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Items: 1 to 20 of 37

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair
Richard O. Adeyemi, Nicholas A. Willis, Andrew E.H. Elia, Connor Clairmont, Shibo Li, Xiaohua Wu, Alan D. D’Andrea, Ralph Scully, Stephen J. Elledge
Mol Cell. Author manuscript; available in PMC 2022 Nov 4.
Published in final edited form as: Mol Cell. 2021 Nov 4; 81(21): 4440–4456.e7. Published online 2021 Sep 30. doi: 10.1016/j.molcel.2021.09.008
PMCID:
PMC8588999
AbstractArticlePDF–2.2M
3.
DNA polymerase zeta contributes to heterochromatin replication to prevent genome instability
Barbara Ben Yamin, Sana Ahmed‐Seghir, Junya Tomida, Emmanuelle Despras, Caroline Pouvelle, Andrey Yurchenko, Jordane Goulas, Raphael Corre, Quentin Delacour, Nathalie Droin, Philippe Dessen, Didier Goidin, Sabine S Lange, Sarita Bhetawal, Maria Teresa Mitjavila‐Garcia, Giuseppe Baldacci, Sergey Nikolaev, Jean Charles Cadoret, Richard D Wood, Patricia L Kannouche
EMBO J. 2021 Nov 2; 40(21): e104543. Published online 2021 Sep 17. doi: 10.15252/embj.2020104543
PMCID:
PMC8561639
AbstractArticlePDF–4.4M
4.
Disruption of DNA polymerase ζ engages an innate immune response
Sara K. Martin, Junya Tomida, Richard D. Wood
Cell Rep. Author manuscript; available in PMC 2021 Mar 24.
Published in final edited form as: Cell Rep. 2021 Feb 23; 34(8): 108775. doi: 10.1016/j.celrep.2021.108775
PMCID:
PMC7990024
AbstractArticlePDF–1.2M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
DNA polymerase ζ in DNA replication and repair
Sara K Martin, Richard D Wood
Nucleic Acids Res. 2019 Sep 19; 47(16): 8348–8361. Published online 2019 Aug 14. doi: 10.1093/nar/gkz705
PMCID:
PMC6895278
AbstractArticlePDF–3.1M
7.
DNA polymerase ζ deficiency causes impaired wound healing and stress-induced skin pigmentation
Sabine S Lange, Sarita Bhetawal, Shelley Reh, Katherine Leslie Powell, Donna F Kusewitt, Richard D Wood
Life Sci Alliance. 2018 Jun; 1(3): e201800048. Published online 2018 Jun 29. doi: 10.26508/lsa.201800048
PMCID:
PMC6055517
AbstractArticlePDF–5.1M
8.
DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure
Ying-Chih Lin, Nichole Owen, Irina G. Minko, Sabine S. Lange, Junya Tomida, Liang Li, Michael P. Stone, Richard D. Wood, Amanda K. McCullough, R. Stephen Lloyd
Proc Natl Acad Sci U S A. 2016 Nov 29; 113(48): 13774–13779. Published online 2016 Nov 14. doi: 10.1073/pnas.1609024113
Correction in:
Proc Natl Acad Sci U S A. 2017 Jan 17; 114(3): E437.
PMCID:
PMC5137696
AbstractArticlePDF–1.2M
9.
The Polymerase Activity of Mammalian DNA Pol ζ Is Specifically Required for Cell and Embryonic Viability
Sabine S. Lange, Junya Tomida, Karen S. Boulware, Sarita Bhetawal, Richard D. Wood
PLoS Genet. 2016 Jan; 12(1): e1005759. Published online 2016 Jan 4. doi: 10.1371/journal.pgen.1005759
PMCID:
PMC4699697
AbstractArticlePDF–2.3M
10.
De novo mutations in PLXND1 and REV3L cause Möbius syndrome
Laura Tomas-Roca, Anastasia Tsaalbi-Shtylik, Jacob G. Jansen, Manvendra K. Singh, Jonathan A. Epstein, Umut Altunoglu, Harriette Verzijl, Laura Soria, Ellen van Beusekom, Tony Roscioli, Zafar Iqbal, Christian Gilissen, Alexander Hoischen, Arjan P. M. de Brouwer, Corrie Erasmus, Dirk Schubert, Han Brunner, Antonio Pérez Aytés, Faustino Marin, Pilar Aroca, Hülya Kayserili, Arturo Carta, Niels de Wind, George W. Padberg, Hans van Bokhoven
Nat Commun. 2015; 6: 7199. Published online 2015 Jun 12. doi: 10.1038/ncomms8199
PMCID:
PMC4648025
AbstractArticlePDF–1.9M
11.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
12.
siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/− with susceptibility versus C57BL/6-Trp53+/− mice with resistance to mammary tumors
M Böhringer, K Obermeier, N Griner, D Waldraff, E Dickinson, K Eirich, D Schindler, M Hagen, D J Jerry, L Wiesmüller
Oncogene. 2013 Nov 28; 32(48): 5458–5470. Published online 2013 Feb 25. doi: 10.1038/onc.2013.38
PMCID:
PMC3898496
AbstractArticlePDF–1.6M
13.
