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Items: 1 to 20 of 208

1.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
2.
SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner
Anke Geng, Jiahui Sun, Huanyin Tang, Yang Yu, Xiyue Wang, Jingyuan Zhang, Xiaona Wang, Xiaoxiang Sun, Xiaofang Zhou, Neng Gao, Rong Tan, Zhu Xu, Ying Jiang, Zhiyong Mao
Nucleic Acids Res. 2024 May 22; 52(9): 5107–5120. Published online 2024 Mar 30. doi: 10.1093/nar/gkae190
PMCID:
PMC11109957
AbstractArticlePDF–2.3M
3.
沉默信息调节因子2在胆管癌中的表达及其对可切除胆管癌患者预后的预测价值
王 威, 季 文斌, 吕 振宇, 孙 万亮, 邵 玉, 刘 静, 杨 燕
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2024 Feb 25; 53(1): 98–107. Chinese. Published online 2023 Dec 5. doi: 10.3724/zdxbyxb-2023-0413
PMCID:
PMC10945490
AbstractArticlePDF–5.8M
4.
Decoding the multifaceted interventions between human sirtuin 2 and dynamic hepatitis B viral proteins to confirm their roles in HBV replication
Zahra Zahid Piracha, Umar Saeed, Irfan Ellahi Piracha, Seneen Noor, Elyeen Noor
Front Cell Infect Microbiol. 2023; 13: 1234903. Published online 2024 Jan 4. doi: 10.3389/fcimb.2023.1234903
PMCID:
PMC10794644
AbstractArticlePDF–787K
5.
FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation
Kai Chen, Yue Wang, Xingna Dai, Jingjing Luo, Shangshang Hu, Zhihui Zhou, Jinglong Shi, Xueshan Pan, Tong Cao, Jun Xia, Yuyun Li, Zhiwei Wang, Jia Ma
Cell Death Dis. 2024 Jan; 15(1): 37. Published online 2024 Jan 12. doi: 10.1038/s41419-024-06425-y
PMCID:
PMC10786907
AbstractArticlePDF–5.1M
6.
Sirtuin 2 promotes human cytomegalovirus replication by regulating cell cycle progression
Cora N. Betsinger, Joshua L. Justice, Matthew D. Tyl, Julia E. Edgar, Hanna G. Budayeva, Yaa F. Abu, Ileana M. Cristea
mSystems. 2023 Nov-Dec; 8(6): e00510-23. Published online 2023 Nov 2. doi: 10.1128/msystems.00510-23
PMCID:
PMC10734535
AbstractArticlePDF–4.5M
7.
Effects of Dimerization on the Deacylase Activities of Human SIRT2
Jie Yang, Nathan I. Nicely, Brian P. Weiser
Biochemistry. 2023 Dec 5; 62(23): 3383–3395. Published online 2023 Nov 15. doi: 10.1021/acs.biochem.3c00381
PMCID:
PMC10702427
AbstractArticlePDF–9.2M
8.
Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis
Qingsong Zhao, Nan Xia, Jinmei Xu, Yingnan Wang, Luwen Feng, Dihan Su, Zhifeng Cheng
J Innate Immun. 2023 Jan-Dec; 15(1): 614–628. Published online 2023 Jun 29. doi: 10.1159/000530966
PMCID:
PMC10601665
AbstractArticlePDF–1.8M
9.
SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells
Shu Yang, Guangyan Yang, Xinyu Wang, Jiaqing Xiang, Lin Kang, Zhen Liang
Cell Death Dis. 2023 Sep; 14(9): 646. Published online 2023 Sep 30. doi: 10.1038/s41419-023-06169-1
PMCID:
PMC10542381
AbstractArticlePDF–21M
10.
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
PamelaSara E Head, Priya Kapoor-Vazirani, Ganji P Nagaraju, Hui Zhang, Sandip K Rath, Nho C Luong, Ramona Haji-Seyed-Javadi, Fatmata Sesay, Shi-Ya Wang, Duc M Duong, Waaqo Daddacha, Elizabeth V Minten, Boying Song, Diana Danelia, Xu Liu, Shuyi Li, Eric A Ortlund, Nicholas T Seyfried, David M Smalley, Ya Wang, Xingming Deng, William S Dynan, Bassel El-Rayes, Anthony J Davis, David S Yu
Nucleic Acids Res. 2023 Aug 25; 51(15): 7972–7987. Published online 2023 Jul 3. doi: 10.1093/nar/gkad549
Correction in:
Nucleic Acids Res. 2023 Sep 22; 51(17): 9507.
