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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 110241852.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108997793.

The RNA helicase Dbp10 coordinates assembly factor association with PTC maturation during ribosome biogenesis

Valentin Mitterer, Hussein Hamze, Natalia Kunowska, Ulrich Stelzl, Anthony K Henras, Ed Hurt

Nucleic Acids Res. 2024 Feb 28; 52(4): 1975–1987. Published online 2023 Dec 19. doi: 10.1093/nar/gkad1206

PMCID:: PMC10899779

Abstract Article PDF–1.6M

Select item 108724774.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107988585.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001386.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 106390617.

Yeast ribosome biogenesis factors Puf6 and Nog2 and ribosomal proteins uL2 and eL43 act in concert to facilitate the release of nascent large ribosomal subunits from the nucleolus

Amber J LaPeruta, Stefanie Hedayati, Jelena Micic, Fiona Fitzgerald, David Kim, Grace Oualline, John L Woolford

Nucleic Acids Res. 2023 Nov 10; 51(20): 11277–11290. Published online 2023 Oct 9. doi: 10.1093/nar/gkad794

PMCID:: PMC10639061

Abstract Article PDF–3.7M

Select item 105211378.

Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress

Andreas Hadjicharalambous, Alex J. Whale, Geylani Can, J. Mark Skehel, Jonathan M. Houseley, Philip Zegerman

Version 1. Wellcome Open Res. 2023; 8: 327. Published online 2023 Jul 26. doi: 10.12688/wellcomeopenres.19617.1

PMCID:: PMC10521137

Abstract Article PDF–4.0M

Select item 102922109.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 950881910.

Rbp95 binds to 25S rRNA helix H95 and cooperates with the Npa1 complex during early pre-60S particle maturation

Priya Bhutada, Sébastien Favre, Mariam Jaafar, Jutta Hafner, Laura Liesinger, Stefan Unterweger, Karin Bischof, Barbara Darnhofer, Devanarayanan Siva Sankar, Gerald Rechberger, Raghida Abou Merhi, Simon Lebaron, Ruth Birner-Gruenberger, Dieter Kressler, Anthony K Henras, Brigitte Pertschy

Nucleic Acids Res. 2022 Sep 23; 50(17): 10053–10077. Published online 2022 Aug 26. doi: 10.1093/nar/gkac724

PMCID:: PMC9508819

Abstract Article PDF–16M

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 853671312.

The RNA helicase Dbp7 promotes domain V/VI compaction and stabilization of inter-domain interactions during early 60S assembly

Gerald Ryan R. Aquino, Philipp Hackert, Nicolai Krogh, Kuan-Ting Pan, Mariam Jaafar, Anthony K. Henras, Henrik Nielsen, Henning Urlaub, Katherine E. Bohnsack, Markus T. Bohnsack

Nat Commun. 2021; 12: 6152. Published online 2021 Oct 22. doi: 10.1038/s41467-021-26208-9

PMCID:: PMC8536713

Abstract Article PDF–3.9M

Select item 809411713.

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

Xue Bessie Su, Menglu Wang, Claudia Schaffner, Olga O. Nerusheva, Dean Clift, Christos Spanos, David A. Kelly, Michael Tatham, Andreas Wallek, Yehui Wu, Juri Rappsilber, A. Arockia Jeyaprakash, Zuzana Storchova, Ronald T. Hay, Adèle L. Marston

J Cell Biol. 2021 Jul 5; 220(7): e202005130. Published online 2021 Apr 30. doi: 10.1083/jcb.202005130

PMCID:: PMC8094117

Abstract Article PDF–8.1M

Select item 775804914.

Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae

Joshua J. Black, Richa Sardana, Ezzeddine W. Elmir, Arlen W. Johnson

PLoS Genet. 2020 Dec; 16(12): e1009215. Published online 2020 Dec 11. doi: 10.1371/journal.pgen.1009215

PMCID:: PMC7758049

Abstract Article PDF–4.9M

Select item 727317715.

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

Fabian den Brave, Lucas V. Cairo, Chandhuru Jagadeesan, Carmen Ruger-Herreros, Axel Mogk, Bernd Bukau, Stefan Jentsch

Cell Rep. 2020 Jun 2; 31(9): 107680. Published online 2020 Jun 2. doi: 10.1016/j.celrep.2020.107680

PMCID:: PMC7273177

Abstract Article

Select item 684668416.

At least two molecules of the RNA helicase Has1 are simultaneously present in pre-ribosomes during ribosome biogenesis

Sivakumar Vadivel Gnanasundram, Isabelle C Kos-Braun, Martin Koš

Nucleic Acids Res. 2019 Nov 18; 47(20): 10852–10864. Published online 2019 Sep 12. doi: 10.1093/nar/gkz767

PMCID:: PMC6846684

Abstract Article PDF–6.9M

Select item 664889517.

Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME

Ingrid Rössler, Julia Embacher, Benjamin Pillet, Guillaume Murat, Laura Liesinger, Jutta Hafner, Julia Judith Unterluggauer, Ruth Birner-Gruenberger, Dieter Kressler, Brigitte Pertschy

Nucleic Acids Res. 2019 Jul 26; 47(13): 6984–7002. Published online 2019 May 7. doi: 10.1093/nar/gkz317

PMCID:: PMC6648895

Abstract Article PDF–14M

Select item 634089618.

Cryo-EM structure of an early precursor of large ribosomal subunit reveals a half-assembled intermediate

Dejian Zhou, Xing Zhu, Sanduo Zheng, Dan Tan, Meng-Qiu Dong, Keqiong Ye

Protein Cell. 2019 Feb; 10(2): 120–130. Published online 2018 Mar 19. doi: 10.1007/s13238-018-0526-7

PMCID:: PMC6340896

Abstract Article PDF–2.8M

Select item 630060219.

RNA helicases mediate structural transitions and compositional changes in pre-ribosomal complexes

Lukas Brüning, Philipp Hackert, Roman Martin, Jimena Davila Gallesio, Gerald Ryan R. Aquino, Henning Urlaub, Katherine E. Sloan, Markus T. Bohnsack

Nat Commun. 2018; 9: 5383. Published online 2018 Dec 19. doi: 10.1038/s41467-018-07783-w

PMCID:: PMC6300602

Abstract Article PDF–3.9M

Select item 611812720.

Modular assembly of the nucleolar pre-60S ribosomal subunit

Zahra Assur Sanghai, Linamarie Miller, Kelly R. Molloy, Jonas Barandun, Mirjam Hunziker, Malik Chaker-Margot, Junjie Wang, Brian T. Chait, Sebastian Klinge

Nature. Author manuscript; available in PMC 2018 Aug 31.

Published in final edited form as: Nature. 2018 Apr 5; 556(7699): 126–129. Published online 2018 Mar 5. doi: 10.1038/nature26156