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Select item 111931431.

Conditional Knockouts of Interphotoreceptor Retinoid Binding Protein Suggest Two Independent Mechanisms for Retinal Degeneration and Myopia

Tatiana E. Getz, Micah A. Chrenek, Jack T. Papania, Debresha A. Shelton, Shanu Markand, P. Michael Iuvone, Zbynek Kozmik, Jeffrey H. Boatright, John M. Nickerson

Invest Ophthalmol Vis Sci. 2024 Jun; 65(6): 32. Published online 2024 Jun 21. doi: 10.1167/iovs.65.6.32

PMCID:: PMC11193143

Abstract Article PDF–11M

Select item 103419852.

Retinal Responses to Visual Stimuli in Interphotoreceptor Retinoid Binding-Protein Knock-Out Mice

Marci L. DeRamus, Jessica V. Jasien, Jess M. Eppstein, Pravallika Koala, Timothy W. Kraft

Int J Mol Sci. 2023 Jul; 24(13): 10655. Published online 2023 Jun 26. doi: 10.3390/ijms241310655

PMCID:: PMC10341985

Abstract Article PDF–3.1M

Select item 103078523.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 96038604.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 80186525.

Identification of MFRP and the secreted serine proteases PRSS56 and ADAMTS19 as part of a molecular network involved in ocular growth regulation

Swanand Koli, Cassandre Labelle-Dumais, Yin Zhao, Seyyedhassan Paylakhi, K. Saidas Nair

PLoS Genet. 2021 Mar; 17(3): e1009458. Published online 2021 Mar 23. doi: 10.1371/journal.pgen.1009458

PMCID:: PMC8018652

Abstract Article PDF–2.9M

Select item 72270286.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 67926887.

Early Onset Photoreceptor Abnormalities Induced by Targeted Disruption of the Interphotoreceptor Retinoid-Binding Protein Gene

Gregory I. Liou, Yijian Fei, Neal S. Peachey, Suraporn Matragoon, Shuanghong Wei, William S. Blaner, Youxiang Wang, Chengyu Liu, Max E. Gottesman, Harris Ripps

J Neurosci. 1998 Jun 15; 18(12): 4511–4520. doi: 10.1523/JNEUROSCI.18-12-04511.1998

PMCID:: PMC6792688

Abstract Article PDF–651K

Select item 66325818.

Blimp1 Suppresses Chx10 Expression in Differentiating Retinal Photoreceptor Precursors to Ensure Proper Photoreceptor Development

Kimiko Katoh, Yoshihiro Omori, Akishi Onishi, Shigeru Sato, Mineo Kondo, Takahisa Furukawa

J Neurosci. 2010 May 12; 30(19): 6515–6526. doi: 10.1523/JNEUROSCI.0771-10.2010

PMCID:: PMC6632581

Abstract Article PDF–2.2M

Select item 57669409.

Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium

Jeremy D. Cook, Sze Yin Ng, Marcia Lloyd, Shannan Eddington, Hui Sun, Jeremy Nathans, Dean Bok, Roxana A. Radu, Gabriel H. Travis

J Biol Chem. 2017 Dec 29; 292(52): 21407–21416. Published online 2017 Nov 6. doi: 10.1074/jbc.M117.812701

PMCID:: PMC5766940

Abstract Article PDF–1.9M

Select item 570267410.

Interphotoreceptor retinoid–binding protein removes all-trans-retinol and retinal from rod outer segments, preventing lipofuscin precursor formation

Chunhe Chen, Leopold Adler, IV, Patrice Goletz, Federico Gonzalez-Fernandez, Debra A. Thompson, Yiannis Koutalos

J Biol Chem. 2017 Nov 24; 292(47): 19356–19365. Published online 2017 Sep 28. doi: 10.1074/jbc.M117.795187

PMCID:: PMC5702674

Abstract Article PDF–1.3M

Select item 482437611.

Interphotoreceptor Retinoid-Binding Protein Mitigates Cellular Oxidative Stress and Mitochondrial Dysfunction Induced by All-trans-Retinal

Minsup Lee, Songhua Li, Kota Sato, Minghao Jin

Invest Ophthalmol Vis Sci. 2016 Apr; 57(4): 1553–1562. Published online 2016 Apr 5. doi: 10.1167/iovs.15-18551

PMCID:: PMC4824376

Abstract Article PDF–1.2M

Select item 458297112.

A novel pathogenic RBP-3 peptide reveals epitope spreading in persistent experimental autoimmune uveoretinitis

Joanne Boldison, Tarnjit K Khera, David A Copland, Madeleine L Stimpson, Gemma L Crawford, Andrew D Dick, Lindsay B Nicholson

Immunology. 2015 Oct; 146(2): 301–311. Published online 2015 Aug 11. doi: 10.1111/imm.12503

PMCID:: PMC4582971

Abstract Article PDF–643K

Select item 454474213.