PMCID:
PMC10450170
AbstractArticlePDF–2.2M
11.
SIRT2 regulates extracellular vesicle-mediated liver–bone communication
Longshuai Lin, Zengya Guo, Enjun He, Xidai Long, Difei Wang, Yingting Zhang, Weihong Guo, Qian Wei, Wei He, Wanying Wu, Jingchi Li, Lulu Wo, Dengli Hong, Junke Zheng, Ming He, Qinghua Zhao
Nat Metab. 2023; 5(5): 821–841. Published online 2023 May 15. doi: 10.1038/s42255-023-00803-0
PMCID:
PMC10229428
AbstractArticlePDF–21M
12.
SIRT2 plays complex roles in neuroinflammation neuroimmunology-associated disorders
Wenmei Lu, Haonan Ji, Danhong Wu
Front Immunol. 2023; 14: 1174180. Published online 2023 May 5. doi: 10.3389/fimmu.2023.1174180
PMCID:
PMC10196137
AbstractArticlePDF–2.4M
13.
Frequency of the rs2015 (T>G) and rs2241703 (G>A) polymorphisms in the miRNA-SIRT2 gene in type 2 diabetes mellitus in Saudi Arabia
Nahla A. Alshaikh, Siddig I. Abdelwahab, Mahmoud M. Habibullah, Ahmed A. Jerah, Mohammed A. Bakri, Yahia A. Kaabi
Saudi Med J. 2023 Apr; 44(4): 363–367. doi: 10.15537/smj.2023.44.4.20220863
PMCID:
PMC10153611
AbstractArticlePDF–410K
14.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
15.
Promotion of Lung Cancer Metastasis by SIRT2‐Mediated Extracellular Protein Deacetylation
Meng Wu, Jian‐Bin Zhang, Yi‐Wei Xiong, Yong‐Xu Zhao, Meng‐Ge Zheng, Xia‐Li Huang, Fang Huang, Xing‐Xing Wu, Xue Li, Wei‐Jiao Fan, Lin Hu, Yuan‐Yuan Zeng, Xia‐Ju Cheng, Ji‐Cheng Yue, Juan‐Juan Du, Nan‐Nan Chen, Wen‐Xiang Wei, Qing‐Hua Yao, Xiao‐mei Lu, Chao Huang, Jiong Deng, Zhi‐Jie Chang, He‐Bin Liu, Ting C. Zhao, Y. Eugene Chinn
Adv Sci (Weinh) 2023 Jan; 10(3): 2205462. Published online 2022 Dec 1. doi: 10.1002/advs.202205462
PMCID:
PMC9875677
AbstractArticlePDF–7.4M
16.
SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail
Yonghao Tian, Ruijuan Liu, Xiaoyan Hou, Zhixiao Gao, Xinyu Liu, Weifang Zhang
Cell Death Dis. 2022 Nov; 13(11): 935. Published online 2022 Nov 7. doi: 10.1038/s41419-022-05388-2
PMCID:
PMC9640536
AbstractArticlePDF–4.1M
17.
Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression
Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng
Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651
PMCID:
PMC9629121
AbstractArticlePDF–8.1M
18.
Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1
Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin
J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379
PMCID:
PMC9513271
AbstractArticlePDF–2.7M
19.
Sirt2 promotes white matter oligodendrogenesis during development and in models of neonatal hypoxia
Beata Jablonska, Katrina L. Adams, Panagiotis Kratimenos, Zhen Li, Emma Strickland, Tarik F. Haydar, Katharina Kusch, Klaus-Armin Nave, Vittorio Gallo
Nat Commun. 2022; 13: 4771. Published online 2022 Aug 15. doi: 10.1038/s41467-022-32462-2
PMCID:
PMC9378658
AbstractArticlePDF–12M
20.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M

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