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Select item 111371111.

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration

Fenglian He, Zhongen Wu, Chenglong Liu, Yuanyuan Zhu, Yan Zhou, Enming Tian, Rina Rosin-Arbesfeld, Dehua Yang, Ming-Wei Wang, Di Zhu

Signal Transduct Target Ther. 2024; 9: 139. Published online 2024 May 29. doi: 10.1038/s41392-024-01838-9

PMCID:: PMC11137111

Abstract Article PDF–1.9M

Select item 91894662.

miRNA‐122‐5p in POI ovarian‐derived exosomes promotes granulosa cell apoptosis by regulating BCL9

Xiujuan Zhang, Ruihong Zhang, Jing Hao, Xiaoyan Huang, Ming Liu, Mengxiao Lv, Chan Su, Yu‐Lan Mu

Cancer Med. 2022 Jun; 11(12): 2414–2426. Published online 2022 Mar 1. doi: 10.1002/cam4.4615

PMCID:: PMC9189466

Abstract Article PDF–3.4M

Select item 89187873.

PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation

Lomeli C. Shull, Ezra S. Lencer, Hyun Min Kim, Susumu Goyama, Mineo Kurokawa, James C. Costello, Kenneth Jones, Kristin B. Artinger

Development. 2022 Feb 15; 149(4): dev200082. Published online 2022 Feb 24. doi: 10.1242/dev.200082

PMCID:: PMC8918787

Abstract Article

Select item 85536204.

The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote breast cancer growth, invasion, and metastasis

Vida Vafaizadeh, David Buechel, Natalia Rubinstein, Ravi K. R. Kalathur, Lorenzo Bazzani, Meera Saxena, Tomas Valenta, George Hausmann, Claudio Cantù, Konrad Basler, Gerhard Christofori

Oncogene. 2021; 40(43): 6195–6209. Published online 2021 Sep 20. doi: 10.1038/s41388-021-02016-9

PMCID:: PMC8553620

Abstract Article PDF–4.7M

Select item 83792535.

BCL9 regulates CD226 and CD96 checkpoints in CD8⁺ T cells to improve PD-1 response in cancer

Mei Feng, Zhongen Wu, Yan Zhou, Zhuang Wei, Enming Tian, Shenglin Mei, Yuanyuan Zhu, Chenglong Liu, Fenglian He, Huiyu Li, Cao Xie, Joy Jin, Jibin Dong, Dehua Yang, Ker Yu, Junbin Qian, Diether Lambrechts, Ming-Wei Wang, Di Zhu

Signal Transduct Target Ther. 2021; 6: 313. Published online 2021 Aug 20. doi: 10.1038/s41392-021-00730-0

PMCID:: PMC8379253

Abstract Article PDF–2.7M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 79213927.

Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells

Costanza Borrelli, Tomas Valenta, Kristina Handler, Karelia Vélez, Alessandra Gurtner, Giulia Moro, Atefeh Lafzi, Laura de Vargas Roditi, George Hausmann, Isabelle C. Arnold, Andreas E. Moor, Konrad Basler

Nat Commun. 2021; 12: 1368. Published online 2021 Mar 1. doi: 10.1038/s41467-021-21591-9

PMCID:: PMC7921392

Abstract Article PDF–17M

Select item 74344418.

TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex

Dario Zimmerli, Costanza Borrelli, Amaia Jauregi-Miguel, Simon Söderholm, Salome Brütsch, Nikolaos Doumpas, Jan Reichmuth, Fabienne Murphy-Seiler, MIchel Aguet, Konrad Basler, Andreas E Moor, Claudio Cantù

eLife. 2020; 9: e58123. Published online 2020 Aug 18. doi: 10.7554/eLife.58123

PMCID:: PMC7434441

Abstract Article PDF–4.6M

Select item 63744459.

Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer

David M. Gay, Rachel A. Ridgway, Miryam Müller, Michael C. Hodder, Ann Hedley, William Clark, Joshua D. Leach, Rene Jackstadt, Colin Nixon, David J. Huels, Andrew D. Campbell, Thomas G. Bird, Owen J. Sansom

Nat Commun. 2019; 10: 723. Published online 2019 Feb 13. doi: 10.1038/s41467-019-08586-3

Correction in:: Nat Commun. 2019; 10: 1453.

PMCID:: PMC6374445

Abstract Article PDF–2.9M

Select item 637440710.

