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Items: 1 to 20 of 53

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Lysyl oxidase‐like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3
Yi‐Jie Lu, Yi‐Ting Deng, Hui‐Hsin Ko, Hsin‐Hui Peng, Hsiang‐Chieh Lee, Mark Yen‐Ping Kuo, Shih‐Jung Cheng
Cancer Sci. 2023 Oct; 114(10): 3957–3971. Published online 2023 Jul 26. doi: 10.1111/cas.15912
PMCID:
PMC10551584
AbstractArticlePDF–48M
3.
SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology
Kristine E. Zengeler, Daniel A. Shapiro, Katherine R. Bruch, Catherine R. Lammert, Hannah Ennerfelt, John R. Lukens
Brain Behav Immun. Author manuscript; available in PMC 2023 Jun 26.
Published in final edited form as: Brain Behav Immun. 2023 Feb; 108: 80–97. Published online 2022 Nov 4. doi: 10.1016/j.bbi.2022.10.024
PMCID:
PMC10291741
AbstractArticlePDF–2.7M
4.
Adar1 deletion causes degeneration of the exocrine pancreas via Mavs-dependent interferon signaling
Dhwani N. Rupani, Fredrik I. Thege, Vidhi Chandra, Hajar Rajaei, Robert W. Cowan, Sonja M. Wörmann, Olivereen Le Roux, Prerna Malaney, Sara L. Manning, Jack Hashem, Jennifer Bailey-Lundberg, Andrew D. Rhim, Florencia McAllister
Development. 2023 Jan 15; 150(2): dev201097. Published online 2023 Jan 16. doi: 10.1242/dev.201097
PMCID:
PMC10110501
AbstractArticle
5.
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) accelerates osteoclast formation by regulating signal transducer and activator of transcription 3 (STAT3) signalling
Yuanliang Xue, Chuanliang Zhao, Tao Liu
Bioengineered. 2022; 13(2): 2285–2295. Published online 2022 Jan 16. doi: 10.1080/21655979.2021.2024333
PMCID:
PMC8973581
AbstractArticlePDF–2.3M
6.
PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS‐STING‐Mediated Interferon Response
Xinwei Geng, Chao Zhang, Miao Li, Jiaqi Wang, Fang Ji, Hanrong Feng, Meichun Xing, Fei Li, Lingling Zhang, Wen Li, Zhihua Chen, Ian D. Hickson, Huahao Shen, Songmin Ying
Adv Sci (Weinh) 2022 Mar; 9(7): 2103837. Published online 2022 Jan 17. doi: 10.1002/advs.202103837
PMCID:
PMC8895048
AbstractArticlePDF–3.9M
7.
Genome Instability Independent of Type I Interferon Signaling Drives Neuropathology Caused by Impaired Ribonucleotide Excision Repair
Aditi, Susanna M. Downing, Patrick A. Schreiner, Young Don Kwak, Yang Li, Timothy I. Shaw, Helen R. Russell, Peter J. McKinnon
Neuron. Author manuscript; available in PMC 2022 Dec 15.
Published in final edited form as: Neuron. 2021 Dec 15; 109(24): 3962–3979.e6. Published online 2021 Oct 15. doi: 10.1016/j.neuron.2021.09.040
PMCID:
PMC8686690
AbstractArticlePDF–4.1M
8.
RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain
Jung In Kim, Taisuke Nakahama, Ryuichiro Yamasaki, Pedro Henrique Costa Cruz, Tuangtong Vongpipatana, Maal Inoue, Nao Kanou, Yanfang Xing, Hiroyuki Todo, Toshiharu Shibuya, Yuki Kato, Yukio Kawahara
PLoS Genet. 2021 May; 17(5): e1009516. Published online 2021 May 13. doi: 10.1371/journal.pgen.1009516
PMCID:
PMC8118328
AbstractArticlePDF–4.3M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
Mouse Ifit1b is a cap1-RNA–binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c
Harriet V. Mears, Trevor R. Sweeney
J Biol Chem. 2020 Dec 18; 295(51): 17781–17801. Published online 2020 Oct 19. doi: 10.1074/jbc.RA120.014695
PMCID:
PMC7762956
AbstractArticlePDF–4.9M
11.
Development of interferon-stimulated gene expression from embryogenesis through adulthood, with and without constitutive MDA5 pathway activation
Laura Bankers, Caitlin Miller, Guoqi Liu, Chommanart Thongkittidilok, James Morrison, Eric M. Poeschla
J Immunol. Author manuscript; available in PMC 2021 May 15.
