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Select item 107165821.

Enhanced Akt3 kinase activity reduces atherosclerosis in hyperlipidemic mice in a gender-dependent manner

Lifang Zhang, Jessica Altemus, Liang Ding, Olga Cherepanova, Tatiana V. Byzova, Eugene A. Podrez

J Biol Chem. 2023 Dec; 299(12): 105425. Published online 2023 Nov 4. doi: 10.1016/j.jbc.2023.105425

PMCID:: PMC10716582

Abstract Article PDF–2.3M

Select item 103803162.

miR-29a-3p Regulates Autophagy by Targeting Akt3-Mediated mTOR in SiO₂-Induced Lung Fibrosis

Peiyuan Li, Xiaohui Hao, Jiaxin Liu, Qinxin Zhang, Zixuan Liang, Xinran Li, Heliang Liu

Int J Mol Sci. 2023 Jul; 24(14): 11440. Published online 2023 Jul 14. doi: 10.3390/ijms241411440

PMCID:: PMC10380316

Abstract Article PDF–10M

Select item 94407563.

TWIST1 interacts with β/δ-catenins during neural tube development and regulates fate transition in cranial neural crest cells

Jessica W. Bertol, Shelby Johnston, Rabia Ahmed, Victoria K. Xie, Kelsea M. Hubka, Lissette Cruz, Larissa Nitschke, Marta Stetsiv, Jeremy P. Goering, Paul Nistor, Sally Lowell, Hanne Hoskens, Peter Claes, Seth M. Weinberg, Irfan Saadi, Mary C. Farach-Carson, Walid D. Fakhouri

Development. 2022 Aug 1; 149(15): dev200068. Published online 2022 Aug 8. doi: 10.1242/dev.200068

PMCID:: PMC9440756

Abstract Article

Select item 86213374.

The Effects of Flavonoid Apigenin on Male Reproductive Health: Inhibition of Spermatogonial Proliferation through Downregulation of Prmt7/Akt3 Pathway

Bingyuan Wang, Mingrui Zhang, Jiankang Guo, Zhiguo Liu, Rong Zhou, Fei Guo, Kui Li, Yulian Mu

Int J Mol Sci. 2021 Nov; 22(22): 12209. Published online 2021 Nov 11. doi: 10.3390/ijms222212209

PMCID:: PMC8621337

Abstract Article PDF–1.9M

Select item 84828625.

Akt Regulates Sox10 Expression to Control Oligodendrocyte Differentiation via Phosphorylating FoxO1

He Wang, Mengjia Liu, Zhuoyang Ye, Cuihua Zhou, Huiru Bi, Long Wang, Chen Zhang, Hui Fu, Ying Shen, Jian-Jun Yang, Yimin Hu, Guiquan Chen

J Neurosci. 2021 Sep 29; 41(39): 8163–8180. doi: 10.1523/JNEUROSCI.2432-20.2021

PMCID:: PMC8482862

Abstract Article PDF–10M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82235037.

Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT’s Role in Complex Brain Disorders and Neurological Disease

Josien Levenga, Helen Wong, Ryan Milstead, Lauren LaPlante, Charles A Hoeffer

Cereb Cortex Commun. 2021; 2(2): tgab036. Published online 2021 May 28. doi: 10.1093/texcom/tgab036

PMCID:: PMC8223503

Abstract Article PDF–3.0M

Select item 80988148.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622

PMCID:: PMC8098814

Abstract Article PDF–7.7M

Select item 79387709.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 784655710.

The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization

Andres Ramirez-Martinez, Yichi Zhang, Kenian Chen, Jiwoong Kim, Bercin K. Cenik, John R. McAnally, Chunyu Cai, John M. Shelton, Jian Huang, Ana Brennan, Bret M. Evers, Pradeep P. A. Mammen, Lin Xu, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson

Nat Commun. 2021; 12: 690. Published online 2021 Jan 29. doi: 10.1038/s41467-021-20987-x

PMCID:: PMC7846557

Abstract Article PDF–2.9M

Select item 778766411.

Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders

Helen Wong, Josien Levenga, Lauren LaPlante, Bailey Keller, Andrew Cooper-Sansone, Curtis Borski, Ryan Milstead, Marissa Ehringer, Charles Hoeffer

eLife. 2020; 9: e56630. Published online 2020 Dec 16. doi: 10.7554/eLife.56630

PMCID:: PMC7787664

Abstract Article PDF–5.4M

Select item 768234812.

