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Items: 1 to 20 of 127

1.
Investigating the Link between STAT4 Genetic Variants, STAT4 Protein Concentrations, and Laryngeal Squamous Cell Carcinoma: A Comprehensive Analysis of Clinical Manifestations
Enrika Pileckaite, Alvita Vilkeviciute, Loresa Kriauciuniene, Vykintas Liutkevicius, Rasa Liutkeviciene
Int J Mol Sci. 2024 Sep; 25(18): 10180. Published online 2024 Sep 22. doi: 10.3390/ijms251810180
PMCID:
PMC11432593
AbstractArticlePDF–547K
2.
The Role of JAK-STAT-SOCS1 Axis in Tumorigenesis, Malignant Progression and Lymphatic Metastasis of Penile Cancer
Da-Ming Xu, Ling-Xiao Chen, Xiao-Yu Zhuang, Hui Han, Miao Mo
Int J Med Sci. 2024; 21(6): 1176–1186. Published online 2024 Apr 29. doi: 10.7150/ijms.95490
PMCID:
PMC11103387
AbstractArticlePDF–7.7M
3.
Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway
Bisheng Cheng, Lingfeng Li, Tianlong Luo, Qiong Wang, Yong Luo, Shoumin Bai, Kaiwen Li, Yiming Lai, Hai Huang
J Exp Clin Cancer Res. 2024; 43: 67. Published online 2024 Mar 1. doi: 10.1186/s13046-024-02962-8
PMCID:
PMC10905933
AbstractArticlePDF–7.0M
4.
STAT4 Gene Variant rs7574865 Is Associated with Rheumatoid Arthritis Activity and Anti-CCP Levels in the Western but Not in the Southern Population of Mexico
Karla Mayela Bravo-Villagra, José Francisco Muñoz-Valle, Christian Johana Baños-Hernández, Sergio Cerpa-Cruz, José Eduardo Navarro-Zarza, Isela Parra-Rojas, José Alonso Aguilar-Velázquez, Samuel García-Arellano, Andres López-Quintero
Genes (Basel) 2024 Feb; 15(2): 241. Published online 2024 Feb 14. doi: 10.3390/genes15020241
PMCID:
PMC10887563
AbstractArticlePDF–391K
5.
Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation
Gianluca Scarno, Julija Mazej, Mattia Laffranchi, Chiara Di Censo, Irene Mattiola, Arianna M. Candelotti, Giuseppe Pietropaolo, Helena Stabile, Cinzia Fionda, Giovanna Peruzzi, Stephen R. Brooks, Wanxia Li Tsai, Yohei Mikami, Giovanni Bernardini, Angela Gismondi, Silvano Sozzani, James P. Di Santo, Christian A. J. Vosshenrich, Andreas Diefenbach, Massimo Gadina, Angela Santoni, Giuseppe Sciumè
Proc Natl Acad Sci U S A. 2023 Oct 3; 120(40): e2306761120. Published online 2023 Sep 27. doi: 10.1073/pnas.2306761120
PMCID:
PMC10556635
AbstractArticlePDF–1.7M
6.
Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome
Hratch Baghdassarian, Sarah A. Blackstone, Owen S. Clay, Rachael Philips, Brynja Matthiasardottir, Michele Nehrebecky, Vivian K. Hua, Rachael McVicar, Yang Liu, Suzanne M. Tucker, Davide Randazzo, Natalie Deuitch, Sofia Rosenzweig, Adam Mark, Roman Sasik, Kathleen M. Fisch, Pallavi Pimpale Chavan, Elif Eren, Norman R. Watts, Chi A. Ma, Massimo Gadina, Daniella M. Schwartz, Anwesha Sanyal, Giffin Werner, David R. Murdock, Nobuyuki Horita, Shimul Chowdhury, David Dimmock, Kristen Jepsen, Elaine F. Remmers, Raphaela Goldbach-Mansky, William A. Gahl, John J. O’Shea, Joshua D. Milner, Nathan E. Lewis, Johanna Chang, Daniel L. Kastner, Kathryn Torok, Hirotsugu Oda, Christopher D. Putnam, Lori Broderick
N Engl J Med. Author manuscript; available in PMC 2023 Dec 15.
