PMC Links for GEO Profiles (Select 56773357) - PMC

Select item 80893821.

Cytotoxic Lymphocytes Target HIV-1 Gag Through Granzyme M-Mediated Cleavage

Elisa Saccon, Flora Mikaeloff, Pol Figueras Ivern, Ákos Végvári, Anders Sönnerborg, Ujjwal Neogi, Robert van Domselaar

Front Immunol. 2021; 12: 669347. Published online 2021 Apr 19. doi: 10.3389/fimmu.2021.669347

PMCID:: PMC8089382

Select item 71799292.

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner

Liling Shan, Shuang Li, Jan Meeldijk, Bernadet Blijenberg, Astrid Hendriks, Karlijn J. W. M. van Boxtel, Sara P. H. van den Berg, Ian J. Groves, Martin Potts, Adriana Svrlanska, Thomas Stamminger, Mark R. Wills, Niels Bovenschen

PLoS Pathog. 2020 Apr; 16(4): e1008426. Published online 2020 Apr 13. doi: 10.1371/journal.ppat.1008426

PMCID:: PMC7179929

Abstract Article PDF–3.2M

Select item 71699833.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 49733544.

Granzyme M has a critical role in providing innate immune protection in ulcerative colitis

F Souza-Fonseca-Guimaraes, Y Krasnova, T Putoczki, K Miles, K P MacDonald, L Town, W Shi, G C Gobe, L McDade, L A Mielke, H Tye, S L Masters, G T Belz, N D Huntington, G Radford-Smith, M J Smyth

Cell Death Dis. 2016 Jul; 7(7): e2302. Published online 2016 Jul 21. doi: 10.1038/cddis.2016.215

PMCID:: PMC4973354

Abstract Article PDF–2.2M

Select item 48801505.

Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling

Christoph H. Emmerich, Siddharth Bakshi, Ian R. Kelsall, Juanma Ortiz-Guerrero, Natalia Shpiro, Philip Cohen

Biochem Biophys Res Commun. 2016 Jun 3; 474(3): 452–461. doi: 10.1016/j.bbrc.2016.04.141

PMCID:: PMC4880150

Abstract Article PDF–2.4M

Select item 35699826.

Granzyme M targets host cell hnRNP K that is essential for human cytomegalovirus replication

R van Domselaar, S A H de Poot, E B M Remmerswaal, K W Lai, I J M ten Berge, N Bovenschen

Cell Death Differ. 2013 Mar; 20(3): 419–429. Published online 2012 Oct 26. doi: 10.1038/cdd.2012.132

PMCID:: PMC3569982

Abstract Article PDF–3.0M

Select item 33079757.

FADD cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase cascade

S Wang, P Xia, L Shi, Z Fan

Cell Death Differ. 2012 Apr; 19(4): 605–615. Published online 2011 Oct 7. doi: 10.1038/cdd.2011.130

PMCID:: PMC3307975

Abstract Article PDF–819K

Select item 31647178.

Cleavage of von Willebrand Factor by Granzyme M Destroys Its Factor VIII Binding Capacity

Martine J. Hollestelle, Ka Wai Lai, Marcel van Deuren, Peter J. Lenting, Philip G. de Groot, Tom Sprong, Niels Bovenschen

PLoS One. 2011; 6(9): e24216. Published online 2011 Sep 1. doi: 10.1371/journal.pone.0024216

PMCID:: PMC3164717

Abstract Article PDF–423K

Select item 31522969.

Intracellular Serine Protease Inhibitor SERPINB4 Inhibits Granzyme M-Induced Cell Death

Pieter J. A. de Koning, J. Alain Kummer, Stefanie A. H. de Poot, Razi Quadir, Roel Broekhuizen, Anne F. McGettrick, Wayne J. Higgins, Bart Devreese, D. Margaret Worrall, Niels Bovenschen

PLoS One. 2011; 6(8): e22645. Published online 2011 Aug 3. doi: 10.1371/journal.pone.0022645