Published in final edited form as: J Immunol. 2020 May 15; 204(10): 2791–2807. Published online 2020 Apr 10. doi: 10.4049/jimmunol.1901421
PMCID:
PMC7326337
AbstractArticlePDF–1.1M
12.
ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development
Nadjet Gacem, Anthula Kavo, Lisa Zerad, Laurence Richard, Stephane Mathis, Raj P. Kapur, Melanie Parisot, Jeanne Amiel, Sylvie Dufour, Pierre de la Grange, Veronique Pingault, Jean Michel Vallat, Nadege Bondurand
Nat Commun. 2020; 11: 198. Published online 2020 Jan 10. doi: 10.1038/s41467-019-14090-5
PMCID:
PMC6954203
AbstractArticlePDF–5.1M
13.
Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation
Timothy A. Norman, Jr., Adam C. Gower, Felicia Chen, Alan Fine
PLoS One. 2019; 14(5): e0216795. Published online 2019 May 13. doi: 10.1371/journal.pone.0216795
PMCID:
PMC6513083
AbstractArticlePDF–3.8M
14.
IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages
Sinu P. John, Jing Sun, Rebecca J. Carlson, Binh Cao, Clinton J. Bradfield, Jian Song, Margery Smelkinson, Iain D.C. Fraser
Cell Rep. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: Cell Rep. 2018 Oct 2; 25(1): 95–106.e6. doi: 10.1016/j.celrep.2018.09.002
PMCID:
PMC6492923
AbstractArticlePDF–1.1M
15.
Ifit1 Protects Against Lipopolysaccharide and D-galactosamine–Induced Fatal Hepatitis by Inhibiting Activation of the JNK Pathway
Antao Chang, Yanan Chen, Wenzhi Shen, Ruifang Gao, Wei Zhou, Shuang Yang, Yanhua Liu, Yunping Luo, Tsung-Hsien Chuang, Peiqing Sun, Chenghu Liu, Rong Xiang
J Infect Dis. 2015 Nov; 212(9): 1509–1520. Published online 2015 Oct 9. doi: 10.1093/infdis/jiv221
PMCID:
PMC6373839
AbstractArticle
16.
Two RNase H2 Mutants with Differential rNMP Processing Activity Reveal a Threshold of Ribonucleotide Tolerance for Embryonic Development
Ryo Uehara, Susana M. Cerritelli, Naushaba Hasin, Kiran Sakhuja, Mariya London, Jaime Iranzo, Hyongi Chon, Alexander Grinberg, Robert J. Crouch
Cell Rep. Author manuscript; available in PMC 2018 Dec 28.
Published in final edited form as: Cell Rep. 2018 Oct 30; 25(5): 1135–1145.e5. doi: 10.1016/j.celrep.2018.10.019
PMCID:
PMC6309994
AbstractArticlePDF–933K
17.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
18.
The Interferon-Induced Exonuclease ISG20 Exerts Antiviral Activity through Upregulation of Type I Interferon Response Proteins
Christopher M. Weiss, Derek W. Trobaugh, Chengqun Sun, Tiffany M. Lucas, Michael S. Diamond, Kate D. Ryman, William B. Klimstra
mSphere. 2018 Sep-Oct; 3(5): e00209-18. Published online 2018 Sep 19. doi: 10.1128/mSphere.00209-18
PMCID:
PMC6147134
AbstractArticlePDF–3.1M
19.
Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis
Jacki E. Heraud-Farlow, Alistair M. Chalk, Sandra E. Linder, Qin Li, Scott Taylor, Joshua M. White, Lokman Pang, Brian J. Liddicoat, Ankita Gupte, Jin Billy Li, Carl R. Walkley
Genome Biol. 2017; 18: 166. Published online 2017 Sep 5. doi: 10.1186/s13059-017-1301-4
PMCID:
PMC5585977
AbstractArticlePDF–2.3M
20.
Ifit2 Is a Restriction Factor in Rabies Virus Pathogenicity
Benjamin M. Davis, Volker Fensterl, Tessa M. Lawrence, Andrew W. Hudacek, Ganes C. Sen, Matthias J. Schnell
J Virol. 2017 Sep 1; 91(17): e00889-17. Prepublished online 2017 Jun 21. Published online 2017 Aug 10. doi: 10.1128/JVI.00889-17
PMCID:
PMC5553164
AbstractArticlePDF–1.2M

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