Published in final edited form as: N Engl J Med. 2023 Jun 15; 388(24): 2241–2252. Published online 2023 May 31. doi: 10.1056/NEJMoa2202318
PMCID:
PMC10392571
AbstractArticlePDF–2.4M
7.
STAT4, a potential predictor of prognosis, promotes CD8 T‑cell infiltration in ovarian serous carcinoma by inducing CCL5 secretion
Wei Wang, Si Liu, Funian Lu, Bin Yang, Xucui Zhuang, Jingjing Yin, Gang Chen, Chaoyang Sun
Oncol Rep. 2023 Jul; 50(1): 140. Published online 2023 May 31. doi: 10.3892/or.2023.8577
PMCID:
PMC10251369
AbstractArticlePDF–3.3M
8.
Defective binding of ETS1 and STAT4 due to a mutation in the promoter region of THPO as a novel mechanism of congenital amegakaryocytic thrombocytopenia
Valeria Capaci, Etai Adam, Ifat Bar-Joseph, Michela Faleschini, Alessandro Pecci, Anna Savoia
Haematologica. 2023 May 1; 108(5): 1385–1393. Published online 2022 Oct 13. doi: 10.3324/haematol.2022.281392
PMCID:
PMC10153527
AbstractArticlePDF–1.3M
9.
Association of the STAT4 Gene rs7574865 Polymorphism with IFN-γ Levels in Patients with Systemic Lupus Erythematosus
Yussef Esparza Guerrero, Maria Luisa Vazquez Villegas, Cesar Arturo Nava Valdivia, Juan Manuel Ponce Guarneros, Edsaul Emilio Perez Guerrero, Eli Efrain Gomez Ramirez, Melissa Ramirez Villafaña, Betsabe Contreras Haro, Alejandra Martinez Hernandez, Ernesto German Cardona Muñoz, Ismael Nuño Arana, Sergio Gabriel Gallardo Moya, Alfredo Celis, Laura Gonzalez Lopez, Jorge Ivan Gamez Nava, Ana Miriam Saldaña Cruz
Genes (Basel) 2023 Mar; 14(3): 537. Published online 2023 Feb 21. doi: 10.3390/genes14030537
PMCID:
PMC10048585
AbstractArticlePDF–610K
10.
T Cells With Activated STAT4 Drive the High-Risk Rejection State to Renal Allograft Failure After Kidney Transplantation
Yihan Chen, Bao Zhang, Tianliang Liu, Xiaoping Chen, Yaning Wang, Hongbo Zhang
Front Immunol. 2022; 13: 895762. Published online 2022 Jul 1. doi: 10.3389/fimmu.2022.895762
PMCID:
PMC9283858
AbstractArticlePDF–6.4M
11.
Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4
Fan Yang, Xue‐Qi Liu, Jian‐Zhong He, Shi‐Ping Xian, Peng‐Fei Yang, Zhi‐Ying Mai, Miao Li, Ye Liu, Xing‐Ding Zhang
J Cell Mol Med. 2022 Apr; 26(8): 2363–2376. Published online 2022 Feb 27. doi: 10.1111/jcmm.17257
PMCID:
PMC8995457
AbstractArticlePDF–2.0M
12.
Human transcription factor protein interaction networks
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo
Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5
PMCID:
PMC8828895
AbstractArticlePDF–1.7M
13.
