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Select item 111892971.

Tead4 and Tfap2c generate bipotency and a bistable switch in totipotent embryos to promote robust lineage diversification

Meng Zhu, Maciej Meglicki, Adiyant Lamba, Peizhe Wang, Christophe Royer, Karen Turner, Muhammad Abdullah Jauhar, Celine Jones, Tim Child, Kevin Coward, Jie Na, Magdalena Zernicka-Goetz

Nat Struct Mol Biol. 2024; 31(6): 964–976. Published online 2024 May 24. doi: 10.1038/s41594-024-01311-9

PMCID:: PMC11189297

Abstract Article PDF–6.5M

Select item 103567712.

Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution

Matthieu Dos Santos, Akansha M. Shah, Yichi Zhang, Svetlana Bezprozvannaya, Kenian Chen, Lin Xu, Weichun Lin, John R. McAnally, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson

Nat Commun. 2023; 14: 4333. Published online 2023 Jul 19. doi: 10.1038/s41467-023-40073-8

PMCID:: PMC10356771

Abstract Article PDF–4.9M

Select item 90358233.

Nutrient Transporter Gene Expression in the Early Conceptus—Implications From Two Mouse Models of Diabetic Pregnancy

Claudia Kappen, Claudia Kruger, Sydney Jones, J. Michael Salbaum

Front Cell Dev Biol. 2022; 10: 777844. Published online 2022 Apr 11. doi: 10.3389/fcell.2022.777844

PMCID:: PMC9035823

Abstract Article PDF–5.7M

Select item 82108854.

Developmental clock and mechanism of de novo polarization of the mouse embryo

Meng Zhu, Jake Cornwall-Scoones, Peizhe Wang, Charlotte E. Handford, Jie Na, Matt Thomson, Magdalena Zernicka-Goetz

Science. Author manuscript; available in PMC 2021 Jun 17.

Published in final edited form as: Science. 2020 Dec 11; 370(6522): eabd2703. doi: 10.1126/science.abd2703

PMCID:: PMC8210885

Abstract Article PDF–3.5M

Select item 79689255.

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam

eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873

PMCID:: PMC7968925

Abstract Article PDF–4.0M

Select item 77335326.

Loss of Anks6 leads to YAP deficiency and liver abnormalities

Merlin Airik, Markus Schüler, Blake McCourt, Anna-Carina Weiss, Nathan Herdman, Timo H Lüdtke, Eugen Widmeier, Donna B Stolz, Kari N Nejak-Bowen, Dean Yimlamai, Yijen L Wu, Andreas Kispert, Rannar Airik, Friedhelm Hildebrandt

Hum Mol Genet. 2020 Sep 15; 29(18): 3064–3080. Published online 2020 Sep 4. doi: 10.1093/hmg/ddaa197

PMCID:: PMC7733532

Abstract Article PDF–2.9M

Select item 69544487.

Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse

Qian-Qian Sha, Ye-Zhang Zhu, Sen Li, Yu Jiang, Lu Chen, Xiao-Hong Sun, Li Shen, Xiang-Hong Ou, Heng-Yu Fan

Nucleic Acids Res. 2020 Jan 24; 48(2): 879–894. Published online 2019 Nov 28. doi: 10.1093/nar/gkz1111

PMCID:: PMC6954448

Abstract Article PDF–5.5M

Select item 69367088.

Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease

Sumantra Chatterjee, Priyanka Nandakumar, Dallas R. Auer, Stacey B. Gabriel, Aravinda Chakravarti

Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52): 26697–26708. Published online 2019 Dec 9. doi: 10.1073/pnas.1908756116

PMCID:: PMC6936708

Abstract Article PDF–2.1M

Select item 67651269.

TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage

Tristan Frum, Jennifer L. Watts, Amy Ralston

Development. 2019 Sep 1; 146(17): dev179861. Published online 2019 Sep 6. doi: 10.1242/dev.179861

PMCID:: PMC6765126

Abstract Article

Select item 648615210.

Transitions in cell potency during early mouse development are driven by Notch

Sergio Menchero, Isabel Rollan, Antonio Lopez-Izquierdo, Maria Jose Andreu, Julio Sainz de Aja, Minjung Kang, Javier Adan, Rui Benedito, Teresa Rayon, Anna-Katerina Hadjantonakis, Miguel Manzanares

eLife. 2019; 8: e42930. Published online 2019 Apr 8. doi: 10.7554/eLife.42930

PMCID:: PMC6486152

Abstract Article PDF–4.4M

Select item 622210611.

The TEA domain family transcription factor TEAD4 represses murine adipogenesis by recruiting the cofactors VGLL4 and CtBP2 into a transcriptional complex

Wenxiang Zhang, Jinjin Xu, Jinhui Li, Tong Guo, Dan Jiang, Xue Feng, Xueyan Ma, Lingli He, Wenqing Wu, Mengxin Yin, Ling Ge, Zuoyun Wang, Margaret S. Ho, Yun Zhao, Zhaoliang Fei, Lei Zhang

J Biol Chem. 2018 Nov 2; 293(44): 17119–17134. Published online 2018 Sep 12. doi: 10.1074/jbc.RA118.003608

PMCID:: PMC6222106

Abstract Article PDF–4.3M

Select item 619847612.

Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription

Ram P. Kumar, Soma Ray, Pratik Home, Biswarup Saha, Bhaswati Bhattacharya, Heather M. Wilkins, Hemantkumar Chavan, Avishek Ganguly, Jessica Milano-Foster, Arindam Paul, Partha Krishnamurthy, Russell H. Swerdlow, Soumen Paul

Development. 2018 Oct 1; 145(19): dev162644. Published online 2018 Oct 1. doi: 10.1242/dev.162644

PMCID:: PMC6198476

Abstract Article

Select item 590871013.

A histone deacetylase 3–dependent pathway delimits peripheral myelin growth and functional regeneration

Xuelian He, Liguo Zhang, Luis F Queme, Xuezhao Liu, Andrew Lu, Ronald R Waclaw, Xinran Dong, Wenhao Zhou, Grahame Kidd, Sung-Ok Yoon, Andres Buonanno, Joshua B Rubin, Mei Xin, Klaus-Armin Nave, Bruce D Trapp, Michael P Jankowski, Q Richard Lu

Nat Med. Author manuscript; available in PMC 2018 Apr 19.

Published in final edited form as: Nat Med. 2018 Mar; 24(3): 338–351. Published online 2018 Feb 12. doi: 10.1038/nm.4483

PMCID:: PMC5908710

Abstract Article PDF–3.0M

Select item 585931814.

INDUCTION OF A TROPHOBLAST-LIKE PHENOTYPE BY HYDRALAZINE IN THE P19 EMBRYONIC CARCINOMA CELL LINE

Cliona M. O’Driscoll, Jonathan B. Coulter, Joseph P. Bressler

Biochim Biophys Acta. Author manuscript; available in PMC 2018 Mar 20.

Published in final edited form as: Biochim Biophys Acta. 2013 Mar; 1833(3): 460–467. Published online 2012 Nov 26. doi: 10.1016/j.bbamcr.2012.11.012

PMCID:: PMC5859318

Abstract Article PDF–1.1M

Select item 537018815.

Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

Eszter Posfai, Sophie Petropoulos, Flavia Regina Oliveira de Barros, John Paul Schell, Igor Jurisica, Rickard Sandberg, Fredrik Lanner, Janet Rossant

eLife. 2017; 6: e22906. Published online 2017 Feb 22. doi: 10.7554/eLife.22906

PMCID:: PMC5370188

Abstract Article PDF–5.6M

Select item 532302116.

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo

Shilpy Joshi, Guillaume Davidson, Stéphanie Le Gras, Shuichi Watanabe, Thomas Braun, Gabrielle Mengus, Irwin Davidson

PLoS Genet. 2017 Feb; 13(2): e1006600. Published online 2017 Feb 8. doi: 10.1371/journal.pgen.1006600

PMCID:: PMC5323021

Abstract Article PDF–5.1M

Select item 520104517.

Cooperative binding of AP-1 and TEAD4 modulates the balance between vascular smooth muscle and hemogenic cell fate

Nadine Obier, Pierre Cauchy, Salam A. Assi, Jane Gilmour, Michael Lie-A-Ling, Monika Lichtinger, Maarten Hoogenkamp, Laura Noailles, Peter N. Cockerill, Georges Lacaud, Valerie Kouskoff, Constanze Bonifer

Development. 2016 Dec 1; 143(23): 4324–4340. doi: 10.1242/dev.139857

PMCID:: PMC5201045

Abstract Article

Select item 502579018.

Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency

Alessandro Fiorenzano, Emilia Pascale, Cristina D'Aniello, Dario Acampora, Cecilia Bassalert, Francesco Russo, Gennaro Andolfi, Mauro Biffoni, Federica Francescangeli, Ann Zeuner, Claudia Angelini, Claire Chazaud, Eduardo J. Patriarca, Annalisa Fico, Gabriella Minchiotti

Nat Commun. 2016; 7: 12589. Published online 2016 Sep 2. doi: 10.1038/ncomms12589

PMCID:: PMC5025790

Abstract Article PDF–4.7M

Select item 478346919.

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse

Chao Yu, Shu-Yan Ji, Yu-Jiao Dang, Qian-Qian Sha, Yi-Feng Yuan, Jian-Jie Zhou, Li-Ying Yan, Jie Qiao, Fuchou Tang, Heng-Yu Fan

Cell Res. 2016 Mar; 26(3): 275–287. Published online 2016 Feb 23. doi: 10.1038/cr.2016.20

PMCID:: PMC4783469

Abstract Article PDF–9.2M

Select item 455249320.

Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages

Jens-Erik Dietrich, Laura Panavaite, Stefan Gunther, Sebastian Wennekamp, Anna C Groner, Anton Pigge, Stefanie Salvenmoser, Didier Trono, Lars Hufnagel, Takashi Hiiragi

EMBO Rep. 2015 Aug; 16(8): 1005–1021. Published online 2015 Jul 3. doi: 10.15252/embr.201540162