Chen, Kathryn Bland, Lee-Yuan Liu- Chen, Michelle E. Ehrlich, Gregory Corder, Julie A. Blendy
PLoS One. 2022; 17(12): e0270317. Published online 2022 Dec 19. doi: 10.1371/journal.pone.0270317
PMCID:
PMC9762562
AbstractArticlePDF–5.8M
20.
Molecular and anatomical characterization of parabrachial neurons and their axonal projections
Jordan L Pauli, Jane Y Chen, Marcus L Basiri, Sekun Park, Matthew E Carter, Elisenda Sanz, G Stanley McKnight, Garret D Stuber, Richard D Palmiter
eLife. 2022; 11: e81868. Published online 2022 Nov 1. doi: 10.7554/eLife.81868
PMCID:
PMC9668336
AbstractArticlePDF–6.0M

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