PMC Links for GEO Profiles (Select 5668174) - PMC

Lukas Zierke, Daniel John, Marcel Gischke, Quang Trung Tran, Matthias Sendler, Frank Ulrich Weiss, Uwe T. Bornscheuer, Christoph Ritter, Markus M. Lerch, Ali A. Aghdassi

Cell Mol Life Sci. 2024 Dec; 81(1): 207. Published online 2024 May 6. doi: 10.1007/s00018-024-05247-7

PMCID:: PMC11074023

Abstract Article PDF–6.5M

Select item 110037435.

Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

Preksha Gaur, Yesheswini Rajendran, Bhagyashree Srivastava, Manasvini Markandey, Vered Fishbain-Yoskovitz, Gayatree Mohapatra, Aamir Suhail, Shikha Chaudhary, Shaifali Tyagi, Subhash Chandra Yadav, Amit Kumar Pandey, Yifat Merbl, Avinash Bajaj, Vineet Ahuja, Chittur Srikanth

eLife. 2024; 12: RP89776. Published online 2024 Apr 9. doi: 10.7554/eLife.89776

PMCID:: PMC11003743

Abstract Article PDF–11M

Select item 108643636.

Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy

Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng

Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2

PMCID:: PMC10864363

Abstract Article PDF–9.9M

Select item 108368027.

RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

Bryce Piper, Srimathi Bogamuwa, Tanvir Hossain, Daniela Farkas, Lorena Rosas, Adam C. Green, Geoffrey Newcomb, Nuo Sun, Jose A. Ovando-Ricardez, Jeffrey C. Horowitz, Aneel R. Bhagwani, Hu Yang, Tatiana V. Kudryashova, Mauricio Rojas, Ana L. Mora, Pearlly Yan, Rama K. Mallampalli, Elena A. Goncharova, David M. Eckmann, Laszlo Farkas

J Clin Invest. 2024 Feb 1; 134(3): e169441. Published online 2024 Feb 1. doi: 10.1172/JCI169441

PMCID:: PMC10836802

Abstract Article PDF–3.4M

Select item 107693508.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107161809.

Rab7 localized on zymogen granules is involved in maturation but not in autophagy or regulated exocytosis in pancreatic acinar cells

Kenichi Takahashi, Hirosato Mashima, Masanari Sekine, Takeshi Uehara, Takeharu Asano, Ge-Hong Sun-Wada, Yoh Wada, Hirohide Ohnishi

Sci Rep. 2023; 13: 22084. Published online 2023 Dec 12. doi: 10.1038/s41598-023-49520-4

PMCID:: PMC10716180

Abstract Article PDF–4.3M

Select item 1062289210.

Misregulation of mitochondria–lysosome contact dynamics in Charcot–Marie–Tooth Type 2B disease Rab7 mutant sensory peripheral neurons

Yvette C. Wong, Nirupa D. Jayaraj, Tayler B. Belton, George C. Shum, Hannah E. Ball, Dongjun Ren, Abigail L. D. Tadenev, Dimitri Krainc, Robert W. Burgess, Daniela M. Menichella

Proc Natl Acad Sci U S A. 2023 Oct 31; 120(44): e2313010120. Published online 2023 Oct 25. doi: 10.1073/pnas.2313010120

PMCID:: PMC10622892

Abstract Article PDF–14M

Select item 1043918311.

Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired

Wenjing Liang, Shakti Sagar, Rishith Ravindran, Rita H. Najor, Justin M. Quiles, Liguo Chi, Rachel Y. Diao, Benjamin P. Woodall, Leonardo J. Leon, Erika Zumaya, Jason Duran, David M. Cauvi, Antonio De Maio, Eric D. Adler, Åsa B. Gustafsson

Nat Commun. 2023; 14: 5031. Published online 2023 Aug 18. doi: 10.1038/s41467-023-40680-5

PMCID:: PMC10439183

Abstract Article PDF–7.6M

Select item 1035615712.

Disruption of the Rab7-Dependent Final Common Pathway of Endosomal and Autophagic Processing Results in a Severe Podocytopathy

Kristin Vöing, Ulf Michgehl, Nils David Mertens, Cara Picciotto, Mee-Ling Maywald, Jonas Goretzko, Sofie Waimann, Kevin Gilhaus, Manuel Rogg, Christoph Schell, Jürgen Klingauf, Yaroslav Tsytsyura, Uwe Hansen, Veerle van Marck, Aimee L. Edinger, Beate Vollenbröker, Ursula Rescher, Daniela Anne Braun, Britta George, Thomas Weide, Hermann Pavenstädt

J Am Soc Nephrol. 2023 Jul; 34(7): 1191–1206. Published online 2023 Apr 5. doi: 10.1681/ASN.0000000000000126

PMCID:: PMC10356157

Abstract Article

Select item 1030785213.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 992612414.

Loss of small GTPase Rab7 activation in prion infection negatively affects a feedback loop regulating neuronal cholesterol metabolism

Pearl Cherry, Li Lu, Su Yeon Shim, Vincent Ebacher, Waqas Tahir, Hermann M. Schatzl, Samia Hannaoui, Sabine Gilch

J Biol Chem. 2023 Feb; 299(2): 102883. Published online 2023 Jan 7. doi: 10.1016/j.jbc.2023.102883

PMCID:: PMC9926124

Abstract Article PDF–5.7M

Select item 988839315.

PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination

Xinfang Yu, Wei Li, Haidan Liu, Xu Wang, Cristian Coarfa, Chao Cheng, Xinlian Yu, Zhaoyang Zeng, Ya Cao, Ken H. Young, Yong Li

J Clin Invest. 2023 Feb 1; 133(3): e160456. Published online 2023 Feb 1. doi: 10.1172/JCI160456

PMCID:: PMC9888393

Abstract Article PDF–5.0M

Select item 939130116.

Borcs6 is required for endo-lysosomal degradation during early development

Charlotte J. Bell, Neha Gupta, Kimberly D. Tremblay, Jesse Mager

Mol Reprod Dev. Author manuscript; available in PMC 2023 Aug 1.

Published in final edited form as: Mol Reprod Dev. 2022 Aug; 89(8): 337–350. Published online 2022 Jun 21. doi: 10.1002/mrd.23626

PMCID:: PMC9391301

Abstract Article PDF–2.8M

Select item 901455917.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 900005918.

TMED2 binding restricts SMO to the ER and Golgi compartments

Giulio Di Minin, Markus Holzner, Alice Grison, Charles E. Dumeau, Wesley Chan, Asun Monfort, Loydie A. Jerome-Majewska, Henk Roelink, Anton Wutz

PLoS Biol. 2022 Mar; 20(3): e3001596. Published online 2022 Mar 30. doi: 10.1371/journal.pbio.3001596

PMCID:: PMC9000059

Abstract Article PDF–4.1M

Select item 872660819.

CREG1 promotes lysosomal biogenesis and function

Jie Liu, Yanmei Qi, Joshua Chao, Pranav Sathuvalli, Leonard Y. Lee, Shaohua Li

Autophagy. 2021; 17(12): 4249–4265. Published online 2021 May 8. doi: 10.1080/15548627.2021.1909997

PMCID:: PMC8726608

Abstract Article PDF–9.2M

Select item 848125020.

Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm

Ge-Hong Sun-Wada, Hiroyuki Tabata, Yoh Wada

Sci Rep. 2021; 11: 19355. Published online 2021 Sep 29. doi: 10.1038/s41598-021-98952-3

PMCID:: PMC8481250

Abstract Article PDF–3.5M

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