The REV7 Subunit of DNA Polymerase ζ Is Essential for Primordial Germ Cell Maintenance in the Mouse
Naoki Watanabe, Shinji Mii, Naoya Asai, Masato Asai, Kaoru Niimi, Kaori Ushida, Takuya Kato, Atsushi Enomoto, Hideshi Ishii, Masahide Takahashi, Yoshiki Murakumo
J Biol Chem. 2013 Apr 12; 288(15): 10459–10471. Published online 2013 Mar 5. doi: 10.1074/jbc.M112.421966
PMCID:
PMC3624428
AbstractArticlePDF–3.4M
14.
Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses
Sabine S. Lange, Ella Bedford, Shelley Reh, John P. Wittschieben, Steve Carbajal, Donna F. Kusewitt, John DiGiovanni, Richard D. Wood
Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E687–E696. Published online 2013 Feb 5. doi: 10.1073/pnas.1217425110
PMCID:
PMC3581960
AbstractArticlePDF–3.1M
15.
Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis
Milica Enoiu, Josef Jiricny, Orlando D. Schärer
Nucleic Acids Res. 2012 Oct; 40(18): 8953–8964. Published online 2012 Jul 18. doi: 10.1093/nar/gks670
PMCID:
PMC3467066
AbstractArticlePDF–818K
16.
Structural Basis of Rev1-mediated Assembly of a Quaternary Vertebrate Translesion Polymerase Complex Consisting of Rev1, Heterodimeric Polymerase (Pol) ζ, and Pol κ
Jessica Wojtaszek, Chul-Jin Lee, Sanjay D'Souza, Brenda Minesinger, Hyungjin Kim, Alan D. D'Andrea, Graham C. Walker, Pei Zhou
J Biol Chem. 2012 Sep 28; 287(40): 33836–33846. Published online 2012 Aug 2. doi: 10.1074/jbc.M112.394841
PMCID:
PMC3460478
AbstractArticlePDF–2.3M
17.
DNA polymerase zeta is required for proliferation of normal mammalian cells
Sabine S. Lange, John P. Wittschieben, Richard D. Wood
Nucleic Acids Res. 2012 May; 40(10): 4473–4482. Published online 2012 Feb 7. doi: 10.1093/nar/gks054
PMCID:
PMC3378892
AbstractArticlePDF–3.5M
18.
DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions
Huseyin Saribasak, Robert W. Maul, Zheng Cao, William W. Yang, Dominik Schenten, Sven Kracker, Patricia J. Gearhart
J Exp Med. 2012 Jun 4; 209(6): 1075–1081. doi: 10.1084/jem.20112234
PMCID:
PMC3371727
AbstractArticlePDF–1.2M
19.
Altered immunoglobulin hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity
Janssen Daly, Katarzyna Bebenek, Danielle L. Watt, Kathleen Richter, Chuancang Jiang, Ming-Lang Zhao, Madhumita Ray, W. Glenn McGregor, Thomas A. Kunkel, Marilyn Diaz
J Immunol. Author manuscript; available in PMC 2013 Jun 1.
Published in final edited form as: J Immunol. 2012 Jun 1; 188(11): 5528–5537. Published online 2012 Apr 30. doi: 10.4049/jimmunol.1102629
PMCID:
PMC3358437
AbstractArticlePDF–1.2M
20.
The Vital Role of Polymerase ζ and REV1 in Mutagenic, but Not Correct, DNA Synthesis across Benzo[a]pyrene-dG and Recruitment of Polymerase ζ by REV1 to Replication-stalled Site
Keiji Hashimoto, Youngjin Cho, In-Young Yang, Jun-ichi Akagi, Eiji Ohashi, Satoshi Tateishi, Niels de Wind, Fumio Hanaoka, Haruo Ohmori, Masaaki Moriya
J Biol Chem. 2012 Mar 16; 287(12): 9613–9622. Published online 2012 Feb 2. doi: 10.1074/jbc.M111.331728
PMCID:
PMC3308759
AbstractArticlePDF–1.0M

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