Microbiota-dependent activation of an autoreactive T cell receptor provokes autoimmunity in an immunologically privileged site

Reiko Horai, Carlos R. Zárate-Bladés, Patricia Dillenburg-Pilla, Jun Chen, Jennifer L. Kielczewski, Phyllis B. Silver, Yingyos Jittayasothorn, Chi-Chao Chan, Hidehiro Yamane, Kenya Honda, Rachel R. Caspi

Immunity. Author manuscript; available in PMC 2016 Aug 18.

Published in final edited form as: Immunity. 2015 Aug 18; 43(2): 343–353. doi: 10.1016/j.immuni.2015.07.014

PMCID:: PMC4544742

Abstract Article PDF–1.8M

Select item 430160014.

Methodologies for analysis of patterning in the mouse RPE sheet

Jeffrey H. Boatright, Nupur Dalal, Micah A. Chrenek, Christopher Gardner, Alison Ziesel, Yi Jiang, Hans E. Grossniklaus, John M. Nickerson

Mol Vis. 2015; 21: 40–60. Published online 2015 Jan 15.

PMCID:: PMC4301600

Abstract Article PDF–8.5M

Select item 407721415.

Major Role of γδ T Cells in the Generation of IL-17⁺ Uveitogenic T Cells

Yan Cui, Hui Shao, Chen Lan, Hong Nian, Rebecca L. O'Brien, Willi K. Born, Henry J. Kaplan, Deming Sun

J Immunol. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: J Immunol. 2009 Jul 1; 183(1): 560–567. doi: 10.4049/jimmunol.0900241

PMCID:: PMC4077214

Abstract Article PDF–2.7M

Select item 381251016.

Receptor Interacting Protein Kinase-Mediated Necrosis Contributes to Cone and Rod Photoreceptor Degeneration in the Retina Lacking Interphotoreceptor Retinoid-Binding Protein

Kota Sato, Songhua Li, William C. Gordon, Jibao He, Gregory I. Liou, James M. Hill, Gabriel H. Travis, Nicolas G. Bazan, Minghao Jin

J Neurosci. 2013 Oct 30; 33(44): 17458–17468. doi: 10.1523/JNEUROSCI.1380-13.2013

PMCID:: PMC3812510

Abstract Article PDF–3.3M

Select item 369619417.

Normal Cone Function Requires the Interphotoreceptor Retinoid Binding Protein

Ryan O. Parker, Jie Fan, John M. Nickerson, Gregory I. Liou, Rosalie K. Crouch

J Neurosci. 2009 Apr 8; 29(14): 4616–4621. doi: 10.1523/JNEUROSCI.0063-09.2009

PMCID:: PMC3696194

Abstract Article PDF–552K

Select item 363084218.

Secretory Defect and Cytotoxicity: THE POTENTIAL DISEASE MECHANISMS FOR THE RETINITIS PIGMENTOSA (RP)-ASSOCIATED INTERPHOTORECEPTOR RETINOID-BINDING PROTEIN (IRBP)

Songhua Li, Zhihui Yang, Jane Hu, William C. Gordon, Nicolas G. Bazan, Arthur L. Haas, Dean Bok, Minghao Jin

J Biol Chem. 2013 Apr 19; 288(16): 11395–11406. Published online 2013 Mar 13. doi: 10.1074/jbc.M112.418251

PMCID:: PMC3630842

Abstract Article PDF–3.5M

Select item 335667419.

Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection

Ruth T. Taniguchi, Jason J. DeVoss, James J. Moon, John Sidney, Alessandro Sette, Marc K. Jenkins, Mark S. Anderson

Proc Natl Acad Sci U S A. 2012 May 15; 109(20): 7847–7852. Published online 2012 May 2. doi: 10.1073/pnas.1120607109

PMCID:: PMC3356674

Abstract Article PDF–1.0M

Select item 327360220.

The Living Eye “Disarms” Uncommitted Autoreactive T Cells by Converting Them to FoxP3⁺ Regulatory Cells Following Local Antigen Recognition

Ru Zhou, Reiko Horai, Phyllis B Silver, Mary J Mattapallil, Carlos R Zárate-Bladés, Wai Po Chong, Jun Chen, Rachael C Rigden, Rafael Villasmil, Rachel R Caspi

J Immunol. Author manuscript; available in PMC 2013 Feb 15.

Published in final edited form as: J Immunol. 2012 Feb 15; 188(4): 1742–1750. Published online 2012 Jan 11. doi: 10.4049/jimmunol.1102415