Akt3 induces oxidative stress and DNA damage by activating the NADPH oxidase via phosphorylation of p47^phox

Christos Polytarchou, Maria Hatziapostolou, Tung On Yau, Niki Christodoulou, Philip W. Hinds, Filippos Kottakis, Ioannis Sanidas, Philip N. Tsichlis

Proc Natl Acad Sci U S A. 2020 Nov 17; 117(46): 28806–28815. Published online 2020 Nov 2. doi: 10.1073/pnas.2017830117

PMCID:: PMC7682348

Abstract Article PDF–1.6M

Select item 759151413.

Akt isoform-specific effects on thyroid cancer development and progression in a murine thyroid cancer model

Motoyasu Saji, Caroline S. Kim, Chaojie Wang, Xiaoli Zhang, Tilak Khanal, Kevin Coombes, Krista La Perle, Sheue-Yann Cheng, Philip N. Tsichlis, Matthew D. Ringel

Sci Rep. 2020; 10: 18316. Published online 2020 Oct 27. doi: 10.1038/s41598-020-75529-0

PMCID:: PMC7591514

Abstract Article PDF–2.4M

Select item 756562214.

Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency

Jing Zhao, Liqian Zhu, Nishani Wijesekera, Clinton Jones

J Virol. 2020 Nov; 94(21): e00901-20. Prepublished online 2020 Aug 12. Published online 2020 Oct 14. doi: 10.1128/JVI.00901-20

PMCID:: PMC7565622

Abstract Article PDF–1.4M

Select item 741243015.

Circ‐AKT3 inhibits the accumulation of extracellular matrix of mesangial cells in diabetic nephropathy via modulating miR‐296‐3p/E‐cadherin signals

Bo Tang, Weiliang Li, Ting‐Ting Ji, Xiao‐Ying Li, Xiaolei Qu, Linhong Feng, Shoujun Bai

J Cell Mol Med. 2020 Aug; 24(15): 8779–8788. Published online 2020 Jun 28. doi: 10.1111/jcmm.15513

PMCID:: PMC7412430

Abstract Article PDF–1.6M

Select item 720248516.

AKT3 deficiency in M2 macrophages impairs cutaneous wound healing by disrupting tissue remodeling

Song Gu, Hanhao Dai, Xilian Zhao, Chang Gui, Jianchao Gui

Aging (Albany NY) 2020 Apr 30; 12(8): 6928–6946. Published online 2020 Apr 14. doi: 10.18632/aging.103051

PMCID:: PMC7202485

Abstract Article PDF–2.9M

Select item 718309717.

Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

Hayley I. Muendlein, Joseph Sarhan, Beiyun C. Liu, Wilson M. Connolly, Stephen A. Schworer, Irina Smirnova, Amy Y. Tang, Vladimir Ilyukha, Jodie Pietruska, Soroush Tahmasebi, Nahum Sonenberg, Alexei Degterev, Alexander Poltorak

Cell Rep. Author manuscript; available in PMC 2020 Apr 25.

Published in final edited form as: Cell Rep. 2020 Jan 21; 30(3): 699–713.e4. doi: 10.1016/j.celrep.2019.12.073

PMCID:: PMC7183097

Abstract Article PDF–2.7M

Select item 698963818.

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis

C. Martinez Calejman, S. Trefely, S. W. Entwisle, A. Luciano, S. M. Jung, W. Hsiao, A. Torres, C. M. Hung, H. Li, N. W. Snyder, J. Villén, K. E. Wellen, D. A. Guertin

Nat Commun. 2020; 11: 575. Published online 2020 Jan 29. doi: 10.1038/s41467-020-14430-w

Correction in:: Nat Commun. 2020; 11: 4585.

PMCID:: PMC6989638

Abstract Article PDF–3.8M

Select item 687822319.

The AKT isoforms 1 and 2 drive B cell fate decisions during the germinal center response

Zilu Zhu, Ashima Shukla, Parham Ramezani-Rad, John R Apgar, Robert C Rickert

Life Sci Alliance. 2019 Dec; 2(6): e201900506. Published online 2019 Nov 25. doi: 10.26508/lsa.201900506

PMCID:: PMC6878223

Abstract Article PDF–4.3M

Select item 680251320.

SIAH1 ubiquitin ligase mediates ubiquitination and degradation of Akt3 in neural development

Hyo Rim Ko, Eun-Ju Jin, Sang Bae Lee, Chung Kwon Kim, Taegwan Yun, Sung-Woo Cho, Kye Won Park, Jee-Yin Ahn

J Biol Chem. 2019 Oct 18; 294(42): 15435–15445. Published online 2019 Aug 30. doi: 10.1074/jbc.RA119.009618

PMCID:: PMC6802513

Abstract Article PDF–2.9M

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