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Select item 113956111.

The KDR Gene rs2071559 and the VEGF Gene rs6921438 May Be Associated with Diabetic Nephropathy in Caucasians with Type 2 Diabetes Mellitus

Petra Nussdorfer, David Petrovič, Armin Alibegović, Ines Cilenšek, Danijel Petrovič

Int J Mol Sci. 2024 Sep; 25(17): 9439. Published online 2024 Aug 30. doi: 10.3390/ijms25179439

PMCID:: PMC11395611

Abstract Article PDF–4.0M

Select item 113527612.

Mutation in the Kinase Domain Alters the VEGFR2 Membrane Dynamics

Michela Corsini, Cosetta Ravelli, Elisabetta Grillo, Mattia Domenichini, Stefania Mitola

Cells. 2024 Aug; 13(16): 1346. Published online 2024 Aug 13. doi: 10.3390/cells13161346

PMCID:: PMC11352761

Abstract Article PDF–1.5M

Select item 112422593.

Lack of VEGFA/KDR Signaling in Conventional Renal Cell Carcinoma Explains the Low Efficacy of Target Therapy and Frequent Adverse Events

Lehel Peterfi, Maria V. Yusenko, Gyula Kovacs, Tamas Beothe

Int J Mol Sci. 2024 Jul; 25(13): 7359. Published online 2024 Jul 4. doi: 10.3390/ijms25137359

PMCID:: PMC11242259

Abstract Article PDF–1.4M

Select item 111996484.

The tyrosine kinase KDR is essential for the survival of HTLV-1-infected T cells by stabilizing the Tax oncoprotein

Suchitra Mohanty, Sujit Suklabaidya, Alfonso Lavorgna, Takaharu Ueno, Jun-ichi Fujisawa, Nyater Ngouth, Steven Jacobson, Edward W. Harhaj

Nat Commun. 2024; 15: 5380. Published online 2024 Jun 25. doi: 10.1038/s41467-024-49737-5

PMCID:: PMC11199648

Abstract Article PDF–4.4M

Select item 111596585.

Significance of phospho‐vascular endothelial growth factor receptor‐2 expression in pancreatic cancer

Yosuke Doi, Masakazu Yashiro, Nobuya Yamada, Ryosuke Amano, Go Ohira, Masahiro Komoto, Satoru Noda, Shinichiro Kashiwagi, Yukihiro Kato, Yuhiko Fuyuhiro, Kosei Hirakawa

Cancer Sci. 2010 Jun; 101(6): 1529–1535. Published online 2010 Mar 15. doi: 10.1111/j.1349-7006.2010.01547.x

PMCID:: PMC11159658

Abstract Article PDF–452K

Select item 111593196.

Impact of vascular endothelial growth factor receptor 1, 2, and 3 expression on the outcome of patients with gastric cancer

Yoshinori Hirashima, Yasuhide Yamada, Junichi Matsubara, Daisuke Takahari, Natsuko Okita, Atsuo Takashima, Ken Kato, Tetsuya Hamaguchi, Kuniaki Shirao, Yasuhiro Shimada, Hirokazu Taniguchi, Tadakazu Shimoda

Cancer Sci. 2009 Feb; 100(2): 310–315. Published online 2008 Dec 7. doi: 10.1111/j.1349-7006.2008.01020.x

PMCID:: PMC11159319

Abstract Article PDF–301K

Select item 111585067.

(–)‐Epigallocatechin gallate suppresses the growth of human hepatocellular carcinoma cells by inhibiting activation of the vascular endothelial growth factor–vascular endothelial growth factor receptor axis

Yohei Shirakami, Masahito Shimizu, Seiji Adachi, Hiroyasu Sakai, Takayuki Nakagawa, Yoichi Yasuda, Hisashi Tsurumi, Yukihiko Hara, Hisataka Moriwaki

Cancer Sci. 2009 Oct; 100(10): 1957–1962. Published online 2009 Jun 4. doi: 10.1111/j.1349-7006.2009.01241.x

PMCID:: PMC11158506

Abstract Article PDF–1.2M

Select item 111576728.

High expression of DEC2 distinguishes chondroblastic osteosarcoma and promotes tumour growth by activating the VEGFC/VEGFR2 signalling pathway

Maimaitiaili Tuerxun, Xu Zheng, Jun Xu, Quanjun Yang, Ting Yuan, Changqing Zhang, Shumin Zhou

J Cell Mol Med. 2024 Jun; 28(11): e18462. Published online 2024 Jun 7. doi: 10.1111/jcmm.18462

PMCID:: PMC11157672

Abstract Article PDF–54M

Select item 111363359.

A VEGF-A splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2

S. Cébe Suarez, M. Pieren, L. Cariolato, S. Arn, U. Hoffmann, A. Bogucki, C. Manlius, J. Wood, K. Ballmer-Hofer

Cell Mol Life Sci. 2006 Sep; 63(17): 2067–2077. Published online 2006 Aug 11. doi: 10.1007/s00018-006-6254-9

PMCID:: PMC11136335

Abstract Article PDF–445K

Select item 1106709910.

VEGFR2 blockade inhibits glioblastoma cell proliferation by enhancing mitochondrial biogenesis

Min Guo, Junhao Zhang, Jiang Han, Yingyue Hu, Hao Ni, Juan Yuan, Yang Sun, Meijuan Liu, Lifen Gao, Wangjun Liao, Chunhong Ma, Yaou Liu, Shuijie Li, Nailin Li

J Transl Med. 2024; 22: 419. Published online 2024 May 3. doi: 10.1186/s12967-024-05155-1

PMCID:: PMC11067099

Abstract Article PDF–9.4M

Select item 1102970611.

