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Items: 1 to 20 of 52

1.
Identification and characterization of protein interactions with the major Niemann–Pick type C disease protein in yeast reveals pathways of therapeutic potential
Natalie Hammond, Jamie Snider, Igor Stagljar, Kevin Mitchell, Kirill Lagutin, Matthew Jessulat, Mohan Babu, Paul H Teesdale-Spittle, Jeffrey P Sheridan, Stephen L Sturley, Andrew B Munkacsi
Genetics. 2023 Sep; 225(1): iyad129. Published online 2023 Jul 13. doi: 10.1093/genetics/iyad129
PMCID:
PMC10471228
AbstractArticlePDF–32M
2.
The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions
Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman
Mol Cell. Author manuscript; available in PMC 2024 Jun 15.
Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021
PMCID:
PMC10297700
AbstractArticlePDF–2.0M
3.
ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast
Chiranjit Panja, Aneta Wiesyk, Katarzyna Niedźwiecka, Emilia Baranowska, Roza Kucharczyk
Sci Rep. 2023; 13: 3839. Published online 2023 Mar 7. doi: 10.1038/s41598-023-30966-5
PMCID:
PMC9992712
AbstractArticlePDF–8.1M
4.
Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation
Guido Barbieri, Julien Simon, Cristina R. Lupusella, Fabio Pereira, Francesco Elia, Hadar Meyer, Maya Schuldiner, Steven D. Hanes, Duy Nguyen, Volkhard Helms, Karin Römisch
J Biol Chem. 2023 Mar; 299(3): 102895. Published online 2023 Jan 11. doi: 10.1016/j.jbc.2023.102895
PMCID:
PMC9947333
AbstractArticlePDF–1.7M
5.
A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast
Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger
G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296
PMCID:
PMC9836348
AbstractArticlePDF–857K
6.
New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources
Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry
Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224
PMCID:
PMC9209811
AbstractArticlePDF–818K
7.
How does Sec63 affect the conformation of Sec61 in yeast?
Pratiti Bhadra, Lalitha Yadhanapudi, Karin Römisch, Volkhard Helms
PLoS Comput Biol. 2021 Mar; 17(3): e1008855. Published online 2021 Mar 29. doi: 10.1371/journal.pcbi.1008855
PMCID:
PMC8031780
AbstractArticlePDF–3.1M
8.
Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2
Ku-Feng Lin, Michelle Y. Fry, Shyam M. Saladi, William M. Clemons, Jr.
J Biol Chem. 2021 Jan-Jun; 296: 100441. Published online 2021 Feb 19. doi: 10.1016/j.jbc.2021.100441
PMCID:
PMC8010706
AbstractArticlePDF–3.1M
9.
Membrane phospholipid alteration causes chronic ER stress through early degradation of homeostatic ER-resident proteins
Peter Shyu, Jr., Benjamin S. H. Ng, Nurulain Ho, Ruijie Chaw, Yi Ling Seah, Charlie Marvalim, Guillaume Thibault
Sci Rep. 2019; 9: 8637. Published online 2019 Jun 14. doi: 10.1038/s41598-019-45020-6
PMCID:
PMC6572771
AbstractArticlePDF–4.7M
10.
The N-terminus of Sec61p plays key roles in ER protein import and ERAD
Francesco Elia, Lalitha Yadhanapudi, Thomas Tretter, Karin Römisch
PLoS One. 2019; 14(4): e0215950. Published online 2019 Apr 24. doi: 10.1371/journal.pone.0215950
PMCID:
PMC6481919
AbstractArticlePDF–1.5M
11.
Structure of the post-translational protein translocation machinery of the ER membrane
Xudong Wu, Cerrone Cabanos, Tom A. Rapoport
Nature. Author manuscript; available in PMC 2019 Jun 30.
Published in final edited form as: Nature. 2019 Feb; 566(7742): 136–139. Published online 2018 Dec 31. doi: 10.1038/s41586-018-0856-x
PMCID:
PMC6367035
AbstractArticlePDF–3.9M
12.
Conserved motifs on the cytoplasmic face of the protein translocation channel are critical for the transition between resting and active conformations
Elisabet C. Mandon, Cameron Butova, Amber Lachapelle, Reid Gilmore
J Biol Chem. 2018 Aug 31; 293(35): 13662–13672. Published online 2018 Jul 9. doi: 10.1074/jbc.RA118.004123
PMCID:
PMC6120202
AbstractArticlePDF–2.0M
13.
Substrate relay in an Hsp70‐cochaperone cascade safeguards tail‐anchored membrane protein targeting
Hyunju Cho, Shu‐ou Shan
EMBO J. 2018 Aug 15; 37(16): e99264. Published online 2018 Jul 4. doi: 10.15252/embj.201899264
PMCID:
PMC6092619
AbstractArticlePDF–2.4M
14.
