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Select item 110670341.

Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC

Qing He, Feng Wang, Michael E. O’Donnell, Huilin Li

Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2319727121. Published online 2024 Apr 26. doi: 10.1073/pnas.2319727121

PMCID:: PMC11067034

Abstract Article PDF–17M

Select item 110259942.

A80G polymorphism of reduced folate carrier 1 (RFC1) and C776G polymorphism of transcobalamin 2 (TC2) genes in Down's syndrome etiology

Joice Matos Biselli, Daniela Brumati, Vivian Fernanda Frigeri, Bruna Lancia Zampieri, Eny Maria Goloni-Bertollo, Érika Cristina Pavarino-Bertelli

Sao Paulo Med J. 2008; 126(6): 329–332. Published online 2008 Nov 6. doi: 10.1590/S1516-31802008000600007

PMCID:: PMC11025994

Abstract Article PDF–153K

Select item 110081353.

Serum Folic Acid and RFC A80G Polymorphism in Alzheimer’s Disease and Vascular Dementia

Nasim Mansoori, Manjari Tripathi, Rizwan Alam, Kalpana Luthra, Sumit Sharma, Ramakrishnan Lakshmy, Mani Kalaivani, Asok K. Mukhopadhyay

Am J Alzheimers Dis Other Demen. 2014 Feb; 29(1): 38–44. Published online 2014 Feb 19. doi: 10.1177/1533317513505131

PMCID:: PMC11008135

Abstract Article PDF–156K

Select item 109902774.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 103378545.

LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex

Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yoshifumi Kawamura, Naoki Goshima, Nobuyoshi Akimitsu, Tetsu Akiyama

PNAS Nexus. 2023 Jul; 2(7): pgad220. Published online 2023 Jul 4. doi: 10.1093/pnasnexus/pgad220

PMCID:: PMC10337854

Abstract Article PDF–851K

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 98225217.

Methotrexate recognition by the human reduced folate carrier SLC19A1

Nicholas J. Wright, Justin G. Fedor, Han Zhang, Pyeonghwa Jeong, Yang Suo, Jiho Yoo, Jiyong Hong, Wonpil Im, Seok-Yong Lee

Nature. Author manuscript; available in PMC 2023 Jan 6.

Published in final edited form as: Nature. 2022 Sep; 609(7929): 1056–1062. Published online 2022 Sep 7. doi: 10.1038/s41586-022-05168-0

PMCID:: PMC9822521

Abstract Article PDF–5.3M

Select item 97947688.

Molecular mechanism of substrate recognition by folate transporter SLC19A1

Yu Dang, Dong Zhou, Xiaojuan Du, Hongtu Zhao, Chia-Hsueh Lee, Jing Yang, Yijie Wang, Changdong Qin, Zhenxi Guo, Zhe Zhang

Cell Discov. 2022; 8: 141. Published online 2022 Dec 28. doi: 10.1038/s41421-022-00508-w

PMCID:: PMC9794768

Abstract Article PDF–2.2M

Select item 94339389.

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan

EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698

PMCID:: PMC9433938

Abstract Article PDF–9.3M

Select item 935801910.

Hypoxia–Immune-Related Gene SLC19A1 Serves as a Potential Biomarker for Prognosis in Multiple Myeloma

Wenjin Li, Peng Yuan, Weiqin Liu, Lichan Xiao, Chun Xu, Qiuyu Mo, Shujuan Xu, Yuchan He, Duanfeng Jiang, Xiaotao Wang

Front Immunol. 2022; 13: 843369. Published online 2022 Jul 25. doi: 10.3389/fimmu.2022.843369

PMCID:: PMC9358019

Abstract Article PDF–9.5M

Select item 917141111.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 911973612.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 855290713.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 851385314.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 810379216.

The Roles of Reduced Folate Carrier-1 (RFC1) A80G (rs1051266) Polymorphism in Congenital Heart Disease: A Meta-Analysis

Kang Yi, Yu-Hu Ma, Wei Wang, Xin Zhang, Jie Gao, Shao-E He, Xiao-Min Xu, Meng Ji, Wen-Fen Guo, Tao You

Med Sci Monit. 2021; 27: e929911-1–e929911-12. Prepublished online 2021 Feb 21. Published online 2021 May 3. doi: 10.12659/MSM.929911

PMCID:: PMC8103792

Abstract Article PDF–812K

Select item 808868117.

The transcriptome profile of human trisomy 21 blood cells

Francesca Antonaros, Rossella Zenatelli, Giulia Guerri, Matteo Bertelli, Chiara Locatelli, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri, Giuseppe Ramacieri, Guido Cocchi, Pierluigi Strippoli, Maria Caracausi, Allison Piovesan

Hum Genomics. 2021; 15: 25. Published online 2021 May 1. doi: 10.1186/s40246-021-00325-4

PMCID:: PMC8088681

Abstract Article PDF–799K

Select item 797354518.

Folate transporter dynamics and therapy with classic and tumor-targeted antifolates

Carrie O’Connor, Adrianne Wallace-Povirk, Changwen Ning, Josephine Frühauf, Nian Tong, Aleem Gangjee, Larry H. Matherly, Zhanjun Hou

Sci Rep. 2021; 11: 6389. Published online 2021 Mar 18. doi: 10.1038/s41598-021-85818-x

PMCID:: PMC7973545

Abstract Article PDF–2.1M

Select item 734919619.

3’-UTR Polymorphisms of Vitamin B-Related Genes Are Associated with Osteoporosis and Osteoporotic Vertebral Compression Fractures (OVCFs) in Postmenopausal Women

Tae-Keun Ahn, Jung Oh Kim, Hui Jeong An, Han Sung Park, Un Yong Choi, Seil Sohn, Kyoung-Tae Kim, Nam Keun Kim, In-Bo Han

Genes (Basel) 2020 Jun; 11(6): 612. Published online 2020 Jun 2. doi: 10.3390/genes11060612

PMCID:: PMC7349196

Abstract Article PDF–1.9M

Select item 733001220.

A homozygous deletion in the SLC19A1 gene as a cause of folate-dependent recurrent megaloblastic anemia

Michael Svaton, Karolina Skvarova Kramarzova, Veronika Kanderova, Andrea Mancikova, Petr Smisek, Pavel Jesina, Jakub Krijt, Blanka Stiburkova, Robert Dobrovolny, Jitka Sokolova, Violeta Bakardjieva-Mihaylova, Elena Vodickova, Marketa Rackova, Jan Stuchly, Tomas Kalina, Jan Stary, Jan Trka, Eva Fronkova, Viktor Kozich

Blood. 2020 Jun 25; 135(26): 2427–2431. Prepublished online 2020 Apr 10. doi: 10.1182/blood.2019003178

PMCID:: PMC7330012

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