P53, hTERT, WT-1, and VEGFR2 are the most suitable targets for cancer vaccine therapy in HLA-A24 positive pancreatic adenocarcinoma

Takeshi Terashima, Eishiro Mizukoshi, Kuniaki Arai, Tatsuya Yamashita, Mariko Yoshida, Hajime Ota, Ichiro Onishi, Masato Kayahara, Koushiro Ohtsubo, Takashi Kagaya, Masao Honda, Shuichi Kaneko

Cancer Immunol Immunother. 2014 May; 63(5): 479–489. Published online 2014 Mar 16. doi: 10.1007/s00262-014-1529-8

PMCID:: PMC11029706

Abstract Article PDF–892K

Select item 1100309512.

Proteomic studies of VEGFR2 in human placentas reveal protein associations with preeclampsia, diabetes, gravidity, and labor

Shannon J. Ho, Dale Chaput, Rachel G. Sinkey, Amanda H. Garces, Erika P. New, Maja Okuka, Peng Sang, Sefa Arlier, Nihan Semerci, Thora S. Steffensen, Thomas J. Rutherford, Angel E. Alsina, Jianfeng Cai, Matthew L. Anderson, Ronald R. Magness, Vladimir N. Uversky, Derek A. T. Cummings, John C. M. Tsibris

Cell Commun Signal. 2024; 22: 221. Published online 2024 Apr 9. doi: 10.1186/s12964-024-01567-0

PMCID:: PMC11003095

Abstract Article PDF–14M

Select item 1094137513.

Endothelial β-catenin upregulation and Y142 phosphorylation drive diabetic angiogenesis via upregulating KDR/HDAC9

Zhenfeng Chen, Bingqi Lin, Xiaodan Yao, Jie Weng, Jinlian Liu, Qi He, Ke Song, Chuyu Zhou, Zirui Zuo, Xiaoxia Huang, Zhuanhua Liu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo

Cell Commun Signal. 2024; 22: 182. Published online 2024 Mar 15. doi: 10.1186/s12964-024-01566-1

PMCID:: PMC10941375

Abstract Article PDF–16M

Select item 1087852714.

Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells

Sarvenaz Sarabipour, Karina Kinghorn, Kaitlyn M. Quigley, Anita Kovacs-Kasa, Brian H. Annex, Victoria L. Bautch, Feilim Mac Gabhann

PLoS Comput Biol. 2024 Feb; 20(2): e1011798. Published online 2024 Feb 7. doi: 10.1371/journal.pcbi.1011798

PMCID:: PMC10878527

Abstract Article PDF–3.0M

Select item 1076740515.

Association of KDR (rs2071559, rs1870377), CFH (rs1061170, rs1410996) genes variants and serum levels with pituitary adenoma

Akvile Bruzaite, Greta Gedvilaite, Loresa Kriauciuniene, Rasa Liutkeviciene

Mol Genet Genomic Med. 2024 Jan; 12(1): e2289. Published online 2023 Oct 6. doi: 10.1002/mgg3.2289

PMCID:: PMC10767405

Abstract Article PDF–893K

Select item 1071206516.

Biomechanical stimulation promotes blood vessel growth despite VEGFR-2 inhibition

Bronte Miller Johnson, Allison McKenzie Johnson, Michael Heim, Molly Buckley, Bryan Mortimer, Joel L. Berry, Mary Kathryn Sewell-Loftin

BMC Biol. 2023; 21: 290. Published online 2023 Dec 10. doi: 10.1186/s12915-023-01792-y

PMCID:: PMC10712065

Abstract Article PDF–1.5M

Select item 1061671317.

IL-36γ Augments Ocular Angiogenesis by Promoting the Vascular Endothelial Growth Factor–Vascular Endothelial Growth Factor Receptor Axis

WonKyung J. Cho, Elsayed Elbasiony, Aastha Singh, Sharad K. Mittal, Sunil K. Chauhan

Am J Pathol. 2023 Nov; 193(11): 1740–1749. doi: 10.1016/j.ajpath.2023.01.003

PMCID:: PMC10616713

Abstract Article PDF–2.2M

Select item 1057573318.

Endothelial VEGFR2-PLCγ signaling regulates vascular permeability and antitumor immunity through eNOS/Src

Elin Sjöberg, Marit Melssen, Mark Richards, Yindi Ding, Catarina Chanoca, Dongying Chen, Emmanuel Nwadozi, Sagnik Pal, Dominic T. Love, Takeshi Ninchoji, Masabumi Shibuya, Michael Simons, Anna Dimberg, Lena Claesson-Welsh

J Clin Invest. 2023 Oct 16; 133(20): e161366. Published online 2023 Oct 16. doi: 10.1172/JCI161366

PMCID:: PMC10575733

Abstract Article PDF–7.1M

Select item 1051416919.

PDGFRA, KIT, and KDR Gene Amplification in Glioblastoma: Heterogeneity and Clinical Significance

Bianca Soares Carlotto, Patricia Trevisan, Valentina Oliveira Provenzi, Fabiano Pasqualotto Soares, Rafael Fabiano Machado Rosa, Marileila Varella-Garcia, Paulo Ricardo Gazzola Zen

Neuromolecular Med. 2023; 25(3): 441–450. Published online 2023 Aug 23. doi: 10.1007/s12017-023-08749-y