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Select item 107538181.

Effects of secretin gene knockout on the diversity, composition, and function of gut microbiota in adult male mice

Fengwei Zhang, Zhengyi Tao, Congjia Chen, Billy Kwok Chong Chow

Front Cell Infect Microbiol. 2023; 13: 1257857. Published online 2023 Dec 13. doi: 10.3389/fcimb.2023.1257857

PMCID:: PMC10753818

Abstract Article PDF–4.3M

Select item 87822462.

Inhibition of secretin/secretin receptor axis ameliorates non-alcoholic fatty liver disease phenotypes

Lixian Chen, Nan Wu, Lindsey Kennedy, Heather Francis, Ludovica Ceci, Tianhao Zhou, Niharika Samala, Konstantina Kyritsi, Chaodong Wu, Amelia Sybenga, Burcin Ekser, Wasim Dar, Constance Atkins, Vik Meadows, Shannon Glaser, Gianfranco Alpini

Hepatology. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: Hepatology. 2021 Oct; 74(4): 1845–1863. Published online 2021 Jul 29. doi: 10.1002/hep.31871

PMCID:: PMC8782246

Abstract Article PDF–2.6M

Select item 79587143.

A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

Kristoffer L. Egerod, Maja S. Engelstoft, Kaare V. Grunddal, Mark K. Nøhr, Anna Secher, Ichiro Sakata, Jens Pedersen, Johanne A. Windeløv, Ernst-Martin Füchtbauer, Jørgen Olsen, Frank Sundler, Jan P. Christensen, Nils Wierup, Jesper V. Olsen, Jens J. Holst, Jeffrey M. Zigman, Steen S. Poulsen, Thue W. Schwartz

Endocrinology. 2012 Dec 1; 153(12): 5782–5795. Published online 2012 Dec 1. doi: 10.1210/en.2012-1595

PMCID:: PMC7958714

Abstract Article

Select item 67750674.

Loss of secretin results in systemic and pulmonary hypertension with cardiopulmonary pathologies in mice

Aung Moe Zaw, Revathi Sekar, Sarah O. K. Mak, Helen K. W. Law, Billy K. C. Chow

Sci Rep. 2019; 9: 14211. Published online 2019 Oct 2. doi: 10.1038/s41598-019-50634-x

PMCID:: PMC6775067

Abstract Article PDF–4.3M

Select item 67287665.

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

Julie Piccand, Constance Vagne, Florence Blot, Aline Meunier, Anthony Beucher, Perrine Strasser, Mari L. Lund, Sabitri Ghimire, Laure Nivlet, Céline Lapp, Natalia Petersen, Maja S. Engelstoft, Christelle Thibault-Carpentier, Céline Keime, Sara Jimenez Correa, Valérie Schreiber, Nacho Molina, Thue W. Schwartz, Adèle De Arcangelis, Gérard Gradwohl

Mol Metab. 2019 Nov; 29: 24–39. Published online 2019 Aug 13. doi: 10.1016/j.molmet.2019.08.007

PMCID:: PMC6728766

Abstract Article PDF–3.3M

Select item 62147146.

Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2^−/− mice by diminishing senescence of cholangiocytes

Tianhao Zhou, Nan Wu, Fanyin Meng, Julie Venter, Thao K Giang, Heather Francis, Konstantina Kyritsi, Chaodong Wu, Antonio Franchitto, Domenico Alvaro, Marco Marzioni, Paolo Onori, Romina Mancinelli, Eugenio Gaudio, Shannon Glaser, Gianfranco Alpini

Lab Invest. Author manuscript; available in PMC 2019 Jan 5.

Published in final edited form as: Lab Invest. 2018 Nov; 98(11): 1449–1464. Published online 2018 Jul 5. doi: 10.1038/s41374-018-0093-9

PMCID:: PMC6214714

Abstract Article PDF–3.5M

Select item 61689677.

The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1–Mediated Biliary Senescence

Nan Wu, Fanyin Meng, Tianhao Zhou, Julie Venter, Thao K. Giang, Konstantina Kyritsi, Chaodong Wu, Domenico Alvaro, Paolo Onori, Romina Mancinelli, Eugenio Gaudio, Heather Francis, Gianfranco Alpini, Shannon Glaser, Antonio Franchitto

Am J Pathol. 2018 Oct; 188(10): 2264–2280. doi: 10.1016/j.ajpath.2018.06.015

PMCID:: PMC6168967

Abstract Article

Select item 43195598.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 43120059.

Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche

Pia Nyeng, Maureen Ann Bjerke, Gitte Anker Norgaard, Xiaoling Qu, Sune Kobberup, Jan Jensen

Dev Biol. Author manuscript; available in PMC 2015 Jan 30.

Published in final edited form as: Dev Biol. 2011 Jan 1; 349(1): 20–34. Published online 2010 Sep 27. doi: 10.1016/j.ydbio.2010.09.010

PMCID:: PMC4312005

Abstract Article PDF–2.1M

Select item 401672010.

Progesterone Regulates Secretin Expression in Mouse Uterus During Early Pregnancy

Zhu Huang, Tong-Song Wang, Qian-Rong Qi, Ru-Juan Zuo, Xiao-Huan Liang, Xu-Yu Zhao, Zeng-Ming Yang

Reprod Sci. 2014 Jun; 21(6): 724–732. doi: 10.1177/1933719113512527

PMCID:: PMC4016720

Abstract Article PDF–580K

Select item 398854911.

The Knockout of Secretin in Cerebellar Purkinje Cells Impairs Mouse Motor Coordination and Motor Learning

Li Zhang, Sookja Kim Chung, Billy Kwok Chong Chow

Neuropsychopharmacology. 2014 May; 39(6): 1460–1468. Prepublished online 2013 Dec 19. Published online 2014 Feb 12. doi: 10.1038/npp.2013.344

PMCID:: PMC3988549

Abstract Article PDF–647K

Select item 396843212.

Pak3 Promotes Cell Cycle Exit and Differentiation of β-Cells in the Embryonic Pancreas and Is Necessary to Maintain Glucose Homeostasis in Adult Mice

Julie Piccand, Aline Meunier, Carole Merle, Zhengping Jia, Jean-Vianney Barnier, Gérard Gradwohl

Diabetes. 2014 Jan; 63(1): 203–215. Published online 2013 Dec 13. doi: 10.2337/db13-0384

PMCID:: PMC3968432

Abstract Article PDF–1.9M

Select item 388665813.

Lipolytic actions of secretin in mouse adipocytes

Revathi Sekar, Billy K. C. Chow

J Lipid Res. 2014 Feb; 55(2): 190–200. doi: 10.1194/jlr.M038042

PMCID:: PMC3886658

Abstract Article PDF–1.5M

Select item 372597314.

Global hormone profiling of murine placenta reveals Secretin expression

K. Knox, D. Leuenberger, A.A. Penn, J.C. Baker

Placenta. Author manuscript; available in PMC 2013 Jul 29.

Published in final edited form as: Placenta. 2011 Nov; 32(11): 811–816. Published online 2011 Sep 25. doi: 10.1016/j.placenta.2011.08.013

PMCID:: PMC3725973

Abstract Article PDF–1.5M

Select item 357429115.

CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin

Sinju Sundaresan, Rafiq Shahid, Terrence E. Riehl, Rashmi Chandra, Fatiha Nassir, William F. Stenson, Rodger A. Liddle, Nada A. Abumrad

FASEB J. 2013 Mar; 27(3): 1191–1202. doi: 10.1096/fj.12-217703

PMCID:: PMC3574291

Abstract Article

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163