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Select item 113162911.

The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response

Siri Sæterstad, Ann Elisabeth Østvik, Marianne Doré Hansen, Torunn Bruland, Atle van Beelen Granlund

J Transl Med. 2024; 22: 750. Published online 2024 Aug 9. doi: 10.1186/s12967-024-05532-w

Correction in:: J Transl Med. 2024; 22: 849.

PMCID:: PMC11316291

Abstract Article PDF–7.1M

Select item 112969142.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112099353.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 110703904.

A study of the association between single nucleotide polymorphisms of the endoplasmic reticulum aminopeptidase 2 (ERAP2) gene and the risk of ankylosing spondylitis in Egyptians

Randa Mohamed Ibrahim Mesahel, Dina Salem Fotoh, Mahmoud Mohammed Hadhoud, Mohamed Farag Ali Assar

Mol Biol Rep. 2024; 51(1): 614. Published online 2024 May 5. doi: 10.1007/s11033-024-09404-w

PMCID:: PMC11070390

Abstract Article PDF–1.4M

Select item 110305535.

Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma

Esther Kamphausen, Christiane Kellert, Tarish Abbas, Nadja Akkad, Stefan Tenzer, Graham Pawelec, Hansjoerg Schild, Peter van Endert, Barbara Seliger

Cancer Immunol Immunother. 2010 Aug; 59(8): 1273–1284. Published online 2010 Apr 24. doi: 10.1007/s00262-010-0856-7

PMCID:: PMC11030553

Abstract Article PDF–527K

Select item 107947816.

A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs

Wouter J. Venema, Sanne Hiddingh, Jorg van Loosdregt, John Bowes, Brunilda Balliu, Joke H. de Boer, Jeannette Ossewaarde-van Norel, Susan D. Thompson, Carl D. Langefeld, Aafke de Ligt, Lars T. van der Veken, Peter H.L. Krijger, Wouter de Laat, Jonas J.W. Kuiper

Cell Genom. 2024 Jan 10; 4(1): 100460. Published online 2023 Dec 5. doi: 10.1016/j.xgen.2023.100460

PMCID:: PMC10794781

Abstract Article PDF–4.2M

Select item 104881877.

ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes

Valentina Tedeschi, Giorgia Paldino, Josephine Alba, Emanuele Molteni, Fabiana Paladini, Rossana Scrivo, Mattia Congia, Alberto Cauli, Rosalba Caccavale, Marino Paroli, Manuela Di Franco, Loretta Tuosto, Rosa Sorrentino, Marco D’Abramo, Maria Teresa Fiorillo

Int J Mol Sci. 2023 Sep; 24(17): 13335. Published online 2023 Aug 28. doi: 10.3390/ijms241713335

PMCID:: PMC10488187

Abstract Article PDF–3.0M

Select item 99654928.

A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2

Brian Hur, Veronica Wong, Eun D. Lee

Int J Mol Sci. 2023 Feb; 24(4): 3454. Published online 2023 Feb 9. doi: 10.3390/ijms24043454

PMCID:: PMC9965492

Abstract Article PDF–323K

Select item 97744889.

The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities

Adrian Martín-Esteban, Jesus Contreras Rodriguez, David Peske, Jose A. Lopez de Castro, Nilabh Shastri, Scheherazade Sadegh-Nasseri

Front Immunol. 2022; 13: 1066483. Published online 2022 Dec 8. doi: 10.3389/fimmu.2022.1066483

PMCID:: PMC9774488

Abstract Article PDF–1.7M

Select item 959620610.

ERAP2 as a potential biomarker for predicting gemcitabine response in patients with pancreatic cancer

Pian Yu, Shifu Luo, Jiaxin Cai, Jie Li, Cong Peng

Aging (Albany NY) 2022 Oct 15; 14(19): 7941–7958. Published online 2022 Oct 8. doi: 10.18632/aging.204324

PMCID:: PMC9596206

Abstract Article PDF–1.5M

Select item 872599511.

ERAP2 Is Associated With Immune Infiltration and Predicts Favorable Prognosis in SqCLC

Zhenlin Yang, He Tian, Fenglong Bie, Jiachen Xu, Zheng Zhou, Junhui Yang, Renda Li, Yue Peng, Guangyu Bai, Yanhua Tian, Ying Chen, Lei Liu, Tao Fan, Chu Xiao, Yujia Zheng, Bo Zheng, Jie Wang, Chunxiang Li, Shugeng Gao, Jie He

Front Immunol. 2021; 12: 788985. Published online 2021 Dec 21. doi: 10.3389/fimmu.2021.788985

PMCID:: PMC8725995

Abstract Article PDF–23M

Select item 857251012.

ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers

Sahar Gelfman, Dominique Monnet, Ann J. Ligocki, Thierry Tabary, Arden Moscati, Xiaodong Bai, Jan Freudenberg, Blerta Cooper, Jack A. Kosmicki, Sarah Wolf, Manuel A. R. Ferreira, John Overton, Jonathan Weyne, Eli A. Stahl, Aris Baras, Carmelo Romano, Jacques H. M. Cohen, Giovanni Coppola, Antoine Brézin, for the Regeneron Genetics Center

Invest Ophthalmol Vis Sci. 2021 Nov; 62(14): 3. Published online 2021 Nov 2. doi: 10.1167/iovs.62.14.3

PMCID:: PMC8572510

Abstract Article PDF–1.1M

Select item 839533613.

Overexpression of ERAP2N in Human Trophoblast Cells Promotes Cell Death

Kristen Lospinoso, Mikhail Dozmorov, Nadine El Fawal, Rhea Raghu, Wook-Jin Chae, Eun D. Lee

Int J Mol Sci. 2021 Aug; 22(16): 8585. Published online 2021 Aug 10. doi: 10.3390/ijms22168585

PMCID:: PMC8395336

Abstract Article PDF–2.4M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 799095615.

Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women

Leonardo Capistrano Ferreira, Carlos Eduardo Maia Gomes, Priya Duggal, Ingrid De Paula Holanda, Amanda Samara de Lima, Paulo Ricardo Porfírio do Nascimento, Selma Maria Bezerra Jeronimo

Sci Rep. 2021; 11: 6764. Published online 2021 Mar 24. doi: 10.1038/s41598-021-86240-z

PMCID:: PMC7990956

Abstract Article PDF–1.1M

Select item 798052816.

ERAPs Reduce In Vitro HIV Infection by Activating Innate Immune Response

Irma Saulle, Ivana Marventano, Marina Saresella, Claudia Vanetti, Micaela Garziano, Claudio Fenizia, Daria Trabattoni, Mario Clerici, Mara Biasin

J Immunol. 2021 Apr 1; 206(7): 1609–1617. Published online 2021 Feb 22. doi: 10.4049/jimmunol.2000991

PMCID:: PMC7980528

Abstract Article PDF–740K

Select item 795031617.

ERAP2 Increases the Abundance of a Peptide Submotif Highly Selective for the Birdshot Uveitis-Associated HLA-A29

Wouter J. Venema, Sanne Hiddingh, Joke H. de Boer, Frans H. J. Claas, Arend Mulder, Anneke I. den Hollander, Efstratios Stratikos, Siranush Sarkizova, Lars T. van der Veken, George M. C. Janssen, Peter A. van Veelen, Jonas J. W. Kuiper

Front Immunol. 2021; 12: 634441. Published online 2021 Feb 25. doi: 10.3389/fimmu.2021.634441

PMCID:: PMC7950316

Abstract Article PDF–3.8M

Select item 756352218.

A New ERAP2/Iso3 Isoform Expression Is Triggered by Different Microbial Stimuli in Human Cells. Could It Play a Role in the Modulation of SARS-CoV-2 Infection?

Irma Saulle, Claudia Vanetti, Sara Goglia, Chiara Vicentini, Enrico Tombetti, Micaela Garziano, Mario Clerici, Mara Biasin

Cells. 2020 Sep; 9(9): 1951. Published online 2020 Aug 24. doi: 10.3390/cells9091951

PMCID:: PMC7563522

Abstract Article PDF–1.8M

Select item 752525219.

Association of ERAP2 polymorphisms in Colombian HLA-B27+ or HLA-B15+ patients with SpA and its relationship with clinical presentation: axial or peripheral predominance

John Londono, Ana M Santos, Juan C Rueda, Enrique Calvo-Paramo, Ruben Burgos-Vargas, Gilberto Vargas-Alarcon, Nancy Martinez-Rodriguez, Sofia Arias-Correal, Guisselle-Nathalia Muñoz, Diana Padilla, Francy Cuervo, Viviana Reyes-Martinez, Santiago Bernal-Macías, Catalina Villota-Eraso, Luz M Avila-Portillo, Consuelo Romero, Juan F Medina

RMD Open. 2020; 6(2): e001250. Published online 2020 Sep 11. doi: 10.1136/rmdopen-2020-001250

PMCID:: PMC7525252

Abstract Article PDF–493K

Select item 739249120.

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

Ann Rheum Dis. 2020 Aug; 79(8): 1111–1120. Published online 2020 May 14. doi: 10.1136/annrheumdis-2019-216911

PMCID:: PMC7392491

Abstract Article PDF–14M

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