A global interaction network maps a wiring diagram of cellular function
Michael Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, Anastasia Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Usaj, Julia Hanchard, Susan D. Lee, Vicent Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen-Yuan Lin, Elena Kuzmin, Justin Nelson, Jeff S. Piotrowski, Tharan Srikumar, Sondra Bahr, Yiqun Chen, Raamesh Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, Mojca Mattiazzi Usaj, Hiroki Okada, Natasha Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, Jamie Snider, Harsha Garadi Suresh, Yizhao Tan, Hongwei Zhu, Noel Malod-Dognin, Vuk Janjic, Natasa Przulj, Olga G. Troyanskaya, Igor Stagljar, Tian Xia, Yoshikazu Ohya, Anne-Claude Gingras, Brian Raught, Michael Boutros, Lars M. Steinmetz, Claire L. Moore, Adam P. Rosebrock, Amy A. Caudy, Chad L. Myers, Brenda Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Oct 30.
Published in final edited form as: Science. 2016 Sep 23; 353(6306): aaf1420. doi: 10.1126/science.aaf1420
PMCID:
PMC5661885
AbstractArticlePDF–2.6M
15.
Architecture and dynamics of overlapped RNA regulatory networks
Christopher P. Lapointe, Melanie A. Preston, Daniel Wilinski, Harriet A.J. Saunders, Zachary T. Campbell, Marvin Wickens
RNA. 2017 Nov; 23(11): 1636–1647. doi: 10.1261/rna.062687.117
PMCID:
PMC5648032
AbstractArticlePDF–6.6M
16.
The Genetic Landscape of a Cell
Michael Costanzo, Anastasia Baryshnikova, Jeremy Bellay, Yungil Kim, Eric D. Spear, Carolyn S. Sevier, Huiming Ding, Judice L.Y. Koh, Kiana Toufighi, Sara Mostafavi, Jeany Prinz, Robert P. St. Onge, Benjamin VanderSluis, Taras Makhnevych, Franco J. Vizeacoumar, Solmaz Alizadeh, Sondra Bahr, Renee L. Brost, Yiqun Chen, Murat Cokol, Raamesh Deshpande, Zhijian Li, Zhen-Yuan Lin, Wendy Liang, Michaela Marback, Jadine Paw, Bryan-Joseph San Luis, Ermira Shuteriqi, Amy Hin Yan Tong, Nydia van Dyk, Iain M. Wallace, Joseph A. Whitney, Matthew T. Weirauch, Guoqing Zhong, Hongwei Zhu, Walid A. Houry, Michael Brudno, Sasan Ragibizadeh, Balázs Papp, Csaba Pál, Frederick P. Roth, Guri Giaever, Corey Nislow, Olga G. Troyanskaya, Howard Bussey, Gary D. Bader, Anne-Claude Gingras, Quaid D. Morris, Philip M. Kim, Chris A. Kaiser, Chad L. Myers, Brenda J. Andrews, Charles Boone
Science. Author manuscript; available in PMC 2017 Sep 15.
Published in final edited form as: Science. 2010 Jan 22; 327(5964): 425–431. doi: 10.1126/science.1180823
PMCID:
PMC5600254
AbstractArticlePDF–2.4M
17.
The SND proteins constitute an alternative targeting route to the endoplasmic reticulum
Naama Aviram, Tslil Ast, Elizabeth A. Costa, Eric C. Arakel, Silvia G. Chuartzman, Calvin H. Jan, Sarah Haßdenteufel, Johanna Dudek, Martin Jung, Stefan Schorr, Richard Zimmermann, Blanche Schwappach, Jonathan S. Weissman, Maya Schuldiner
Nature. Author manuscript; available in PMC 2017 Jul 17.
Published in final edited form as: Nature. 2016 Nov 30; 540(7631): 134–138. doi: 10.1038/nature20169
PMCID:
PMC5513701
AbstractArticlePDF–1.2M
18.
Systematic Optimization of Protein Secretory Pathways in Saccharomyces cerevisiae to Increase Expression of Hepatitis B Small Antigen
Jiayuan Sheng, Hunter Flick, Xueyang Feng
Front Microbiol. 2017; 8: 875. Published online 2017 May 16. doi: 10.3389/fmicb.2017.00875
PMCID:
PMC5432677
AbstractArticlePDF–1.3M
19.
A novel translational control mechanism involving RNA structures within coding sequences
Jennifer Jungfleisch, Danny D. Nedialkova, Ivan Dotu, Katherine E. Sloan, Neus Martinez-Bosch, Lukas Brüning, Emanuele Raineri, Pilar Navarro, Markus T. Bohnsack, Sebastian A. Leidel, Juana Díez
Genome Res. 2017 Jan; 27(1): 95–106. doi: 10.1101/gr.209015.116
Correction in:
Genome Res. 2017 Apr; 27(4): 663.
PMCID:
PMC5204348
AbstractArticlePDF–1.3M
20.
Analysis of membrane proteins localizing to the inner nuclear envelope in living cells
Christine J. Smoyer, Santharam S. Katta, Jennifer M. Gardner, Lynn Stoltz, Scott McCroskey, William D. Bradford, Melainia McClain, Sarah E. Smith, Brian D. Slaughter, Jay R. Unruh, Sue L. Jaspersen
J Cell Biol. 2016 Nov 21; 215(4): 575–590. doi: 10.1083/jcb.201607043
PMCID:
PMC5119940
AbstractArticlePDF–3.2M

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