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models

Juliusz Mieszczanek, Laurens M. van Tienen, Ashraf E. K. Ibrahim, Douglas J. Winton, Mariann Bienz

Nat Commun. 2019; 10: 724. Published online 2019 Feb 13. doi: 10.1038/s41467-018-08164-z

PMCID:: PMC6374407

Abstract Article PDF–3.6M

Select item 621773011.

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling

Claudio Cantù, Anastasia Felker, Dario Zimmerli, Karin D. Prummel, Elena M. Cabello, Elena Chiavacci, Kevin M. Méndez-Acevedo, Lucia Kirchgeorg, Sibylle Burger, Jorge Ripoll, Tomas Valenta, George Hausmann, Nathalie Vilain, Michel Aguet, Alexa Burger, Daniela Panáková, Konrad Basler, Christian Mosimann

Genes Dev. 2018 Nov 1; 32(21-22): 1443–1458. doi: 10.1101/gad.315531.118

PMCID:: PMC6217730

Abstract Article PDF–2.8M

Select item 564508212.

Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders

Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba

Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594

PMCID:: PMC5645082

Abstract Article PDF–2.3M

Select item 529099013.

Widespread and dynamic translational control of red blood cell development

Juan R. Alvarez-Dominguez, Xu Zhang, Wenqian Hu

Blood. 2017 Feb 2; 129(5): 619–629. Prepublished online 2016 Nov 29. doi: 10.1182/blood-2016-09-741835

PMCID:: PMC5290990

Abstract Article

Select item 524586714.

Il-Taeg Cho, Youngshin Lim, Jeffrey A. Golden, Ginam Cho

PLoS One. 2017; 12(1): e0170282. Published online 2017 Jan 19. doi: 10.1371/journal.pone.0170282

PMCID:: PMC5245867

Abstract Article PDF–4.1M

Select item 450673915.

GM130 regulates Golgi-derived spindle assembly by activating TPX2 and capturing microtubules

Jen-Hsuan Wei, Zi Chao Zhang, R. Max Wynn, Joachim Seemann

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 287–299. Published online 2015 Jul 9. doi: 10.1016/j.cell.2015.06.014

PMCID:: PMC4506739

Abstract Article PDF–2.5M

Select item 431955916.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 419794817.

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development

Claudio Cantù, Dario Zimmerli, George Hausmann, Tomas Valenta, Andreas Moor, Michel Aguet, Konrad Basler

Genes Dev. 2014 Sep 1; 28(17): 1879–1884. doi: 10.1101/gad.246140.114

PMCID:: PMC4197948

Abstract Article PDF–1.0M

Select item 390107018.

Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation

Juan R. Alvarez-Dominguez, Wenqian Hu, Bingbing Yuan, Jiahai Shi, Staphany S. Park, Austin A. Gromatzky, Alexander van Oudenaarden, Harvey F. Lodish

Blood. 2014 Jan 23; 123(4): 570–581. Prepublished online 2013 Nov 7. doi: 10.1182/blood-2013-10-530683

PMCID:: PMC3901070

Abstract Article

Select item 385292619.

Loss-of-Function Mutations in TBC1D20 Cause Cataracts and Male Infertility in blind sterile Mice and Warburg Micro Syndrome in Humans

Ryan P. Liegel, Mark T. Handley, Adam Ronchetti, Stephen Brown, Lars Langemeyer, Andrea Linford, Bo Chang, Deborah J. Morris-Rosendahl, Sarah Carpanini, Renata Posmyk, Verity Harthill, Eamonn Sheridan, Ghada M.H. Abdel-Salam, Paulien A. Terhal, Francesca Faravelli, Patrizia Accorsi, Lucio Giordano, Lorenzo Pinelli, Britta Hartmann, Allison D. Ebert, Francis A. Barr, Irene A. Aligianis, Duska J. Sidjanin

Am J Hum Genet. 2013 Dec 5; 93(6): 1001–1014. doi: 10.1016/j.ajhg.2013.10.011

PMCID:: PMC3852926

Abstract Article PDF–2.8M

Select item 361727620.

Dynamics of the Rhomboid-like Protein RHBDD2 Expression in Mouse Retina and Involvement of Its Human Ortholog in Retinitis Pigmentosa

Novruz B. Ahmedli, Yekaterina Gribanova, Collins C. Njoku, Akash Naidu, Alejandra Young, Emmanuel Mendoza, Clyde K. Yamashita, Riza Köksal Özgül, Jerry E. Johnson, Donald A. Fox, Debora B. Farber

J Biol Chem. 2013 Apr 5; 288(14): 9742–9754. Published online 2013 Feb 5. doi: 10.1074/jbc.M112.419960

PMCID:: PMC3617276

Abstract Article PDF–3.4M

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