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Select item 111155491.

Bimodal expression of Sprouty2 during the cell cycle is mediated by phase-specific Ras/MAPK and c-Cbl activities

Christoph-Erik Mayer, Barbara Haigl, Florian Jantscher, Gerald Siegwart, Michael Grusch, Walter Berger, Hedwig Sutterlüty

Cell Mol Life Sci. 2010 Oct; 67(19): 3299–3311. Published online 2010 May 12. doi: 10.1007/s00018-010-0379-6

PMCID:: PMC11115549

Abstract Article PDF–796K

Select item 110922602.

PSMD9 promotes the malignant progression of hepatocellular carcinoma by interacting with c-Cbl to activate EGFR signaling and recycling

Yuting Su, Lili Meng, Chao Ge, Yuqi Liu, Chi Zhang, Yue Yang, Wei Tian, Hua Tian

J Exp Clin Cancer Res. 2024; 43: 142. Published online 2024 May 14. doi: 10.1186/s13046-024-03062-3

Correction in:: J Exp Clin Cancer Res. 2024; 43: 287.

PMCID:: PMC11092260

Abstract Article PDF–6.6M

Select item 109586753.

SERPINE2 promotes liver cancer metastasis by inhibiting c‐Cbl‐mediated EGFR ubiquitination and degradation

Shiyu Zhang, Xing Jia, Haojiang Dai, Xingxin Zhu, Wenfeng Song, Suchen Bian, Hao Wu, Shinuo Chen, Yangbo Tang, Junran Chen, Cheng Jin, Mengqiao Zhou, Haiyang Xie, Shusen Zheng, Penghong Song

Cancer Commun (Lond) 2024 Mar; 44(3): 384–407. Published online 2024 Feb 26. doi: 10.1002/cac2.12527

PMCID:: PMC10958675

Abstract Article PDF–15M

Select item 108489404.

Cbl and Cbl-b independently regulate EGFR through distinct receptor interaction modes

Itziar Pinilla-Macua, Alexander Sorkin

Mol Biol Cell. 2023 Dec 1; 34(13): ar134. Published online 2023 Nov 21. doi: 10.1091/mbc.E23-02-0058

PMCID:: PMC10848940

Abstract Article PDF–5.2M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101773326.

Inhibition of PLK1 Destabilizes EGFR and Sensitizes EGFR-Mutated Lung Cancer Cells to Small Molecule Inhibitor Osimertinib

Carolien Eggermont, Gustavo J. Gutierrez, Jacques De Grève, Philippe Giron

Cancers (Basel) 2023 May; 15(9): 2589. Published online 2023 May 2. doi: 10.3390/cancers15092589

PMCID:: PMC10177332

Abstract Article PDF–2.5M

Select item 101211667.

Ahmed A. Z. Dawoud, William J. Tapper, Nicholas C. P. Cross

Sci Adv. 2023 Apr; 9(16): eade9746. Published online 2023 Apr 21. doi: 10.1126/sciadv.ade9746

PMCID:: PMC10121166

Abstract Article PDF–1.3M

Select item 100729068.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 98231319.

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth

David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz

J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766

PMCID:: PMC9823131

Abstract Article PDF–2.5M

Select item 974277410.

CBL通过泛素化降解NCK2抑制乳腺癌细胞的增殖和侵袭

宋筱羽, 肖斌, 陆景润, 张文武, 李锦潮, 竹昕, 孙朝晖, 李林海

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Nov 20; 42(11): 1594–1603. Chinese. doi: 10.12122/j.issn.1673-4254.2022.11.02

PMCID:: PMC9742774

Abstract Article PDF–2.8M

Select item 948193311.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 927928512.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 917141113.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 913298214.

Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy

Di Xiao, Xin Hu, Mei Peng, Jun Deng, Sichun Zhou, Simeng Xu, Jingtao Wu, Xiaoping Yang

Cell Death Dis. 2022 May; 13(5): 499. Published online 2022 May 25. doi: 10.1038/s41419-022-04937-z

PMCID:: PMC9132982

Abstract Article PDF–6.3M

Select item 911973615.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910523516.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151