Stat4 rs7574865 polymorphism promotes the occurrence and progression of hepatocellular carcinoma via the Stat4/CYP2E1/FGL2 pathway
Caie Wang, Na Gao, Lukui Yang, Yuanyuan Guo, Yan Fang, Tong Wang, Chen Xu, Gui fang Li, Jun Zhou, Yunfei Zhang, Qiang Wen, Hailing Qiao
Cell Death Dis. 2022 Feb; 13(2): 130. Published online 2022 Feb 8. doi: 10.1038/s41419-022-04584-4
PMCID:
PMC8826371
AbstractArticlePDF–5.3M
14.
Regional heritability mapping identifies several novel loci (STAT4, ULK4, and KCNH5) for primary biliary cholangitis in the Japanese population
Olivier Gervais, Kazuko Ueno, Yosuke Kawai, Yuki Hitomi, Yoshihiro Aiba, Mayumi Ueta, Minoru Nakamura, Katsushi Tokunaga, Masao Nagasaki
Eur J Hum Genet. 2021 Aug; 29(8): 1282–1291. Published online 2021 Apr 9. doi: 10.1038/s41431-021-00854-5
PMCID:
PMC8385030
AbstractArticlePDF–952K
15.
Interaction between the STAT4 rs11889341(T) risk allele and smoking confers increased risk of myocardial infarction and nephritis in patients with systemic lupus erythematosus
Sarah Reid, Niklas Hagberg, Johanna K Sandling, Andrei Alexsson, Pascal Pucholt, Christopher Sjöwall, Karoline Lerang, Andreas Jönsen, Iva Gunnarsson, Ann-Christine Syvänen, Anne Margrethe Troldborg, Anne Voss, Anders A Bengtsson, Øyvind Molberg, Søren Jacobsen, Elisabet Svenungsson, Lars Rönnblom, Dag Leonard
Ann Rheum Dis. 2021 Sep; 80(9): 1183–1189. Published online 2021 Mar 25. doi: 10.1136/annrheumdis-2020-219727
PMCID:
PMC8372395
AbstractArticlePDF–510K
16.
A new discovery of STAT4 single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Chinese Han population: a case–control study
Xu Chao, Jieqiong Wu, Wei Zhang, Xuesong Feng, Luyan Zhao, Feng Huang, Chao Jiang
Biosci Rep. 2021 Jul 30; 41(7): BSR20210124. Published online 2021 Jul 26. doi: 10.1042/BSR20210124
PMCID:
PMC8314431
AbstractArticlePDF–894K
17.
Association between STAT4 gene polymorphism and type 2 diabetes risk in Chinese Han population
Jiaqi Cui, Rui Tong, Jing Xu, Yanni Tian, Juan Pan, Ning Wang, Huan Chen, Yanqi Peng, Sijia Fei, Wang Ling, Chaoying Guo, Juanchuan Yao, Wei Cui
BMC Med Genomics. 2021; 14: 169. Published online 2021 Jun 27. doi: 10.1186/s12920-021-01000-2
PMCID:
PMC8237503
AbstractArticlePDF–1017K
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
Association of the STAT4, CDKN1A, and IRF5 variants with risk of lupus nephritis and renal biopsy classification in patients in Vietnam
Trung Dung Nghiem, Gia Tuyen Do, Long Hoang Luong, Quy Linh Nguyen, Ha Viet Dang, Anh Nguyen Viet, Thuy Thu Nguyen, Van Khanh Tran, Thanh Van Ta, Thinh Huy Tran
Mol Genet Genomic Med. 2021 Apr; 9(4): e1648. Published online 2021 Mar 9. doi: 10.1002/mgg3.1648
PMCID:
PMC8123735
AbstractArticlePDF–319K
20.
Heat shock transcription factor 1 is SUMOylated in the activated trimeric state
Szymon W. Kmiecik, Katarzyna Drzewicka, Frauke Melchior, Matthias P. Mayer
J Biol Chem. 2021 Jan-Jun; 296: 100324. Published online 2021 Jan 23. doi: 10.1016/j.jbc.2021.100324
PMCID:
PMC7949154
AbstractArticlePDF–2.3M

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